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El. knyga: Mismatch: The lifestyle diseases timebomb

3.83/5 (97 ratings by Goodreads)
  • Formatas: PDF+DRM
  • Išleidimo metai: 29-Sep-2006
  • Leidėjas: Oxford University Press
  • Kalba: eng
  • ISBN-13: 9780191513121
  • Formatas: PDF+DRM
  • Išleidimo metai: 29-Sep-2006
  • Leidėjas: Oxford University Press
  • Kalba: eng
  • ISBN-13: 9780191513121

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Our bodies and body processes evolved to allow our ancestors the best chance of survival as hunter-gatherers in the Savannah. Our brains, on the other hand, have evolved intelligence, imagination, and foresight, allowing us to leave all other creatures behind, and develop complex societies, cultures, and lifestyles, far removed from those of our ancestors.
The development of a modern human in utero still reflects our past, and we have created a modern, artificial world that is out of tune with our evolved bodies. Could it be that this mismatch has led to the current deadly explosion in 'lifestyle' diseases such as diabetes and obesity, and will it lead to increasingly frequent epidemics? We appear unable to evolve out of this problem, and unwilling to return to a different way of life, so how can we understand and address this increasingly crucial challenge?
Gluckman and Hanson set out the case, examining issues that are at times controversial and speculative. Utilizing the latest research in epigenetics (that genes may be environmentally modified), they propose that intervention in early human development, alongside a better focus on the health of potential mothers, can make future generations better suited to the modern world.

Recenzijos

Thought-provoking...this book conveys admirably, for a non-specialist reader, the implications of an important idea. Michael Sargent, Nature (Books and Arts Review) Compelling book Laura Howes, Chemistry World Essential reading for anybody interested in the fascinating complexities of human biology...A most timely and innovative contribution to the popular debate about genes and the environment. Robert Winston, from the Foreword A fascinating and important journey through the development and evolution of human health. Lewis Wolpert Some possible solutions are suggested here, but for the most part Hanson and Gluckman just lay the cards out on the table for you to contemplate, which is refreshing. They offer a very humane insight that can help us all make sense of the modern world and our place in it. Margaret Bartlett, Health and Fitness

Introduction: Our Bodies and our World 1(16)
Part I. Match
Our Comfort Zone
17(32)
Where Have We Come From?
49(25)
When We Were Very Young
74(20)
Things Ain't What They Used to Be
94(30)
Constrained by our Pasts
124(13)
Part II. Mismatch
Coming of Age
137(21)
A Life of Luxury
158(20)
Four Score Years and Ten
178(16)
Match and Mismatch
194(18)
Epilogue 212(1)
Notes 213(54)
Acknowledgements 267(2)
Index 269