Research has clearly established a link between omega fatty acids and general health, particularly cardiovascular health. Omega Fatty Acids in Brain and Neurological Health, Second Edition, illustrates the importance of omega-3 fatty acids in longevity, cognitive impairment and structure and function of the brain's neurons and also the adverse effects of omega-6 fatty acids on neurological function. This book encompasses some of the most recent research on the links between omega fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis, including the role of omega-3 fatty acid supplements on hippocampal neurogenesis, substantia nigra modulation, migraine headaches, the developing brain in animals, sleep and neurodegenerative diseases. This completely updated second edition focuses on the counterbalancing dietary and tissue omega-6 fatty acids as well as it studies the effects in pregnancy and early infancy, animal model studies and autoimmune neurological diseases.
- Provides a comprehensive introduction to omega-3 and omega-6 fatty acids in neurological health and directions for future research
- Features novel focus on the adverse effects of omega-6 fatty acids on neurological function and the counterbalancing of dietary and tissue omega-6
- Illustrates the importance of omega-3 fatty acids in longevity and cognitive impairment
- Features new chapters on early effects in pregnancy and early infancy, animal model studies and autoimmune neurological diseases
- Discusses links between omega fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis, including the role of omega-3 fatty acid supplements
A. Omega Fatty acids and Brain: An overview
1. Essentiality of Omega3 Polyunsaturated Fatty Acids for Mammalian Brain
Development: A Translational Perspective
2. Thinking in polyunsaturated fatty acids, phospholipids and the brain
3. The Impact of Omega-3 Fatty Acids on Quality of Life
4. The Balance Between n-6 and n-3 and its Relation to Executive Function
5. Arachidonic Acid, Docosahexaenoic Acid, and Ethanol
B. Omega fatty acids: Brain and neurological development
6. Prenatal n-3 long-chain polyunsaturated fatty acids and childrens
executive functions
7. Omega-3 and Omega-6 fatty acid metabolism: Modeling growth and disease
using Caenorhabditis elegans
8. Fatty acids and the hippocampus
9. Energy metabolism of neural cells under the control of phospholipases A2
and docosahexaenoic acid
10. Omega-3 and Cognition in Children with Malnutrition
11. Neuroprotective effects of melatonin and omega-3 on the central nervous
system exposed to electromagnetic fields in the pre- and postnatal periods
12. Maternal omega 3 status: effects of cross-fostering on offspring brain
lipids and hippocampal neurogenesis
13. Linking omega-3 fatty acids and depression
14. Omega 3 Fatty Acids and the Cardiovascular System
C. Diet and Brain disease treatment and Prevention
15. Dietary Strategies and Supplements for the Prevention of Cognitive
Decline and Alzheimers disease
16. N-3 long chain PUFA-containing phospholipids and neuroprotection
17. Omega-3 Polyunsaturated Fatty Acid Supplementation as a Potential
Protective Factor or Treatment for Neurodegenerative Diseases
18. Neurobiological meaning of Omega-3 Fatty Acids and their potential role
in the treatment of schizophrenia
19. Neurodevelopmental and behavioral effects of variations in Omega-3
Polyunsaturated Fatty Acids levels in vulnerable populations
D. Nutrients and the Brain
20. Omega-3 fatty acids and cognitive behavior
21. Link between sugar intake and fatty acid metabolism in brain
22. N-3 and -6 fatty acids in fish: a focus on non-marine species
23. Aspartame Induced Neurodegeneration Versus Omega 3 Alleviation
24. DHA-enriched formulations as a promising strategy for the treatment of
hypoxic/ischemic brain injury
25. Alpha-linolenic acid and dementia in epidemiological studies
26. DHA a Key Supplement For Neurologic Health- An Insight
27. Obesity, Cognitive Functioning, and Dementia: A Lifespan Perspective
28. Fatty acids and brain health
29. Epigenetic effects of omega-3 fatty acids on neurons and astrocytes
during brain development and senescence
Ronald Ross Watson, PhD, is Professor of Health Promotion Sciences at the University of Arizona, Mel and Enid Zuckerman College of Public Health. Dr. Watson began his research in public health at the Harvard School of Public Health as a Fellow in 1971 doing field work on vaccines in Saudi Arabia. He has done clinical studies in Colombia, Iran, Egypt, Saudi Arabia and the United States which provides a broad international view of public health. He has served in the military reserve hospital for 17 years with extensive training in medical responses to disasters as the chief biochemistry officer of a general hospital, retiring as a Lt. Colonel. He is a distinguished member of several national and international nutrition, immunology, and cancer societies. Dr. Watsons career has involved studying many lifestyle aspects for their uses in health promotion. He has edited over 100 biomedical reference books and 450 papers and chapters. His teaching and research focuses on alcohol, tobacco, and drugs of abuse in heart function and disease in mouse models. Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRSC, FRCPath graduated with an Honours Degree in Biology and Physiology with Pharmacology. After gaining his University of London PhD, he received his Membership of the Royal College of Pathologists. He was later awarded his second doctorate (DSc), for his contribution to protein metabolism in health and disease. He is Professor of Clinical Biochemistry (Hon) at Kings College Hospital and Emeritus Professor of Nutritional Biochemistry at Kings College London. He has Honorary Professorships at the University of Hull, and the University of Suffolk. Professor Preedy was the Founding Director and then long-term Director of the Genomics Centre at Kings College London from 2006 to 2020. Professor Preedy has been awarded fellowships of the Royal Society of Biology, the Royal College of Pathologists, the Royal Society for the Promotion of Health, the Royal Institute of Public Health, the Royal Society for Public Health, the Royal Society of Chemistry and the Royal Society of Medicine. He carried out research when attached to the National Heart Hospital (part of Imperial College London), The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with international research groups in Finland, Japan, Australia, USA, and Germany. To his credit, Professor Preedy has published over 750 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and edited books.
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