This book discusses all possible aspects of infectious perinatal pathology caused by different bacterial, viral, fungal, mycoplasma and protozoan pathogens. Brief and concise microbiological, epidemiological and clinical data, and all macro- and histopathological changes are illustrated. Issues related to perinatal pathology are compared with those in children and adults.
Special attention is paid to viral, mycoplasma and chlamydia infections. Chlamydia and Mycoplasma lesions are practically unknown to pathologists dealing with human specimens. Several typical and rare examples from the authors practice are presented as well. The book is important for pathologists and clinicians (obstetricians, neonatologists, paediatricians).
Chapter 1: Morphogenesis of the human placenta.
Chapter 2: The concept of placental insufficiency.
Chapter 3: General principles and methods of morphological diagnostics of perinatal infectious pathology.
Chapter 4: Placental microbiome and intraamniotic infection.
Chapter 5: Transplacental transmission infections : General consideration. Bacterial infections.
Chapter 6: Transplacental transmission infections : Viral infections.
Chapter 7: Transplacental transmission infections : Infections due to Mycoplasma and Protozoa.
Chapter 8: Role of biological pathogens in malformations.
Chapter 9: Clinical manifestations of intrauterine infections.
Vsevolod A. Zinserling (Tsinzerling) was born 1954 in Leningrad (Russia) in the family of Prof. Dr. Alexander Zinserling (1923-1995) - outstanding pathologist. He graduated from Leningrad Paediatric Medical Institute in 1977, worked as research scientist, practicing as pathologist in Leningrad Research Institute of Childrens Infections (1977-1988). In 1978-80 had postgraduate training at the chair of pathology (chief. Prof. O.K. Khmelnitsky) of Leningrad Institute for Postgraduate Medical Training. 1981 defended his cand. med. sc. (Dr. med.) thesis Brain changes in mycoplasmosis. In 1988-92 chief of the Central Research Laboratory of Leningrad Paediatric Medical Institute. In 1988 defended the doct. med. sci. thesis Brain lesions due to respiratory viruses. Since 1992-2007 chief of the Institute of Pathology St. Petersburg Paediatric Medical Academy. Since 2017 V. Zinserling is organizing and providing the postgraduate medical training in pediatric pathology in Russia.He is also providing consultations in the citys Consulting Centre for the Infectious Pathology and. Since 2017 professor of pathology at the V.A. Almazov National Research Center. Author of more than 400 scientific publications devoted to different topics of infectious, perinatal and brain pathology, including manuals (in Russian) Modern Infections (2002), Perinatal infections (2002), Infections of the Nervous System (2005). Author of two books Infectious Lesions of Respiratory tract (2021) and Infectious Lesions of the central Nervous System (2022), by Springer. Participant of many international congresses, being invited lecturer at European Congresses of ESP (2010-2022).
Andrey V. Kolobov graduated from Pediatric Pediatric Medical Academy in 1994, since 1997 after postgraduate training in pathology at the same academy works as pathologist in the field of perinatology and since 2007 is associated professor at medical faculty of Saint-Petersburg University. His cand. med. Sc. Thesis (Dr.med) defended in 2002 was devoted to the pathology of perinatal syphilis. He is author of about 100 publications devoted to perinatal infectious pathology, participant of several European Congresses of ESP.
Sebastian Lucas graduated from UCH London and Oxford in 1973. He became interested in infectious disease pathology and worked in many countries in Africa as well as London. He was professor of pathology at Guy's, King's and St Thomas' Medical School from 1995, retiring in 2022. Particular specialist interests include HIV/AIDS, leprosy, tuberculosis and autopsy pathology.
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