List of Figures |
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xi | |
List of Tables |
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xiii | |
Preface |
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xv | |
1 Introduction |
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1 | (26) |
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1.1 Multiple Extreme Values |
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2 | (4) |
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1.1.1 Evaluating the Risk of Multiple Disasters |
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2 | (3) |
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1.1.2 Multivariate Cumulative Distributions |
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5 | (1) |
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1.2 Minimum Effective Dose |
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6 | (7) |
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1.2.1 Minimum Effective Dose of MOTRIN |
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6 | (4) |
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1.2.2 Minimum Effective Dose without Normality |
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10 | (1) |
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1.2.3 Inequality Methods for Behren-Fisher Problem |
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11 | (1) |
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1.2.4 Adjusting Multiplicity for Two or More Substitutable Endpoints |
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12 | (1) |
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13 | (5) |
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13 | (2) |
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15 | (3) |
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1.4 Education Reform and Theoretical Windows |
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18 | (4) |
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1.4.1 Learning Outcomes of Different Pedagogies |
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19 | (1) |
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1.4.2 Therapeutic Windows of a Drug |
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20 | (2) |
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1.5 Ruin Probability and Multiple Premiums |
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22 | (2) |
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1.6 Martingale Inequality and Asset Portfolio |
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24 | (3) |
2 Fundamentals |
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27 | (56) |
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2.1 Univariate Bonferroni-type Bounds |
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30 | (11) |
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2.1.1 Linear Combination Bounds |
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30 | (5) |
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2.1.2 Non-linear Combination Bounds |
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35 | (6) |
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2.2 Univariate Optimality |
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41 | (18) |
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59 | (15) |
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2.3.1 Complete Bonferroni Summations |
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59 | (2) |
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2.3.2 Partial Bonferroni Summations |
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61 | (3) |
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2.3.3 Decomposition of Bonferroni Summations |
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64 | (3) |
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2.3.4 Classical Bonferroni Bounds in a Multivariate Setting |
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67 | (7) |
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2.4 Multivariate Optimality |
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74 | (9) |
3 Multivariate Indicator Functions |
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83 | (28) |
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3.1 Method of Indicator Functions |
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83 | (6) |
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3.2 Moments of Bivariate Indicator Functions |
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89 | (10) |
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3.2.1 Bounds for Joint Probability of Exactly r Occurrences |
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89 | (6) |
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3.2.2 Bounds for Joint Probability of at Least r Occurrences |
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95 | (4) |
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3.3 Factorization of Indicator Functions |
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99 | (6) |
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3.4 A Paradox on Factorization and Binomial Moments |
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105 | (6) |
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3.4.1 Upper Bound Inconsistency |
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105 | (5) |
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3.4.2 Lower Bound Inconsistency |
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110 | (1) |
4 Multivariate Linear Programming Framework |
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111 | (32) |
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4.1 Linear Programming Upper Bounds |
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112 | (11) |
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4.1.1 Matrix Expression of Upper Frechet Optimality |
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113 | (1) |
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4.1.2 Target Function of Linear Programming |
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114 | (2) |
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4.1.3 Linear Programming Constraints |
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116 | (3) |
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4.1.4 Duality Theorem and Existence of Optimality |
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119 | (4) |
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4.2 Linear Programming Lower Bounds |
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123 | (20) |
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4.2.1 Inconsistency of Linear Programming Lower Bounds |
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124 | (5) |
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4.2.2 Feasible Linear Programming Lower Bounds |
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129 | (2) |
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4.2.3 A Perturbation Device in Linear Programming Optimization |
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131 | (3) |
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4.2.4 An Iteration Process in Linear Programming Optimization |
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134 | (9) |
5 Bivariate Upper Bounds |
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143 | (24) |
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5.1 Bivariate Factorized Upper Bounds |
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143 | (4) |
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5.2 Bivariate High-degree Upper Bounds |
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147 | (3) |
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5.3 Bivariate Optimal Upper Bounds |
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150 | (10) |
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5.3.1 Linear Optimal Upper Bounds |
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150 | (5) |
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5.3.2 Bivariate Frechet Optimal Upper Bounds |
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155 | (5) |
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5.4 Applications in Multiple Testing |
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160 | (7) |
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5.4.1 Bonferroni Procedure |
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161 | (1) |
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5.4.2 Holm Step-down Procedure |
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162 | (1) |
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5.4.3 Improved Holm Procedure |
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163 | (4) |
6 Multivariate and Hybrid Upper Bounds |
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167 | (26) |
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6.1 High Dimension Upper Bounds |
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167 | (10) |
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177 | (7) |
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6.3 Applications in Successive Comparisons |
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184 | (9) |
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186 | (1) |
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6.3.2 Unequal Variances, Behrens-Fisher Problem |
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186 | (7) |
7 Bivariate Lower Bounds |
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193 | (30) |
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7.1 Bivariate Factorized Lower Bounds |
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193 | (10) |
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7.2 Bivariate High-degree Lower Bounds |
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203 | (1) |
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7.3 Bivariate Optimal Factorized Bounds |
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204 | (4) |
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7.4 Bivariate Optimal Algorithm Bounds |
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208 | (13) |
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7.5 Applications in Seasonal Trend Analysis |
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221 | (2) |
8 Multivariate and Hybrid Lower Bounds |
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223 | (28) |
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8.1 High Dimension Lower Bounds |
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223 | (5) |
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228 | (21) |
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8.2.1 Setting of Hybrid Lower Bounds |
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229 | (5) |
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8.2.2 Main Results of Hybrid Lower Bounds |
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234 | (10) |
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8.2.3 Examples of Hybrid Lower Bounds |
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244 | (5) |
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8.3 Applications in Outlier Detection |
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249 | (2) |
9 Case Studies |
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251 | (18) |
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9.1 Molecular Cancer Therapy |
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251 | (2) |
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253 | (3) |
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9.3 Minimum Effective Dose with Heteroscedasticity |
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256 | (2) |
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9.4 Simultaneous Inference with Binary Data |
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258 | (3) |
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9.5 Post-thrombotic Syndrome and Rang Regression |
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261 | (3) |
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9.6 Vascular Risk Assessment |
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264 | (1) |
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265 | (4) |
Bibliography |
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269 | (14) |
Index |
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283 | |