Preface |
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xv | |
About the Author |
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xvii | |
New to This Edition |
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xix | |
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Chapter 1 The Health Research Process |
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1 | (4) |
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1.1 Clinical and Population Health Research |
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1 | (1) |
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2 | (1) |
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2 | (3) |
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STEP 1 Identifying a Study Question |
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5 | (36) |
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Chapter 2 Selecting a Research Question |
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7 | (10) |
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7 | (1) |
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2.2 Brainstorming and Concept Mapping |
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8 | (1) |
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8 | (1) |
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2.4 Exposures, Diseases, and Populations (EDPs) |
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9 | (2) |
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11 | (1) |
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2.6 From Inquiry to Research |
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12 | (2) |
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14 | (1) |
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2.8 Framing for Generalizability |
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14 | (3) |
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Chapter 3 Reviewing the Literature |
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17 | (8) |
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17 | (1) |
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17 | (1) |
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18 | (2) |
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20 | (1) |
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21 | (1) |
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3.6 Annotated Bibliographies |
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22 | (1) |
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3.7 What Makes Research Original? |
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22 | (3) |
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Chapter 4 Defining Specific Aims |
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25 | (6) |
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4.1 Refining the Study Question |
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25 | (1) |
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25 | (1) |
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4.3 Several Specific Aims |
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26 | (1) |
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4.4 Conceptual and Theoretical Frameworks |
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27 | (1) |
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28 | (3) |
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Chapter 5 Professional Development |
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31 | (6) |
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31 | (1) |
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5.2 Finding Research Mentors |
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32 | (1) |
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5.3 The Mentor-Mentee Relationship |
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32 | (1) |
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5.4 Professional Development |
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33 | (1) |
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5.5 Social Media and Impact Metrics |
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33 | (1) |
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5.6 Responsible Conduct of Research |
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34 | (3) |
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37 | (4) |
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37 | (1) |
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38 | (1) |
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39 | (1) |
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6.4 Decisions About Authorship |
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40 | (1) |
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STEP 2 Selecting a Study Approach |
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41 | (78) |
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Chapter 7 Overview of Study Designs |
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43 | (8) |
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7.1 Types of Study Approaches |
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43 | (1) |
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7.2 Primary, Secondary, and Tertiary Studies |
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43 | (3) |
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7.3 Observational and Experimental Studies |
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46 | (1) |
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7.4 Exposure, Disease, or Population? |
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47 | (1) |
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48 | (3) |
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51 | (6) |
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51 | (1) |
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52 | (1) |
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53 | (1) |
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8.4 Ethical Considerations |
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54 | (1) |
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54 | (3) |
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Chapter 9 Cross-Sectional Studies |
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57 | (4) |
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57 | (1) |
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9.2 Representative Populations |
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57 | (1) |
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58 | (1) |
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9.4 Repeated Cross-Sectional Surveys |
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58 | (1) |
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59 | (2) |
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Chapter 10 Case--Control Studies |
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61 | (10) |
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61 | (1) |
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10.2 Finding Cases and Controls |
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61 | (2) |
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63 | (1) |
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64 | (1) |
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65 | (4) |
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10.6 Matched Case--Control Studies |
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69 | (2) |
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Chapter 11 Cohort Studies |
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71 | (14) |
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71 | (2) |
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11.2 Prospective Cohort Studies |
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73 | (1) |
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11.3 Retrospective Cohort Studies |
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73 | (1) |
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11.4 Longitudinal Cohort Studies |
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74 | (1) |
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75 | (1) |
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11.6 Ratios, Rates, and Risk |
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76 | (1) |
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76 | (2) |
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11.8 Incidence Rate Ratios |
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78 | (1) |
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79 | (3) |
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11.10 Person--Time Analysis |
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82 | (3) |
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Chapter 12 Experimental Studies |
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85 | (16) |
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85 | (1) |
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12.2 Describing the Intervention |
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86 | (1) |
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87 | (1) |
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88 | (3) |
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91 | (1) |
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91 | (2) |
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12.7 Ethical Considerations |
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93 | (1) |
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94 | (2) |
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12.9 Screening and Diagnostic Tests |
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96 | (5) |
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Chapter 13 Qualitative Studies |
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101 | (6) |
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101 | (1) |
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13.2 Ontology, Epistemology, and Axiology |
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102 | (1) |
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13.3 Theoretical Paradigms |
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103 | (1) |
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13.4 Qualitative Methodologies |
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104 | (1) |
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13.5 Mixed Methods Research |
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105 | (2) |
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Chapter 14 Correlational Studies |
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107 | (8) |
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107 | (1) |
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108 | (1) |
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14.3 Avoiding the Ecological Fallacy |
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109 | (1) |
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110 | (1) |
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111 | (4) |
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Chapter 15 Synthesis Research |
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115 | (4) |
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115 | (2) |
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117 | (1) |
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117 | (1) |
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117 | (1) |
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117 | (1) |
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118 | (1) |
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118 | (1) |
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STEP 3 Designing the Study and Collecting Data |
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119 | (106) |
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Chapter 16 Research Protocols |
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121 | (6) |
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16.1 Overview of Research Plans by Study Approach |
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121 | (1) |
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16.2 Writing a Research Protocol |
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121 | (2) |
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16.3 Rigor and Reproducibility |
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123 | (1) |
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124 | (2) |
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16.5 Roles and Responsibilities |
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126 | (1) |
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16.6 Preparing for Data Collection |
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126 | (1) |
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Chapter 17 Ethical Considerations |
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127 | (12) |
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17.1 Foundations of Research Ethics |
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127 | (1) |
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17.2 Respect, Beneficence, and Justice |
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128 | (1) |
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17.3 Incentives and Coercion |
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129 | (3) |
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17.4 Informed Consent Statements |
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132 | (1) |
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17.5 Informed Consent Process |
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133 | (1) |
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17.6 Informed Consent Documentation |
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133 | (1) |
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17.7 Confidentiality and Privacy |
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134 | (1) |
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135 | (1) |
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17.9 Cultural Considerations |
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136 | (1) |
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17.10 Vulnerable Populations |
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137 | (1) |
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17.11 Ethics Training and Certification |
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137 | (2) |
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Chapter 18 Ethical Review and Approval |
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139 | (8) |
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18.1 Ethics Committee Responsibilities |
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139 | (1) |
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18.2 Ethics Committee Composition |
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140 | (1) |
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18.3 Application Materials |
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140 | (2) |
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18.4 Exemption from Review |
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142 | (1) |
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143 | (1) |
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18.6 Review by Multiple Committees |
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143 | (1) |
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144 | (1) |
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18.8 Conflicts of Interest |
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145 | (1) |
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18.9 Is Ethics Review Required? |
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145 | (2) |
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Chapter 19 Population Sampling |
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147 | (12) |
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19.1 Types of Research Populations |
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147 | (1) |
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19.2 Target and Source Populations |
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148 | (1) |
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148 | (2) |
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150 | (1) |
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19.5 Populations for Cross-Sectional Studies |
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150 | (2) |
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19.6 Populations for Case--Control Studies |
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152 | (1) |
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19.7 Populations for Cohort Studies |
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153 | (2) |
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19.8 Populations for Experimental Studies |
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155 | (1) |
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19.9 Sampling for Qualitative Studies |
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156 | (1) |
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19.10 Vulnerable Populations |
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156 | (1) |
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19.11 Community Involvement |
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157 | (2) |
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Chapter 20 Sample Size and Power |
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159 | (8) |
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20.1 Importance of Sample Size |
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159 | (1) |
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20.2 Sample Size and Certainty Levels |
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159 | (2) |
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20.3 Sample Size Estimation |
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161 | (1) |
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20.4 Type 1 and Type 2 Errors |
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161 | (2) |
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163 | (2) |
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20.6 Refining the Study Approach |
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165 | (2) |
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Chapter 21 Questionnaire Development |
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167 | (16) |
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21.1 Questionnaire Design Overview |
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167 | (1) |
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21.2 Questionnaire Content |
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168 | (1) |
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169 | (2) |
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171 | (2) |
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173 | (1) |
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21.6 Wording of Questions |
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173 | (2) |
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175 | (1) |
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21.8 Layout and Formatting |
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176 | (1) |
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21.9 Reliability and Validity |
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177 | (4) |
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21.10 Commercial Research Tools |
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181 | (1) |
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181 | (1) |
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182 | (1) |
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Chapter 22 Collecting Quantitative Data |
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183 | (6) |
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22.1 Interviews Versus Self-Administered Surveys |
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183 | (1) |
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184 | (1) |
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22.3 Encouraging Participation |
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184 | (1) |
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22.4 Data Recording Methods |
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185 | (2) |
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22.5 Training Interviewers |
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187 | (2) |
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Chapter 23 Collecting Qualitative Data |
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189 | (6) |
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189 | (1) |
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189 | (1) |
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23.3 Focus Group Discussions |
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190 | (1) |
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23.4 Observational Methods |
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191 | (1) |
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23.5 Other Qualitative Research Techniques |
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192 | (1) |
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23.6 Community-Based Participatory Research |
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192 | (1) |
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193 | (2) |
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Chapter 24 Additional Assessments |
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195 | (6) |
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24.1 Supplementing Self-Reported Data |
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195 | (1) |
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24.2 Anthropometric Measures |
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195 | (1) |
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196 | (1) |
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24.4 Clinical Examination |
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196 | (1) |
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24.5 Tests of Physiological Function |
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197 | (1) |
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24.6 Laboratory Analysis of Biological Specimens |
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197 | (1) |
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197 | (1) |
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24.8 Tests of Physical Fitness |
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198 | (1) |
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24.9 Environmental Assessment |
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198 | (1) |
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24.10 Geographic Information Systems |
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199 | (1) |
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24.11 Monitoring and Evaluation |
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199 | (2) |
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Chapter 25 Secondary Analyses |
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201 | (6) |
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25.1 Overview of Secondary Analysis |
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201 | (1) |
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25.2 Accessing Secondary Data |
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201 | (1) |
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25.3 Publicly Available Data Sets |
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202 | (1) |
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203 | (1) |
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25.5 Challenges of Secondary Research |
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203 | (1) |
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204 | (1) |
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25.7 Health Informatics, Big Data, and Data Mining |
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204 | (1) |
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25.8 Ethics Committee Review |
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205 | (2) |
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Chapter 26 Systematic Reviews and Meta-analyses |
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207 | (10) |
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26.1 Overview of Tertiary Analysis |
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207 | (1) |
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207 | (2) |
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209 | (1) |
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26.4 Supplemental Searches |
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210 | (1) |
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26.5 Eligibility Criteria |
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210 | (1) |
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211 | (1) |
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212 | (1) |
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26.8 Systematic Review Results |
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212 | (1) |
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213 | (1) |
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26.10 Forest Plots and Funnel Plots |
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214 | (3) |
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Chapter 27 Writing Grant Proposals |
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217 | (8) |
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27.1 Preparing to Write a Proposal |
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217 | (1) |
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27.2 Identifying Grant Opportunities |
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217 | (1) |
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27.3 Requests for Proposals |
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218 | (1) |
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27.4 Research Proposal Components |
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219 | (1) |
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27.5 Writing a Research Narrative |
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220 | (1) |
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221 | (1) |
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222 | (1) |
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27.8 Financial Accounting |
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223 | (1) |
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224 | (1) |
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224 | (1) |
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225 | (62) |
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Chapter 28 Data Management |
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227 | (8) |
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227 | (1) |
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227 | (2) |
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229 | (1) |
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230 | (1) |
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231 | (1) |
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28.6 Statistical Software Programs |
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231 | (1) |
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232 | (3) |
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Chapter 29 Descriptive Statistics |
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235 | (12) |
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29.1 Analytic Plan by Study Approach |
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235 | (1) |
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236 | (1) |
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29.3 Measures of Central Tendency |
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237 | (1) |
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238 | (1) |
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29.5 Displaying Distributions |
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238 | (2) |
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29.6 Normal Curves, Variance, and Standard Deviation |
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240 | (3) |
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29.7 Reporting Descriptive Statistics |
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243 | (1) |
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29.8 Confidence Intervals |
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243 | (1) |
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244 | (1) |
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29.10 Statistical Consultants |
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245 | (2) |
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Chapter 30 Comparative Statistics |
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247 | (16) |
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30.1 Comparative Analysis by Study Approach |
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247 | (1) |
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30.2 Hypotheses for Statistical Tests |
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248 | (1) |
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30.3 Rejecting the Null Hypothesis |
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248 | (2) |
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30.4 Interpreting ρ Values |
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250 | (1) |
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30.5 Measures of Association |
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251 | (2) |
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30.6 Interpreting Confidence Intervals |
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253 | (1) |
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30.7 Selecting an Appropriate Test |
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254 | (1) |
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30.8 Parametric and Nonparametric Tests |
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255 | (1) |
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30.9 Comparing a Population Statistic to a Set Value |
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255 | (1) |
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30.10 Comparing Independent Populations |
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256 | (2) |
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30.11 Multivariable Comparisons of Means |
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258 | (2) |
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30.12 Correlation Analysis |
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260 | (1) |
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30.13 Comparing Paired Data |
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260 | (3) |
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Chapter 31 Regression Analysis |
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263 | (14) |
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263 | (1) |
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31.2 Simple Linear Regression |
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264 | (1) |
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31.3 Simple Logistic Regression |
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265 | (2) |
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267 | (1) |
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31.5 Confounding and Effect Modification |
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267 | (3) |
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270 | (3) |
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273 | (2) |
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275 | (1) |
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276 | (1) |
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Chapter 32 Qualitative Analysis |
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277 | (4) |
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277 | (1) |
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32.2 Analytic and Interpretive Frameworks |
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278 | (1) |
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32.3 Codes, Categories, and Themes |
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278 | (2) |
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32.4 Manual and Electronic Coding |
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280 | (1) |
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280 | (1) |
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Chapter 33 Additional Analysis Tools |
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281 | (6) |
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281 | (1) |
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281 | (1) |
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33.3 Mathematical Modeling |
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282 | (1) |
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33.4 Agent-Based Modeling |
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283 | (1) |
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283 | (1) |
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33.6 Cost-Effectiveness Analysis |
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284 | (1) |
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33.7 Burden of Disease Metrics |
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285 | (2) |
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STEP 5 Reporting Findings |
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287 | (68) |
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Chapter 34 Posters and Presentations |
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289 | (10) |
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34.1 Purpose of Conferences |
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289 | (1) |
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34.2 Structure of Conferences |
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289 | (1) |
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290 | (1) |
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34.4 Submitting an Abstract |
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291 | (1) |
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291 | (2) |
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293 | (1) |
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293 | (1) |
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34.8 Preparing for an Oral Presentation |
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294 | (2) |
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34.9 Giving an Oral Presentation |
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296 | (3) |
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Chapter 35 Article Structure |
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299 | (10) |
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35.1 Outlining a Manuscript |
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299 | (1) |
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300 | (1) |
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301 | (1) |
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302 | (1) |
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303 | (1) |
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303 | (1) |
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304 | (1) |
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305 | (1) |
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306 | (3) |
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309 | (8) |
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36.1 Referring to the Scientific Literature |
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309 | (1) |
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36.2 Formal and Informal Sources |
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310 | (2) |
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36.3 Writing in One's Own Words |
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312 | (1) |
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36.4 Common Knowledge and Specific Knowledge |
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312 | (1) |
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313 | (1) |
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314 | (3) |
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Chapter 37 Critically Revising |
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317 | (4) |
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37.1 Clarifying the Storyline |
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317 | (1) |
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37.2 One Paper, One Story |
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318 | (1) |
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37.3 Structure and Content |
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318 | (1) |
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37.4 Style, Clarity, and Consistency |
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319 | (2) |
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Chapter 38 Writing Success Strategies |
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321 | (8) |
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321 | (1) |
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321 | (2) |
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323 | (1) |
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38.4 Conquering Writer's Block |
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324 | (2) |
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38.5 Finishing a Manuscript |
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326 | (3) |
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Chapter 39 Reasons to Publish |
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329 | (4) |
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329 | (1) |
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329 | (1) |
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39.3 Respect for Participants and Collaborators |
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330 | (1) |
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330 | (3) |
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Chapter 40 Selecting Target Journals |
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333 | (8) |
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40.1 Choosing a Target Journal |
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333 | (1) |
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40.2 Aim, Scope, and Audience |
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333 | (1) |
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334 | (1) |
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40.4 Other Journal Characteristics |
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335 | (1) |
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40.5 Open Access and Copyright |
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336 | (2) |
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338 | (1) |
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338 | (3) |
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Chapter 41 Manuscript Submission |
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341 | (6) |
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341 | (1) |
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341 | (1) |
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41.3 Manuscript Formatting |
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342 | (2) |
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344 | (1) |
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345 | (2) |
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Chapter 42 Peer Review and Publication |
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347 | (8) |
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347 | (1) |
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42.2 External Review Results |
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348 | (1) |
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349 | (1) |
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42.4 Revision and Resubmission |
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350 | (3) |
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353 | (2) |
Glossary |
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355 | (38) |
Index |
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393 | |