The WHO estimates that physical activity and weight control could prevent a quarter of common cancers. This book shows how obesity and sedentary lifestyles adversely affect cancer risk and survival for individuals, and analyzes the causal mechanisms.
The World Health Organization estimates that 25 percent of common cancers can be prevented through regular physical activity and weight control. Common cancers linked to overweight/obesity and a sedentary lifestyle include breast, colon, endometrium, pancreas, renal, esophageal, and several others. There are several plausible mechanisms linking lack of physical activity and increased adiposity to cancer risk, supported by results from animal experiments and human intervention studies.
Introduction
Anne McTiernan, Linda Nebeling, Rachel Ballard-Barbash
Epidemiology of overweight/obesity and cancer risk
Eugenia Calle
Epidemiology of physical activity and cancer risk.
Kathryn Schmitz, I-Min Lee, Anne McTiernan
Dietary energy restriction, exercise, and mammary carcinogenesis
Henry Thompson
Animal model of obesity and advanced prostate cancer
Tim Nagy
Dietary energy restriction, exercise, and colon carcinogenesis
Steve Hursting
Mechanisms linking obesity to cancer risk in humans
Catherine Duggan and Anne McTiernan
Mechanisms linking physical activity to cancer risk in humans.
Andrew Rundle
Physical activity, weight control, and cancer prognosis
Kathryn Schmitz and Melinda Irwin
Summary, future directions
Anne McTiernan, Linda Nebeling, Rachel Ballard-Barbash
