Preface |
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iii | |
Contributors |
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xi | |
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SECTION 1: An Overview of Normal and Abnormal Brain Development |
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1 | (62) |
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Early Development of the Neural Tube |
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3 | (10) |
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3 | (1) |
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Neural Plate Formation and Neurulation |
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3 | (2) |
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5 | (1) |
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Neural Patterning: Ventralization in the Posterior Neural Tube |
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5 | (2) |
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Neural Patterning: Dorsalization of the Caudal Neural Tube and Formation of the Peripheral Nervous System |
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7 | (1) |
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Neural Patterning: Ventralization of the Rostral Neural Tube |
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7 | (1) |
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Prechordal Mesoderm and Development of the Hypothalamo-Pituitary Axis |
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8 | (1) |
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Shh and Holoprosencephaly |
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9 | (2) |
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11 | (1) |
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11 | (2) |
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13 | (14) |
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13 | (1) |
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13 | (1) |
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14 | (2) |
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Failure of Commissuration (Agenesis/Hypogenesis of the Corpus Callosum) |
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16 | (2) |
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18 | (1) |
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Malformations Associated with Failed Commissuration |
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18 | (2) |
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Abnormalities of Cortical Formation |
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20 | (6) |
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26 | (1) |
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27 | (12) |
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27 | (10) |
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37 | (2) |
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Studies of Malformations of the Posterior Fossa |
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39 | (10) |
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Studies of Malformations of the Posterior Fossa |
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39 | (8) |
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47 | (2) |
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Imaging Developmental Brain Abnormalities in Children |
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49 | (14) |
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49 | (1) |
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50 | (1) |
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50 | (1) |
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51 | (1) |
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Entertaining the Older Child |
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51 | (1) |
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51 | (1) |
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51 | (9) |
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60 | (1) |
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61 | (2) |
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SECTION 2: Fetal Neuroimaging |
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63 | (70) |
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Ultrasound Methods and Anatomy |
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65 | (6) |
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69 | (2) |
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Developmental Abnormalities of the Brain Shown by Ultrasound |
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71 | (10) |
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71 | (1) |
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71 | (2) |
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73 | (1) |
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Ventriculomegaly and Hydrocephalus |
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74 | (2) |
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76 | (1) |
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Agenesis of the Corpus Callosum |
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77 | (1) |
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Dandy--Walker Malformation |
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78 | (1) |
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Arterio-Venous Malformations |
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78 | (1) |
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79 | (1) |
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79 | (1) |
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Destructive (Acquired) Lesions |
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79 | (1) |
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79 | (2) |
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Magnetic Resonance Imaging Methods and Anatomy |
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81 | (18) |
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Imaging the Developing Fetus |
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81 | (7) |
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88 | (8) |
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96 | (3) |
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In Utero Magnetic Resonance Imaging of Developmental Abnormalities of the Fetal CNS |
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99 | (12) |
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99 | (1) |
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99 | (3) |
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Failure of Commissuration |
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102 | (3) |
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Abnormalities Associated with Failure of Commissuration |
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105 | (4) |
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109 | (1) |
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109 | (2) |
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The Balance Between Magnetic Resonance Imaging and Ultrasound |
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111 | (4) |
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Safety of Ultrasound and MRI |
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112 | (1) |
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113 | (2) |
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In Utero Magnetic Resonance Imaging of Developmental Abnormalities of the Fetal Cerebellum |
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115 | (18) |
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Development of the Cerebellum Shown by MRI of Fetal Specimens |
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115 | (2) |
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Early Development of the Cerebellum Shown by MRI In Utero |
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117 | (2) |
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Systematic Approach to Analysis of Vermian Development |
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119 | (1) |
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120 | (1) |
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121 | (9) |
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130 | (1) |
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130 | (3) |
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SECTION 3: Neonatal Neuroimaging |
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133 | (66) |
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Neonatal Cranial Ultrasound |
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135 | (24) |
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Limitations of Ultrasound |
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135 | (2) |
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Hazards of Neonatal Ultrasound |
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137 | (1) |
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138 | (1) |
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138 | (2) |
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140 | (6) |
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Pitfalls and Limitations of Ultrasound Scanning |
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146 | (1) |
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Surface (Near Field) Imaging |
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146 | (2) |
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Doppler and Other Ultrasound Scanning Developments |
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148 | (3) |
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Assessment of Ventricular Dilatation |
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151 | (2) |
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153 | (1) |
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Use of Cranial Ultrasound Outside the Neonatal Period |
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153 | (1) |
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Ultrasound and Spinal Imaging |
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154 | (1) |
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Comparison with Other Imaging Modalities |
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154 | (3) |
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157 | (1) |
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158 | (1) |
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Magnetic Resonance Imaging of the Neonatal Brain |
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159 | (8) |
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Magnetic Resonance Imaging (MRI) of the Neonatal Brain |
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159 | (5) |
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164 | (1) |
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164 | (3) |
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Neonatal Hypoxic Ischemic Brain Injury |
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167 | (20) |
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Hypoxic Ischemic Brain Injury |
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167 | (1) |
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167 | (2) |
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Hypoxic Ischemic Brain Injury |
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169 | (1) |
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HIBI in the Preterm Infants |
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170 | (1) |
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Imaging of Periventricular Leukomalacia |
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171 | (3) |
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174 | (1) |
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Imaging of HIBI in Term Infants |
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175 | (3) |
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MRI Findings of Central Cortical-Subcortical Injury |
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178 | (1) |
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MRI Findings of Parasagittal Injury |
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179 | (1) |
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180 | (1) |
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181 | (6) |
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Imaging Intracranial Hemorrhage in the Neonate and Infant |
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187 | (12) |
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Anatomy of Intracranial Hemorrhage |
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187 | (1) |
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187 | (1) |
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188 | (1) |
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189 | (2) |
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Examples of the Application of Different Imaging Methods in Neonatal Intracranial Hemorrhage |
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191 | (6) |
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197 | (1) |
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197 | (2) |
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199 | (58) |
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Advances in Fetal Ultrasound |
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201 | (2) |
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202 | (1) |
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Expected Developments in In Utero Magnetic Resonance Imaging of the Fetal Central Nervous System |
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203 | (8) |
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203 | (5) |
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208 | (3) |
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Emerging Options for Imaging Neonatal Anatomy and Function |
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211 | (22) |
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211 | (1) |
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Review of Neonatal MRI Using Conventional MRI Systems |
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211 | (2) |
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The Role of Dedicated MRI Systems Located on the Intensive Care Unit |
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213 | (1) |
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Dedicated Neonatal MRI System Design Considerations |
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213 | (2) |
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Neonatal Imaging Sequence Considerations |
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215 | (2) |
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Neonatal Medication and Monitoring for Dedicated MRI Systems |
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217 | (1) |
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Practical Aspects of Neonatal Imaging with a Dedicated MRI System |
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217 | (1) |
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Novel Technique Developments for Neonatal Imaging and Spectroscopy |
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217 | (8) |
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225 | (1) |
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225 | (8) |
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Incubators for Magnetic Resonance Imaging Use |
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233 | (12) |
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233 | (1) |
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Basics of Warming Therapy |
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233 | (1) |
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Requirements for a MRI-Compatible Incubator |
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234 | (6) |
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Design Considerations: Coils |
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240 | (1) |
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241 | (1) |
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242 | (1) |
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The Technical Challenge: 3T and Improved Coils |
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242 | (1) |
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243 | (2) |
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The Role of the Magnetic Resonance Imaging Post-Mortem of the Fetus and Neonate |
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245 | (12) |
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The Role of Magnetic Resonance Imaging Post-Mortem in the Fetus and Neonate |
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245 | (10) |
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255 | (2) |
Index |
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257 | |