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El. knyga: Physics of Thermal Therapy: Fundamentals and Clinical Applications

Edited by (Moffitt Cancer Center, Tampa, Florida, USA)
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"Focusing on applications in cancer treatment, this book covers basic principles, practical aspects, and clinical applications of thermal therapy. An overview of the fundamentals shows how use of controlled heat in medicine and biology involves electromagnetics, acoustics, thermodynamics, heat transfer, and imaging sciences. The book discusses challenges in the use of thermal energy on living tissues and explores genetic, cellular, and physiological responses that will help in combating cancer. It also highlights recent advances, including the treatment of solid tumors using image-guided thermal therapy, microbubbles, nanoparticles, and other cutting-edge techniques. Covers the basic physics of thermal therapy and practical aspects of advanced pre-clinical and clinical systems. Gives an overview of heat transfer, thermal dose models, practical invasive and non-invasive thermometry, and numerical modeling for simulation and treatment planning. Presents the state of the art in clinical thermal therapy systems. Discusses the latest advances in thermoacoustic imaging, non-invasive thermometry, MRI-guided high-intensity focused ultrasound, and enhanced drug delivery using liposomes and hyperthermia. Includes chapters on cutting-edge topics such as magnetic nanoparticles for cancer therapy and thermal therapy applications of microbubbles"--Provided by publisher.

The field of thermal therapy has been growing tenaciously in the last few decades. The application of heat to living tissues, from mild hyperthermia to high-temperature thermal ablation, has produced a host of well-documented genetic, cellular, and physiological responses that are being researched intensely for medical applications, particularly for treatment of solid cancerous tumors using image guidance. The controlled application of thermal energy to living tissues has proven a great challenge, requiring expertise from multiple disciplines, thereby leading to the development of many sophisticated pre-clinical and clinical devices and treatment techniques. Physics of Thermal Therapy: Fundamentals and Clinical Applications captures the breadth and depth of this highly multidisciplinary field.

Focusing on applications in cancer treatment, this book covers basic principles, practical aspects, and clinical applications of thermal therapy. An overview of the fundamentals shows how use of controlled heat in medicine and biology involves electromagnetics, acoustics, thermodynamics, heat transfer, and imaging sciences. The book discusses challenges in the use of thermal energy on living tissues and explores the genetic, cellular, and physiological responses that can be employed in the fight against cancer from the physics and engineering perspectives. It also highlights recent advances, including the treatment of solid tumors using image-guided thermal therapy, microbubbles, nanoparticles, and other cutting-edge techniques.

Recenzijos

"This long overdue volume offers a richly enhanced update on these classic texts, and adds numerous chapters on new areas of research and clinical activity. It is a well-rounded, balanced presentation of the current status of the field of thermal medicine, and is packed with useful new material." Medical Physics, June 2013

Series Preface ix
Preface xi
Editor xiii
Contributors xv
PART I Foundations of Thermal Therapy Physics
1 Fundamentals of Bioheat Transfer
3(20)
Kenneth R. Diller
2 Thermal Dose Models: Irreversible Alterations in Tissues
23(18)
John A. Pearce
3 Practical Clinical Thermometry
41(16)
R. Jason Stafford
Brian A. Taylor
4 Physics of Electromagnetic Energy Sources
57(18)
Jeffrey W. Hand
5 The Physics of Ultrasound Energy Sources
75(20)
Victoria Bull
Gail R. ter Haar
6 Numerical Modeling for Simulation and Treatment Planning of Thermal Therapy: Ultrasound
95(24)
Robert J. McGough
7 Numerical Modeling for Simulation and Treatment Planning of Thermal Therapy
119(20)
Esra Neufeld
Maarten M. Paulides
Gerard C. van Rhoon
Niels Kuster
PART II Clinical Thermal Therapy Systems
8 External Electromagnetic Methods and Devices
139(20)
Gerard C. van Rhoon
9 Interstitial Electromagnetic Devices for Thermal Ablation
159(18)
Dieter Haemmerich
Chris Brace
10 Clinical External Ultrasonic Treatment Devices
177(12)
Lili Chen
Faqi Li
Feng Wu
Eduardo G. Moros
11 Endocavity and Catheter-Based Ultrasound Devices
189(14)
Chris J. Diederich
PART III Physical Aspects of Emerging Technology for Thermal Therapy
12 Evolving Tools for Navigated Image-Guided Thermal Cancer Therapy
203(16)
Kevin Cleary
Emmanuel Wilson
Filip Banovac
13 Temperature Imaging Using Ultrasound
219(22)
R. Martin Arthur
14 Focused Ultrasound Applications for Brain Cancer
241(14)
Meaghan A. O'Reilly
Kullervo Hynynen
15 Extracorporeal Ultrasound-Guided High-Intensity Focused Ultrasound Ablation for Cancer Patients
255(24)
Feng Wu
16 Using Hyperthermia to Augment Drug Delivery
279(14)
Mark W. Dewhirst
17 Magnetic Nanoparticles for Cancer Therapy
293(26)
Michael L. Etheridge
John C. Bischof
Andreas Jordan
18 Application of Gold Nanoparticles (GNP) in Laser Thermal Therapy
319(20)
Zhenpeng Qin
John C. Bischof
19 Thermochemical Ablation
339(14)
Erik N. K. Cressman
Index 353
Eduardo Moros