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El. knyga: Neuromodulation: Comprehensive Textbook of Principles, Technologies, and Therapies

Edited by (Pacific Pain Treatment Center, San Francisco, CA, USA), Edited by (Donnell Institute Professor of Biomedical Engineering and Orthopaedics at Case Western Reserve University and Director, Cleveland Functional Electrical Stimulation Center.), Edited by (exe)
  • Formatas: EPUB+DRM
  • Išleidimo metai: 05-Jan-2018
  • Leidėjas: Academic Press Inc
  • Kalba: eng
  • ISBN-13: 9780128093023
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  • Formatas: EPUB+DRM
  • Išleidimo metai: 05-Jan-2018
  • Leidėjas: Academic Press Inc
  • Kalba: eng
  • ISBN-13: 9780128093023
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Neuromodulation: Comprehensive Textbook of Principles, Technologies, and Therapies, Second Edition, serves as a comprehensive and in-depth reference textbook covering all aspects of the rapidly growing field of neuromodulation. Since the publication of the first edition seven years ago, there has been an explosion of knowledge in neuromodulation, optogenetics, bioelectronics medicine and brain computer interfacing. Users will find unique discussions of the fundamental principles of neuromodulation and therapies, and how they are applied to the brain, spinal cord, peripheral nerves, autonomic nerves and various organs.

The book focuses on comprehensive coverage of spinal cord stimulation, non-interventional and interventional brain stimulation, peripheral nerve stimulation, and the emerging fields of neuromodulation, including optogenetics and bioelectronics medicine.

  • Provides a comprehensive reference that covers all aspects of the growing field of neuromodulation
  • Written by international, leading authorities in their respective fields of neuromodulation, pain management, functional neurosurgery and biomedical engineering
  • Includes new chapters on optogenetics, bioelectronics medicine and brain computer interfacing

Daugiau informacijos

Comprehensive overview of the growing field of neuromodulation, with chapters covering the fundamental principles of neuromodulation and therapies
Volume 1
List of Contributors
ix
Foreword
xi
I Defining Neuromodulation
Elliot S. Krames
Ali R. Rezai
P. Hunter Peckham
1 Perspectives on the History of Neuromodulation-Relevant Societies
3(12)
Elliot S. Krames
Konstantin V. Slavin
Giancarlo Barolat
Brian Simpson
Michael Stanton-Hicks
2 Psychological Issues and Evaluation for Patients Undergoing Implantable Technology
15(10)
Daniel M. Doleys
Jeffery J. Dolce
3 Anatomy of the Nervous System
25(16)
Joshua M. Rosenow
4 Clinical Study Designs for Neuromodulation
41(14)
Richard B. North
Jane Shipley
II Introduction To The Brain Initiative
P. Hunter Peckham
5 The Brain Initiative-Implications for a Revolutionary Change in Clinical Medicine via Neuromodulation Technology
55(16)
Elizabeth M. Mosier
Michael Wolfson
Erika Ross
James Harris
Doug Weber
Kip A. Ludwig
III Fundamentals And Mechanisms Of Neuromodulation
Joseph J. Pancrazio
6 Fundamentals of Electrical Stimulation
71(12)
John T. Mortimer
Narendra Bhadra
7 The Safe Delivery of Electrical Currents and Neuromodulation
83(12)
Stuart F. Cogan
Seth Hara
Kip A. Ludwig
8 Waveforms for Neural Stimulation
95(8)
Warren M. Grill
9 Neuromodulation and Neuronal Plasticity
103(8)
Alon Y. Mogilner
10 Fundamentals of Kilohertz Frequency Alternating Current Nerve Conduction Block of the Peripheral Nervous System
111(10)
Niloy Bhadra
Kevin L. Kilgore
11 MRI and fMRI for Neuromodulation
121(8)
Francesco Sammartino
Vibhor Krishna
Ali R. Rezai
12 Patient-Specific Modeling of Deep Brain Stimulation
129(8)
Cameron C. McIntyre
13 Big Data and Deep Brain Stimulation
137(10)
Pierre-Francois D'Haese
Peter E. Konrad
Benoit M. Dawant
14 Fundamentals of Burst Stimulation of the Spinal Cord and Brain
147(14)
Dirk De Ridder
Tim Vancamp
Sven Vanneste
15 Spinal Cord Stimulation: Mechanisms of Action
161(18)
Yun Guan
Kerry Bradley
John L. Parker
Elliot S. Krames
Bengt Linderoth
16 Fundamentals and Mechanisms of Dorsal Root Ganglion Stimulation
179(14)
Jeffery Kramer
Allison Foster
Alexander R. Kent
William Cusack
17 Mechanisms of Action of Deep Brain Stimulation: A Review
193(18)
Kendall H. Lee
Elizabeth M. Mosier
Charles D. Blaha
18 Vagus Nerve Stimulation: Mechanism of Action
211(10)
Kristl E.J. Vonck
Lars E. Larsen
19 Mechanisms of Action of Sacral Nerve and Peripheral Nerve Stimulation for Disorders of the Bladder and Bowel
221(18)
William C. de Groat
Changfeng Tai
IV Technology And Devices
Kip A. Ludwig
20 Electrodes for the Neural Interface
239(36)
Dustin J. Tyler
21 Implantable Neural Stimulators
275(14)
P. Hunter Peckham
D. Michael Ackermann
22 Microstimulators: Minimally Invasive Implantable Neuromodulatory Devices
289(16)
Benjamin Pless
Amy M. Goodman
23 Designing Neuromodulation Devices for Feedback Control
305(10)
Christopher L. Pulliam
Erik J. Peterson
Jeffrey A. Herron
Timothy Denison
24 MRI Safety and Neuromodulation Systems
315(26)
Steve G. Manker
Frank G. Shellock
V Brain, Computer And Machine Interfacing
Bin He
25 Brain-Computer Interfaces: Why Not Better?
341(16)
John P. Donoghue
26 Noninvasive Brain-Computer Interfaces
357(22)
Gerwin Schalk
Brendan Z. Allison
27 Invasive Brain-Computer Interfaces for Functional Restoration
379(14)
Abidemi B. Ajiboye
Robert F. Kirsch
28 Prospects for a Robust Cortical Recording Interface
393(22)
Andrew Shoffstall
Jeffrey R. Capadona
29 Advances in Invasive Brain-Computer Interface Technology and Decoding Methods for Restoring Movement and Future Applications
415(14)
Chad E. Bouton
VI Emerging Technologies And Techniques
Ali R. Rezai
30 Gene-Based Neuromodulation
429(14)
Hilarie C. Tomasiewicz
Gary Kocharian
Michael G. Kaplitt
31 Focused Ultrasound Ablation for Neurological Disorders
443(8)
Francesco Sammartino
Toacca Taylor
Ali R. Rezai
Vibhor Krishna
32 Implanted Sensors in Neuromodulation via Electrical Stimulation
451(14)
John L. Parker
33 Gaming for the Brain: Video Gaming to Rehabilitate the Upper Extremity After Stroke
465(12)
Lynne V. Gauthier
Troy A. Richter
Lydia C. George
Kathryn M. Schubauer
34 The Use of New Surgical Technologies for Deep Brain Stimulation
477(10)
Vibhor Krishna
Francesco Sammartino
Ali R. Rezai
35 Neuromodulation Using Optogenetics and Related Technologies
487(16)
Nigel P. Pedersen
Robert E. Gross
VII Surgical Procedures And Techniques
Elliot S. Krames
Ali R. Rezai
36 Deep Brain Stimulation: Surgical Technique
503(10)
Alon Y. Mogilner
Andre G. Machado
Ali R. Rezai
37 Spinal Cord Stimulation: Placement of Surgical Leads via Laminotomy: Techniques and Benefits
513(10)
Donald Y. Ye
Jonathan Riley
Ravichandra Madineni
Shannon W. Clark
Chengyuan Wu
Steven M. Falowski
Ashwini D. Sharan
38 Subcutaneous Peripheral Nerve Field Stimulation for Intractable Pain
523(6)
Konstantin V. Slavin
Dali Yin
Hang Yin
Christy Gomez
39 Surgical Placement of Leads for Occipital Nerve Stimulation
529(8)
Richard L. Weiner
40 Surgical Technique: Intrathecal Medication Delivery System Implantation
537(6)
Joshua M. Rosenow
41 Neuroprosthetic Surgical Strategies for Neuromuscular Stimulation
543(8)
Michael W. Keith
Harry A. Hoyen
42 The Surgical Technique of Vagus Nerve Stimulator Implantation
551(14)
Jeffrey W. Cozzens
Volume 2
List of Contributors
xi
Foreword
xv
VIII Neuromodulation For Pain Control
VIIIA Spinal Cord Stimulation for Pain Control
Salim M. Hayek
43 Physiology and Pathophysiology of Chronic Pain
565(1)
Nicole Bentley
Ahmed J. Awad
Parag G. Patil
44 Management Strategies for Chronic Pain
575(1)
Keeley Dohmeier
Sailesh Arulkumar
Salim M. Hayek
Lawrence R. Poree
45 History of Spinal Cord Stimulation
587(1)
Richard B. North
Joshua P. Prager
46 Functional Magnetic Resonance Imaging in the Neuromodulation of Pain
597(1)
Ernest J. Barthelemy
Jonathan J. Rasouli
Kurt A. Yaeger
Brian H. Kopell
47 The Development of Algorithms for Pain Care Including Neuromodulation Therapies: Introducing the SAFE Principles
609(1)
Prasad Shirvalkar
Lawrence R. Poree
Elliot S. Krames
48 Neurostimulation for the Treatment of Complex Regional Pain Syndrome
617(1)
Michael Stanton-Hicks
Joshua P. Prager
49 Spinal Cord Stimulation for Peripheral Neuropathic Pain
633(1)
Brigitte A. Brouwer
Bert Joosten
Maarten van Kleef
50 Spinal Cord Stimulation for the Treatment of Low Back Pain
647(1)
Richard B. North
51 Complications of Spinal Cord Stimulation
657(1)
Mark N. Malinowski
Chong H. Kim
Timothy R. Deer
52 Clinical Aspects of Burst Stimulation for Pain Control
669(1)
Stefan Schu
Tim Vancamp
53 Dorsal Root Ganglion Stimulation for Pain Control
683(1)
Paul Verrills
54 Ten Kilohertz (10kHz) High-Frequency Spinal Cord Stimulation
693(1)
Kapural Leonardo
Al-Kaisy Adnan
55 A Review of Spinal Cord Stimulation Cost Studies
701(1)
Jane Shipley
Richard B. North
VIIIB Peripheral Nerve Stimulation for Pain Control
Konstantin V. Slavin
56 Anatomy and Physiology Related to Peripheral Nerve Stimulation
723(1)
Michael Stanton-Hicks
57 Peripheral Nerve Stimulation for Pain Suppression
729(1)
Joseph W. Boggs
John Chae
Maria E. Bennett
58 Peripheral Nerve Stimulation for Facial Pain
741(1)
Konstantin V. Slavin
Dali Yin
Serge Rasskazoff
59 Combined Spinal Cord Stimulation and Peripheral Nerve Field Stimulation for the Treatment of Chronic Back and Neck Pain
747(1)
Dali Yin
Konstantin V. Slavin
60 Percutaneous Peripheral Nerve Stimulation for the Management of Postoperative Pain
753(1)
Amorn Wongsarnpigoon
Brian M. Ilfeld
61 Peripheral Nerve Field Stimulation for Intractable Pain
763(1)
Giancarlo Barolat
62 Occipital Nerve Stimulation for Treatment of Intractable Headache Syndromes
773(1)
Richard L. Weiner
Kenneth M. Alo
63 Neuromodulation for Headaches-Sphenopalatine Ganglion Stimulation
783(1)
Stewart J. Tepper
Anthony Caparso
VIIIC Intrathecal Therapies for Pain Control and the Control of Spasticity
Lawrence R. Poree
64 Relevant Anatomy for Spinal Drug Delivery
793(1)
Mark N. Malinowski
Chong H. Kim
Timothy R. Deer
65 Evolution of the Spinal Delivery of Opiate Analgesics
803(1)
Deepali Dhar
Lawrence R. Poree
Tony L. Yaksh
66 Pharmacology of Intrathecal Therapy
819(1)
Lucas W. Campos
Jason E. Pope
67 Cerebrospinal Fluid Dynamics and Intrathecal Delivery
829(1)
Kevin Tangen
Ankit I. Mehta
Andreas A. Linninger
68 Exploring Nonopioid Analgesic Agents for Intrathecal Use
847(1)
Jason Kyung-soo Hong
Richard Rauck
69 Potent Neurotoxins for Cancer Pain Treatment: Resiniferatoxin and Saporin
861(1)
Michael S. Leong
David Copenhaver
70 The Development of Guidelines for Intrathecal Therapies for Pain Control. History and Present Guidelines
869(1)
Mark N. Malinowski
Chong H. Kim
Timothy R. Deer
71 Compounding for Intrathecal Analgesic Agents
879(1)
William A. Stuart
72 Intrathecal Baclofen Therapy for the Control of Spasticity
889(1)
Michael Saulino
VIIID Intracranial Procedures for Chronic Pain
Alon Y. Mogilner
73 Deep Brain Stimulation for Pain
903(1)
Neil U. Barua
Nikunj K. Patel
IX Neuromodulation For Movement Disorders
Brian Harris Kopell
74 Deep Brain Stimulation in Parkinson's Disease
911(8)
Reversa Mills-Joseph
Vibhor Krishna
Milind Deogaonkar
Ali R. Rezai
75 Deep Brain Stimulation for Tremor
919(12)
Michael H. Pourfar
Michael Okun
Kelly Foote
Alon Y. Mogilner
76 Deep Brain Stimulation for Dystonia
931(14)
Ron L. Alterman
Scellig Stone
77 Deep Brain Stimulation in Tourette Syndrome
945(8)
Pablo Andrade
Martin Klehr
Veerle Visser-Vandewalle
78 Surgical Management of Hemifacial Spasm and Meige Syndrome
953(14)
Na Young Jung
Jin Woo Chang
79 Deep Brain Stimulation of the Pedunculopontine Tegmental Nucleus Improves Static Balance in Parkinson's Disease
967(10)
Paolo Mazzone
Flora Vitale
Annamaria Capozzo
Fabio Viselli
Eugenio Scarnati
80 Infusion Therapy for Movement Disorders
977(10)
Neil U. Barua
Steven S. Gill
X Neurostimulation For Epilepsy
Jonathan Riley
Ashwini D. Sharan
81 Epilepsy: Anatomy, Physiology, Pathophysiology, and Disorders
987(12)
Robrecht Raedt
Dominique M. Durand
Paul Boon
Kristl Vonck
Elliot S. Krames
82 Vagal Nerve Simulation
999(12)
Vivek Mehta
Daniel Kramer
Jonathan Russin
Charles Liu
Arun Amar
83 Deep Brain Stimulation for Epilepsy
1011(12)
Paul Koch
Gordon Baltuch
84 Closed-Loop Responsive Stimulation for Epilepsy
1023(10)
Abraham Sabersky
Michael Mackow
Balu Krishnan
Dileep Nair
Andreas Alexopoulos
William Bingaman
Jorge Gonzalez-Martinez
XI Neuromodulation For Behavioral And Cognitive Disorders
Paul E. Holtzheimer
85 Deep Brain Stimulation for Obsessive-Compulsive Disorder
1033(12)
Mayur Sharma
Kevin Reeves
Milind Deogaonkar
Ali R. Rezai
86 High-Intensity Focused Ultrasound Surgery for the Treatment of Obsessive-Compulsive Disorder
1045(12)
Young Goo Kim
Jin Woo Chang
87 Deep Brain Stimulation for Highly Refractory Depression
1057(16)
Darin D. Dougherty
Alik S. Widge
Benjamin D. Greenberg
88 Neuromodulation in Anorexia Nervosa
1073(8)
Nir Lipsman
Andres M. Lozano
Clement Hamani
89 Deep Brain Stimulation for Alcoholism
1081(8)
Sina Kohl
Jens Kuhn
90 Surgical Treatment for Refractory Drug Addiction
1089(10)
Chencheng Zhang
Tao Wang
Kristina Zeljic
Haiyan Jin
Shikun Zhan
Dianyou Li
Xuelian Wang
Bomin Sun
91 Subgenual Cingulate Deep Brain Stimulation for Treatment-Resistant Depression
1099(20)
Yarerna B. Bezchlibnyk
Jennifer Cheng
Kelly R. Bijanki
Helen S. Mayberg
Robert E. Gross
92 Cortical Stimulation for Depression
1119(12)
Jeffrey Gilligan
Jonathan J. Rasouli
Brian H. Kopell
List of Contributors
xi
Foreword
xv
Volume 3
XII Neuromodulation For Functional Restoration
P. Hunter Peckham
Kevin L. Kilgore
93 The History of Neuromuscular Electrical Stimulation-The Evolution of Functional Neuromuscular Stimulation and Future Directions
1131(6)
P. Hunter Peckham
94 Functional Electrical Stimulation for Return of Function After Stroke
1137(10)
Jayme S. Knutson
Richard D. Wilson
Nathaniel S. Makowski
John Chae
95 Invasive Neurostimulation for Poststroke Motor Recovery
1147(12)
Connor A. Wathen
Kenneth B. Baker
Andre G. Machado
96 Stimulation for Return of Upper-Extremity Function
1159(12)
Kevin L. Kilgore
P. Hunter Peckham
97 Lower Extremity Motor System Neuroprostheses
1171(12)
Musa Audu
Rudi Kobetic
Stephen Selkirk
Ronald J. Triolo
98 Neuromodulation of the Spinal Cord for Movement Restoration
1183(14)
Susan J. Harkema
Enrico Rejc
Claudia A. Angeli
99 A Brief History of the Cochlear Implant and Related Treatments
1197(12)
Blake S. Wilson
Michael F. Dorman
100 Stimulation for the Return of Hearing
1209(14)
Blake S. Wilson
Michael F. Dorman
101 The Development of Visual Prosthetic Devices to Restore Vision to the Blind
1223(12)
James D. Weiland
Mark S. Humayun
Alejandra Gonzalez Calle
102 Neuromodulation for Treatment of Dry Eye
1235(14)
Manfred Franke
James Loudin
D. Michael Ackermann Jr
103 Neuroprostheses for Restoring Sensation
1249(16)
Dustin J. Tyler
XIII Neuromodulation For Organ Systems
XIIIA Neuromodulation for Cardiovascular Disorders
William T. Abraham
104 Autonomic Control of the Heart
1265(1)
Una Buckley
Jeffrey L. Ardell
105 Spinal Cord Stimulation for Peripheral Vascular Disorders
1273(1)
Stefan Schulte
Svante Horsch
106 Neuromodulation for Refractory Angina and Heart Failure
1279(1)
Paulin Andrell
107 Baroreceptor Activation for Hypertension and Heart Failure
1293(1)
Marabel Schneider
Ayhan Yoruk
John P. Gassier
XIIIB Neuromodulation for Pulmonary Disorders
Peter Staats
108 Upper Airway Neurostimulation to Treat Obstructive Sleep Apnea
1307(1)
Elizabeth G. Damato
Michael J. Decker
Matthew A. Schiefer
Jonathan Z. Baskin
Girriso F. Benderro
Kingman P. Strohl
109 A Neural Prosthesis for Obstructive Sleep Apnea
1321(1)
Dominique M. Durand
110 Transvenous Phrenic Nerve Stimulation for Central Sleep Apnea
1331(1)
William T. Abraham
Robin Elizabeth Germany
111 Neurostimulation for Asthma
1339(1)
Peter Staats
Charles Emala
Bruce Simon
J.P. Errico
112 Stimulation for Inspiration
1347(1)
Raymond P. Onders
113 Restoration of Cough via Functional Electrical Stimulation
1355(1)
Anthony F. DiMarco
Krzysztof E. Kowalski
XIIIC Neuromodulation for Gastrointestinal Disorders
Elliot S. Krames
Jiande D.Z. Chen
Thomas Abell
114 Neural Control of the Gastrointestinal System
1373(1)
Drew Murray
Thomas Abell
115 Spinal Cord Stimulation for Chronic Abdominal Pain
1379(1)
Leonardo Kapural
116 Emerging Gastric Stimulation for Dysmotility Disorder and Obesity
1387(1)
Jiande D.Z. Chen
Jieyun Yin
117 Intestinal Electrical Stimulation: Methodologies, Effects, Mechanisms, and Applications
1397(1)
Jieyun Yin
Jiande D.Z. Chen
118 Neuromodulation for Nausea and Vomiting in Adult Patients
1407(1)
Drew Murray
Thomas Abell
119 Neuromodulation for Gastrointestinal Dysmotility in Pediatric Patients
1419(1)
Peter L. Lu
Hayat M. Mousa
120 Colonic Electrical Stimulation for Constipation
1427(1)
Shukun Yao
Yanmei Li
Shuo Chen
XIIID Neuromodulation for Urogenital Disorders
Joshua A. Cohn
Casey G. Kowalik
William S. Reynolds
Melissa R. Kaufman
Douglas F. Milam
Roger R. Dmochowski
121 Neurophysiology and Neuroanatomy of the Genitourinary Organs
1437(1)
William C. de Groat
122 Sacral Nerve Neuromodulation
1451(1)
Magdy Hassouna
Ali Alabbad
123 Sacral Nerve Root Stimulation for Bladder Pain Syndrome/Interstitial Cystitis
1455(1)
Sachin Mall
Arun Sahai
Adnan Al-Kaisy
124 Restoration of Bladder and Bowel Control After Spinal Cord Injury
1471(1)
Graham H. Creasey
XIV Neuromodulation For Endocrine, Immune, And Inflammatory Disorders
Christopher J. Czura
Chad E. Bouton
125 Vagus Nerve Stimulation and Regulation of Inflammation
1483(10)
Peder S. Olofsson
126 Activation of the Inflammatory Reflex in Rheumatoid Arthritis and Inflammatory Bowel Disease; Preclinical Evidence
1493(10)
Yaakov A. Levine
Michael Faltys
Ralph Zitnik
127 Bioelectronic Therapy for the Treatment of Rheumatoid Arthritis and Inflammatory Bowel Disease
1503(10)
Yaakov A. Levine
Jesse Simon
Michael Faltys
Ralph Zitnik
128 Vagal Nerve Stimulation Versus Sacral Nerve Stimulation for Control of Inflammation
1513(6)
Jiande D.Z. Chen
Haifeng fin
Jieyun Yin
129 Neuromodulation Therapies for Cardiac Disease
1519(12)
Siamak Salavatian
Jeffrey L. Ardell
130 The Neural Tourniquet
1531(10)
Jared M. Huston
Jason R. Fritz
Christopher J. Czura
131 Sensing and Decoding Neural Signals for Closed-Loop Neuromodulation and Advanced Diagnostics in Chronic Disease and Injury
1541(10)
Chad E. Bouton
Christopher J. Czura
132 The Role of Vagus Nerve Stimulation in the Treatment of Central and Peripheral Pain Disorders and Related Comorbid Somatoform Conditions
1551(14)
J.P. Errico
133 Insulin Resistance, Glucose Metabolism, Inflammation, and the Role of Neuromodulation as a Therapy for Type-2 Diabetes
1565(12)
J.P. Errico
XV Noninvasive Neuromodulation
Felipe Fregni
134 Transcranial Magnetic Stimulation
1577(12)
Jorge Leite
Marcel Simis
Sandra Carvalho
Felipe Fregni
135 Transcranial Direct Current Stimulation (tDCS)
1589(22)
Gozde Unal
Marom Bikson
136 Transcranial Alternating Current Stimulation and Transcranial Random Noise Stimulation
1611(8)
Sandra Carvalho
Jorge Leite
Felipe Fregni
137 Novel Methods of Transcranial Stimulation: Electrosonic Stimulation
1619(8)
Timothy Wagner
Laura Dipietro
138 Optimization of Noninvasive Brain Stimulation Clinical Trials
1627(10)
Aurore Thibaut
Melanie French
Alejandra Vasquez
Felipe Fregni
139 Transcranial Direct Current Stimulation for Fatigue and Attentional Disorders
1637(14)
Richard Andrew McKinley
XVI The Business End Of Neuromodulation
P. Hunter Peckham
140 Perspectives on the Issues and Barriers to Starting a New Neuromodulation Company From New Start-Ups in Neuromodulation
1651(14)
Elliot S. Krames
Jon Snyder
Anthony Arnold
Yaakov Levine
Maria E. Bennett
Laura Perryman
141 The Birth of an Industry
1665(10)
James Cavuoto
142 Neuromodulation: Regulatory Considerations
1675(12)
Megan Moynahan
143 Reimbursement for Neuromodulation Therapies and Technologies
1687(16)
Elliot S. Krames
Alon Y. Mogilner
Rui V. Duane
Simon J. Thomson
Fabian Piedemonte
144 Perspective on How to Build a Neuromodulation Practice
1703(8)
Giancarlo Barolat
Alon Y. Mogilner
Joshua P. Prager
Index
1711
Elliot S. Krames, MD, is a board-certified anesthesiologist who has been practicing pain medicine solely since 1987. He is a worldwide-recognized leader and educator in the field of neuromodulation for pain control. He has written extensively on implantable technologies for pain management and has conducted national and international symposia related to this topic. He is co-founder of the National Pain Foundation, a founding member of the North American Neuromodulation Society and has participated on the boards of the North American Neuromodulation Society, the International Neuromodulation Society, the World Institute of Pain, the American Academy of Pain Medicine, and the American Board of Pain Medicine. Dr. Krames has published more than 100 research papers, serves on several editorial boards, and co-edited a number of books. Dr. Krames was the founding editor of Neuromodulation: Technology at the Neural Interface, the journal of the International Neuromodulation Society, serving as Editor-in-Chief from 1998 until September 2009, when he became Emeritus Editor-in-Chief. Dr. Krames served as INS President from 2006 to 2009, as immediate Past President from 2009 to 2011, and since 2011 has been Emeritus Director-at-Large. Dr. Peckham is the Donnell Institute Professor of Biomedical Engineering and Orthopaedics at Case Western Reserve University and Director, Cleveland Functional Electrical Stimulation Center. The major area of Dr. Peckham's research is in rehabilitation engineering and neuroprostheses. Hes also the Founder for the Institute for Functional Restoration at the Case Western School of Medicine and the Co-Director of MetroHealth Rehabilitation Institute of Ohio. A holder of eight patents, he is a member of multiple councils, Dr. Peckham is also a fellow of the American Institute of Medical and Biological Engineering. Dr. Rezai is currently executive chair and vice president of neurosciences for WVU Medicine. He also serves as associate dean and the John D. Rockefeller IV tenured professor in neurosciences at the WVU School of Medicine. Dr. Rezai has published over 150 peer reviewed articles, more than 30 book chapters, and serves on the editorial board of five journals. Dr. Rezai is currently the Past President of the Congress of Neurological Surgeons (CNS), the largest neurosurgical societies in the world, as well as the Past President North American Neuromodulation Society (NANS), and the American Society of Stereotactic and Functional Neurosurgery (ASSFN).Dr. Rezais research focuses on mechanisms of neurostimulation, and developing neuromodulation devices and novel therapeutic strategies for treatment of neurological disorders.