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Oxford Textbook of Clinical Nephrology 4th Revised edition [Multiple-component retail product]

Edited by (Professor of Nephrology, University of Edinburgh), Edited by , Edited by , Edited by (Professor, Cardiovascular and Cell Sciences Ins), Edited by , Edited by (Professor of Nephrology, University of Edinburgh, Edinburgh, UK), Edited by (Emeritus Professor of Medicine, University of Gent, Gent, Belgium)
  • Formatas: Multiple-component retail product, 3296 pages, aukštis x plotis x storis: 297x245x175 mm, weight: 8912 g
  • Serija: Oxford Textbook
  • Išleidimo metai: 29-Oct-2015
  • Leidėjas: Oxford University Press
  • ISBN-10: 0199592543
  • ISBN-13: 9780199592548
Kitos knygos pagal šią temą:
  • Formatas: Multiple-component retail product, 3296 pages, aukštis x plotis x storis: 297x245x175 mm, weight: 8912 g
  • Serija: Oxford Textbook
  • Išleidimo metai: 29-Oct-2015
  • Leidėjas: Oxford University Press
  • ISBN-10: 0199592543
  • ISBN-13: 9780199592548
Kitos knygos pagal šią temą:
This fourth edition of the Oxford Textbook of Clinical Nephrology builds on the success and international reputation of the publication as an important resource for the practising clinician in the field. It provides practical, scholarly, and evidence-based coverage of the full spectrum of clinical nephrology, written by a global faculty of experts.

The most relevant and important reference to clinical nephrology, this is an authoritative and comprehensive textbook combining the clinical aspects of renal disease essential to daily clinical practice with extensive information about the underlying basic science and current evidence available. Each section of the textbook has been critically and comprehensively edited under the auspices of a leading expert in the field.

This new edition has been significantly expanded and reapportioned to reflect developments and new approaches to topics, and includes treatment algorithms to aid and enhance patient care where possible. The fourth edition offers increased focus on the medical aspects of transplantation, HIV-associated renal disease, and infection and renal disease, alongside entirely new sections on genetic topics and clinical and physiological aspects of fluid/electrolyte and tubular disorders. The emphasis throughout is on marrying advances in scientific research with clinical management.

Richly illustrated throughout in full colour, this is a truly modern and attractive edition which reinforces the Oxford Textbook of Clinical Nephrology's position as an indispensable reference work of consistent quality and reliability. Enriched and refined by careful revision, this new edition continues the tradition of excellence.

This print edition of The Oxford Textbook of Clinical Nephrology comes with a year's access to the online version on Oxford Medicine Online. By activating your unique access code, you can read and annotate the full text online, follow links from the references to primary research materials, and view, enlarge and download all the figures and tables. Oxford Medicine Online is mobile optimized for access when and where you need it.

Recenzijos

Review from previous edition The Oxford Textbook of Clinical Nephrology is a core text for nephrologists and this third edition is no exception. With its international authorship and editorial panel this book represents the up-to-date opinion the evidence base of medicine for the renal patient... This is an excellent reference text for all nephrologists and a must for every medical library. * Hospital Doctor * A superb reference for nephrologists. Comprehensive, authoritative, well referenced and succinctly written text. Generously illustrated and delightfully bound in three volumes for the old fashioned reader with a CD-ROM of equal quality for the more modern. I would hate to be without it. * BMA Medical Book Competition 2006 *

Daugiau informacijos

Highly Commended in the Internal Medicine category of the British Medical Association Book Awards 2016.
Abbreviations xxiii
Contributors xxxi
VOLUME 1
SECTION 1 Assessment of the patient with renal disease
1 Epidemiology of kidney disease
3(17)
Aminu K. Bello
Marcello Tonelli
Kitty J. Jager
2 Clinical assessment of the patient with renal disease: overview
20(2)
Christopher G. Winearls
3 Presentations of renal disease
22(5)
Christopher G. Winearls
4 Kidney disease-focused history taking
27(2)
Christopher G. Winearls
5 Kidney disease-focused features on examination
29(6)
Christopher G. Winearls
6 Urinalysis
35(9)
Walter P. Mutter
7 Assessment of renal function
44(18)
Marijn Speeckaert
Joris Delanghe
8 Tubular function
62(4)
Marijn Speeckaert
Joris Delanghe
9 Renal radiology: overview
66(2)
Michael J. Weston
10 Ionizing radiation and radiation protection
68(6)
Jeannette Kathrin Kraft
Peter Howells
11 Plain radiography, excretion radiography, and contrast radiography
74(8)
Akira Kawashima
Andrew J. LeRoy
12 Intervention
82(7)
Steven Kennish
13 Ultrasound
89(12)
Toby Wells
Simon J. Freeman
14 Computed tomography
101(8)
Eugene Teoh
Michael J. Weston
15 Magnetic resonance imaging
109(8)
Kazuhiro Kitajima
Akira Kawashima
James F. Glockner
16 Radioisotopes in diagnostic imaging in nephrology
117(10)
Ramya Dhandapani
Sobhan Vinjamuri
17 Immunological investigation of the patient with renal disease
127(15)
Jo H. M. Berden
Jack F. M. Wetzels
18 The renal biopsy
142(19)
Ian S. D. Roberts
Philip Mason
Agnes B. Fogo
19 Clinical trials: why and how in nephrology
161(10)
Richard Haynes
Martin J. Landray
William G. Herrington
Colin Baigent
SECTION 2 The patient with fluid, electrolyte, and renal tubular disorders
20 An overview of tubular function
171(18)
Matthew A. Bailey
21 Sodium transport and balance: a key role for the distal nephron
189(8)
Laurent Schild
22 Water homeostasis
197(7)
David Marples
Søren Nielsen
23 Potassium homeostasis
204(14)
Alain Doucet
Gilles Crambert
24 Renal acid-base homeostasis
218(7)
Carsten A. Wagner
Olivier Devuyst
25 Phosphate homeostasis
225(6)
Heini Murer
Jurg Biber
Carsten A. Wagner
26 Calcium homeostasis
231(12)
Francesco Trepiccione
Giovambattista Capasso
27 Magnesium homeostasis
243(6)
Pascal Houillier
28 Approach to the patient with hyponatraemia
249(12)
Ewout J. Hoorn
Robert Zietse
29 Approach to the patient with hypernatraemia
261(11)
Robert Zietse
30 Approach to the patient with oedema
272(10)
Jean-Marie Krzesinski
Eric P. Cohen
31 Approach to the patient with salt-wasting tubulopathies
282(9)
Detlef Bockenhauer
Robert Kleta
32 Approach to the patient with polyuria
291(8)
Daniel G. Bichet
33 Clinical use of diuretics
299(24)
David H. Ellison
Arohan R. Subramanya
34 Approach to the patient with hypo-/hyperkalaemia
323(16)
Charles S. Wingo
I. David Weiner
35 Approach to the patient with metabolic acidosis or alkalosis
339(24)
Mitchell L. Halperin
Kamel S. Kamel
36 Approach to the patient with renal tubular acidosis
363(9)
Stephen B. Walsh
37 Approach to the patient with hypercalcaemia
372(6)
Dennis Joseph
Theresa A. Guise
38 Approach to the patient with hypocalcaemia
378(6)
Agnes Linglart
Anne-Sophie Lambert
39 Approach to the patient with hypo-/hyperphosphataemia
384(13)
Judith Blaine
Hector Giral
Sabina Jelen
Moshe Levi
40 Approach to the patient with hypomagnesaemia
397(15)
Martin Konrad
Karl P. Schlingmann
41 Approach to the patient with renal Fanconi syndrome, glycosuria, or aminoaciduria
412(13)
Detlef Bockenhauer
Robert Kleta
SECTION 3 The patient with glomerular disease
42 The glomerulus and the concept of glomerulonephritis
425(11)
Alexander Woywodt
Diana Chiu
43 The renal glomerulus: the structural basis of ultrafiltration
436(15)
Marlies Elger
Wilhelm Kriz
44 Function of the normal glomerulus
451(8)
Jean-Claude Dussaule
Martin Flamant
Christos Chatziantoniou
45 Mechanisms of glomerular injury: overview
459(4)
Neil Turner
46 The patient with haematuria
463(6)
John Neary
Neil Turner
47 Loin pain haematuria syndrome
469(4)
John Neary
48 Nutcracker syndrome and phenomenon
473(3)
John Neary
Neil Turner
49 Exercise-related pseudonephritis
476(2)
Neil Turner
50 Proteinuria
478(7)
Neil Turner
Stewart Cameron
51 Postural proteinuria (benign orthostatic proteinuria)
485(2)
Neil Turner
52 Nephrotic syndrome
487(9)
Premil Rajakrishna
Stewart Cameron
Neil Turner
53 Pathophysiology of oedema in nephrotic syndrome
496(3)
Neil Turner
Premil Rajakrishna
54 Idiopathic nephrotic syndrome: overview
499(2)
Patrick Niaudet
Alain Meyrier
55 Minimal change disease: clinical features and diagnosis
501(5)
Patrick Niaudet
Alain Meyrier
56 Minimal change disease: treatment and outcome
506(9)
Patrick Niaudet
Alain Meyrier
57 Primary focal segmental glomerulosclerosis: clinical features and diagnosis
515(10)
Alain Meyrier
Patrick Niaudet
58 Primary focal segmental glomerulosclerosis: treatment and outcome
525(8)
Alain Meyrier
Patrick Niaudet
59 Pathogenesis of proteinuria in minimal change disease and focal segmental glomerulosclerosis
533(4)
Patrick Niaudet
Alain Meyrier
60 Membranous glomerulonephritis: overview
537(2)
Daniel C. Cattran
Heather N. Reich
61 Membranous glomerulonephritis: clinical features and diagnosis
539(5)
Daniel C. Cattran
Heather N. Reich
62 Membranous glomerulonephritis: treatment and outcome
544(13)
Daniel C. Cattran
Heather N. Reich
63 Secondary membranous glomerulonephritis
557(3)
Daniel C. Cattran
Heather N. Reich
64 Membranous glomerulonephritis: pathogenesis
560(5)
Daniel C. Cattran
Heather N. Reich
65 Immunoglobulin A nephropathy: overview
565(1)
Kar Neng Lai
Sydney C. W. Tang
66 Immunoglobulin A nephropathy: clinical features
566(6)
Kar Neng Lai
Sydney C. W. Tang
67 Immunoglobulin A nephropathy: diagnosis
572(5)
Kar Neng Lai
Sydney C. W. Tang
68 Immunoglobulin A nephropathy: treatment and outcome
577(9)
Kar Neng Lai
Sydney C. W. Tang
69 Immunoglobulin A nephropathy: pathogenesis
586(6)
Kar Neng Lai
Sydney C. W. Tang
70 Crescentic (rapidly progressive) glomerulonephritis
592(6)
Neil Turner
71 Antiglomerular basement membrane disease: overview
598(1)
Zhao Cui
Neil Turner
Ming-Hui Zhao
72 Antiglomerular basement membrane disease: clinical features and diagnosis
599(7)
Zhao Cui
Neil Turner
Ming-Hui Zhao
73 Antiglomerular basement membrane disease: treatment and outcome
606(3)
Zhao Cui
Neil Turner
Ming-Hui Zhao
74 Antiglomerular basement membrane disease: pathogenesis
609(10)
Zhao Cui
Neil Turner
Ming-Hui Zhao
75 Alport post-transplant antiglomerular basement membrane disease
619(2)
Zhao Cui
Neil Turner
Ming-Hui Zhao
76 Post-infectious glomerulonephritis: overview
621(2)
Bernardo Rodriguez-Iturbe
Mark Haas
77 Post-streptococcal glomerulonephritis
623(10)
Bernardo Rodriguez-Iturbe
Mark Haas
78 Immunoglobulin A-dominant post-infectious glomerulonephritis
633(3)
Bernardo Rodriguez-Iturbe
Mark Haas
79 Glomerulonephritis associated with endocarditis, deep-seated infections, and shunt nephritis
636(5)
Bernardo Rodriguez-Iturbe
Mark Haas
80 Membranoproliferative glomerulonephritis and C3 glomerulopathy
641(8)
Daniel P. Gale
Terry Cook
81 Fibrillary and immunotactoid glomerulopathy
649(7)
Stephen M. Korbet
Melvin M. Schwartz
Edmund J. Lewis
82 Drug-induced and toxic glomerulopathies
656(13)
Alexander Woywodt
Diana Chiu
SECTION 4 The patient with interstitial disease
83 Acute tubulointerstitial nephritis: overview
669(9)
Richard Baker
84 Drug-induced acute tubulointerstitial nephritis
678(9)
Hassan Izzedine
Victor Gueutin
85 Other toxic acute tubulointerstitial nephritis
687(3)
Benjamin J. Freda
Gregory L. Braden
86 Chronic tubulointerstitial nephritis: overview
690(5)
Adalbert Schiller
Adrian Covic
Liviu Segall
87 Drug-induced chronic tubulointerstitial nephritis
695(7)
Hassan Izzedine
Victor Gueutin
88 Heavy metal-induced tubulointerstitial nephritis
702(7)
Patrick C. D'Haese
Benjamin A. Vervaet
Anja Verhulst
89 Aristolochic acid nephropathy caused by ingestion of herbal medicinal products
709(5)
M. Refik Gokmen
Graham M. Lord
90 Balkan endemic nephropathy
714(5)
Milan Radovic
Adalbert Schiller
91 Radiation nephropathy
719(5)
Lisa M. Phipps
David C. H. Harris
92 Urate nephropathy
724(2)
Duk-Hee Kang
Mehmet Kanbay
93 Immune-mediated tubulointerstitial nephritis
726(17)
Liviu Segall
Adrian Covic
SECTION 5 The patient with reduced renal function
94 Chronic kidney disease: definition, classification, and approach to management
743(12)
Ashish Upadhyay
Lesley A. Inker
Andrew S. Levey
95 Chronic kidney disease in the developed world
755(7)
Morgan E. Grams
Josef Coresh
96 Chronic kidney disease in developing countries
762(5)
Luxia Zhang
Haiyan Wang
97 Chronic kidney disease long-term outcomes: progression, death, cardiovascular disease, infections, and hospitalizations
767(10)
Monica Beaulieu
Catherine Weber
Nadia Zalunardo
Adeera Levin
98 Cardiovascular disease and chronic kidney disease: overview
777(3)
David J. Goldsmith
99 Recommendations for management of high renal risk chronic kidney disease
780(7)
Charles J. Ferro
Khai Ping Ng
100 Hypertension as a cause of chronic kidney disease: what is the evidence?
787(6)
Teena Tandon
Rajiv Agarwal
101 Diet and the progression of chronic kidney disease
793(7)
Juan Jesus Carrero
Hong Xu
Bengt Lindholm
102 Lipid disorders of patients with chronic kidney disease
800(7)
Alan G. Jardine
Rajan K. Patel
103 Smoking in chronic kidney disease
807(6)
Stephan R. Orth
104 Analytical aspects of measurements and laboratory values in kidney disease
813(11)
Edmund J. Lamb
Finlay MacKenzie
105 Effect of lifestyle modifications on patients with chronic kidney disease
824(6)
Andrew D. Williams
Robert G. Fassett
Erin J. Howden
Jeff S. Coombes
106 Malnutrition, obesity, and undernutrition in chronic kidney disease
830(7)
Navneet Kumar
Heather Henderson
Beverly D. Cameron
Peter A. McCullough
107 Left ventricular hypertrophy in chronic kidney disease
837(16)
Carmine Zoccali
Davide Bolignano
Francesca Mallamaci
108 Sudden cardiac death in chronic kidney disease
853(16)
Reza Hajhosseiny
Kaivan Khavandi
David J. Goldsmith
109 Epidemiology of calcium, phosphate, and parathyroid hormone disturbances in chronic kidney disease
869(8)
Patrick Biggar
Hansjorg Rothe
Markus Ketteler
110 The role of inflammation in chronic kidney disease
877(7)
Juan Jesus Carrero
Peter Stenvinkel
111 Vascular stiffness in chronic kidney disease: pathophysiology and implications
884(11)
Jonathan N. Townend
Charles J. Ferro
112 Oxidative stress and its implications in chronic kidney disease
895(8)
Nosratola D. Vaziri
113 Abnormal endothelial vasomotor and secretory function
903(7)
Thimoteus Speer
Danilo Fliser
114 Endothelins and their antagonists in chronic kidney disease
910(6)
Neeraj Dhaun
David J. Webb
115 Chronic kidney disease-mineral and bone disorder: overview
916(7)
Stuart M. Sprague
Menaka Sarav
116 Imaging for detection of vascular disease in chronic kidney disease patients
923(11)
Paolo Raggi
Luis D'Marco
117 Pathophysiology of chronic kidney disease-mineral and bone disorder
934(5)
Alexandra Voinescu
Nadia Wasi Iqbal
Kevin J. Martin
118 Management of chronic kidney disease-mineral and bone disorder
939(8)
Alexandra Voinescu
Nadia Wasi Iqbal
Kevin J. Martin
119 Fibroblast growth factor 23, Klotho, and phosphorus metabolism in chronic kidney disease
947(10)
Orlando M. Gutierrez
120 Vascular calcification
957(13)
Adrian Covic
Mugurel Apetrii
Luminita Voroneanu
David J. Goldsmith
121 Fractures in patients with chronic kidney disease
970(6)
Alastair J. Hutchison
Michael L. Picton
122 Spectrum of bone pathologies in chronic kidney disease
976(7)
Stuart M. Sprague
James M. Pullman
123 Clinical aspects and overview of renal anaemia
983(8)
Iain C. Macdougall
124 Erythropoiesis-stimulating agents in chronic kidney disease
991(7)
Iain C. Macdougall
125 Iron metabolism in chronic kidney disease
998(12)
Jolanta Malyszko
Iain C. Macdougall
126 Iron management in renal anaemia
1010(6)
Iain C. Macdougall
127 Pleiotropic effects of vitamin D
1016
Kaivan Khavandi
Halima Amer
Sarah Withers
Behdad Afzali
128 Immunity
1028(921)
Behdad Afzali
Claudia Kemper
129 The epidemiology of hepatitis viruses in chronic kidney disease
1049(3)
Fabrizio Fabrizi
Michel Jadoul
130 Gastroenterology and renal medicine
1052(12)
Rishi M. Goel
Kamal V. Patel
Terry Wong
131 Cutaneous manifestations of end-stage renal disease
1064(8)
Timur A. Galperin
Kieron S. Leslie
Antonia J. Cronin
132 The patient with reduced renal function: endocrinology
1072(19)
Tomas Thor Agustsson
Paul Carroll
133 Sexual dysfunction
1091(8)
Tomas Thor Agustsson
Paul Carroll
134 Health-related quality of life and the patient with chronic kidney disease
1099(3)
Fredric O. Finkelstein
Susan H. Finkelstein
135 Coagulopathies in chronic kidney disease
1102(3)
Seema Shrivastava
Beverley J. Hunt
Anthony Dorling
136 Mechanisms of progression of chronic kidney disease: overview
1105(2)
Neil Turner
137 Proteinuria as a direct cause of progression
1107(5)
Jeremy Hughes
138 Nephron numbers and hyperfiltration as drivers of progression
1112(6)
Valerie A. Luyckx
139 Podocyte loss as a common pathway to chronic kidney disease
1118(8)
Wilhelm Kriz
140 Disordered scarring and failure of repair
1126(10)
Jeremy S. Duffield
141 Modality selection for renal replacement therapy
1136(6)
Raj Thuraisingham
Cormac Breen
142 Patient education and involvement in pre-dialysis management
1142(6)
Sue Cox
Nicola Thomas
143 Preparation for renal replacement therapy
1148(9)
Muh Geot Wong
Bruce A. Cooper
Carol A. Pollock
144 Choices and considerations for in-centre versus home-based renal replacement therapy
1157(8)
Karthik K. Tennankore
Christopher T. Chan
145 Conservative care in advanced chronic kidney disease
1165(15)
Aine Burns
Fliss E. M. Murtagh
146 Palliative care in end-stage renal disease
1180(7)
Katie Vinen
Fliss E. M. Murtagh
Irene J. Higginson
147 Patient selection when resources are limited
1187(5)
Bernadette A. Thomas
Christopher R. Blagg
148 Acidosis in chronic kidney disease
1192(7)
Muhammad M. Yaqoob
Index
VOLUME 2
SECTION 6 The patient with another primary diagnosis
149 The patient with diabetes mellitus
1199(49)
Luigi Gnudi
Giorgio Gentile
Piero Ruggenenti
150 Kidney involvement in plasma cell dyscrasias
1248(3)
Pierre M. Ronco
151 The patient with cryoglobulinaemia
1251(13)
Fabrizio Fabrizi
Patrice Cacoub
152 The patient with amyloidosis
1264(12)
Helen J. Lachmann
Giampaolo Merlini
153 The patient with myeloma
1276(16)
Efstathios Kastritis
Meletios A. Dimopoulos
154 Light-chain deposition disease
1292(7)
Dirk R. J. Kuypers
Morie A. Gertz
155 Other consequences from monoclonal immunoglobulins/fragments: membranoproliferative glomerulonephritis and acquired Fanconi syndrome
1299(5)
Fernando C. Fervenza
S. Vincent Rajkumar
Sanjeev Sethi
156 The patient with sarcoidosis
1304(3)
Ravindra Rajakariar
Muhammad M. Yaqoob
157 The patient with vasculitis: overview
1307(8)
David Jayne
158 The patient with vasculitis: pathogenesis
1315(17)
Peter Heeringa
Coen A. Stegeman
159 The patient with vasculitis: clinical aspects
1332(12)
Alan D. Salama
160 The patient with vasculitis: treatment and outcome
1344(12)
Lorraine Harper
David Jayne
161 The patient with systemic lupus erythematosus: overview and pathogenesis
1356(9)
Johan van der Viag
Jo H. M. Berden
162 The patient with systemic lupus erythematosus: clinical features, investigations, and diagnosis
1365(15)
Marie Condon
Philippa Dodd
Liz Lightstone
163 The patient with systemic lupus erythematosus: treatment and outcome
1380(9)
Frederic A. Houssiau
164 The patient with antiphospholipid syndrome with or without lupus
1389(6)
Bassam Alchi
David Jayne
165 The patient with scleroderma: systemic sclerosis
1395(8)
Bernadette Lynch
Aine Burns
166 The patient with rheumatoid arthritis, mixed connective tissue disease, Sjogren syndrome, or polymyositis
1403(10)
Lesley-Anne Bissell
Dwomoa Adu
Paul Emery
167 The patient with sickle cell anaemia
1413(11)
Jean-Philippe Haymann
Francois Lionnet
168 The obese patient (metabolic syndrome)
1424(9)
Maarit Korkeila
Bengt Lindholm
Peter Stenvinkel
169 The patient with hepatorenal syndrome
1433(9)
Andres Cardenas
Pere Gines
170 Kidney/ear syndromes
1442(8)
Paul Goodyer
171 Kidney/eye syndromes
1450(7)
Friederike Mackensen
Vedat Schwenger
Heiko Billing
172 The patient with renal cell cancer
1457(7)
Tim Eisen
173 The patient with Wilms tumour
1464(5)
Christopher Mitchell
174 The patient with haemolytic uraemic syndrome/thrombotic thrombocytopenic purpura
1469(24)
Marina Noris
Tim Goodship
SECTION 7 The patient with urinary tract infection
175 Urinary tract infection in the adult: overview
1493(2)
Neil Sheerin
176 Infection of the lower urinary tract
1495(11)
Ased Ali
Rob Pickard
177 Upper urinary tract infection
1506(8)
Mark Harber
178 Complicated urinary tract infection
1514(3)
Ased Ali
Rob Pickard
179 Urinary tract infection in a patient with a kidney transplant
1517(3)
Mark Harber
180 Urinary tract infection in infancy and childhood
1520(12)
Heather Lambert
181 Schistosomiasis: the parasite and the host
1532(6)
Rashad S. Barsoum
182 Schistosomiasis: clinical impact
1538(7)
Rashad S. Barsoum
SECTION 8 The patient with infections causing renal disease
183 Malaria
1545(5)
Vinay Sakhuja
Harbir Singh Kohli
184 Leishmaniasis and trypanosomiasis
1550(2)
Vinay Sakhuja
Harbir Singh Kohli
185 Hepatitis B
1552(8)
Marion Muche
Seema Baid-Agrawal
186 Hepatitis C
1560(7)
Fabrizio Fabrizi
187 HIV and renal disease
1567(9)
Saraladevi Naicker
Graham Paget
188 Hantaviral infections
1576(5)
Jan Clement
Jung-San Chang
Hung-Chun Chen
Piet Maes
189 Dengue and other viral haemorrhagic fevers
1581(3)
Jung-San Chang
Hung-Chun Chen
190 Yellow fever, severe acute respiratory syndrome virus, and H1N1 influenza infections
1584(3)
Norbert Lameire
191 Leptospirosis
1587(3)
Emmanuel A. Burdmann
192 Syphilis
1590(2)
Emmanuel A. Burdmann
193 Rickettsiosis
1592(4)
Emmanuel A. Burdmann
Vivekanand Jha
194 Schistosomiasis
1596(6)
Rashad S. Barsoum
195 Nematode infections
1602(2)
Raja Ramachandran
Vivekanand Jha
196 Mycobacterial infections: tuberculosis
1604(16)
John Eastwood
Cathy Corbishley
John Grange
197 Mycobacterial infections: leprosy and environmental mycobacteria
1620(5)
John Eastwood
Cathy Corbishley
John Grange
198 Renal involvement in other infections: diarrhoeal diseases, salmonella, melioidosis, and pregnancy
1625(6)
Raja Ramachandran
Vivekanand Jha
SECTION 9 The patient with urinary stone disease
199 Epidemiology of nephrolithiasis
1631(6)
Eric N. Taylor
Gary C. Curhan
200 Approach to the patient with kidney stones
1637(8)
Bhavna Chopra
Stanley Goldfarb
201 Calcium stones
1645(16)
David A. Bushinsky
Orson Moe
202 Uric acid stones
1661(5)
Michel Daudon
Paul Jungers
203 Cystine stones
1666(5)
Michel Daudon
Paul Jungers
204 Cell biology of nephrocalcinosis/nephrolithiasis
1671(26)
Benjamin A. Vervaet
Marc E. De Broe
205 Medical management of nephrocalcinosis and nephrolithiasis
1697(16)
Bridget Sinnott
Naim Maalouf
Khashayar Sakhaee
Orson W. Moe
206 Imaging and interventional treatment: urolithiasis from the surgeon's point of view
1713(12)
Gauthier Raynal
Olivier Traxer
SECTION 10 The patient with hypertension
207 The structure and function of renal blood vessels
1725(4)
Karlhans Endlich
Rodger Loutzenhiser
208 Regulation of vasomotor tone in the afferent and efferent arterioles
1729(9)
Karlhans Endlich
Rodger Loutzenhiser
209 Tubuloglomerular feedback, renal autoregulation, and renal protection
1738(4)
Karlhans Endlich
Rodger Loutzenhiser
210 The kidney and control of blood pressure
1742(8)
Olga Gonzalez-Albarran
Luis M. Ruilope
211 The effect of hypertension on renal vasculature and structure
1750(10)
Ulrich Wenzel
Thorsten Wiech
Udo Helmchen
212 Ischaemic nephropathy
1760(6)
Helen Alderson
Constantina Chrysochou
James Ritchie
Philip A. Kalra
213 Renal artery stenosis: clinical features and diagnosis
1766(10)
James Ritchie
Darren Green
Constantina Chrysochou
Philip A. Kalra
214 Renal artery stenosis: diagnosis
1776(6)
James Ritchie
Darren Green
Constantina Chrysochou
Philip A. Kalra
215 Renal artery stenosis: management and outcome
1782(10)
James Ritchie
Darren Green
Constantina Chrysochou
Philip A. Kalra
216 Malignant hypertension
1792(7)
Caroline Whitworth
Stewart Fleming
217 Resistant hypertension
1799(3)
Iain M. MacIntyre
David J. Webb
218 The hypertensive child
1802(23)
Wolfgang Rascher
219 Treatment of hypertension in children
1825(6)
Wolfgang Rascher
SECTION 11 The patient with acute kidney injury (and critical care nephrology)
220 Definitions, classification, epidemiology, and risk factors of acute kidney injury
1831(13)
Eric A. J. Hoste
John A. Kellum
221 Pathophysiology of acute kidney injury
1844(28)
Michael S. Goligorsky
Julien Maizel
Radovan Vasko
May M. Rabadi
Brian B. Ratliff
222 Clinical approach to the patient with acute kidney injury: diagnosis and differential diagnosis
1872(15)
Norbert Lameire
Raymond Vanholder
Wim Van Biesen
223 The role of novel biomarkers in acute kidney injury
1887(9)
Norbert Lameire
224 Prevention of acute kidney injury: overview
1896(6)
Norbert Lameire
225 Prevention of acute kidney injury: non-pharmacological strategies
1902(13)
Norbert Lameire
226 Prevention of acute kidney injury: pharmacological strategies
1915(10)
Norbert Lameire
227 Prevention of acute kidney injury: drug- and nephrotoxin-induced acute kidney injury
1925(8)
Norbert Lameire
228 Non-dialytic management of the patient with acute kidney injury
1933(8)
Achim Jorres
Dietrich Hasper
Michael Oppert
229 Fluid overload in acute kidney injury
1941(4)
Achim Jorres
Dietrich Hasper
Michael Oppert
230 Electrolyte and acid--base disorders in AKI
1945(9)
Achim Jorres
Dietrich Hasper
Michael Oppert
231 Coagulation disturbances in acute kidney injury
1954(2)
Achim Jorres
Dietrich Hasper
Michael Oppert
232 Renal replacement therapy in the patient with acute kidney injury: overview
1956(6)
Jang Won Seo
Ravindra L. Mehta
233 Intermittent acute renal replacement therapy
1962(13)
Mark R. Marshall
234 Continuous renal replacement therapy
1975(14)
Miet Schetz
Andrew Davenport
235 Peritoneal dialysis in acute kidney injury
1989(9)
Wim Van Biesen
236 Scoring systems in acute kidney injury patients
1998(11)
Angel Candela-Toha
Teresa Tenorio
Aurora Lietor
Fernando Liano
237 Overall outcomes of acute kidney injury
2009(8)
Norbert Lameire
Wim Van Biesen
Raymond Vanholder
238 Renal outcomes of acute kidney injury
2017(7)
Norbert Lameire
239 Acute kidney injury in children
2024(14)
Alexander Fichtner
Franz Schaefer
240 Acute kidney injury in the elderly
2038(9)
Dinna N. Cruz
Anna Clementi
Mitchell H. Rosner
241 Acute kidney injury in the tropics
2047(12)
Vivekanand Jha
242 Acute kidney injury and hantavirus disease
2059(8)
Jan Clement
243 Community-acquired pneumonia and acute kidney injury
2067(1)
Norbert Lameire
244 Acute kidney injury in severe sepsis
2068(8)
John Prowle
Rinaldo Bellomo
245 Cardiovascular surgery and acute kidney injury
2076(8)
Jeremiah R. Brown
Chirag R. Parikh
246 Contrast-induced acute kidney injury
2084(7)
Douglas Stewart
Gaurav Shah
Jeremiah R. Brown
Peter A. McCullough
247 Renal failure in cirrhosis: pathogenesis, diagnosis, and treatment
2091(18)
Vicente Arroyo
Monica Guevara
Javier Fernandez
248 Acute kidney injury in heart failure
2109(6)
Dinna N. Cruz
Anna Giuliani
Claudio Ronco
249 Acute kidney injury in pulmonary diseases
2115(14)
Soo Young Yoon
Ravindra L. Mehta
250 Acute kidney injury in pregnancy
2129(4)
Duska Dragun
Bjorn Hegner
251 Acute kidney injury in the cancer patient
2133(10)
Gilbert W. Moeckel
Veena Manjunath
Mark A. Perazella
252 Acute kidney injury in polytrauma and rhabdomyolysis
2143(8)
Mehmet Sukru Sever
Raymond Vanholder
253 Acute kidney injury in patients with severe burn injury
2151(10)
Nele Brusselaers
Eric A. J. Hoste
Index
VOLUME 3
SECTION 12 The patient on dialysis
254 Uraemic toxins: overview
2161(12)
Griet Glorieux
Nathalie Neirynck
Anneleen Pletinck
Eva Schepers
Raymond Vanholder
255 Haemodialysis: overview
2173(3)
Jonathan Himmelfarb
256 Haemodialysis: vascular access
2176(12)
Michael Allon
257 Haemodialysis: principles
2188(11)
Claudio Ronco
William R. Clark
258 Haemodialysis: prescription and assessment of adequacy
2199(19)
Scott D. Bieber
Jonathan Himmelfarb
259 Haemodialysis: acute complications
2218(11)
Victor F. Seabra
Bertrand L. Jaber
260 Haemohitration and haemodiafiltration
2229(9)
Francesco Locatelli
Celestina Manzoni
Giuseppe Pontoriero
Salvatore Di Filippo
261 Dialysis withdrawal and palliative care
2238(7)
Arkadiy Plnkhasov
Michael J. Germain
Lewis M. Cohen
262 Frequent haemodialysis
2245(15)
Alan S. Kllger
Rita Suri
263 Peritoneal dialysis: overview
2260(3)
Rajnish Mehrotra
Jonathan Himmelfarb
264 Peritoneal dialysis: principles and peritoneal physiology
2263(11)
Joanna Stachowska-Pietka
Jacek Waniewski
Bengt Lindholm
265 Peritoneal dialysis: adequacy and prescription management
2274(7)
Anjali Bhatt Saxena
266 Peritoneal dialysis: non-infectious complications
2281(9)
Sara Dunsmore
Joanne M. Bargman
267 Overview of dialysis patient management and future directions
2290(6)
Allen R. Nissenson
John Moran
Robert Provenzano
268 Cardiovascular complications in end-stage renal disease patients: pathophysiological aspects
2296(8)
Gerard M. London
269 Bacterial and fungal infections in patients on haemodialysis
2304(6)
Laura Labriola
Eric Goffin
Michel Jadoul
270 Bacterial and fungal infections in patients on peritoneal dialysis
2310(4)
Eric Goffin
Laura Labriola
Michel Jadoul
271 Viral infections in patients on dialysis
2314(2)
Michel Jadoul
Laura Labriola
Eric Goffin
272 Cognitive function, depression, and psychosocial adaptation
2316(8)
Manjula Kurella Tamura
Mark L. Unruh
Ea Wha Kang
273 Volume assessment and management in dialysis
2324(10)
Rajiv Agarwal
274 Nutritional screening and nutritional management in dialysis patients
2334(11)
Carla Maria Avesani
Juan Jesus Carrero
Bengt Lindholm
Peter Stenvinkel
SECTION 13 The transplant patient
275 The evolution of kidney transplantation
2345(13)
Peter J. Morris
Jeremy R. Chapman
276 Pre-transplant assessment of the recipient
2358(8)
Christophe Legendre
277 Organ donation
2366(12)
Thomas Mone
278 Donor and recipient kidney transplantation surgery
2378(12)
Richard D. M. Allen
Henry C. C. Pleass
279 Immunology, sensitization, and histocompatibility
2390(15)
Thangamani Muthukumar
Darshana Dadhania
Choli Hartono
Manikkam Suthanthiran
280 Immediate post-transplant care and surgical complications
2405(8)
Simon R. Knight
Rutger J. Ploeg
281 Immunosuppression: drugs and protocols
2413(13)
Dirk R.J. Kuypers
Maarten Naesens
282 Renal transplant imaging
2426(15)
Simon Gruenewald
Philip Vladica
283 Rejection
2441(12)
David N. Rush
Peter W. Nickerson
284 Infection: prophylaxis, diagnosis, and management
2453(10)
Camille Nelson Kotton
285 Cardiovascular disease: prophylaxis, diagnosis, and management
2463(8)
Emily P. McQuarrie
Hallvard Holdaas
Bengt Fellstrom
Alan G. Jardine
286 Chronic allograft dysfunction
2471(12)
Lorna K. Henderson
Brian J. Nankivell
Jeremy R. Chapman
287 Cancer after kidney transplantation
2483(8)
Germaine Wong
Angela C. Webster
288 Metabolic bone disease after renal transplantation
2491(11)
Grahame J. Elder
289 Recurrent renal disease: prophylaxis, diagnosis, and management
2502(7)
Philip Clayton
Steven Chadban
290 Paediatric renal transplantation
2509(12)
Minnie M. Sarwal
Ron Shapiro
SECTION 14 Renal disease at different stages of life (infancy, adolescence, pregnancy, old age)
291 Growth and development
2521(6)
Lesley Rees
292 The adolescent with renal disease: transition to adult services
2527(3)
Stephen D. Marks
293 Contraception in patients with kidney disease
2530(7)
Kate Wiles
Catherine Nelson-Piercy
294 Pregnancy and renal physiology
2537(12)
Kate Bramham
Catherine Nelson-Piercy
295 Pregnancy in patients with chronic kidney disease and on dialysis
2549(7)
Kate Bramham
Catherine Nelson-Piercy
296 Pre-eclampsia and related disorders
2556(10)
Kate Wiles
Catherine Nelson-Piercy
297 Acute kidney injury in pregnancy
2566(4)
Kate Wiles
Catherine Nelson-Piercy
298 Specific renal conditions in pregnancy
2570(7)
Kate Bramham
Catherine Nelson-Piercy
299 Pregnancy after renal transplantation
2577(3)
Kate Bramham
Catherine Nelson-Piercy
300 The kidney in ageing: biology, anatomy, physiology, and clinical relevance
2580(11)
Richard J. Glassock
Andrew D. Rule
SECTION 15 The patient with genetic renal disease
301 Ethical aspects of genetic testing
2591(3)
Frances Flinter
302 Antenatal diagnosis and pre-implantation genetic testing
2594(3)
Frances Flinter
303 The molecular basis of ciliopathies and cyst formation
2597(20)
Wolfgang Kuhn
Gerd Walz
304 The adult with renal cysts
2617(4)
Yves Pirson
Olivier Devuyst
305 The child with renal cysts
2621(4)
Carsten Bergmann
Nadina Ortiz-Bruchle
Valeska Frank
Klaus Zerres
306 Autosomal dominant polycystic kidney disease: overview
2625(2)
Albert C. M. Ong
Richard Sandford
307 Autosomal dominant polycystic kidney disease: clinical features
2627(7)
Albert C. M. Ong
Timothy Ellam
308 Autosomal dominant polycystic kidney disease: diagnosis
2634(4)
Richard Sandford
309 Autosomal dominant polycystic kidney disease: management
2638(9)
Young-Hwan Hwang
York Pei
310 Management of intracranial aneurysms
2647(2)
Yves Pirson
Dominique Chauveau
311 Management of cystic liver disease
2649(4)
Tom J. G. Gevers
Joost P. H. Drenth
312 Autosomal dominant polycystic kidney disease in children and young adults
2653(3)
Carsten Bergmann
Klaus Zerres
313 Autosomal recessive polycystic kidney disease
2656(9)
Carsten Bergmann
Klaus Zerres
314 Bardet--Biedl syndrome and other ciliopathies
2665(6)
Lukas Foggensteiner
Philip Beales
315 Hepatocyte nuclear factor-1B
2671(3)
Coralie Bingham
316 Nephronophthisis and medullary cystic kidney disease: overview
2674(3)
John A. Sayer
317 Nephronophthisis
2677(5)
John A. Sayer
Roslyn J. Simms
318 Autosomal dominant interstitial kidney disease including medullary cystic disease
2682(3)
John A. Sayer
319 Oral-facial-digital type 1 syndrome
2685(3)
Brunella Franco
320 The molecular basis of glomerular basement membrane disorders
2688(7)
Rachel Lennon
Nell Turner
321 Alport syndrome: overview
2695(2)
Laurence Heldet
Bertrand Knebelmann
Marie Claire Gubler
322 Alport syndrome: clinical features
2697(3)
Laurence Heidet
Bertrand Knebelmann
Marie Claire Gubler
323 Alport syndrome: diagnosis
2700(6)
Laurence Heidet
Bertrand Knebelmann
Marie Claire Gubler
324 Alport syndrome: management
2706(3)
Laurence Heidet
Bertrand Knebelmann
Marie Claire Gubler
325 Thin glomerular basement membrane nephropathy and other collagenopathies
2709(2)
Laurence Heidet
Bertrand Knebelmann
Marie Claire Gubler
326 Nail patella syndrome
2711(3)
Laurence Heidet
Marie Claire Gubler
327 Molecular basis of nephrotic syndrome
2714(8)
Moin A. Saleem
Corinne Antignac
328 Molecular basis of renal tumour syndromes
2722(5)
Thomas Connor
Patrick H. Maxwell
329 WT1 and its disorders
2727(5)
Nick Hastie
Eve Miller-Hodges
330 Tuberous sclerosis complex renal disease
2732(7)
Bradley P. Dixon
J. Christopher Kingswood
John J. Bissler
331 Hypoxia-inducible factor and renal disorders
2739(4)
Thomas Connor
Patrick H. Maxwell
332 Von Hippel--Lindau disease
2743(4)
Thomas Connor
Patrick H. Maxwell
333 Molecular basis of complement-mediated renal disease
2747(10)
Nicholas Medjeral-Thomas
Anna Richards
Matthew C. Pickering
334 Inherited metabolic diseases and the kidney
2757(10)
Robin Lachmann
Elaine Murphy
335 Fabry disease: overview and pathophysiology
2767(3)
Stephen Waldek
336 Fabry disease: clinical features
2770(6)
Stephen Waldek
337 Fabry disease: diagnosis
2776(4)
Stephen Waldek
338 Fabry disease: management and outcome
2780(9)
Stephen Waldek
339 Cystinosis
2789(9)
Elena N. Levtchenko
Mirian C. Janssen
340 Mitochondrial diseases and the kidney
2798(10)
Andrew Hall
Shamima Rahman
341 APOL1 and renal disease
2808(3)
Neil Turner
Teena Tandon
Rajiv Agarwal
342 MYH9 and renal disease
2811(4)
Neil Turner
Bertrand Knebelmann
SECTION 16 The patient with structural and congenital abnormalities
343 Human kidney development
2815(7)
Paul Winyard
344 Kidney stem cells
2822(6)
Oren Pleniceanu
Benjamin Dekel
345 Anatomical types of congenital anomalies: overview of obstruction
2828(2)
Michiel F. Schreuder
346 Renal agenesis
2830(1)
Michiel F. Schreuder
347 Renal dysplasia
2831(1)
Michiel F. Schreuder
348 Renal hypoplasia
2832(1)
Michiel F. Schreuder
349 Normal variation in nephron numbers
2833(2)
Michiel F. Schreuder
350 Renal tubular dysgenesis
2835(1)
Michiel F. Schreuder
351 Congenital solitary functioning kidney
2836(2)
Michiel F. Schreuder
352 Duplex, ectopic, and horseshoe kidneys
2838(2)
Michiel F. Schreuder
353 Pelviureteric junction obstruction and megaureter in children
2840(2)
Michiel F. Schreuder
354 Posterior urethral valves
2842(2)
Michiel F. Schreuder
355 Primary vesicoureteric reflux and reflux nephropathy
2844(10)
Heather Lambert
356 The patient with urinary tract obstruction
2854(7)
Muhammad M. Yaqoob
Katherine Bennett-Richards
Islam Junaid
357 Retroperitoneal fibrosis
2861(4)
Muhammad M. Yaqoob
Katherine Bennett-Richards
Islam Junaid
358 Branchio-oto-renal syndrome
2865(2)
Udo Vester
Stefanie Weber
359 Townes-Brocks syndrome
2867(2)
Udo Vester
Stefanie Weber
360 Renal coloboma syndrome
2869(2)
Udo Vester
Stefanie Weber
361 Ante- and postnatal imaging to diagnose human kidney malformations
2871(14)
Fred E. Avni
Marie Cassart
Anne Massez
Michele Hall
SECTION 17 Drugs and renal disease
362 Drug-induced nephropathies
2885(26)
Anushree Shirali
Mark A. Perazella
363 Drug dosing in chronic kidney disease
2911(8)
Ali J. Olyaei
Ted A. Foster
Edgar V. Lerma
364 Drug dosing in acute kidney injury
2919
Thomas A. Golper
Andrew A. Udy
Jeffrey Lipman
SECTION 18 Nephrology in the future
365 A global curriculum for training the next generation of nephrologists
Tushar J. Vachharajani
Richard K. S. Phoon
David C. H. Harris
Index
Neil Turner has been Professor of Nephrology at the University of Edinburgh since 1998. After broad experience of general medicine he worked in renal units in Oxford, Hammersmith, and Aberdeen before moving to Edinburgh. His major research and clinical interests are currently in genetic diseases of the glomerular basement membrane, and in paediatric-adult transition. Professor Turner is involved in international educational activities through both Edinburgh University and the International Society of Nephrology.



Professor Goldsmith is a Consultant Nephrologist at Guys and St Thomas' Hospitals; Professor, Cardiovascular and Cell Sciences Institute, St Georges University of London; and Professor of Nephrology in Gr. T. Popa University of Medicine and Pharmacy, Romania. He is also Clinical Director of the NIHR South London Clinical Research Network. He is a Fellow of both the American Society of Nephrology and also the European Renal Association-EDTA. He was Co-Editor of the Journal of Nephrology (2006-2009), and was Associate Editor of CJASN (2010-2014). He is the Associate Editor of International Journal of Clinical Practice (2014 -), and on the Editorial Boards of Nephrology, Dialysis and Transplantation, CJASN, CardioRenal Medicine, and International Urology and Nephrology.



Dr. Jonathan Himmelfarb is Director of the Kidney Research Institute, Professor of Medicine, and holds the Joseph W. Eschbach M.D. Endowed Chair in Kidney Research at the University of Washington. He is also President-elect of the American Society of Nephrology (ASN) in 2014-2015. He has served on numerous editorial boards, including the Journal of the American Society of Nephrology, Clinical Journal of the American Society of Nephrology, Kidney International, Faculty of 1000 in Medicine, and the Faculty of 1000 in Research. Current research interests include studies on a wearable artificial kidney; development of a human 'kidney-on-a-chip', and development and evaluation of risk biomarkers in acute and chronic kidney disease.



Dr Chris Winearls graduated from the University of Cape Town in 1973. He completed a PhD in transplant immunology at Oxford University before training in nephrology at the Royal Postgraduate Medical School and the Hammersmith Hospital, London, where he was part of the team that investigated the first clinical use of recombinant human erythropoietin. He was appointed consultant nephrologist in Oxford in 1988 and was Clinical Director 1995 to 2009. Dr Winearls is currently a Fellow of Jesus College Oxford and an Hon Senior Lecturer in Medicine at the University of Oxford. His research interests include paraprotein disorders affecting the kidney, ADPKD, The CKD construct and renal anaemia.

With expert input from section editors William G. Bennett, Marc E. De Broe, Jeremy R. Chapman, Adrian Covic, Vivekanand Jha, Neil Sheerin, Robert Unwin and Adrian Woolf