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El. knyga: Microneedles

(Professor of Pharmaceutics, Touro University California, USA)
  • Formatas: EPUB+DRM
  • Išleidimo metai: 06-Feb-2022
  • Leidėjas: Academic Press Inc
  • Kalba: eng
  • ISBN-13: 9780323972345
Kitos knygos pagal šią temą:
MicroneedlesDidesnis paveikslėlis
  • Formatas: EPUB+DRM
  • Išleidimo metai: 06-Feb-2022
  • Leidėjas: Academic Press Inc
  • Kalba: eng
  • ISBN-13: 9780323972345
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Microneedles explores the design, fabrication and use of microneedles for drug and vaccine delivery. This book discusses the contemporary status of the field, describing several areas in detail, including the distinct types of microneedles (dissolving, solid, coted, hollow and hydrogel-forming). The anatomy of the eye is also described to facilitate an understanding of microneedle-assisted ocular drug delivery. Finally, the book provides a detailed discussion of microneedle use in the field of diagnostics, with a chapter dedicated to the mathematical modeling of microneedle-mediated drug delivery.

As microneedles can be used by research scientists in academia and in industry, this book will be ideal for regulatory scientists and graduate students who find the topic relevant to their area of study.

  • Provides information for the design and fabrication of microneedles
  • Discusses choice of materials, fabrication protocol, sterilization protocol and characterization
  • Supplies the most up-to-date research on all aspects of microneedles

Recenzijos

"This book discusses various aspects of microneedle technology, a novel drug delivery system,... [ and] provides an overview of the development of microneedle-based drug delivery systems.... [ R]eaders are expected to find it a handy reference.... In 13 chapters, the author presents the recent advancements in microneedle-based devices by discussing the selection of materials, fabrication techniques, sterilization methods, classification, and pharmaceutical application of microneedles.... This book provides basic microneedles principles and advances and briefly introduces the general fabrication strategies, which the audience will find as a handy reference...." --Rahmat M. Talukder, PhD, RPh(The University of Texas at Tyler)

Acknowledgments ix
1 Introduction
1(20)
Background
1(3)
Microneedle-assisted delivery of therapeutic agents
4(11)
References
15(6)
2 Fabrication of microneedles
21(28)
Introduction
21(2)
Recent advances in the fabrication of microneedles
23(15)
Industrial fabrication of microneedles
38(4)
References
42(7)
3 Dissolving microneedles
49(24)
Introduction
49(1)
Dissolving microneedles for drug delivery
50(18)
References
68(5)
4 Anatomy and physiology of the eye
73(20)
Introduction
73(1)
Structure and function of the human eye
74(14)
References
88(5)
5 Microneedle-assisted drug delivery to the eye
93(22)
Introduction
93(3)
Microneedle-mediated ocular drug delivery
96(15)
References
111(4)
6 Microneedles for diagnostic testing
115(24)
Introduction
115(4)
Microneedle-based diagnostics
119(16)
References
135(4)
7 Therapeutic drug monitoring with microneedles
139(8)
Introduction
139(3)
Microneedle-mediated therapeutic drug monitoring
142(3)
References
145(2)
8 Miscellaneous routes of microneedle-assisted drug delivery
147(14)
Microneedle-assisted vaccine delivery
147(6)
Diverse routes of microneedle-mediated drug delivery
153(5)
References
158(3)
9 Mathematical modeling of drug delivery from microneedles
161(22)
Introduction
161(1)
Microneedle-assisted drug delivery and mathematical models
162(18)
References
180(3)
10 Solid microneedles
183(24)
Skin anatomy and physiology
183(5)
Transdermal drug delivery with solid microneedles
188(13)
References
201(6)
11 Coated microneedles
207(14)
Introduction
207(1)
Drug delivery with coated microneedles
208(10)
References
218(3)
12 Hollow microneedles
221(12)
Introduction
221(1)
Skin delivery of drugs with hollow microneedles
222(8)
References
230(3)
13 Hydrogel-forming microneedles
233
Introduction
233(2)
Transdermal drug delivery from hydrogel-forming microneedles
235(9)
References
244
Dr. Ita holds a PhD in Pharmaceutics. His area of expertise is transdermal drug delivery. He has over 40 publications in this area and teaches Pharmaceutics to both first- and second year pharmacy students at the College of Pharmacy, Touro University, California. He joined the University in 2006 as an Assistant Professor and is now a Full Professor. He was awarded an ICRETT Fellowship by the International Union Against Cancer (IUCC).
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