This new textbook has an international authorship and is a practical, up-to-date resource for clinicians responsible for the care of children with oncologic and malignant hematologic disease. It is specifically designed for practicing oncologists and hematologists, pediatricians with an interest in childhood cancer and trainees seeking a systematic approach to these disorders. This new textbook has an emphasis on the visual presentation and ease of reading of contemporary and comprehensive information for children’s cancers and contains detailed tables, fact boxes and illustrations.
The textbook begins with an introduction to the general principles of the scientific foundation and treatment of childhood cancers and hematological malignancies. Separate sections are then devoted to descriptions of central nervous system tumors, hematological malignancies and solid tumors of childhood which encompass epidemiology, cellular and molecular biology, cancer genetics, immunology, pharmacology and the findings of clinical trials. For each area of science covered, key original references and reviews are highlighted to direct further reading.
Diagnostic, biological, and therapeutic issues are integrated into each tumor-specific chapter, with evidence supporting the current rationales for risk stratification and the development of novel therapies. A final section then explores supportive care, palliative care, late effects considerations and psychosocial issues as relate to children’s cancer.
Recenzijos
It is compact, concise, and easy to read and understand, and certainly a useful addition to the field. (Doody's, 3 August 2012)
"However, overall, this is a useful book, probably most useful for paediatricians who may be providing shared care for paediatric oncology patients, junior doctors on haematology/oncolgy ward." (The Bulletin of the Royal College of Pathologists, 1 July 2011)
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1 | (6) |
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Part I Central Nervous System Tumors of Childhood |
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7 | (68) |
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2 Low-and High-Grade Glioma |
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9 | (15) |
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24 | (10) |
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34 | (18) |
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5 Pediatric Spinal Cord Tumors |
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52 | (10) |
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6 Pediatric Craniopharyngioma, Mixed Glioneuronal Tumors, and Atypical Teratoid/Rhabdoid Tumor |
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62 | (13) |
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Part II Hematological Disorders |
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75 | (88) |
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7 Acute Lymphoblastic Leukemia |
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77 | (18) |
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8 Acute Myeloid Leukemia and Myelodysplastic Disorders |
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95 | (14) |
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109 | (21) |
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130 | (19) |
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149 | (14) |
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Part III Solid Tumors of Childhood |
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163 | (170) |
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165 | (28) |
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193 | (23) |
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216 | (18) |
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306 | (13) |
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319 | (14) |
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Part IV Supportiv Care, Long-Term Issues, and Palliative Care |
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333 | (88) |
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20 Supportive Care: Physical Consequences of Cancer and its Therapies |
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335 | (25) |
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21 Psychosocial Needs of Children with Cancer and Their Families |
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360 | (7) |
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22 Late Effects in Relation to Childhood Cancer |
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367 | (25) |
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392 | (23) |
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24 Clinical Trials Involving Children with Cancer --- Organizational and Ethcical Issues |
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415 | (6) |
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| Index |
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421 | |
Edward J. Estlin, BSc (Hons), PhD, MRCP, FRCPCH Macmillan Consultant in Paediatric Oncology, Department of Paediatric Oncology, Royal Manchester Childrens Hospital, Manchester, UK Richard J. Gilbertson, B.Med.Sci (Hons), MRCP, PhD Co-Leader, Neurobiology and Brain Tumor Program; Director, Molecular Clinical Trials Core, Departments of Developmental Neurobiology and Oncology, St Jude Childrens Research Hospital, Memphis, TN, USA
Robert F. Wynn, BA, MD, MRCP, FRCPath Consultant Paediatric Haematologist and Programme Director, Blood and Marrow Transplant Unit, Royal Manchester Childrens Hospital, Manchester, UK
