| Contributors |
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xv | |
| Preface to the First Edition |
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xxiii | |
| Preface to the Second Edition |
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xxv | |
| Preface to the Third Edition |
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xxvii | |
| Preface to the Fourth Edition |
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xxix | |
| Historical Aspects of Mucosal Immunology |
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xxxi | |
| Jiri Mestecky, Jerry R. McGhee, John Bienenstock, Michael E. Lamm, Warren Strober, John J. Cebra, Lloyd Mayer, Pearay L. Ogra, Michael W. Russell |
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SECTION A Development and Organization of the Mucosal Immune System |
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1 Overview: The Mucosal Immune System |
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3 | (6) |
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2 Development and Physiology of the Intestinal Mucosal Defense |
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9 | (22) |
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3 Development of Gut-Associated Lymphoid Tissues |
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31 | (12) |
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4 Structure, Organization, and Development of the Mucosal Immune System of the Respiratory Tract |
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43 | (20) |
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5 The Mucosal Microbiome: Imprinting the Immune System of the Intestinal Tract |
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63 | (16) |
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6 The Microbiome at Other Mucosal Sites |
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79 | (16) |
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7 Endogenous Microbiota of the Genitourinary Tract |
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95 | (14) |
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8 Gnotobiology and the Study of Complex Interactions between the Intestinal Microbiota, Probiotics, and the Host |
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109 | (26) |
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Helena Tlaskalova-Hogenova |
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9 Mucosal Immunity in Invertebrates |
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135 | (10) |
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10 Comparative Phylogeny of the Mucosa-Associated Lymphoid Tissue |
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145 | (16) |
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11 Ontogeny of Mucosal Immunity and Aging |
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161 | (26) |
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12 Epithelial Cells: Structure, Transport, and Barrier Function |
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187 | (24) |
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13 M Cells: Specialized Antigen Sampling Cells in the Follicle-Associated Epithelium |
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211 | (20) |
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231 | (20) |
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15 Innate Humoral Defense Factors |
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251 | (20) |
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16 Defensins in Enteric Mucosal Immunity |
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271 | (16) |
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17 Mucosal Immunoglobulins |
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287 | (38) |
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18 Phylogeny and Comparative Physiology of Mucosal Immunoglobulins |
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325 | (24) |
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19 Immunoglobulin Transport and Immunoglobulin Receptors |
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349 | (60) |
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20 Fc Receptors in Mucosal Immunology |
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409 | (20) |
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21 Biological Activities of IgA |
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429 | (26) |
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22 Microbial Evasion of IgA Functions |
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455 | (16) |
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23 The Regulation of IgA Production |
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471 | (16) |
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SECTION B Inductive and Effector Cells and Tissues of the Mucosal Immune System |
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24 Overview: Inductive and Effector Cells and Tissues of the Mucosal Immune System |
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487 | (2) |
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25 Mucosal Dendritic Cells: Origins, Subsets, and Biology |
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489 | (54) |
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26 Mucosal Macrophages in Defense and Regulation |
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543 | (14) |
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27 Role of Epithelial Cells in Antigen Presentation |
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557 | (14) |
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28 Microbial Sensing and Regulation of Mucosal Immune Responses by Intestinal Epithelial Cells |
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571 | (20) |
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29 Epithelial Cell Regulation of Immune Responses in the Lung |
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591 | (14) |
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30 Signaling Mechanisms Regulating Innate Immune Responses |
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605 | (18) |
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31 The Mucosal B Cell System |
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623 | (60) |
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32 Regulation and Function of Mucosal IgA and IgD |
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683 | (18) |
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33 Mucosal B Cell Differentiation and Regulation |
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701 | (20) |
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34 Effector CD4+ T Cells in the Intestines |
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721 | (12) |
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35 Intraepithelial TCRαβ T Cells in Health and Disease |
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733 | (16) |
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36 Mucosal-Resident T Lymphocytes with Invariant Antigen Receptors |
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749 | (16) |
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37 Mucosal T Cell Receptor γδ Intraepithelial T Cells |
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765 | (12) |
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38 Intestinal Regulatory CD4+ T Cells |
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777 | (10) |
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39 Effector Cells of the Mucosal Immune System: Innate Lymphoid Cells |
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787 | (18) |
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40 Lymphocyte Trafficking to Mucosal Tissues |
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805 | (26) |
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41 Mechanisms of Oral Tolerance to Soluble Protein Antigens |
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831 | (18) |
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42 Gut Microbiota and Intestinal Adaptive Immunity |
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849 | (10) |
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43 Mast Cells, Basophils and Mucosal Immunity |
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859 | (24) |
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883 | (32) |
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915 | (14) |
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46 Neuronal Regulation of Mucosal Immune Responses |
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929 | (16) |
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SECTION C Mucosal Immunity and Infections |
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47 Overview: Mucosal Immunity and Infections |
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945 | (4) |
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48 Bacterial Adhesion to Intestinal Mucosa |
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949 | (6) |
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Arlette Darfeuille-Michaud |
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49 Bacterial Interactions with Mucosal Epithelial Cells |
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955 | (20) |
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50 Discriminating Pathogens from Commensals at Mucosal Surfaces |
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975 | (10) |
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51 Helicobacter pylori Infection of the Gastric Mucosa |
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985 | (18) |
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52 Innate Lymphoid Cells in Mucosal Homeostasis, Infections, Autoimmune Disorders, and Tumors |
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1003 | (10) |
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53 Virus Infection of Airway Epithelial Cells |
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1013 | (10) |
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54 Parasitic Infection of the Mucosal Surfaces |
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1023 | (16) |
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SECTION D Mucosal Vaccines |
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55 Mucosal Vaccines: An Overview |
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1039 | (8) |
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56 Vaccines against Bacterial Enteric Infections |
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1047 | (36) |
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57 Acute Gastroenteritis Viruses |
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1083 | (22) |
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58 Respiratory Bacterial Vaccines |
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1105 | (24) |
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59 Respiratory Virus Vaccines |
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1129 | (42) |
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60 Mucosal Immunity and Vaccines Against Simian Immunodeficiency Virus and Human Immunodeficiency Virus |
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1171 | (12) |
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61 Mucosal Adjuvants: New Developments and Challenges |
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1183 | (18) |
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62 Use of CpG Oligonucleotides as Mucosal Adjuvants |
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1201 | (10) |
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63 Antigen Delivery Systems I: Nonliving Microparticles, Liposomes, and Immune-Stimulating Complexes (ISCOMs) |
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1211 | (22) |
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64 Antigen Delivery System II: Development of Live Attenuated Bacterial Vectors |
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1233 | (38) |
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65 Mucosal Vaccines from Plant Biotechnology |
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1271 | (20) |
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66 Filling the Immunological Gap: Recombinant Viral Vectors for Mucosal Vaccines |
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1291 | (16) |
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67 DNA Vaccines for the Induction of Immune Responses in Mucosal Tissues |
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1307 | (30) |
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68 Mucosal Veterinary Vaccines: Comparative Vaccinology |
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1337 | (26) |
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Gourapura J. Renukaradhya |
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69 Mucosal Vaccines for Dental Diseases |
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1363 | (28) |
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70 Parenteral Immunization and Protection from Mucosal Infection |
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1391 | (12) |
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71 Passive Immunization: Toward Magic Bullets |
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1403 | (34) |
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SECTION E Immunodeficiency |
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72 Overview: Mucosal Immunity and Immunodeficiency |
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1437 | (4) |
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73 IgA Deficiency and Other Immunodeficiencies Causing Mucosal Immunity Dysfunction |
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1441 | (20) |
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74 Malnutrition, Immunodeficiency, and Mucosal Infection |
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1461 | (20) |
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Susanna Cunningham-Rundles |
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75 Human/Simian Immunodeficiency Virus Transmission and Infection at Mucosal Sites |
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1481 | (12) |
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76 Simian Immunodeficiency Virus Infection and Mucosal Immunity |
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1493 | (28) |
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77 Microbial Translocation and the Effects of HIV/SIV Infection on Mucosal Barrier Function |
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1521 | (12) |
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SECTION F Gastrointestinal and Hepatic Diseases |
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78 Overview: Gastrointestinal and Hepatic Diseases |
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1533 | (4) |
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79 Experimental Models of Gastrointestinal Inflammatory Diseases |
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1537 | (14) |
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80 Immunopathology of Celiac Disease |
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1551 | (22) |
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1573 | (40) |
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1613 | (24) |
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83 Allergic Inflammatory Diseases of the Gastrointestinal Tract |
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1637 | (12) |
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84 IgE-Mediated Food Allergy |
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1649 | (12) |
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85 Autoimmune Enteropathy and IPEX Syndrome |
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1661 | (6) |
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86 Protein-Losing Enteropathies |
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1667 | (28) |
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87 Liver and the Biliary Tract |
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1695 | (24) |
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88 Immune Mechanisms of Pancreatitis |
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1719 | (18) |
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89 Gastrointestinal Lymphoma |
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1737 | (12) |
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90 Systemic Manifestations of Mucosal Diseases: Trafficking of Gut Immune Cells to Joint, Liver, and Pancreas |
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1749 | (12) |
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91 Intestinal Inflammation and Cancer of the Gastrointestinal Tract |
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1761 | (18) |
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SECTION G Respiratory Tract |
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92 Overview: Mucosal Immunity and Disease of the Respiratory Tract |
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1779 | (4) |
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93 Mechanisms of Experimental Mouse Models of Airway Hyperresponsiveness |
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1783 | (22) |
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94 The Mucosal Immune Response to Respiratory Viruses |
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1805 | (12) |
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95 Local Immune Responses in Tuberculosis |
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1817 | (16) |
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96 Asthma: Clinical Aspects and Mucosal Immunology |
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1833 | (24) |
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97 Chronic Obstructive Pulmonary Disease |
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1857 | (12) |
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SECTION H Oral Cavity, Upper Airways, and Head and Neck |
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98 Mucosal Immunity in the Oral Cavity, Upper Respiratory Tract, and Adjacent Areas: An Overview |
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1869 | (4) |
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99 Ocular Mucosal Immunity |
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1873 | (26) |
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100 Nasal Immunity, Rhinitis, and Rhinosinusitis |
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1899 | (24) |
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101 Middle Ear and Eustachian Tube Mucosal Immunology |
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1923 | (20) |
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102 Immunology of Diseases of the Oral Cavity |
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1943 | (42) |
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103 Immunobiology of the Tonsils and Adenoids |
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1985 | (34) |
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SECTION I Genitourinary Tract and Mammary Gland |
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104 Urogenital Tract and Mammary Gland: Overview |
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2019 | (4) |
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105 IgA Nephropathy and Related Diseases |
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2023 | (16) |
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106 Urinary Tract Infections and the Mucosal Immune System |
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2039 | (20) |
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107 Animal Models of Immunity to Female Genital Tract Infections and Vaccine Development |
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2059 | (38) |
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108 Mucosal Immunity in the Human Female Reproductive Tract |
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2097 | (28) |
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109 Human Male Genital Tract Immunity |
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2125 | (16) |
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110 Endocrine Regulation of the Mucosal Immune System in the Female Reproductive Tract |
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2141 | (16) |
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111 Immunologically Mediated Male and Female Reproductive Failure |
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2157 | (26) |
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112 Immunity to Sexually Transmitted Infections |
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2183 | (32) |
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113 Maternal Genital Tract Infection: Implications for the Fetus and Newborn |
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2215 | (16) |
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114 Immunity at the Maternal-Fetal Interface |
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2231 | (20) |
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115 Amniotic Fluid and the Fetal Mucosal Immune System |
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2251 | (18) |
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116 The Mammary Gland in Mucosal and Regional Immunity |
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2269 | (38) |
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117 Human Milk: Its Components and Their Immunobiologic Functions |
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2307 | (38) |
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Appendix I Collection and Processing of Human Mucosal Secretions |
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2345 | (10) |
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Appendix II Collection and Processing of External Secretions and Tissues of Mouse Origin |
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2355 | (14) |
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Appendix III Collection, Handling, and Analysis of Specimens for Studies of Mucosal Immunity in Animals of Veterinary Importance |
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2369 | (24) |
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| Index |
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2393 | |
Daugiau apie elektronines knygas