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Methods in Aging Research [Kietas viršelis]

  • Formatas: Hardback, 720 pages, aukštis x plotis: 254x178 mm, weight: 1474 g, 16 Halftones, black and white; 16 Illustrations, black and white
  • Išleidimo metai: 29-Jun-1998
  • Leidėjas: CRC Press Inc
  • ISBN-10: 0849331129
  • ISBN-13: 9780849331121
Kitos knygos pagal šią temą:
  • Formatas: Hardback, 720 pages, aukštis x plotis: 254x178 mm, weight: 1474 g, 16 Halftones, black and white; 16 Illustrations, black and white
  • Išleidimo metai: 29-Jun-1998
  • Leidėjas: CRC Press Inc
  • ISBN-10: 0849331129
  • ISBN-13: 9780849331121
Kitos knygos pagal šią temą:
Gerontological research is currently of great interest due to ever-increasing longevity of human life spans. Created to provide researchers and scientists with the technical methods essential to their work, Methods in Aging Research is a practical bench-top guide for everyone who plans, designs, or conducts research in aging. It highlights experimental procedures that are key to the investigation of the biological aging phenomena.
Methods in Aging Research is a state-of-the-art reference that offers the most direct and clear cut descriptions available of methodological procedures used in aging research. Methods and protocols are critically evaluated and the advantages and disadvantages of each technique are explored. More than 70 expert contributors from around the world share their combined knowledge on a broad range of topics essential to everyone involved in cultivating and developing the gerontological research frontier.
Preface ix Section A: General Theoretical Approaches to Aging Research 3(70)
1. Population Study of Mortality and Longevity with Gompertzian Analysis 3(22) James R. Carey
2. Design of Cross-sectional, Longitudinal and Sequential Studies in Gerontology 25(18) Donald K. Ingram
3. Mathematical and Computational Tools for Gerontological Research 43(30) Tarynn M. Witten Section B: Experimental In Vitro Models in Aging Research 73(144)
4. Use of the Fibroblast Model 77(38) Vincent J. Cristofalo Maria Tresini Craig Volker Mary Kay Francis
5. Electrophysiological Assessment of the Aged Hippocampus In Vivo and In Vitro 115(30) Gregory M. Rose Karen L. Heman Gowri K. Pyapali Dennis A. Turner
6. Using Drosophila in Experimental Aging Research 145(22) Robert Arking R. C. Woodruff
7. Experimentation with Nematodes 167(24) Abraham Z. Reznick David Gershon
8. Experimentation with the Yeast Model 191(26) Sangkyu Kim Paul A. Kirchman Alberto Benguria S. Michal Jazwinski Section C: Vertebrate Models in Aging Research 217(54)
9. Long-Term Housing of Rodents Under Specific Pathogen-Free Barrier Conditions 217(20) Sherry M. Lewis Barbara L. Leard Angelo Turturro Ronald W. Hart
10. Choice of Rodent Model for Aging Research 237(12) Edward J. Masoro
11. Aging Experiments Using Nonhuman Primates 249(22) Ricki J. Colman Joseph W. Kemnitz Section D: Methods of Assessing Aging Processes 271(116)
12. Dietary Restriction 271(30) Helen A. Bertrand Jeremiah T. Herlihy Yuji Ikeno Byung P. Yu
13. Study Design for Nutritional Assessments in the Elderly 301(20) Helene Payette Yves Guigoz Bruno J. Vellas
14. Exercise 321(20) Li Li Ji Mitch Gore
15. Changes in Neurotransmitter Exocytosis: A Target for Regulation During Aging 341(20) Hoau-Yan Wang David L. Snyder Jay Roberts Eitan Friedman
16. Pathological Analysis in Aging Research 361(26) Gene B. Hubbard Yuji Ikeno Section E: Molecular and Evolutionary Probes of Senescence Alterations 387(128)
17. Transgenic Manipulation of the Mouse Genome 387(30) Christi A. Walter
18. Telomeres and Replicative Senescence 417(20) R. C. Allsopp S. S. Wang N. W. Kim C. B. Harley
19. Evolutionary Approaches to Probing Aging Mechanisms 437(16) Steven N. Austad Donna J. Holmes
20. Apoptosis and Programmed Cell Death 453(22) Ivor D. Bowen
21. Mitochondrial DNA Deletions 475(40) Maria N. Gadaleta Angela M. S. Lezza Palmiro Cantatore Section F: Techniques for Exploring Age-Related Intra- and Subcellular Changes 515(56)
22. Intracellular Signal Transduction Pathways Involved in Hepatocyte DNA Synthesis Following Growth Factor Stimulation 515(18) Yusen Liu Nikki J. Holbrook Gertrude C. Kokkonen Shoichi Kitano George S. Roth
23. Measurements of Mitochondrial Oxygen Radical Production 533(16) Gustavo Barja
24. Methods for the Study of Immune Cells in Aging 549(22) Gabriel Fernandes Section G: Techniques for Assessing Age-Related Oxidative Modification 571(114)
25. Lipid Peroxidation 571(36) Mitsuyoshi Matsuo Takao Kaneko
26. Measurement of Oxidative DNA Damage Using the Technique of Gas Chromatography-Mass Spectrometry 607(14) Miral Dizdaroglu
27. A Transgenic Mouse Model for Studing Mutations In Vivo 621(16) Jan Vijg Martijn E. T. Dolle Michael E. T. I. Boerrigter Jan A. Gossen
28. Protein Oxidationn 637(20) Pamela E. Starke-Reed
29. Glycation, Glycoxidation, and other-Maillard Reaction Products 657(28) Vincent M. Monnier John F. Fogarty Camille S. Monnier David R. Sell Index 685
Byung Pal Yu