El. knyga: Molecular Basis of Cancer E-Book: The Molecular Basis of Cancer E-Book

Citing the last three decades as demonstrating a great acceleration in observations and discoveries that illuminate the genetic basis of cancer, as well as the study of malignancy transforming understanding of the molecular and genetic processes that regulate the growth and proliferation of normal cells, The Molecular Basis of Cancer describes the scientific foundation that will promote better understanding of the disease and its therapy. Mendelsohn, Gray, Howley, Israel, and Thompson, experts and educators, designed a sequence of sections and chapters that move the reader along from the basic genetic and molecular mechanisms of carcinogenesis to the molecular and biological features of cancer cell growth, then to sequencing technologies and bioformatics that support risk assessment and diagnostics, followed by a description of molecular and genetic abnormalities that promote common types of cancer, and, finally, to the molecular basis for new, targeted approaches to cancer therapy. There are 59 chapters divided into five parts: carcinogenesis and cancer genetics; cancer biology; molecular pathology and diagnostics; molecular pathogenesis and therapeutic targets for specific cancer; and molecular basis of cancer therapy. There are color and black-and-white figures, tables, and key references. Annotation ©2014 Ringgold, Inc., Portland, OR (protoview.com) The Molecular Basis of Cancer arms you with the latest knowledge and cutting-edge advances in the battle against cancer. This thoroughly revised, comprehensive oncology reference explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of this disease. A team of leading experts thoroughly explains the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Detailed descriptions of topics from molecular abnormalities in common cancers to new approaches for cancer therapy equip you to understand and apply the complexities of ongoing research in everyday clinical application. Effectively determine the course of malignancy and design appropriate treatment protocols by understanding the scientific underpinnings of cancer. Visually grasp and retain difficult concepts easily thanks to a user-friendly format with abundant full-color figures. Find critical information quickly with chapters following a logical sequence that moves from pathogenesis to therapy. Stay current with the latest discoveries in molecular and genomic research. Sweeping revisions throughout include eight brand-new chapters on: Tumor Suppressor Genes; Inflammation and Cancer; Cancer Systems Biology: The Future; Biomarkers Assessing Risk of Cancer; Understanding and Using Information About Cancer Genomes; The Technology of Analyzing Nucleic Acids in Cancer; Molecular Abnormalities in Kidney Cancer; and Molecular Pathology. Access the entire text and illustrations online, fully searchable, at Expert Consult.