Gastrointestinal sensory-motor dysfunction may cause acute, subacute, or chronic and variable digestive symptoms, and it may be overlooked as a factor across the cancer spectrum. The process may be regional or generalized, involving the entire gastrointestinal tract and it may be primary (a result of tumor-induced infiltrative denervation), or secondary to prior oncologic, surgical or radiation therapy. Sensory-motor dysfunction may precede, occur concurrently, or follow cancer, and it may be a manifestation of limited, metastatic, or even cured cancer. Clinical consideration and use of modern technology may help with diagnosis and therapy, thus improving quality of life in such patients.
This book compiles and presents the most clinically important issues in Onco-Neurogastroenterology to help anyone taking care of patients with cancer-related gastrointestinal problems.
Introduction to cancer and gastrointestinal motility and sensation.-
Symptom etiology.- Tests for gastrointestinal sensory-motor assessment:
Mouth, tongue, pharynx, hypopharynx, larynx, and upper esophageal sphincter.-
Tests for gastrointestinal sensory-motor assessment: Esophagus.- Tests for
gastrointestinal sensory-motor assessment: Stomach.- Tests for
gastrointestinal sensory-motor assessment: Biliary-Pancreas.- Tests for
gastrointestinal sensory-motor assessment: Small intestine.- Tests for
gastrointestinal sensory-motor assessment: Colo.- Tests for gastrointestinal
sensory-motor assessment: Ancillary tests.- Regional disorders of
sensory-motor dysfunction: Oropharynx, hypopharynx, and upper esophageal
sphincter.- Regional disorders of sensory-motor dysfunction: Esophagus.-
Regional disorders of sensory-motor dysfunction: Stomach.- Regional disorders
of sensory-motor dysfunction: Biliary-Pancreas.- Regional disorders of
sensory-motor dysfunction: Small intestine.- Regional disorders of
sensory-motor dysfunction: Colon and anorectum.- Multi-regional disorders.-
Pharmacotherapy of gastrointestinal sensory-motor disorders.- Common
therapies in Onco-neurogastroenterology.- Minimally invasive therapies for
gastrointestinal sensory-motor disorders.- Emergencies in
Onco-neurogastroenterology.- Nutritional issues.- Care coordination in
Onco-neurogastroenterology.- Illustrative cases in Onco-neurogastronterology.
George Triadafilopoulos, MD
UT MD Anderson Cancer Center
Section of Onco-Neurogastroenterology
Department of Gastroenterology, Hepatology and Nutrition
Houston, TX
David M. Richards, MD
UT MD Anderson Cancer Center
Section of Onco-Neurogastroenterology
Department of Gastroenterology, Hepatology and Nutrition
Houston, TX
Lavanya Viswanathan, MD, MS
UT MD Anderson Cancer Center
Section of Onco-Neurogastroenterology
Department of Gastroenterology, Hepatology and Nutrition
Houston, TX
