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El. knyga: Pediatric Solid Organ Transplantation

Edited by (Birmingham Childrens Hospital), Edited by (SUNY at Stony Brook), Edited by (Harvard Medical School, Boston), Edited by (University of Pennsylvania, Philadelphia, PA, USA), Edited by (Children's Hospital of Pittsburgh, Pittsburgh, PA)
  • Formatas: PDF+DRM
  • Išleidimo metai: 08-Apr-2009
  • Leidėjas: Wiley-Blackwell
  • Kalba: eng
  • ISBN-13: 9781444312737
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  • Formatas: PDF+DRM
  • Išleidimo metai: 08-Apr-2009
  • Leidėjas: Wiley-Blackwell
  • Kalba: eng
  • ISBN-13: 9781444312737
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Fine (pediatrics, Stony Brook U. School of Medicine, New York) et al. present the second edition of this text covering pediatric solid organ transplantation. As with the first edition, the two introductory sections address issues common to all transplants--four new chapters on immunosuppression and its complications address mechanisms of action, therapies for the sensitized patient, and post-transplant lymphoproliferative disorders. The following five sections address organ-specific surgical techniques and pre-op and follow-up care for organ for various transplants. A new concluding section covers post-op quality-of-live issues such as cognitive development, psychosocial adaptation and adherence, puberty, and pregnancy. This reference is intended for pediatric specialists and transplantation sub-specialists as well as transplant surgeons. Annotation ©2007 Book News, Inc., Portland, OR (booknews.com)

Pediatric Solid Organ Transplantation is a comprehensive and succinct text on all aspects of pediatric solid organ transplantation. It provides a ready source of reference, to both the basic science and organ specific surgical technique and after care. This second edition has been extensively updated in light of recent developments in this rapidly advancing area.

The only textbook devoted to the field of pediatric transplantation


  • A definitive reference for all those interested in improving the care and quality of life of children undergoing solid organ transplantation
  • Section on immunosuppression has been expanded by four chapters to include sections on;
    - mechanisms of action
    - therapies for the sensitized patient
    - post-transplant lymphoproliferative disorders
    - organ toxicities of immunosuppressive therapy
  • A new section has been added on the many topics related to quality of life that effect survivors of pediatric transplantation
  • International editorial and contributor team represents a wide geographical range and contains both recognized leaders and emerging experts

Whether you are an established sub-specialist in pediatric transplantation, a transplant surgeon, or a pediatric specialist in a related area, this book will answer all your questions about care of the pediatric patient before, during, and after transplantation.

Recenzijos

"This is a useful and readable reference for the pathologist, but mainly because of the basic scientific and clinical information provided rather than for its coverage of allograft pathology. (Pediatric and Developmental Pathology) This remains the only text devoted to pediatric transplant issues and accomplishes the stated goalsIt serves to fill a void in the field. (Doodys Review Service)

"A comprehensive text written by experienced authors on all aspects of solid organ transplantation." (Paediatric Endocrinology Reviews)

Section 1 Immunology and Genetics.
1 The Immune Response to Organ Allografts.
2 Allorecognition Pathways.
3 Costimulation.
4 The HLA System and Histocompatibility Testing for Organ Transplantation.
5 Gene Polymorphisms and Pharmacogenomics.
6 Genomics and Proteomics as Research Tools.
7 Tolerance: A Review of its Mechanisms in the Transplant Setting.
Section 2 Immunosuppression and its Complications.
8 Mechanisms of Action of Immunosuppressive Agents.
9 Induction and Maintenance Immunosuppression.
10 Novel Immunosuppressants.
11 Therapies for the Allosensitized Patient.
12 Infections Post-Transplantation.
13 Post-Transplant Lymphoproliferative Disorders and Malignancy.
14 Organ Toxicities.
Section 3 Kidney Transplantation.
15 Historical Notes.
16 Recipient Characteristics.
17 Evaluation of the Candidate.
18 Donor Evaluation, Surgical Technique and Perioperative Management.
19 Pathology of the Kidney Allograft.
20 Post-Transplant Management.
21 Outcomes and Risk Factors.
Section 4 Liver Transplantation.
22 Historical Notes.
23 Recipient Characteristics.
24 Evaluation of the Candidate.
25 Donor Evaluation, Surgical Technique and Perioperative Management.
26 Pathology of the Liver Allograft.
27 Post-Transplant Management.
28 Outcomes and Risk Factors.
Section 5 Heart Transplantation.
29 Historical Notes.
30 Recipient Characteristics.
31 Evaluation of the Candidate.
32 Donor Evaluation, Surgical Technique and Perioperative Management.
33 Pathology of the Cardiac Allograft.
34 Post-Transplant Management.
35 Outcomes and Risk Factors.
Section 6 Lung and Heart-Lung Transplantation.
36 Historical Notes.
37 Recipient Characteristics.
38 Evaluation of the Candidate.
39 Donor Evaluation, Surgical Technique and Perioperative Management.
40 Pathology of the Lung Allograft.
41 Post-Transplant Management.
42 Outcomes and Risk Factors.
Section 7 Intestinal Transplantation.
43 Historical Notes.
44 Recipient Characteristics.
45 Evaluation of the Candidate.
46 Donor Evaluation, Surgical Technique and Perioperative Management.
47 Pathology of the Intestinal Allograft.
48 Post-Transplant Management.
49 Outcomes and Risk Factors.
Section 8 Special Issues after Pediatric Transplantation.
50 Growth and Puberty.
51 Cognitive Development.
52 Psychosocial Adaptation and Adherence .
53 Pregnancy.
54 Gynecologic Issues.
55 Transition to Adult Care.
Index
Professor Richard Fine, Professor and Chairman, Department of Paediatrics, State University of New York, USA Dr Steve Webber, Division of Cardiology, Children's Hospital of Pittsburgh, USA



Dr William Harman, Associate Professor of Paediatrics, Harvard Medical School, Boston, USA