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Micro- and Nanoengineered Gum-Based Biomaterials for Drug Delivery and Biomedical Applications [Minkštas viršelis]

Edited by (Associate Professor, Department of Chemistry, Indira Gandhi National Tribal University, Amarkantak, Madhya Prades), Edited by (Assistant Professor, Department of Pharmaceutics, Gupta College of Technological Sciences, Asansol, West Bengal, India)
  • Formatas: Paperback / softback, 514 pages, aukštis x plotis: 235x191 mm, weight: 450 g, 80 illustrations (80 in full color); Illustrations
  • Serija: Micro & Nano Technologies
  • Išleidimo metai: 25-Jan-2022
  • Leidėjas: Elsevier - Health Sciences Division
  • ISBN-10: 0323909868
  • ISBN-13: 9780323909860
Kitos knygos pagal šią temą:
  • Formatas: Paperback / softback, 514 pages, aukštis x plotis: 235x191 mm, weight: 450 g, 80 illustrations (80 in full color); Illustrations
  • Serija: Micro & Nano Technologies
  • Išleidimo metai: 25-Jan-2022
  • Leidėjas: Elsevier - Health Sciences Division
  • ISBN-10: 0323909868
  • ISBN-13: 9780323909860
Kitos knygos pagal šią temą:

Micro- and Nanoengineered Gum-Based Biomaterials for Drug Delivery and Biomedical Applications focuses on micro- and nanotechnology in gums and biopolymers as drug and biomolecule carriers and their applications in biomedicine. Currently, natural gums and polymers are widely utilized as biocarrier systems, to deliver drugs and biomolecules to the target site, for prolonged release and the desired therapeutic effect. Natural gums and polymers are important because they are easily available from natural sources and are characteristically biodegradable, biocompatible, and nontoxic. Natural gums and polymers are also chemically modified with other polymers, in the presence of cross-linking agents, to develop scaffolds, matrices, composites, and interpenetrating polymer networks using micro- and nanotechnology. The book also discusses biological applications, such as gene delivery, cancer therapy, tissue engineering, bioimaging, and theranostics.

This book is an important reference source for biomaterials scientists, biomedical engineers, and pharmaceutical scientists, who are looking to increase their understanding of how micro- and nanoengineered biomaterials are being used to create more efficient gum-based drug delivery systems.

Contributors ix
Editors' biography xiii
Preface xv
1 Nanomedicine approaches and strategies for gum-based stealth nanocarriers
Nikhil R. Bali
Megha N. Karemore
Siddhesh S. Jadhav
Ruchika M. Bondre
Nikhil Y. Yenorkar
1.1 Introduction
1(2)
1.2 Need for stealth nanocarriers
3(1)
1.3 Hydrophilic polymers as shielding agent for nanocarriers
4(2)
1.4 Gum-based stealth nanocarriers: An alternative approach for transportation of payloads to targeted sites
6(18)
1.5 Concluding remarks
24(11)
References
25(10)
2 Micro- and nanoscale drug delivery systems based on xanthan gum hydrogels
Ljiljana Djekic
Ana Ciric
2.1 Introduction
35(3)
2.2 Homopolymeric XG-based hydrogels
38(1)
2.3 Copolymeric XG-based hydrogels
39(13)
2.4 XG-based nanocomposite hydrogels
52(9)
2.5 Drug delivery potential of xanthan gum hydrogels as nano- and microcarriers for different routes of administration
61(11)
2.6 Concluding remarks
72(5)
References
72(5)
3 Chitosan-based nanoengineered drug delivery system
Sreejan Manna
Aishik Banerjee
Sougata Jana
Manas Bhowmik
3.1 Introduction
77(2)
3.2 Drug delivery applications of chitosan-based nanoengineered systems
79(11)
3.3 Conclusions
90(8)
References
90(8)
4 Pectin-based micro- and nanomaterials in drug delivery
De-Qiang Li
Feng Xu
Jun Li
4.1 Introduction
98(1)
4.2 Properties of pectin
99(2)
4.3 Pectin extraction
101(3)
4.4 Modification of pectin
104(4)
4.5 Pectin in biomedical applications
108(2)
4.6 Pectin-based hybrid materials in drug delivery
110(5)
4.7 Pectin-based composite materials in drug delivery applications
115(4)
4.8 Conclusions
119(8)
References
119(8)
5 Gellan gum nanoparticles in drug delivery
Ana Leticia Rodrigues Costa
Lucimara Gaziolla de la Torre
5.1 Introduction
127(1)
5.2 Gellan gum
128(2)
5.3 Production and characterization of gellan gum nanoparticles
130(13)
5.4 Gellan gum nanoparticles (GG nanoparticles) in drug delivery
143(7)
5.5 Conclusions
150(7)
Acknowledgments
151(1)
References
151(6)
6 Gum kondagogu as a potential material for micro- and nanoparticulate drug delivery
Rimpy
Munish Ahuja
6.1 Introduction
157(3)
6.2 Modifications of gum kondagogu
160(4)
6.3 Applications of gum kondagogu as a microparticulate and nanoparticulate carrier
164(13)
6.4 Conclusions
177(6)
References
177(6)
7 Gum-based nanoparticles in cancer therapy
Maria John Newton Amaldoss
Reeta
7.1 Introduction
183(1)
7.2 Principal natural gums in pharmaceutical applications
184(6)
7.3 Method of preparation of GNPs
190(3)
7.4 Characterization techniques for GNPs
193(5)
7.5 General biomedical applications of gums
198(6)
7.6 Gum-based nanoparticles in cancer therapy
204(11)
7.7 Conclusions
215(12)
References
216(11)
8 Gum-based micro- and nanobiomaterials in gene delivery
M.R. Rekha
8.1 Introduction
227(1)
8.2 Classification
227(1)
8.3 Biomedical application of gums
228(1)
8.4 Nonviral gene delivery
228(1)
8.5 Natural gum-based gene delivery vectors
229(8)
8.6 Conclusions
237(4)
References
237(4)
9 Locust bean gum-based micro- and nanomaterials for biomedical applications
R.S. Soumya
K.G. Raghu
Annie Abraham
9.1 Introduction
241(2)
9.2 Locust bean gum
243(1)
9.3 Biodegradation of LBG
244(1)
9.4 Bioactivity of LBG
245(1)
9.5 Pharmaceutical applications of LBG
245(1)
9.6 LBG microparticles
246(1)
9.7 LBG nanoparticles
246(4)
9.8 Conclusions
250(5)
References
250(5)
10 Alginate microspheres: Synthesis and their biomedical applications
Nguyen Thi Thanh Uyen
Syazana Ahmad Zubir
Tuti Katrina Abdullah
Nurazreena Ahmad
10.1 Introduction
255(1)
10.2 Structure and physicochemical properties of alginates
256(7)
10.3 Fabrication of alginate microspheres
263(5)
10.4 Alginate microsphere and its biomedical applications
268(9)
10.5 Conclusions
277(8)
References
278(7)
11 Biomedical applications of cashew gum-based micro- and nanostructures
Gouranga Nandi
Subhankar Mukhopadhyay
11.1 Introduction
285(1)
11.2 Isolation and purification of cashew gum
286(2)
11.3 Chemical composition and molecular structure of cashew gum
288(1)
11.4 Physiochemical characteristics of cashew gum
289(1)
11.5 Chemical modifications of cashew gum
290(1)
11.6 Cashew gum-based microstructures
291(3)
11.7 Cashew gum-based nanostructures
294(5)
11.8 Conclusions
299(4)
References
299(4)
12 Dextran-based micro- and nanobiomaterials for drug delivery and biomedical applications
Yeliz Basaran Elalmis
Ecem Tiryaki
Burcu Karakuzu Ikizler
Sevil Yucel
12.1 Introduction
303(4)
12.2 Application of dextrans
307(1)
12.3 Dextran-based micro- and nanogels
308(7)
12.4 Dextran-based electrospun nanofibers
315(3)
12.5 Dextran-based micro- and nanoparticles
318(7)
12.6 Concluding remarks
325(8)
References
326(7)
13 Gum arabic-based nanocarriers for drug and bioactive compounds delivery
Neda Aliabbasi
Morteza Fathi
Zahra Emam-Djomeh
13.1 Introduction
333(1)
13.2 Safety of gum arabic
334(1)
13.3 Chemical composition and structure
334(1)
13.4 Gum arabic: An excellent polysaccharide for encapsulation of bioactive agents
335(1)
13.5 Different nanocarriers prepared with GA
335(2)
13.6 Application of GA nanocarriers for various food bioactive agents
337(4)
13.7 Conclusions and further remarks
341(6)
References
342(5)
14 Tamarind gum as a wall material in the microencapsulation of drugs and natural products
Erik Alpizar-Reyes
Stefani Cortes-Camargo
Angelica Roman-Guerrero
Cesar Perez-Alonso
14.1 Introduction
347(4)
14.2 Tamarind gum characterization
351(7)
14.3 Functional properties of tamarind gum
358(5)
14.4 Tamarind gum-based colloidal systems in food and pharmaceutical applications
363(8)
14.5 Tamarind gum in industrial applications
371(12)
References
376(7)
15 Tree gum-based nanostructures and their biomedical applications
K.P. Akshay Kumar
Rohith K. Ramakrishnan
Miroslav Cernik
Vinod V.T. Padil
15.1 Introduction
383(2)
15.2 Tree gum exudates---Structure and properties
385(2)
15.3 Nanoarchitectures based on tree gums
387(2)
15.4 Tree gum-based NPs for biomedical applications
389(2)
15.5 Tree gum composite nanofibers for biomedical applications
391(2)
15.6 Tree gum-based nanostructures for drug delivery
393(3)
15.7 Hydrogels/nanogels based on tree gums for biomedical applications
396(5)
15.8 Conclusions
401(8)
Acknowledgments
401(1)
References
401(8)
16 Application of micro- and nanoengineering tragacanth and its water-soluble derivative in drug delivery and tissue engineering
Azam Chahardoli
Nasim Jamshidi
Aliasghar Varvani
Yalda Shokoohinia
Ali Fattahi
16.1 Introduction
409(3)
16.2 Composition and chemical structure of TG
412(2)
16.3 Properties
414(1)
16.4 Characterization
415(1)
16.5 Chemical modification of TG
415(1)
16.6 Biomedical applications
416(35)
References
442(9)
17 Development of Persian gum-based micro- and nanocarriers for nutraceutical and drug delivery applications
Rassoul Kadkhodaee
Nassim Raoufi
17.1 Introduction
451(1)
17.2 Medicinal applications of Amygdalus scoparia
452(1)
17.3 Chemical composition, structure, and properties
453(2)
17.4 Improving solubility and functionality of PG
455(1)
17.5 Drug delivery systems
456(10)
17.6 Other biological applications of PG
466(1)
17.7 Concluding remarks and future trends
467(6)
References
467(6)
18 Guar gum-based hydrogel and hydrogel nanocomposites for biomedical applications
Chinmoy Baruah
Jayanta K. Sarmah
18.1 Introduction
473(1)
18.2 Chemistry of hydrogels
474(1)
18.3 Synthetic routes of hydrogel
475(3)
18.4 Polymers for hydrogel systems
478(1)
18.5 Chemistry of guar gum
479(1)
18.6 Applications of gg-based hydrogels
480(3)
18.7 Guar gum-based hydrogels
483(5)
18.8 Conclusions
488(1)
References 489(4)
Index 493
Dr. Sougata Jana is an Assistant Professor in the Department of Pharmaceutics at Gupta College of Technological Sciences, Asansol, India. His research focuses on the modification of synthetic and natural biopolymers, formulation development, such as oral drug delivery, transdermal drug delivery, preparation and characterization of drug-loaded microspheres, micro-particles, nanoparticles and gels, and development of interpenetrating networking systems for drug delivery. Dr. Subrata Jana is an Associate Professor in the Department of Chemistry at Indira Gandhi National Tribal University, Amarkantak, India. His research interests are molecular recognition and supramolecular chemistry, organic synthesis, medicinal chemistry, protein engineering, and enzyme catalysis.