Contributors |
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ix | |
Foreword |
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xix | |
Obituary |
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xxi | |
Preface |
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xxiii | |
Abbreviations |
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xxv | |
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Part 1 Penicillins and Related Drugs |
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Benzylpenicillin (Penicillin G) |
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5 | (54) |
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59 | (6) |
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Ampicillin, Amoxicillin and Other Ampicillin-Like Penicillins |
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65 | (28) |
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93 | (7) |
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Isoxazolyl Pencillins: Oxacillin, Cloxacillin, Dicloxacillin and Flucloxacillin |
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100 | (15) |
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115 | (8) |
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Carbenicillin, Carindacillin, Carfecillin and Ticarcillin |
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123 | (12) |
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Mezlocillin, Azlocillin, Apalcillin and Piperacillin |
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135 | (17) |
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Mecillinam (Amdinocillin) and Pivmecillinam |
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152 | (8) |
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160 | (7) |
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Beta-Lactamase Inhibitors and Combinations |
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167 | (8) |
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175 | (5) |
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180 | (7) |
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Amoxicillin-Clavulanic Acid (Co-Amoxiclav) |
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187 | (17) |
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204 | (17) |
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Ticarcillin-Clavulanic Acid |
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221 | (17) |
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238 | (19) |
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Part 2 Cephalosporins and Related Drugs |
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Cephalothin and Cefazolin |
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257 | (11) |
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268 | (7) |
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Cephadroxil, Cephaloridine, Cephacetrile, Cephapirin, Cephradine, and Other Rarely Used First-Generation Cephalosporins |
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275 | (5) |
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Cefaclor, Cefprozil, and Loracarbef |
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280 | (6) |
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286 | (9) |
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Cefotiam, Cefuzonam, Cefamandole, Cefonicid and Ceforanide |
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295 | (6) |
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Cefoxitin, Cefotetan and Other Cephamycins (Cefmetazole and Flomoxef) |
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301 | (10) |
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Cefoperazone and Cefoperazone-Sulbactam |
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311 | (8) |
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319 | (32) |
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351 | (39) |
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Ceftizoxime, Cefdinir, Cefditoren, Cefpodoxime, Ceftibuten, Cefsulodin, and Cefpiramide |
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390 | (8) |
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398 | (7) |
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405 | (17) |
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422 | (5) |
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427 | (15) |
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442 | (6) |
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448 | (10) |
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458 | (13) |
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471 | (29) |
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500 | (14) |
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514 | (12) |
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526 | (16) |
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542 | (5) |
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547 | (6) |
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553 | (5) |
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558 | (4) |
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562 | (7) |
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Part 4 Glycopeptides and Lipopetides |
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569 | (32) |
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601 | (20) |
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621 | (17) |
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638 | (7) |
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645 | (9) |
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654 | (7) |
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661 | (6) |
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667 | (7) |
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674 | (25) |
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699 | (13) |
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712 | (15) |
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727 | (9) |
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736 | (6) |
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742 | (9) |
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Part 6 Macrolides and Ketolides |
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751 | (19) |
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770 | (9) |
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779 | (22) |
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801 | (18) |
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Josamycin and Rosaramicin |
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819 | (6) |
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825 | (9) |
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834 | (9) |
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Part 7 Tetracyclines and Related Drugs |
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843 | (8) |
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851 | (19) |
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870 | (11) |
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881 | (14) |
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895 | (25) |
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Quinupristin-Dalfopristin |
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920 | (117) |
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930 | (5) |
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935 | (10) |
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Fusidic Acid (Fusidate Sodium) |
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945 | (10) |
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955 | (16) |
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971 | (4) |
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Bacitracin and Gramicidin |
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975 | (5) |
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980 | (7) |
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Lincomycin and Clindamycin |
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987 | (21) |
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Chloramphenicol and Thiamphenicol |
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1008 | (22) |
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1030 | (7) |
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Part 9 Anti-Folate Agents and Other Synthetic Antibacterials |
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1037 | (39) |
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Trimethoprim, Co-Trimoxazole (Co-T) and Related Agents |
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1076 | (74) |
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1150 | (14) |
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1164 | (18) |
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1182 | (5) |
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1187 | (8) |
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Nitrofurans: Nitrofurazone, Furazolidone and Nitrofurantoin |
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1195 | (10) |
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Methenamine Mandelate and Methenamine Hippurate |
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1205 | (6) |
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1211 | (27) |
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1238 | (11) |
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Part 11 Quinolones and Fluoroquinolones |
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Nalidixic Acid and Other Older Quinolones |
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1249 | (16) |
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1265 | (82) |
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1347 | (15) |
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1362 | (34) |
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1396 | (16) |
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1412 | (17) |
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1429 | (23) |
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1452 | (14) |
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1466 | (9) |
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1475 | (7) |
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1482 | (8) |
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1490 | (11) |
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1501 | (8) |
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1509 | (8) |
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1517 | (4) |
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1521 | (5) |
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1526 | (12) |
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Newer, Discontinued Fluoroquinolones: Temfloxacin, Trovafloxacin, Grepafloxacin, and Clinafloxacin |
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1538 | (11) |
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Part 12 Anti-Tuberculous Drugs |
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1549 | (21) |
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1570 | (11) |
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1581 | (6) |
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1587 | (40) |
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1627 | (10) |
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1637 | (8) |
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1645 | (5) |
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1650 | (12) |
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Para-Aminosalicylic Acid (PAS) |
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1662 | (4) |
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Ethionamide and Prothionamide |
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1666 | (6) |
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1672 | (5) |
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1677 | (4) |
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1681 | (6) |
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1687 | (6) |
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Section II ANTI-FUNGAL DRUGS |
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Amphotericin B (AMP): Deoxycholate and Lipid Formulations |
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1693 | (35) |
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1728 | (5) |
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1733 | (6) |
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Part 2 Echinocandins, Allylamines and Benzylamine Derivatives |
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Echinocandins - Caspofungin, Anidulafungin and Micafungin |
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1739 | (24) |
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1763 | (9) |
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1772 | (4) |
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1776 | (5) |
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1781 | (25) |
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1806 | (18) |
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1824 | (20) |
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1844 | (8) |
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1852 | (10) |
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1862 | (9) |
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1871 | (6) |
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1877 | (5) |
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1882 | (7) |
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1889 | (4) |
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1893 | (3) |
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1896 | (7) |
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1903 | (2) |
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1905 | (2) |
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1907 | (4) |
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1911 | (1) |
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1912 | (3) |
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1915 | (2) |
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1917 | (2) |
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1919 | (2) |
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1921 | (2) |
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1923 | (3) |
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1926 | (4) |
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1930 | (3) |
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1933 | (3) |
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1936 | (3) |
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1939 | (4) |
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Part 5 Topical Agents - Thiocarbamates, Hydroxypridones and Morpholine |
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1943 | (2) |
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1945 | (4) |
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1949 | (4) |
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1953 | (4) |
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Part 6 Other Antifungal Agents and New Agents in Development |
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Flucytosine (5-Fluorocytosine; 5-FC) |
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1957 | (7) |
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1964 | (6) |
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1970 | (2) |
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New Agents in Development - Nikkomycin Z, CAY-1, Sodarins, Butenolides, Enfungumab, Inositol Phosphocer-amide Synthase Inhibitors |
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1972 | (17) |
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Section III ANTI - PARASITIC DRUGS |
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Part 1 Anti-Malarial Agents |
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1989 | (14) |
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2003 | (8) |
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2011 | (13) |
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2024 | (12) |
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2036 | (6) |
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2042 | (7) |
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2049 | (10) |
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2059 | (9) |
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2068 | (5) |
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2073 | (9) |
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Proguanil and Chloroproguanil |
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2082 | (8) |
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2090 | (17) |
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Part 2 Agents Active Against Intestinal and Intra-Abdominal Protozoa |
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Iodoquinol and Quinacrine |
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2107 | (3) |
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2110 | (4) |
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Furazolidone (Furazolidine) |
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2114 | (7) |
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2121 | (4) |
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2125 | (7) |
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2132 | (8) |
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2140 | (11) |
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Part 3 Agents Active Against American Trypanosomiasis |
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2151 | (4) |
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2155 | (12) |
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Part 4 Agents Active Against African Trypanosomiasis |
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2167 | (10) |
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2177 | (12) |
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2189 | (14) |
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Part 5 Agents Active Against Leishmania and Other Pathogens |
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2203 | (5) |
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2208 | (6) |
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2214 | (13) |
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Part 6 Agents Active Against Helminths |
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2227 | (13) |
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2240 | (6) |
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2246 | (4) |
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2250 | (4) |
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2254 | (9) |
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2263 | (9) |
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2272 | (4) |
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2276 | (9) |
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2285 | (4) |
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2289 | (4) |
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2293 | (6) |
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Part 7 Agents Active Against Ectoparasites |
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2299 | (7) |
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2306 | (4) |
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2310 | (8) |
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2318 | (7) |
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2325 | (8) |
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Section IV ANTI-VIRAL DRUGS |
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Part 1 Agents Active Against Herpesviruses |
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2333 | (28) |
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2361 | (9) |
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Famciclovir and Penciclovir |
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2370 | (8) |
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Ganciclovir and Valganciclovir |
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2378 | (25) |
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2403 | (26) |
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2429 | (4) |
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2433 | (23) |
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2456 | (5) |
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Trifluridine (Trifluorothymidine) |
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2461 | (4) |
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2465 | (5) |
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2470 | (9) |
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Part 2 Agents Active Against the Human Immunodeficiency Virus |
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Inhibitors of Reserve Transcriptase |
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2479 | (33) |
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2512 | (21) |
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2533 | (12) |
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2545 | (18) |
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2563 | (12) |
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2575 | (20) |
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2595 | (18) |
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2613 | (14) |
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2627 | (9) |
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2636 | (9) |
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Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) |
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2645 | (30) |
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2675 | (27) |
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2702 | (9) |
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2711 | (12) |
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2723 | (8) |
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Inhibitors of HIV Protease |
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2731 | (28) |
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2759 | (17) |
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2776 | (12) |
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2788 | (9) |
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2797 | (12) |
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Amprenavir and Fosamprenavir |
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2809 | (15) |
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2824 | (6) |
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2830 | (12) |
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2842 | (19) |
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2861 | (8) |
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2869 | (8) |
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Raltegravir and Other HIV Integrase Inhibitors |
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2877 | (14) |
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Part 3 Agents Active Against Hepatitis Viruses |
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2891 | (8) |
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2899 | (9) |
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2908 | (7) |
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Torcitabine and Valtorcitabine |
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2915 | (3) |
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2918 | (5) |
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2923 | (36) |
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Pegylated Interferon Alfa |
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2959 | (17) |
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Protease and Polymerase Inhibitors for the Treatment of Hepatitis C Virus Infection |
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2976 | (17) |
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Part 4 Agents Active Against Respiratory Viruses |
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Amantadine and Rimantadine |
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2993 | (20) |
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Zanamivir and Polymeric Zanamivir Conjugates |
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3013 | (16) |
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3029 | (14) |
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3043 | (8) |
Index |
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3051 | |