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El. knyga: Medical Uses of Statistics

  • Formatas: 480 pages
  • Išleidimo metai: 20-May-2019
  • Leidėjas: CRC Press
  • Kalba: eng
  • ISBN-13: 9781482255621
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  • Formatas: 480 pages
  • Išleidimo metai: 20-May-2019
  • Leidėjas: CRC Press
  • Kalba: eng
  • ISBN-13: 9781482255621
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This work explains the purpose of statistical methods in medical studies and analyzes the statistical techniques used by clinical investigators, with special emphasis on studies published in "The New England Journal of Medicine". It clarifies fundamental concepts of statistical design and analysis, and facilitates the understanding of research results.
Contributing Authors xii
Preface xv
Preface to the First Edition xvi
Acknowledgments xix
Origins of
Chapters
xx
Introduction xxiii
SECTION I BROAD CONCEPTS AND ANALYTIC TECHNIQUES
Chapter 1 Statistical Concepts Fundamental to Investigations
5(22)
Lincoln R. Moses
Chapter 2 Some Uses of Statistical Thinking
27(18)
John C. Bailar
Chapter 3 Use of Statistical Analysis in the New England Journal of Medicine
45(16)
John D. Emerson
Graham A. Colditz
SECTION II DESIGN
Chapter 4 Designs for Experiments---Parallel Comparisons of Treatment
61(22)
Philip W. Lavori
Thomas A. Louis
John C. Bailar
Marcia Polansky
Chapter 5 Crossover and Self-Controlled Designs in Clinical Research
83(22)
Thomas A. Louis
Philip W. Lavori
John C. Bailar
Marcia Polansky
Chapter 6 Studies without Internal Controls
105(20)
John C. Bailar
Thomas A. Louis
Philip W. Lavori
Marcia Polansky
Chapter 7 The Series of Consecutive Cases as a Device for Assessing Outcomes of Interventions
125(16)
Lincoln E. Moses
Chapter 8 A Classification for Biomedical Research Reports
141(18)
John C. Bailar
Thomas A. Louis
Philip W. Lavori
Marcia Polansky
SECTION III ANALYSIS
Chapter 9 Decision Analysis
159(22)
Stephen G. Pauker
Jerome P. Kassirer
Chapter 10 P Values
181(20)
James H. Ware
Frederick Mosteller
Fernando Delgado
Christl Donnelly
Joseph A. Ingelfinger
Chapter 11 Simple Linear Regression in Medical Research
201(32)
Katherine Godfrey
Chapter 12 Comparing the Means of Several Groups
233(26)
Katherine Godfrey
Chapter 13 Analyzing Data from Ordered Categories
259(22)
Lincoln E. Moses
John D. Emerson
Hossein Hosseini
Chapter 14 Statistical Analysis of Survival Data
281(12)
Stephen Lagakos
Chapter 15 Contingency Tables in Medical Studies
293(20)
Daniel Zelterman
Thomas A. Louis
SECTION IV COMMUNICATING RESULTS
Chapter 16 Guidelines for Statistical Reporting in Articles of Medical Journals
313(20)
John C. Bailar
Frederick Mosteller
Chapter 17 Reporting on Methods in Clinical Trials
333(16)
Rebecca DerSimonian
L. Joseph Charette
Bucknam McPeek
Frederick Mosteller
Chapter 18 Statistical Consultation in Clinical Research: A Two-Way Street
349(8)
Lincoln E. Moses
Thomas A. Louis
Chapter 19 The Importance of Beta, the Type II Error, and Sample Size in the Design and Interpretation of the Randomized Controlled Trial: Survey of Two Sets of "Negative" Trials
357(18)
Jennie A. Freiman
Thomas C. Chalmers
Harry Smith Jr.
Roy R. Kuebler
Chapter 20 Writing about Numbers
375(18)
Frederick Mosteller
SECTION V REVIEWS AND META-STUDIES
Chapter 21 Medical Technology Assessment
393(20)
John C. Bailar
Frederick Mosteller
Chapter 22 Combining Results from Independent Investigations: Meta-Analysis in Clinical Research
413(14)
Katherine Taylor Halvorsen
Elisabeth Burdick
Graham A. Colditz
Howard S. Frazier
Frederick Mosteller
Chapter 23 Meta-Analyses of Randomized Control Trials: An Update of the Quality and Methodology
427(18)
Henry S. Sacks
Jayne Berrier
Dinah Reitman
Daniel Pagano
Thomas C. Chalmers
Index 445
JOHN C. BAILAR III FREDERICK MOSTELLER