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Materials and Devices for Bone Disorders [Kietas viršelis]

Edited by (School of Mechanical and Materials Engineering, Washington State University Pullman, WA, USA), Edited by (School of Mechanical and Materials Engineering, Washington State University, Pullman, WA, USA)
  • Formatas: Hardback, 560 pages, aukštis x plotis: 235x191 mm, weight: 1840 g
  • Išleidimo metai: 25-Nov-2016
  • Leidėjas: Academic Press Inc
  • ISBN-10: 0128027924
  • ISBN-13: 9780128027929
Kitos knygos pagal šią temą:
Materials and Devices for Bone DisordersDidesnis paveikslėlis
  • Formatas: Hardback, 560 pages, aukštis x plotis: 235x191 mm, weight: 1840 g
  • Išleidimo metai: 25-Nov-2016
  • Leidėjas: Academic Press Inc
  • ISBN-10: 0128027924
  • ISBN-13: 9780128027929
Kitos knygos pagal šią temą:
Pastovi nuoroda: https://www.kriso.lt/db/9780128027929.html
Raktažodžiai:

Materials for Bone Disorders is written by a cross-disciplinary team of research scientists, engineers, and clinicians and bridges the gap between materials science and bone disorders, providing integrated coverage of biomaterials and their applications. The bioceramics, biopolymers, composites, and metallic materials used in the treatment of bone disorders are introduced, as are their interactions with cells, biomolecules, and body tissues. The main types of bone disorder and disease are covered including osteoporosis, spinal injury, load bearing joint diseases, bone cancer, and forms of cranio-maxillofacial disorders.

Bone disorders are common across all ages. Various forms of bone disorders can change the lifestyle of otherwise normal and healthy people. With the development of novel materials, many forms of bone disorders are becoming manageable, allowing people to lead a fairly normal life. Specific consideration is given to areas where recent advances are enabling new treatments, such as the use of resorbable ceramics in bone tissue engineering and drug delivery, newer polymer-based implants in load-bearing contexts, and engineering biomaterials surfaces including modifying surface chemistry. Ethical and regulatory issues are also explored.

  • Explores biomaterials for bone repair and related applications in orthopedics and dentistry in a clinical context
  • Introduces biomaterials applications in the context of specific diseases, bone disorders, and theraputic contexts
  • Includes input from a world-class team of research scientists, engineers, and clinicians
  • Covers the main types of bone disorder and disease including osteoporosis, spinal injury, load bearing joint diseases, bone cancer, and forms of cranio-maxillofacial disorders

Daugiau informacijos

A team of research scientists, engineers, and clinicians examines bioceramics, biopolymers, composites, and metallic materials used in the treatment of bone disorders, including their interactions with cells, biomolecules, and body tissues
List of Contributors
ix
Biography xiii
Preface xv
1 Introduction to Biomaterials and Devices for Bone Disorders
1(28)
S. Bose
D. Banerjee
A. Bandyopadhyay
1.1 Introduction
1(5)
1.2 Metallic Biomaterials
6(2)
1.3 Ceramic Biomaterials
8(4)
1.4 Polymeric Biomaterials
12(3)
1.5 Composite Biomaterials
15(1)
1.6 Additive Manufacturing (AM) of Biomaterials
16(2)
1.7 Biomaterials in Orthopedic Implants Devices
18(4)
1.8 Summary and Future Directions
22(7)
Acknowledgments
23(1)
References
23(6)
2 Bone Biology and Effects of Pharmaceutical Intervention on Bone Quality
29(54)
S.M. Ott
2.1 Bone Biology
29(23)
2.2 Pharmaceutical Intervention
52(18)
2.3 Summary
70(13)
References
70(13)
3 Bone Disorders
83(36)
J. Zang
L. Lu
M.J. Yaszemski
3.1 Introduction
83(2)
3.2 Metabolic Diseases
85(6)
3.3 Degenerative Disc Disease
91(4)
3.4 Osteoarthritis
95(3)
3.5 Fracture
98(2)
3.6 Bone Cancers
100(10)
3.7 Summary and Future Directions
110(9)
References
113(6)
4 Implants for Joint Replacement of the Hip and Knee
119(78)
J. Gallo
E. Gibon
S.B. Goodman
4.1 Historical Perspective
119(4)
4.2 Design and Material Issues, Clinical Outcome
123(13)
4.3 Current Critical Issues
136(41)
4.4 Future Trends and Next-Generation Devices
177(2)
4.5 Conclusion
179(18)
References
180(17)
5 Material and Mechanobiological Considerations for Bone Regeneration
197(68)
B.S. Klosterhoff
S. Nagaraja
J.J. Dedania
R.E. Guldberg
N.J. Willett
5.1 Introduction
197(3)
5.2 Physiology of Bone Regeneration
200(5)
5.3 Mechanical Properties of Materials for Bone Regeneration
205(20)
5.4 Cell-Level Mechanobiology of Bone Regeneration
225(10)
5.5 Tissue-Level Mechanobiology of Bone Regeneration
235(8)
5.6 Conclusions and Future Directions
243(22)
References
246(19)
6 Ceramics in Bone Grafts and Coated Implants
265(50)
M. Roy
A. Bandyopadhyay
S. Bose
6.1 Introduction
265(3)
6.2 Bioinert Ceramics
268(3)
6.3 Calcium Phosphates
271(6)
6.4 Ceramic Scaffolds
277(9)
6.5 Ceramics in Drug Delivery
286(4)
6.6 Bioceramic Coatings
290(10)
6.7 Bone Cement
300(6)
6.8 Bioglass for Bone Regeneration
306(2)
6.9 Summary and Future Directions
308(7)
References
309(6)
7 Ceramic Coatings in Load-Bearing Articulating Joint Implants
315(34)
V. Thomas
S.A. Catledge
P. Baker
G.P. Siegal
Y.K. Vohra
7.1 Introduction
315(4)
7.2 Knee Simulator Study Involving NSD-Coated Titanium Articulating Against Polyethylene
319(1)
7.3 Knee Simulator Study Involving Articulation of NSD on NSD
320(3)
7.4 Role of Ceramic-Boriding on CoCr for Subsequent CVD Diamond Deposition
323(6)
7.5 Biocompatibility and Osteo-Integration of Nanodiamond Coated Implant
329(1)
7.6 Nanodiamond (ND) Wear-Debris and Influence of Size and Concentration of Wear-Debris on Inflammation
330(6)
7.7 Summary and Future Perspectives
336(13)
Acknowledgments
342(1)
References
342(7)
8 Polymers and Composites for Orthopedic Applications
349(56)
S.V. Gohil
S. Suhail
J. Rose
T. Vella
L.S. Nair
8.1 Introduction
349(2)
8.2 Nondegradable Polymers and Composites for Orthopedic Applications
351(7)
8.3 Biodegradable Polymers and Composites for Orthopedic Applications
358(24)
8.4 Major Applications of Polymers and Their Composites for Orthopedic Applications
382(12)
8.5 Conclusions
394(11)
References
395(10)
9 Surface Modifications and Surface Characterization of Biomaterials Used in Bone Healing
405(48)
V.G. Varanasi
M.F. Velten
T. Odatsu
A. Ilyas
S.M. Iqbal
P.B. Aswath
9.1 Introduction
406(1)
9.2 Current Biomaterials for Bone Healing
407(12)
9.3 Use of Precision Manufacturing to Improve Biomaterials Fabrication and Biological Response
419(9)
9.4 Surface Characterization of Biomineral and Biomaterial Surfaces
428(14)
9.5 Current Challenges and Future Trends
442(4)
9.6 Summary
446(7)
References
447(6)
10 Predictive Methodologies for Design of Bone Tissue Engineering Scaffolds
453(40)
D.R. Katti
A. Sharma
K.S. Katti
10.1 Introduction
453(7)
10.2 In Vitro Mechanical Properties: Methods and Challenges
460(7)
10.3 Molecular Modeling for Design of Scaffolds
467(7)
10.4 Use of FE Methods for Predictive Capabilities of Scaffold Properties
474(2)
10.5 Degradation of Scaffolds in Cell Culture Media and Modeling Degradation
476(4)
10.6 Development of Multiscale Modeling Strategies for Scaffold Mechanics
480(4)
10.7 Summary
484(1)
10.8 Perspectives and Future Directions on the In Silico Approach to Scaffold Design
484(9)
References
485(8)
11 Ethical Issues in Biomaterials Research
493(12)
A. Kashi
S. Saha
11.1 Introduction
493(1)
11.2 Ethical Issues With Emerging Technologies
494(4)
11.3 Cost Versus Benefit Analysis
498(1)
11.4 Resource Allocation for Biomedical Research
499(1)
11.5 Ethical Issues With Authorship
499(1)
11.6 Discussion
500(1)
11.7 Current Challenges and Future Directions
501(1)
11.8 Guidelines for Ethical Practice in Biomaterials Research
501(4)
References
502(3)
12 Research on Bone Disorders---From Ideas to Clinical Use Product---The Path to Commercialization
505(12)
M. Kumar
12.1 Introduction
505(1)
12.2 What Is the Path to Commercialization?
506(1)
12.3 The Research Topic---The Big Idea. Is It Really That Big?
507(1)
12.4 The Big Idea---Short-Term and Near-Term Research
508(1)
12.5 Long-Term Research
509(1)
12.6 The Patent---A Step to Monetization of Research and the Big Idea
509(1)
12.7 Claims---Are They Broad Enough to Keep the Competition Out of This Space?
510(1)
12.8 Freedom to Practice/Operate---Can Some Other Patent Stop This Technology?
510(1)
12.9 What Are the Regulations Around This Big Idea Product?
511(3)
12.10 What Is the Cost of Making This Product?
514(1)
12.11 Conclusion
514(3)
13 Current Challenges and Future Needs in Biomaterials and Devices for Bone Disorders
517(9)
S. Bose
A. Bandyopadhyay
13.1 Introduction
517(3)
13.2 Current Challenges and Future Needs
520(6)
13.3 Summary
526(1)
Acknowledgments 526(1)
Index 527
Susmita Bose is a Professor in the School of Mechanical and Materials Engineering, an affiliate professor in the Department of Chemistry at Washington State University (WSU). In 2004, Dr. Bose received the prestigious Presidential Early Career Award for Scientist and Engineers (PECASE, the highest honor given to a young scientist by the US President at the White House) award from the National Science Foundation. Dr. Bose was named as a Kavli fellow” by the National Academy of Sciences. In 2009, she received the prestigious Schwartzwalder-Professional Achievement in Ceramic Engineering (PACE) Award, and in 2014 Richard M. Fulrath Award, which is an international award given to one academician in the US annually (below age 45), from the American Ceramic Society. Dr. Bose is editorial board member for several international journals, including Acta Biomaterialia, Journal of the American Ceramic Society, Journal of Materials Chemistry B, International Journal of Nanomedicine and Additive Manufacturing. Dr. Bose has published over 200 technical papers with ~ 5000 citations, h” index 40. Dr. Bose is a fellow of the American Institute for Medical and Biological Engineering (AIMBE) and the American Ceramic Society (ACerS). Prof. Bandyopadhyay is Herman and Brita Lindholm Endowed Chair Professor at the School of Mechanical and Materials Engineering, Washington State University (WSU), also a Fellow of the National Academy of Inventors (NAI), American Ceramic Society (ACerS), American Society for Materials (ASM International), American Institute for Medical and Biological Engineering (AIMBE) and American Association for the Advancement of Science (AAAS). He has published over 250 technical papers including over 170 journal papers. He holds 11 US patents and several patent applications are currently pending at the United States Patent and Trademark Office. He has edited 8 books.His research expertise lies with additive manufacturing of metallic and ceramic materials and their composites towards structural, bio- and piezoelectric materials.