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El. knyga: Nanopathology: The Health Impact of Nanoparticles

  • Formatas: 312 pages
  • Išleidimo metai: 19-Apr-2016
  • Leidėjas: Pan Stanford Publishing Pte Ltd
  • ISBN-13: 9789814241151
Kitos knygos pagal šią temą:
  • Formatas: 312 pages
  • Išleidimo metai: 19-Apr-2016
  • Leidėjas: Pan Stanford Publishing Pte Ltd
  • ISBN-13: 9789814241151
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Enormous funds are currently being invested in nanotechnology, yet very little is known about how its products and by-products can interfere with both end users and people involved in their manufacture. Similar scenarios are already widely known in the history of science, such as the exploitation of radioactivity or the controversial issue of genetically modified organisms. As nanoparticles are more or less voluntarily produced, they are almost uncontrollably disseminated in the environment and in organisms and thus constitute a growing concern. By describing the impact of nanoparticles (and microparticles) on human and animal health, this book offers the first criteria for preventing potential problems deriving from these particles.
Acknowledgements vii
Preface ix
1. How the Whole Thing Began or the Logic Path Towards a Discovery 1
1.1 Introduction
6
1.2 Bibliography
10
2. In-vitro and in-vivo Biological Behaviour of Micro and Nanoparticles 11
2.1 Introduction
11
2.2 Nanoparticles and medical devices
13
2.2.1 Dentistry
13
2.2.2 Orthopaedics
14
2.2.3 Nanostructured surfaces
16
2.2.4 Drug delivery
17
2.2.5 Nanomedicine
19
2.3 The results of the nanopathology project
22
2.3.1 In-vivo experiments
28
2.4 Bibliography
33
3. Clinical Cases: Lung, Blood, Liver, Kidney, Digestive System, Vessels, Sperm 39
3.1 Introduction
39
3.2 Lung
42
3.3 Blood
70
3.4 Liver
80
3.5 Kidney and adrenal gland
95
3.6 Digestive system
102
3.7 Vessels
114
3.8 Sperm
115
3.9 A few considerations on reproduction
121
3.10 Bibliography
131
4. Six "Detective Stories" 135
4.1 The 1st case
135
4.2 The 2nd case
142
4.3 The 3rd case
145
4.4 The 4th case
148
4.5 The 5th case
152
4.6 The 6th case
155
5. War and Nanoparticles 161
5.1 Civilians living around a firing ground
198
5.2 A few reflections
199
5.3 Bibliography
200
6. Nanoparticles in the Environment and Working Places 203
6.1 Introduction
203
6.2 Chimneysweeps: a historical case
205
6.3 Welding metals
207
6.4 Toner
210
6.5 The particulate active filter or HAP
212
6.6 The environment around a foundry
215
6.7 The environment around a power plant
220
6.8 The case of a ship
227
6.9 Incinerators
228
6.10 Tobacco smoke
231
6.11 Bibliography
237
7. Nanoparticles in Food, Cosmetics and Other Products 239
7.1 Bibliography
249
8. New York 9/11 251
8.1 Bibliography
263
9. The Future and Prevention Criteria 265
9.1 The state of the art
265
9.2 What is next?
267
9.3 The future
280
9.4 A few reflections
281
9.5 Bibliography
284
Appendix 287
Index 291


Antonietta Morena Gatti is a physicist and bioengineer and the founder and director of the Laboratory of Biomaterials of the University of Modena and Reggio Emilia (Italy). She is the discoverer of the presence of micro- and nanoparticles in biological tissues and of their pathological effects. The European Community appointed her coordinator of the international group in charge of the nanopathology project. She was a keynote speaker on "Depleted Uranium Related Diseases" at the 2005 Audition at the House of Lords in London on the invitation of its president, Lord Morris of Manchester.