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El. knyga: Nervous System, E-Book: The Nervous System, E-Book

(Lecturer in Anatomy, Neuroscience Section, Queen Mary and Westfield College, London, UK), Series edited by , (Senior Lecturer in Neuroscience and Pharmacology, St Bartholomew's and the Royal London School of Medicine and Dentistry, London, UK)
  • Formatas: EPUB+DRM
  • Serija: Systems of the Body
  • Išleidimo metai: 11-Jun-2022
  • Leidėjas: Elsevier Health Sciences
  • Kalba: eng
  • ISBN-13: 9780702083419
  • Formatas: EPUB+DRM
  • Serija: Systems of the Body
  • Išleidimo metai: 11-Jun-2022
  • Leidėjas: Elsevier Health Sciences
  • Kalba: eng
  • ISBN-13: 9780702083419

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The Systems of the Body series has established itself as a highly valuable resource for medical and other health science students following today's systems-based courses. Now thoroughly revised and updated in this third edition, each volume presents the core knowledge of basic science and clinical conditions that medical students need, providing a concise, fully integrated view of each major body system that can be hard to find in more traditionally arranged textbooks or other resources. Multiple case studies help relate key principles to current practice, with links to clinical skills, clinical investigation and therapeutics made clear throughout.

Each (print) volume also now comes with access to the complete, enhanced eBook version, offering easy anytime, anywhere access - as well as self-assessment material to check your understanding and aid exam preparation.

The Nervous System

provides highly accessible coverage of the core basic science principles in the context of clinical case histories, giving the reader a fully integrated understanding of the system and its major diseases.

  • Organization of the Nervous System
  • Elements of Cellular and Molecular Neuroscience
  • Clinical Assessment
  • The Spinal Cord
  • Pain and Analgesia
  • Cranial Nerves and the Brainstem
  • The Visual System
  • Hearing and Balance: The Auditory and Vestibular Systems
  • Motor Systems I: Descending Pathways and Cerebellum
  • Motor Systems II: The Basal Ganglia
  • Stroke and Head Injury
  • Infection in the Central Nervous System
  • Epilepsy
  • Dementia
  • Schizophrenia and Neurodevelopmental Disorders
  • Depression and Anxiety
  • Addiction

Systems of the Body

Series:

  • The Renal System
  • The Musculoskeletal System
  • The Nervous System
  • The Digestive System
  • The Endocrine System
  • The Respiratory System
  • The Cardiovascular System
1 Organization Of The Nervous System
1(32)
Introduction
2(1)
Overview of brain anatomy
3(4)
Internal anatomy of the brain
7(5)
Forebrain
12(2)
Hemisphere specialization
14(2)
Limbic system
16(2)
Orbitofrontal cortex
18(1)
Basal ganglia
18(1)
Diencephalon
18(1)
Thalamus
18(1)
Hypothalamus
19(3)
Peripheral nervous system
22(8)
Putting it all together: from anatomy to behaviour
30(3)
2 Elements Of Cellular And Molecular Neuroscience
33(20)
Introduction
34(1)
Neurons
34(2)
Glial cells
36(3)
Neuron excitability
39(7)
Postsynaptic events and postsynaptic receptors
46(5)
Neurotransmitter synthesis
51(1)
Neurotransmitter inactivation
51(1)
Summation and neuronal integration
51(2)
3 Clinical Assessment
53(14)
Introduction
54(1)
Component parts of the clinical examination
55(7)
Other investigations
62(3)
General comments
65(2)
4 The Spinal Cord
67(22)
Introduction
68(1)
Gross anatomy of the spinal cord and vertebral column
68(1)
Functional organization of the spinal cord
69(3)
Spinal cord cell types
72(1)
Receptive fields
73(1)
Somatosensory pathways
73(7)
Blood supply to the spinal cord
80(1)
Damage to the spinal cord
80(6)
Comments on the case history
86(1)
Self-assessment case study
86(3)
5 Pain And Analgesia
89(30)
Introduction
90(2)
Nociceptors
92(1)
Pain pathways
93(1)
Visceral and muscular pain pathways
94(1)
How does the central nervous system interpret a stimulus as painful?
95(1)
Physiology of pain modulation
96(1)
Counter-stimulation analgesia
97(1)
Supraspinal (descending) analgesia
97(2)
Acupuncture analgesia
99(1)
Arousal analgesia
99(1)
Psychology of pain
100(1)
Measuring pain
100(1)
Pain mechanisms after tissue damage: peripheral and central sensitization
101(1)
Neuropathic pain mechanisms
102(2)
Glial cells and neuropathic pain
104(1)
Pharmacology of pain
104(3)
Opioid receptors and ligands
107(1)
Opioid analgesic drugs
108(1)
Opioid antagonists
108(2)
Pain sensitivity to opioids
110(1)
Non-opioid analgesics
110(1)
Other approaches to pain management
111(1)
Neuropathic pain
111(1)
Migraine
111(2)
Treatment of migraine attacks
113(2)
Preventive treatment of migraine
115(1)
Trigeminal neuralgia
116(1)
Pain in children and in the elderly
116(1)
General comments on pain management
117(1)
Self-assessment case study
118(1)
6 Cranial Nerves And The Brainstem
119(16)
Introduction
120(1)
Anatomical organization of cranial nerves and their nuclei
120(1)
Internal organization of the brainstem
121(2)
Reticular formation
123(3)
Blood supply to the brainstem
126(1)
Brainstem reflexes
126(4)
Brainstem lesions
130(2)
Comments on the case history
132(1)
Self-assessment case study
133(2)
7 The Visual System
135(22)
Introduction
136(1)
Structure of the eye
136(3)
Visual pathways
139(2)
Visual field defects
141(1)
Pupillary light reflexes
141(1)
Focusing of light on the retina
142(2)
Control of eye movements
144(2)
Structure and function of the retina
146(5)
Processing of visual information
151(4)
Summary
155(1)
Self-assessment case study
155(2)
8 Hearing And Balance: The Auditory And Vestibular Systems
157(20)
Introduction
158(1)
Auditory system
158(11)
Vestibular system
169(6)
Comments on the case history
175(1)
Self-assessment case study
176(1)
9 Motor Systems I: Descending Pathways And Cerebellum
177(24)
Introduction
178(1)
Skeletal muscle contraction
179(3)
Reflexes
182(4)
Descending pathways
186(5)
Clinical importance of reflexes
191(3)
The cerebellum
194(6)
Self-assessment case study
200(1)
10 Motor Systems II: The Basal Ganglia
201(22)
Introduction
202(1)
Basal ganglia: structure and organization
202(2)
Parkinson's disease
204(14)
Huntington's disease
218(3)
Self-assessment case study
221(2)
11 Stroke And Head Injury
223(32)
Introduction
224(1)
Physiological control of cerebral blood flow
225(1)
Blood supply to the brain
226(3)
Stroke
229(14)
Head injury
243(2)
Focal pathology in relation to vascular injury
245(6)
Treatment of head injury
251(2)
Comments on the case history
253(1)
Self-assessment case study
254(1)
12 Infection In The Central Nervous System
255(18)
Introduction
256(1)
Types of infection of the central nervous system
256(1)
The meninges
257(2)
Cerebrospinal fluid production and circulation
259(4)
Meningitis
263(5)
Encephalitis
268(1)
Cerebral abscesses
269(1)
Brain infections in the immunocompromised patient
270(1)
Self-assessment case study
271(2)
13 Epilepsy
273(22)
Introduction
274(1)
General description of epilepsy
274(1)
Epidemiology and causes of epilepsy
275(1)
Diagnostic investigations of epilepsy
276(6)
Examples of types of seizure
282(5)
Pharmacological treatment of epilepsy
287(4)
Other treatments for epilepsy
291(1)
Treatment of status epilepticus
292(1)
Social consequences of epilepsy
292(1)
Self-assessment case study
293(2)
14 Dementia
295(22)
Introduction
296(1)
Causes and diagnosis of dementia
296(3)
Neurobiology of learning and memory
299(3)
Alzheimer's disease
302(6)
Treatment of Alzheimer's disease
308(4)
Other types of dementia
312(2)
General considerations in the management of Alzheimer's disease and other types of dementia
314(1)
Self-assessment case study
315(2)
15 Schizophrenia And Neurodevelopmental Disorders
317(16)
Introduction
318(1)
Schizophrenia: the clinical diagnosis
318(3)
Aetiology of schizophrenia
321(1)
Neurobiology of schizophrenia
322(5)
Treatment of schizophrenia
327(3)
Comments on the management of schizophrenia and the long-term prognosis
330(1)
Other psychoses and neurodevelopmental disorders
331(1)
Self-assessment case study
332(1)
16 Depression And Anxiety
333(22)
Introduction
334(1)
Classification of mood disorders
334(1)
Clinical features of mood disorders
334(1)
Epidemiology of depressive and bipolar disorders and their natural evolution
335(4)
Genetics of mood disorders
339(1)
Neurobiology of depression
339(2)
Treatment of depression
341(4)
Bipolar disorder and its treatment
345(1)
General comments on mood disorders
346(1)
Need for new therapeutic targets
347(1)
Comments on case history
348(1)
Anxiety disorders
348(1)
Treatment of anxiety disorders
349(2)
Insomnia
351(3)
Self-assessment case study
354(1)
17 Addiction
355(18)
Introduction
356(1)
Addiction and drug misuse: general comments
356(1)
Neurobiology of addiction
357(14)
Addiction and rehabilitation: general comments
371(1)
Self-assessment case study
372(1)
Index 373