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El. knyga: Methods of Clinical Epidemiology

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“Methods of Clinical Epidemiology” serves as a text on methods useful to clinical researchers. It provides a clear introduction to the common research methodology specific to clinical research for both students and researchers. This book sets out to fill the gap left by texts that concentrate on public health epidemiology and focuses on what is not covered well in such texts. The four sections cover methods that have not previously been brought together in one text and serves as a second level textbook of clinical epidemiology methodology. This book will be of use to postgraduate students in clinical epidemiology as well as clinical researchers at the start of their careers.

Recenzijos

This is an excellent book on statistical and mathematical epidemiology as it applies to diagnostics and treatment outcomes of medical conditions. Charts, tables, graphs, and equations are included throughout the discussions. This is a good book for PH students and researchers. (Joseph J. Grenier, Amazon.com, March, 2016)

Part I Clinical Agreement
1 Clinical Agreement in Qualitative Measurements
3(14)
Sophie Vanbelle
2 Clinical Agreement in Quantitative Measurements
17(12)
Abhaya Indrayan
3 Disagreement Plots and the Intraclass Correlation in Agreement Studies
29(10)
Suhail A.R. Doi
4 The Coefficient of Variation as an Index of Measurement Reliability
39(14)
Orit Shechtman
Part II Diagnostic Tests
5 Using and Interpreting Diagnostic Tests with Dichotomous or Polychotomous Results
53(14)
Cristian Baicus
6 Using and Interpreting Diagnostic Tests with Quantitative Results
67(12)
Suhail A.R. Doi
7 Sample Size Considerations for Diagnostic Tests
79(24)
Rajeev Kumar Malhotra
8 An Introduction to Diagnostic Meta-analysis
103(18)
Maria Nieves Plana
Victor Abraira
Javier Zamora
9 Health Technology Assessments of Diagnostic Tests
121(20)
Rosmin Esmail
Part III Modeling Binary and Time-to-Event Outcomes
10 Modelling Binary Outcomes
141(24)
Gail M. Williams
Robert Ware
11 Modelling Time-to-Event Data
165(22)
Gail M. Williams
Robert Ware
Part IV Systematic Reviews and Meta-analysis
12 Systematic Reviewing
187(26)
Justin Clark
13 Quality Assessment in Meta-analysis
213(16)
Maren Dreier
14 Meta-analysis I
229(24)
Suhail A.R. Doi
Jan J. Barendregt
15 Meta-analysis II
253(14)
Adedayo A. Onitilo
Suhail A.R. Doi
Jan J. Barendregt
Appendix: Stata codes 267(8)
Index 275
Suhail Doi is an Associate Professor of Clinical Epidemiology at the University of Queensland. He is involved in teaching, student supervision, curriculum development and research. He has published widely and his interest lies in research that addresses unanswered questions in patient care as well as questions related to methods of research design and analysis used in Medicine. Thus his research focuses on patient care topics such as epidemiology, prognosis and treatments of disease as well as methodology especially that related to meta-analysis. He is the co-author of the DoiThalib method for meta-analysis which was introduced in 2008 as an alternative to the random effects model.

Gail Williams is Professor of International Health Statistics at the University of Queensland. She has had long involvement in curriculum development and teaching in graduate programs in biostatistics and epidemiology, as well as consulting in clinical medicine and public health. Her specific areas of expertise include design and analysis of longitudinal studies, clinical and field intervention trials, survey design, and mathematical modelling. The focus of her applied research has been maternal and child health, a range of infectious diseases, and skin cancer. Her methodological areas of interest lie in statistical and mathematical modelling and approaches to dealing with attrition in longitudinal studies.