"Down syndrome is one of the most commonly occurring developmental disorders and it is now possible to conceptualize and define opportunities for neurocognitive rehabilitation for those with the condition. This book describes how early cognitive intervention in children with Down syndrome can be carried out, and can reduce, or compensate for, the major deficits characteristic of the condition. This comprehensive account relates the neurocognitive approach to the major therapeutic endeavors in the neighboring fields of neurogenetics, experimental environmental enrichment, molecular genetics, pharmacology, pediatrics and cardiology for infants with Down syndrome. Neurocognitive Rehabilitation of Down Syndrome provides the guidance required to establish effective rehabilitation programs, and is essential reading for developmental clinicians, pediatricians, neuropsychologists and other health professionals"--Provided by publisher.
Daugiau informacijos
Describes how early cognitive intervention in children with Down syndrome can reduce, or compensate for, the major characteristic deficits.
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ix | |
Preface |
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xi | |
Acknowledgements |
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xiii | |
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Section 1 Definition, history, methodology, and assessment |
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1 Early rehabilitative intervention: definition, objectives, models, and challenges |
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1 | (14) |
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2 The history of early intervention for infants and young children with Down syndrome and their families: where have we been and where are we going? |
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15 | (21) |
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3 Advances in clinical endpoints for neurocognitive rehabilitation in Down syndrome |
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36 | (16) |
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Section 2 Genetics, brain, and animal models |
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4 New perspectives on molecular and genie therapies in Down syndrome |
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52 | (19) |
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5 Brain plasticity and environmental enrichment in Ts65Dn mice, an animal model for Down syndrome |
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71 | (14) |
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6 Development of the brain and metabolism |
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85 | (11) |
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Section 3 Pharmacological and medical management and treatment |
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7 Pharmacotherapy for children with Down syndrome |
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96 | (21) |
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8 Early medical caretaking and follow-up |
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117 | (11) |
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9 Evaluation and management of cardiovascular diseases in Down syndrome |
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128 | (14) |
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Section 4 Early development and intervention |
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10 Developmental models as frameworks for early intervention with children with Down syndrome |
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142 | (11) |
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11 Aspects of motor development in Down syndrome |
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153 | (11) |
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12 Memory development and learning |
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164 | (11) |
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13 Prelinguistic and early development, stimulation, and training in children with Down syndrome |
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175 | (7) |
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14 Speech perception, stimulation, and phonological development |
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182 | (9) |
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15 Goal-directedness as a target for early intervention in Down syndrome |
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191 | (14) |
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16 The role of parents of children with Down syndrome and other disabilities in early intervention |
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205 | (19) |
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Section 5 Therapeutic perspectives |
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17 Perspectives of hybrid therapeutic strategies in intellectual disabilities and Down syndrome |
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224 | (6) |
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Conclusions |
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230 | (1) |
Index |
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231 | |
Jean-Adolphe Rondal PhD is Emeritus Professor of Psycholinguistics and Neuropsychology of Language at the University of Ličge, Belgium and Professor at the International School of the Pontifical Salesian University, Venice, Italy. Juan Perera PhD is Director of the Centro Prķncipe de Asturias, University of the Balearic Islands, Mallorca, Spain. Donna Spiker PhD is General Manager of the Early Childhood Program, Center for Education and Human Services, SRI International, Menlo Park, CA, USA.