Presents nanobiotechnology in drug delivery and disease management
Featuring contributions from noted experts in the field, this book highlights recent advances in the nano-based drug delivery systems. It also covers the diagnosis and role of various nanomaterials in the management of infectious diseases and non-infectious disorders, such as cancers and other malignancies and their role in future medicine.
Nanobiotechnology in Diagnosis, Drug Delivery and Treatment starts by introducing how nanotechnology has revolutionized drug delivery, diagnosis, and treatments of diseases. It then focuses on the role of various nanocomposites in diagnosis, drug delivery, and treatment of diseases like cancer, Alzheimer's disease, diabetes, and many others. Next, it discusses the application of a variety of nanomaterials in the diagnosis and management of gastrointestinal tract disorders. The book explains the concept of nanotheranostics in detail and its role in effective monitoring of drug response, targeted drug delivery, enhanced drug accumulation in the target tissues, sustained as well as triggered release of drugs, and reduction in adverse effects. Other chapters cover aptamer-incorporated nanoparticle systems; magnetic nanoparticles; theranostics and vaccines; toxicological concerns of nanomaterials used in nanomedicine; and more.
- Provides a concise overview of state-of-the-art nanomaterials and their application like drug delivery in infectious diseases and non-infectious disorders
- Highlights recent advances in the nano-based drug delivery systems and role of various nanomaterials
- Introduces nano-based sensors which detect various pathogens
- Covers the use of nanodevices in diagnostics and theranostics
Nanobiotechnology in Diagnosis, Drug Delivery and Treatment is an ideal book for researchers and scientists working in various disciplines such as microbiology, biotechnology, nanotechnology, pharmaceutical biotechnology, pharmacology, pharmaceutics, and nanomedicine.
List of Contributors vii
Preface xi
1 Nanotechnology: A New Era in the Revolution of Drug Delivery, Diagnosis,
and Treatment of Diseases 1
Avinash P. Ingle, Patrycja Goliska, Alka Yadav, Mehdi Razzaghi-Abyaneh,
Mrunali Patel, Rashmin Patel, Yulia Plekhanova, Anatoly Reshetilov, and
Mahendra Rai
2 Selenium Nanocomposites in Diagnosis, Drug Delivery, and Treatment 25
Irina A. Shurygina and Michael G. Shurygin
3 Emerging Applications of Nanomaterials in the Diagnosis and Treatment of
Gastrointestinal Disorders 47
Patrycja Goliska and Magdalena Wypij
4 Nanotheranostics: Novel Materials for Targeted Therapy and Diagnosis 63
Sougata Ghosh and Rohini Kitture
5 Aptamer-Incorporated Nanoparticle Systems for Drug Delivery 95
Fahimeh Charbgoo, Seyed Mohammad Taghdisi, Rezvan Yazdian-Robati, Khalil
Abnous, Mohammad Ramezani, and Mona Alibolandi
6 Application of Nanotechnology in Transdermal Drug Delivery 113
Dilesh Jagdish Singhavi and Shagufta Khan
7 Superparamagnetic Iron Oxide Nanoparticle-Based Drug Delivery in Cancer
Therapeutics 129
Dipak Maity, Atul Sudame, and Ganeshlenin Kandasamy
8 Virus-Like Nanoparticle-Mediated Delivery of Cancer Therapeutics 153
Yasser Shahzad, Abid Mehmood Yousaf, Talib Hussain, and Syed A.A. Rizvi
9 Magnetic Nanoparticles: An Emergent Platform for Future Cancer
Theranostics 171
Parinaz Nezhad-Mokhtari, Fatemeh Salahpour-Anarjan, Armin Rezanezhad, and
Abolfazl Akbarzadeh
10 Chitosan Nanoparticles: A Novel Antimicrobial Agent 197
Divya Koilparambil, Sherin Varghese, and Jisha Manakulam Shaikmoideen
11 Sulfur Nanoparticles: Biosynthesis, Antibacterial Applications, and Their
Mechanism of Action 217
Priti Paralikar and Mahendra Rai
12 Role of Nanotechnology in the Management of Indoor Fungi 229
Erasmo Gįmez-Espinosa, Leyanet Barberia-Roque, and Natalia Bellotti
13 Nanotechnology for Antifungal Therapy 259
Jacqueline Teixeira da Silva and Andre Correa Amaral
14 Chitosan Conjugate of Biogenic Silver Nanoparticles: A Promising Drug
Formulation with Antimicrobial and Anticancer Activities 273
Smitha Vijayan and Jisha Manakulam Shaikmoideen
15 Leishmaniasis: Where Infection and Nanoparticles Meet 295
Mohammad Imani and Azam Dehghan
16 Theranostics and Vaccines: Current Status and Future Expectations 359
Thais Francine Ribeiro Alves, Fernando Batain, Cecķlia Torqueti de Barros,
Kessie Marie Moura Crescencio, Venāncio Alves do Amaral, Mariana Silveira de
Alcāntara Chaud, Décio Luķs Portella, and Marco Vinķcius Chaud
17 Toxicological Concerns of Nanomaterials Used in Biomedical Applications
375
Avinash P. Ingle, Indarchand Gupta, and Mahendra Rai
Index 399
MAHENDRA RAI, PHD, has more than 35 years of teaching and research experience and has spent the last 13 years working in the area of nanotechnology. His research interests include the application of nanobiotechnology in various sectors like medicine and agriculture. He has published more than 400 research publications and edited/authored more than 50 books.
MEHDI RAZZAGHI-ABYANEH, PHD, has more than 20 years of teaching and research experience. He has published over 100 papers in international journals, 10 books, and a number of book chapters. The major research interest fields of Dr. Razzaghi-Abyaneh include nano-mycotoxicology, mycotoxins, nanotechnology, and nanomedicine.
AVINASH P. INGLE, PHD, has more than 10 years of research experience in the field of nanotechnology. He has more than 65 research publications, 40 book chapters, and 4 books to his credit. Currently, Dr. Ingle is working as post-doctoral fellow and his research interest include nanobiotechnology, nanotoxicology, and nanomedicine.
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