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El. knyga: Neurotransmitter Receptors in Actions of Antipsychotic Medications

Contributions by (University of Maryland University of Maryland University of Maryland, Baltimore, MD, ), Contributions by , Contributions by , Contributions by (University of Toronto), Series edited by (University of California, Davis, USA), Contributions by , Edited by (University of Maryland, Baltimore, Maryland, USA), Contributions by , Contributions by , Contributions by (Washington State University)
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Years of extensive investigation into neurophysiology, neurochemistry, and behavioral pharmacology have produced an understanding of antipsychotic medication action that is much more refined than the original dopamine hypothesis. New perspectives offer an array of novel drugs - drugs that pose a lower risk of developing tardive dyskinesia, have fewer extrapyramidal side effects, are less sedating, and attempt to address the negative symptoms of schizophrenia. Neurotransmitter Receptors in Actions of Antipsychotic Medications presents a glimpse into the development of these breakthroughs and the field's current status in one definitive volume.

The exhaustive chapters cover the basic knowledge of schizophrenic syndromes and provide a general description of available antipsychotic drugs. Leading specialists recount the investigation into a variety of receptors in drug action and present unique topics like endogenous receptor occupation by antipsychotic drugs and regulation of brain receptors. The book also includes a survey of the future perspectives in drug design.

Each year, pharmaceutical companies invest billions of dollars in developing hundreds of medications to treat psychiatric disorders. Neurotransmitter Receptors in Actions of Antipsychotic Medications helps you study and appreciate the dynamics of these medications. You will understand the effects on receptors; predict the action, adverse side effects, and drug-drug interactions; and improve the modern antipsychotic medications that already enable people coping with schizophrenia to work, have meaningful social relationships, and live more productive lives.

Recenzijos

"This small but very thorough textbookan excellent contribution to the fields of psychiatry and neurosciencea rather complicated subject is presented in a well-organized and thorough mannera highly detailed review of antipsychotic drugs and neuroreceptors. There are many reviews of psychopharmacology, but this is one of the most specialized and exhaustive I have read. Any clinician or researcher interested in antipsychotic medications would find it a useful addition to their library." -William Miles, M.D., Rush-Presbyterian-St. Luke's Medical Center

Schizophrenic Syndromes 1(16) Peter F. Liddle General Overview of Contemporary Antipsychotic Medications 17(14) Michael S. Lidow Effects of Antipsychotic Drugs on Dopamine Release and Metabolism in the Central Nervous System 31(12) J. David Jentsch Robert H. Roth Antipsychotic Drugs, Dopamine D2 Receptors, and Schizophrenia 43(22) Philip Seeman D1 Dopamine Receptors, Schizophrenia, and Antipsycbhotic Medications 65(14) Akeo Kurumaji Yoshiro Okubo Serotonin Receptors as Targets of Antipsychotic Medications 79(30) Anissa Abi-Dargham John Krystal Role of Adrenergic Receptors in Effects of Antipsychotic Medications on Prefrontal Cortical Function 109(12) Amy F. T. Arnsten Glutamate Receptors in Schizophrenia and Antipsychotic Drugs 121(16) Donald C. Goff The Antipsychotic Effects of Sigma Drugs 137(16) Ralf-Michael Frieboes Axel Steiger GABAergic Drugs in Schizophrenia 153(10) Adel A. Wassef Receptor Occupancy by Antipsychotics --- Concepts and Findings 163(14) Shitij Kapur Regulation of Neurotransmitter Receptors by Antipsychotic Drugs 177(22) Lisa A. Taylor Ian Creese Modulation of Cellular Signaling Pathways by Antipsychotic Drugs 199(22) Ashiwel S. Undie The Role of Neurotransmitter Receptors in the Adversive Effects of Antipsychotic Drugs 221(22) Ronald E. See Future Perspectives in Antipsychotic Drug Development 243(4) W. Wolfgang Fleischhacker Josef Marksteiner Index 247
Michael S. Lidow
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