The advent of molecular genetics has been a revolutionary force in the advances in knowledge of the cause and treatment of neuromuscular diseases. It has led to new approaches in therapy, new concepts in diagnosis, and has opened up the fascinating world of mitochondrial diseases. The reflection of these advancements forms the basis of this volume on Myopathies. Advancements in molecular cell biology have led to new concepts of transmitters, receptors, ion channels, and surface membranes. Sweeping changes in immunology, clarifying the role of T and B cells, and the improved understanding of myasthenia, are also important advancements reflected in the book. Pointing to a future where the linking of molecular biology data to the clinical syndromes - and thereby to the development of rational therapy is achieved, this present volume is an excellent reflection of the state of affairs in 1992.
