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ix | |
Preface |
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xi | |
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PART I INTRODUCTION AND CONCEPTS |
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1 An Introduction To The Development Of Palaeopathology |
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3 | (20) |
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3 | (2) |
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5 | (1) |
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6 | (2) |
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1.4 And So, Back to Esper |
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8 | (1) |
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1.5 An Obsession with Skulls |
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9 | (7) |
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1.6 The First Palaeopathologist |
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16 | (4) |
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1.7 Post-Bellum Developments |
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20 | (3) |
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23 | (24) |
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2.1 The Response to Pathological Stimuli |
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23 | (3) |
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2.2 Bone Cells and Cytokines |
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26 | (6) |
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32 | (1) |
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2.4 Bone Metabolism and the Bone Remodelling Unit |
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32 | (3) |
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2.5 Pathological Mechanisms |
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35 | (2) |
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2.6 The Antiquity of Bone |
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37 | (1) |
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2.7 The Stability of Reaction to Pathological Insults |
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38 | (2) |
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2.8 The Expression of Disease |
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40 | (4) |
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2.9 Pathology, Pseudo-Pathology and Normal Variation |
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44 | (3) |
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47 | (13) |
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47 | (1) |
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3.2 Some Theories of Health |
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48 | (4) |
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52 | (3) |
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3.4 A Model of Health and Disease (and Some Definitions) |
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55 | (3) |
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3.5 The Consequences for Palaeopathology |
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58 | (2) |
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60 | (13) |
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4.1 Diagnosis in the Past |
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62 | (1) |
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4.2 Diagnosis in Modern Clinical Practice |
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63 | (3) |
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4.3 Diagnosis in Paleopathology |
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66 | (7) |
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5 Joint Diseases 1: Osteoarthritis |
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73 | (23) |
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76 | (2) |
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5.2 Precipitants of Osteoarthritis |
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78 | (2) |
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5.3 Other Types of Osteoarthritis |
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80 | (2) |
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5.4 The Natural History of Osteoarthritis |
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82 | (2) |
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5.5 Diagnosis of Osteoarthritis |
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84 | (1) |
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5.6 Osteoarthritis at Individual Sites |
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85 | (6) |
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5.7 The Association between Osteoarthritis and Some Other Conditions |
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91 | (3) |
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5.8 Osteoarthritis in Animals |
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94 | (2) |
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6 Joint Diseases 2: The Erosive Arthropathies |
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96 | (29) |
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96 | (3) |
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6.2 The Pathophysiology of Rheumatoid Arthritis |
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99 | (4) |
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6.3 Seronegative Arthropathies |
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103 | (1) |
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6.4 Erosive Osteoarthritis |
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103 | (3) |
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6.5 The Spondyloarthritides |
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106 | (1) |
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6.6 Ankylosing Spondylitis |
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107 | (4) |
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6.7 Reactive Spondyloarthropathy (Reiter's Syndrome) |
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111 | (3) |
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6.8 Psoriatic Arthropathy |
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114 | (2) |
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6.9 Enteropathic Arthropathy |
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116 | (1) |
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6.10 Undifferentiated Spondyloarthritides |
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117 | (1) |
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118 | (1) |
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6.12 Gout and Other Crystal Arthropathies |
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118 | (4) |
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6.13 Other Crystal Arthropathies |
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122 | (1) |
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122 | (3) |
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125 | (22) |
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7.1 Intervertebral Disc Disease (IVD) |
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125 | (3) |
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128 | (1) |
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7.3 Ossification of the Ligamentum Flavum |
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129 | (1) |
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7.4 Diffuse Idiopathic Skeletal Hyperostosis |
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129 | (5) |
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7.5 Ossification in the Posterior Longitudinal Ligament |
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134 | (1) |
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7.6 Kyphosis and Scoliosis |
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135 | (4) |
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7.7 Klippel--Feil Syndrome |
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139 | (1) |
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7.8 Spondylolysis and Spondylolisthesis |
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140 | (2) |
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142 | (1) |
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7.10 Other Spinal Anomalies |
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143 | (4) |
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147 | (41) |
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148 | (3) |
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8.2 Special Forms of Osteomyelitis |
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151 | (3) |
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154 | (8) |
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162 | (5) |
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167 | (2) |
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8.6 The Origins of Syphilis |
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169 | (2) |
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8.7 Changes in the Skeleton |
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171 | (3) |
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174 | (1) |
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175 | (1) |
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8.10 Fungal Infections of Bone |
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176 | (1) |
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176 | (3) |
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8.12 Non-specific Infections |
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179 | (9) |
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188 | (20) |
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188 | (5) |
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9.2 Paget's Disease of Bone (PDB) |
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193 | (5) |
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9.3 Rickets and Osteomalacia |
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198 | (3) |
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201 | (1) |
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202 | (3) |
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9.6 Other Metabolic Diseases |
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205 | (3) |
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208 | (27) |
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10.1 Fractures and Dislocations |
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208 | (2) |
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210 | (11) |
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10.3 Dislocations and Subluxations |
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221 | (2) |
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223 | (2) |
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225 | (3) |
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228 | (1) |
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229 | (3) |
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232 | (3) |
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235 | (27) |
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11.1 Epidemiology of Bone Tumours |
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235 | (2) |
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237 | (10) |
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247 | (7) |
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11.4 Metastatic Bone Tumours |
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254 | (8) |
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12 Disorders Of Growth And Development |
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262 | (30) |
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262 | (4) |
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12.2 Abnormal Growth and Development |
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266 | (1) |
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266 | (12) |
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278 | (1) |
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12.5 Disorders of Skull Growth |
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279 | (3) |
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12.6 Developmental Disorders of the Hips |
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282 | (3) |
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285 | (4) |
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289 | (1) |
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289 | (3) |
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292 | (18) |
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292 | (4) |
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296 | (6) |
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13.3 Bone Forming and Bone Formers |
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302 | (2) |
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13.4 Hyperostosis Frontalis Interna |
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304 | (1) |
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305 | (2) |
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307 | (3) |
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310 | (15) |
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310 | (3) |
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14.2 Ante-mortem Tooth Loss |
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313 | (1) |
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314 | (1) |
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315 | (1) |
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316 | (2) |
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14.6 Developmental Defects of Enamel |
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318 | (3) |
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321 | (1) |
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322 | (3) |
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325 | (20) |
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15.1 What Are We Dealing With? |
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325 | (1) |
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15.2 The Frequency of Disease |
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326 | (5) |
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15.3 Comparing Prevalences |
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331 | (5) |
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15.4 Qualitative Comparisons |
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336 | (3) |
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339 | (1) |
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340 | (3) |
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15.7 Case-Control (Case-Referent) Studies |
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343 | (2) |
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345 | (11) |
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16.1 Morphology and Morbidity |
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346 | (1) |
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16.2 Being at the Wrong End |
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347 | (1) |
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16.3 Osteoarthritis and Occupation |
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348 | (3) |
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16.4 Stress Markers and Their Relation to the Mortality of Children |
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351 | (2) |
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16.5 Height and Longevity |
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353 | (1) |
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16.6 Implications for Paleopathology of Wrong-End Epidemiology |
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354 | (2) |
Index |
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356 | |