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Pharmaceuticals and Personal Care Products: Waste Management and Treatment Technology: Emerging Contaminants and Micro Pollutants [Minkštas viršelis]

Edited by (Emeritus Professor and Former Dean, School of Life Sciences, University of Hyderabad, Hyderabad, Telangana, India), Edited by , Edited by (Professor, University of Sri Jayewardenepura, Sri Lanka)
  • Formatas: Paperback / softback, 506 pages, aukštis x plotis: 229x152 mm, weight: 790 g
  • Išleidimo metai: 05-Apr-2019
  • Leidėjas: Butterworth-Heinemann Inc
  • ISBN-10: 0128161892
  • ISBN-13: 9780128161890
  • Formatas: Paperback / softback, 506 pages, aukštis x plotis: 229x152 mm, weight: 790 g
  • Išleidimo metai: 05-Apr-2019
  • Leidėjas: Butterworth-Heinemann Inc
  • ISBN-10: 0128161892
  • ISBN-13: 9780128161890

Pharmaceuticals and Personal Care Products Waste Management and Treatment Technology: Emerging Contaminants and Micro Pollutants provides the tools and techniques for identifying these contaminates and applying the most effective technology for their remediation, recovery and treatment. The consumption of pharmaceuticals and personal care products (PPCPs) has grown significantly over the last 35 years, thus increasing their potential risk to the environment. As PPCPs are very difficult to detect and remove using conventional wastewater treatment methods, this book provides solutions to a growing problem.

  • Includes sampling, analytical and characterization methods and technology for detecting PPCPs in the environment
  • Provides advanced treatment and disposal technologies for the removal of PPCPs from wastewater, surface water, landfills and septic systems
  • Examines the pathways of PPCPs into the environment
List of contributors
xv
Biographies xix
Foreword xxi
Preface xxxv
Acknowledgments xxxvii
1 Pharmaceuticals and personal care product (PPCP) contamination---a global discharge inventory
1(26)
Saptarshi Dey
Farhat Bano
Anushree Malik
1.1 Introduction
1(3)
1.1.1 Water, pollution, and the world
1(1)
1.1.2 Emerging contaminants in the environment
2(1)
1.1.3 Pharmaceuticals and personal care products
3(1)
1.2 What are pharmaceuticals and personal care products?
4(9)
1.2.1 Pharmaceuticals and personal care products: widest category of emerging contaminants
4(2)
1.2.2 Categorization of pharmaceuticals and personal care products
6(4)
1.2.3 Sources, pathways, and occurrences
10(3)
1.3 Environmental studies and impact of pharmaceuticals and personal care products
13(5)
1.3.1 Environmental risks with pharmaceuticals and personal care products
13(3)
1.3.2 Treatment of pharmaceuticals and personal care products
16(2)
1.4 Global research and prospects
18(1)
1.5 Conclusion
19(8)
References
20(7)
2 Pharmaceutical and personal care product contamination: a global scenario
27(36)
Vipin Chandra Kalia
2.1 Introduction
27(1)
2.2 Distribution of pharmaceutical and personal care products in the environment
28(35)
2.2.1 Europe
28(11)
2.2.2 Asia
39(3)
2.2.3 United States
42(3)
2.2.4 Canada
45(1)
2.2.5 South America
45(1)
2.2.6 Australia and New Zealand
46(1)
2.2.7 Africa
46(1)
2.2.8 Impact of pharmaceutical and personal care products on health of aquatic organisms
47(4)
2.2.9 Opinion
51(1)
Acknowledgments
51(1)
References
51(10)
Further reading
61(2)
3 Pharmaceuticals and personal care products in aquatic environment: chemicals of emerging concern?
63(24)
Rita S. Dhodapkar
Kavita N. Gandhi
3.1 Introduction
63(7)
3.1.1 Definition and classification
63(2)
3.1.2 Sources of pharmaceuticals and personal care products in aquatic environment
65(1)
3.1.3 Environmental pathways, fate, and persistence in aquatic environment
65(2)
3.1.4 Ecotoxicological profile and impact
67(3)
3.2 Control strategies
70(6)
3.2.1 Background
70(1)
3.2.2 Water treatment systems: removal efficiency for pharmaceuticals and personal care products
71(4)
3.2.3 Control measures
75(1)
3.3 Regulatory status: global perspective
76(11)
References
78(7)
Further reading
85(2)
4 Uptake and accumulation of pharmaceuticals and personal care products in leafy vegetables
87(28)
Tharuka Jayampathi
Thilakshani Atugoda
Chamila Jayasinghe
4.1 Introduction
87(1)
4.2 Modes of pharmaceuticals and personal care product contamination of leafy vegetables
88(2)
4.2.1 Application of amended biosolids
88(1)
4.2.2 Use of reclaimed water for irrigation
89(1)
4.3 Common pharmaceuticals and personal care products in leafy vegetables
90(6)
4.3.1 Pharmaceuticals
90(1)
4.3.2 Personal care products
91(5)
4.4 Factors influencing uptake of pharmaceuticals and personal care products
96(2)
4.4.1 Soil organic matter
96(1)
4.4.2 Soil pH
96(1)
4.4.3 Source of pharmaceuticals and personal care products
96(1)
4.4.4 Chemical hydrophobicity
96(1)
4.4.5 Molecular ionization
97(1)
4.4.6 Plant lipid content
97(1)
4.4.7 Transpiration rate
98(1)
4.5 Determining accumulation of PPCPs in different plant tissues
98(3)
4.5.1 Bioconcentration factor/Bioaccumulation factor
98(1)
4.5.2 Translocation factor
99(2)
4.6 Human exposure implications of pharmaceuticals and personal care products in leafy vegetables
101(2)
4.6.1 Average daily consumption
101(1)
4.6.2 Annual exposure
101(1)
4.6.3 Lowest observable effect concentration
102(1)
4.7 Processing effects
103(1)
4.8 Future perspectives
103(12)
References
107(8)
5 Health effects of pharmaceuticals and personal care products
115(14)
Kaiser Jamil
5.1 Introduction
115(1)
5.2 Defining nanomaterials
116(1)
5.3 Classification of pharmaceuticals and personal care products
117(1)
5.4 Methods to detect cytotoxicity of pharmaceuticals and personal care product components
118(5)
5.4.1 3-(4, 5-Dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide assays
118(1)
5.4.2 Cytotoxicity assays
118(1)
5.4.3 Cell viability assays
119(1)
5.4.4 Mitotoxicity assays
119(1)
5.4.5 Lipotoxicity assays
120(1)
5.4.6 Genotoxicity assays
120(1)
5.4.7 Cytotoxicity assays
120(3)
5.5 Modern nanotechnology and biotechnology methods developed in determining toxicity of pharmaceuticals and personal care product components
123(1)
5.6 Alternatively, computational screening approaches
124(1)
5.6.1 In silico methodologies
124(1)
5.7 Future studies
124(5)
Acknowledgments
125(1)
Conflict of interest
125(1)
References
126(3)
6 Treatment methods for removal of pharmaceuticals and personal care products from domestic wastewater
129(22)
Harkirat Kaur
Girivyankatesh Hippargi
Girish R. Pophali
Amit Kumar Bansiwal
6.1 Introduction
129(1)
6.2 Treatment methods
130(10)
6.2.1 Conventional treatment methods
130(3)
6.2.2 Advanced treatment
133(7)
6.3 Conclusion and future prospects
140(11)
References
141(9)
Further reading
150(1)
7 Removal of pharmaceuticals and personal care products by ozonation, advance oxidation processes, and membrane separation
151(22)
Anna Kwarciak-Kozlowska
7.1 Removal of pharmaceuticals and personal care products by ozonation, advanced oxidation, and membrane separation
151(14)
7.1.1 Classification of pharmaceuticals and personal care products
152(2)
7.1.2 Sources and fate of pharmaceuticals and personal care products in the environment
154(4)
7.1.3 Removal of pharmaceutical and personal care products by advanced oxidation processes
158(4)
7.1.4 Removal of pharmaceutical and personal care products by membrane separation
162(3)
7.2 Conclusion
165(8)
References
166(7)
8 Removal of pharmaceutical and personal care products from wastewater using advanced materials
173(40)
Amruta Morone
Prajakatta Mulay
Sanjay P. Kamble
8.1 Introduction
173(1)
8.2 Environmental risk of pharmaceuticals and personal care products
174(1)
8.3 Environmental fate and behavior of pharmaceuticals and personal care products
174(2)
8.4 Challenges presented by pharmaceuticals and personal care products in wastewater treatment
176(1)
8.5 Pharmaceuticals and personal care product removal technologies
176(13)
8.5.1 Primary and secondary treatment
177(3)
8.5.2 Sand filtration
180(1)
8.5.3 Separation technologies
180(1)
8.5.4 Natural or passive treatment technologies
181(1)
8.5.5 Adsorption
182(1)
8.5.6 Advanced oxidation processes
183(5)
8.5.7 Hybrid processes
188(1)
8.6 Advanced materials for pharmaceuticals and personal care product removal
189(14)
8.6.1 Advanced materials for adsorption
189(10)
8.6.2 Advanced materials for advanced oxidation processes
199(4)
8.7 Conclusions
203(10)
References
203(10)
9 Sorptive removal of pharmaceutical and personal care products from water and wastewater
213(26)
Anushka Upamali Rajapaksha
Kadupitige Shashikala Dilrukshi Premarathna
Viraj Gunarathne
Aashiq Ahmed
Meththika Vithanage
9.1 Introduction
213(2)
9.2 Technologies available for pharmaceutical and personal care products removal
215(1)
9.3 Pharmaceutical and personal care products removal using commercial activated carbons
216(1)
9.4 Nonconventional low-cost sorbents for the removal of pharmaceutical and personal care products
217(6)
9.4.1 Agricultural solid waste
217(2)
9.4.2 Industrial by-products
219(1)
9.4.3 Natural clay minerals
220(1)
9.4.4 Biosorbents
221(1)
9.4.5 Synthetic sorbents
222(1)
9.5 Biochar and engineered/design biochar for pharmaceutical and personal care products removal
223(7)
9.5.1 Use of engineered design biochar for the removal of pharmaceutical and personal care product
224(3)
9.5.2 Adsorption mechanisms of pharmaceutical and personal care products by biochar/engineered biochar
227(3)
9.6 Environmental factors influence for sorptive removal
230(1)
9.7 Conclusions and future perspectives
231(8)
References
232(7)
10 Analytical techniques and challenges for removal of pharmaceuticals and personal care products in water
239(20)
Jialing Shen
Tao Ding
Ming Zhang
10.1 Analytical techniques
239(6)
10.1.1 Sample preparation techniques
240(3)
10.1.2 Quantitative analysis
243(2)
10.2 Removal of pharmaceuticals and personal care products from water
245(14)
10.2.1 Removal of pharmaceuticals and personal care products in conventional treatment plant
245(2)
10.2.2 Advanced control strategies to remove pharmaceuticals and personal care products
247(4)
References
251(6)
Further reading
257(2)
11 Microbial degradation of xenobiotics like aromatic pollutants from the terrestrial environments
259(20)
Prashant S. Phale
Amrita Sharma
Kamini Gautam
11.1 Introduction
259(1)
11.2 Microbial degradation of aromatic compounds
260(1)
11.3 Enzymes involved in the biodegradation of aromatic compounds
261(2)
11.3.1 Hydrolases
261(1)
11.3.2 Dehalogenase
261(1)
11.3.3 Oxygenases
261(2)
11.3.4 Dehydrogenases
263(1)
11.3.5 Oxidases
263(1)
11.4 Aromatic pollutants in the environment and their metabolism
263(8)
11.4.1 Phthalate isomers
263(1)
11.4.2 Naphthalene
264(2)
11.4.3 Phenanthrene
266(2)
11.4.4 Benzo(a)pyrene
268(1)
11.4.5 Pesticides
268(3)
11.5 Applications and future directions
271(1)
11.6 Conclusions
272(7)
References
273(6)
12 Nanotechnology applications for the removal of environmental contaminants from pharmaceuticals and personal care products
279(18)
Ryan Rienzie
Sammani Ramanayaka
Nadeesh M. Adassooriya
12.1 Introduction
279(1)
12.2 Nanotechnology-based methods for the removal of environmental contaminants from PPCPs
280(9)
12.2.1 Nanomaterial-based absorptive techniques
280(3)
12.2.2 Photocatalysis
283(1)
12.2.3 Nanofiltration techniques
284(5)
12.3 Concluding remarks and future implications
289(8)
References
289(6)
Further reading
295(2)
13 Plant-based technologies for removal of pharmaceuticals and personal care products
297(24)
Monika Galwa-Widera
13.1 Introduction
297(1)
13.2 Pharmaceuticals and personal care products: what it means
298(4)
13.2.1 Lanolin
300(1)
13.2.2 Paraffin
300(1)
13.2.3 Silicone oils
301(1)
13.2.4 Sodium lauryl sulfate and sodium laureth sulfate
301(1)
13.2.5 Polyethylene glycol
302(1)
13.3 Pharmaceuticals in the aquatic environment
302(4)
13.4 Threats caused by the presence of pharmaceuticals and personal care products in the environment
306(1)
13.5 Removal of pharmaceuticals from water and sewage
307(2)
13.6 Legal regulations regarding pharmaceutical substances in the environment
309(5)
13.6.1 Legal regulations in Europe
309(3)
13.6.2 Legal regulations in the world
312(2)
13.7 Removal of impurities by hydrobotanic methods
314(2)
13.8 Conclusion
316(5)
References
316(3)
Further reading
319(2)
14 Removal of pharmaceuticals and personal care products by aquatic plants
321(20)
Bhupinder Dhir
14.1 Introduction
321(3)
14.2 Uptake and accumulation of pharmaceuticals and personal care products by aquatic plants
324(2)
14.3 Degradation of pharmaceuticals and personal care products in plants
326(2)
14.4 Constructed wetlands
328(2)
14.5 Conclusions
330(11)
References
330(11)
15 The role of microorganisms in the removal of pharmaceutical and personal care products
341(42)
Dong Zhang
15.1 Biological sorption of typical pharmaceutical and personal care products
342(21)
15.1.1 Biological sorption of pharmaceutical and personal care products
342(18)
15.1.2 Factors affecting sorption of pharmaceutical and personal care products
360(3)
15.2 Transmembrane mechanisms of pharmaceutical and personal care products
363(5)
15.2.1 Theoretical transmembrane flux
363(2)
15.2.2 Transmembrane route
365(3)
15.3 Biotransformation of pharmaceutical and personal care products
368(8)
15.3.1 Typical degrading strains, related enzymes and pathways of typical pharmaceutical and personal care products
368(4)
15.3.2 Factors
372(4)
15.4 Conclusion
376(7)
References
376(6)
Further reading
382(1)
16 Development of antimicrobial resistance: future challenges
383(26)
Delfina C. Dominguez
Samantha M. Meza-Rodriguez
16.1 Introduction
383(1)
16.2 History of antibiotics
384(1)
16.3 Development of antibiotic resistance
385(1)
16.4 Mechanisms of resistance
386(2)
16.5 Spread of antimicrobial resistance
388(3)
16.5.1 Conjugation, transformation, and transduction
388(2)
16.5.2 Mobile genetic elements
390(1)
16.6 Superbugs
391(3)
16.7 Antimicrobial resistance in the environment
394(1)
16.8 New therapeutic approaches
395(1)
16.9 Phage lysins
396(3)
16.10 Signaling inhibitors
399(1)
16.11 Antimicrobial peptides
399(1)
16.12 Antibodies to treat infections
400(1)
16.13 Conclusions
400(9)
Glossary
401(1)
References
402(7)
17 Pharmaceuticals and personal care products mediated antimicrobial resistance: future challenges
409(20)
Shailendra Yadav
Niti B. Jadeja
Nishant A. Dafale
Hemant J. Purohit
Atya Kapley
17.1 Introduction
409(2)
17.1.1 What are pharmaceuticals and personal care products?
410(1)
17.2 Types and source of pharmaceuticals and personal care products
411(8)
17.2.1 Cross-reactivity of pharmaceuticals and personal care products mediating antimicrobial resistance
414(1)
17.2.2 Status of antibiotic resistance in India
415(2)
17.2.3 Dissemination of antimicrobial resistance in diverse niche through biological route
417(2)
17.3 Future challenges
419(10)
17.3.1 Implementation of policy/laws for the judicious use of antibiotics
419(1)
17.3.2 Development of vaccine against deadly disease
419(2)
17.3.3 Application of microbial intelligence for combating antibiotic resistance
421(1)
17.3.4 Discovery of new antimicrobials compounds as therapeutics
421(2)
Acknowledgment
423(1)
References
424(5)
18 Antibiotics induced antibacterial resistance
Pathmalal M. Manage
Gayani Yasodara Liyanage
18.1 Introduction
429(20)
18.2 Sources and contamination status of antibiotics
430(1)
18.2.1 Human therapy
430(1)
18.3 Antibiotics in agriculture (aquaculture, animal farms, veterinary clinics)
431(2)
18.4 Metabolism of antibiotic compounds
433(1)
18.5 Major pathways of environmental contamination of antibiotics
434(3)
18.6 Development of antibiotic resistance
437(1)
18.7 Mechanisms of antibiotic resistance
438(1)
18.8 The changes that occur in the receptor that are connected to the drug
438(1)
18.9 Enzymatic inactivation of antibiotics
439(1)
18.10 Reduction of the inner and outer membrane permeability
439(1)
18.11 Flush out of the drug (active pump system)
439(1)
18.12 Using an alternative metabolic pathway
439(1)
18.13 Transfer of resistance genes
439(1)
18.14 Multidrug resistance in bacteria
440(1)
18.15 Risk of antibiotic resistance for human and animal health
440(1)
18.16 Bioremediation of antibiotic as a green solution
441(1)
18.17 Future challenges in aquaculture, livestock, and human health due to antibacterial resistance
442(7)
References
444(5)
Index 449
Dr Meththika Vithanage is a Professor in Natural Resources at University of Sri Jayewardenepura, Sri Lanka. Her research approach builds on enabling measurements of concentrations and reaction rates in environmental samples for key/emerging pollutants in the environment in order to assess their fate and transport to discover solutions to remediate those using different geo/bio/nano materials.

Dr Vithanages contribution to science has been recognized by The World Academy of Sciences (TWAS) presenting the Fayzah M. Al-Kharafi award in 2020. She is a Fellow of the National Academy of Sciences, Sri Lanka, and Institute of Chemistry, Ceylon, and was selected as one of the Early Career Women Scientists by the Organization for Women Scientists in Developing Countries, Italy. Her outstanding performance in research publications was recognized by the Presidential Awards, Sri Lanka, for consecutive 8 years from 2011 Dr. Prasad is Emeritus Professor, School of Life Sciences, University of Hyderabad (India). He has made outstanding contributions to the fields of bioremediation, bioresources, biomass energy sources, bioeconomy, and to the broad field of environmental biotechnology, all of which are his main areas of expertise. Dr. Prasad has served the Government of Indias Ministry of Environment, Forests and Climate Change as a member of various advisory committees on biodiversity conservation, ecosystem services, pollution control and abatement, environmental information systems and bioremediation of contaminated sites. He is an active visiting scientist for several international universities.