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xii | |
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1 Introduction to economic evaluation |
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1 | (18) |
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1 | (1) |
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1.2 Why is economic evaluation important? |
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2 | (1) |
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1.3 The features of economic evaluation |
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3 | (2) |
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1.4 Do all economic evaluations use the same techniques? |
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5 | (6) |
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1.5 Use of economic evaluation in health care decision-making |
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11 | (2) |
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13 | (6) |
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2 Making decisions in health care |
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19 | (22) |
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19 | (1) |
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2.2 Informing health care choices |
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19 | (3) |
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2.3 Requirements for economic evaluation |
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22 | (5) |
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2.4 What is the purpose of health care interventions? |
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27 | (10) |
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37 | (4) |
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3 Critical assessment of economic evaluation |
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41 | (36) |
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41 | (1) |
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3.2 Elements of a sound economic evaluation |
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41 | (20) |
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3.3 Reporting guidelines for economic evaluation |
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61 | (2) |
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3.4 Limitations of economic evaluation techniques |
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63 | (1) |
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64 | (1) |
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3.6 Critical appraisal of published articles |
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65 | (12) |
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4 Principles of economic evaluation |
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77 | (46) |
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4.1 Alternatives, costs, and benefits: some basics |
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77 | (2) |
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4.2 Making decisions about health care |
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79 | (4) |
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4.3 The cost-effectiveness threshold |
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83 | (15) |
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4.4 Making decisions with multiple alternatives |
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98 | (8) |
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4.5 Some methodological implications |
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106 | (10) |
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116 | (7) |
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5 Measuring and valuing effects: health gain |
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123 | (58) |
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123 | (1) |
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5.2 Using health effects in economic evaluation |
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124 | (9) |
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5.3 Measuring preferences for health states |
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133 | (3) |
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5.4 Methods for measuring preferences |
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136 | (8) |
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5.5 Multi-attribute health status classification systems with preference scores |
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144 | (18) |
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5.6 Mapping between non-preference-based measures of health and generic preference-based measures |
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162 | (2) |
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5.7 Whose values should be used to value health states? |
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164 | (2) |
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166 | (4) |
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170 | (11) |
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6 Measuring and valuing effects: consumption benefits of health care |
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181 | (38) |
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181 | (1) |
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6.2 Assigning money values to the outcomes of health care programmes |
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182 | (5) |
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6.3 What might we mean by willingness to pay (WTP)? |
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187 | (7) |
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6.4 Pragmatic measurement issues in willingness to pay (WTP) |
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194 | (3) |
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6.5 Exercise: designing a willingness-to-pay (WTP) survey for a new treatment for ovarian cancer |
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197 | (2) |
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6.6 Other stated preference approaches: discrete choice experiments (DCEs) |
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199 | (7) |
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6.7 Valuation of health effects for health policy decisions |
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206 | (5) |
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211 | (8) |
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219 | (48) |
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219 | (22) |
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7.2 Allowance for differential timing of costs (discounting and the annuitization of capital expenditures) |
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241 | (4) |
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245 | (5) |
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7.4 Exercise: costing alternative radiotherapy treatments |
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250 | (5) |
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255 | (12) |
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Annex 7.1 Tutorial on methods of measuring and valuing capital costs |
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258 | (4) |
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Annex 7.2 Discount tables |
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262 | (5) |
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8 Using clinical studies as vehicles for economic evaluation |
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267 | (44) |
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8.1 Introduction to vehicles for economic evaluation |
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267 | (1) |
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8.2 Alternative vehicles for economic evaluation |
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267 | (21) |
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8.3 Analytical issues with individual patient data |
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288 | (17) |
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305 | (1) |
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306 | (5) |
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9 Economic evaluation using decision-analytic modelling |
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311 | (42) |
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311 | (1) |
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9.2 The role of decision-analytic models for economic evaluation |
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312 | (11) |
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9.3 Key elements of decision-analytic modeling |
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323 | (2) |
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9.4 Stages in the development of a decision-analytic model |
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325 | (13) |
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9.5 Critical appraisal of decision-analytic models |
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338 | (1) |
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339 | (1) |
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9.7 Exercise: developing a decision-analytic model |
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339 | (14) |
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Annex 9.1 Checklist for assessing quality in decision-analytic models |
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345 | (8) |
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10 Identifying, synthesizing, and analysing evidence for economic evaluation |
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353 | (36) |
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10.1 Introduction to evidence in economic evaluation |
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353 | (1) |
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10.2 Defining relevant evidence |
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353 | (1) |
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10.3 Identifying and reviewing evidence |
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354 | (5) |
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10.4 Synthesizing evidence |
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359 | (11) |
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10.5 Estimating other parameters for economic evaluation |
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370 | (14) |
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384 | (1) |
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384 | (5) |
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11 Characterizing, reporting, and interpreting uncertainty |
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389 | (38) |
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389 | (3) |
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11.2 Characterizing uncertainty |
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392 | (17) |
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11.3 Is current evidence sufficient? |
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409 | (8) |
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11.4 Implications for approval and research decisions |
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417 | (10) |
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11.5 Uncertainty, heterogeneity, and individualized care |
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427 | (1) |
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427 | (1) |
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12 How to take matters further |
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427 | (4) |
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12.1 Taking matters further |
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427 | (1) |
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12.2 Further reading and key sources of literature |
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427 | (1) |
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12.3 Planning and undertaking an economic evaluation |
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427 | (1) |
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12.4 Expanding your network in economic evaluation |
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428 | (1) |
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12.5 Looking to the future |
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429 | (2) |
Author index |
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431 | (6) |
Subject index |
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437 | |