Exploring Biotech. and its application in the improvement of quality of medicinal plants such as basic aspects of biotechnology to implementation using processes like genetic eng. in medicinal plants for higher yield of Phytopharmaceuticals/biotechnological techniques for assessing and improving the quality of products/medicinal plants.
Present book aims to explore the knowledge of Biotechnology and its application in the improvement of quality of medicinal plants. After reading the book students shall be able to know the basic aspects of biotechnology to implementation using processes like genetic engineering in medicinal plants for higher yield of Phytopharmaceuticals and biotechnological techniques for assessing and improving the quality of natural products/medicinal plants. Contributions come from leading scientists from across the globe. Readerships include Natural product chemists, biotechnologist, pharmacognosists, pharmacologists as well as academic and industry researchers. This book is written keeping in mind the requirements of botanists, pharmaceutical chemists, pharmaceutical industry, biotechnologists, microbiologists, and specialists working on plant biotechnology. This book offers an essential guide and a systematic reference for the development of medicinal product with the help of biotechnology from natural products. This is the single book that acts as textbook as well as reference books for students/teachers/scientists working in medicinal plant biotechnology. Moreover, in context of wide piece search for, although reference books are available but none of them seem to contribute sustenance to the need of material on Medicinal Plant Biotechnology. This book features contributions from world-renowned experts in the field of biotechnology, pharmaceutical biology, pharmacognosy, chemistry and pharmaceutical biotechnology.
Features:
Based on comprehensive investigation, though different books are existing on medicinal plant biotechnology yet there is no book available which explicitly explains the role of plant biotechnology from basics to implementation.
This book will give a bare essential evidence and information for all specialists overseeing supportive biotechnology and their utility.
This book will be an indispensable fountain of information for doctors, biotechnologist, pharmaceutics, academicians, masters and undergraduates working on medicinal plant biotechnology for their better utility.
Although books are available on Plant Biotechnology but none of them relates to the subject from basic to application aspects. Further, it discusses about the fundamental techniques in biotechnology and relates them to the implementation to medicinal plant.
This book has been designed keeping in mind the needs of graduate students to researchers, academicians and future entrepreneurs.
Chapter 1: Historical perspectives, prospects for development of plant
biotechnology as a source of medicinal agents. Applications in pharmacy and
allied fields
Chapter 2: Laboratory Requirements to Setup Plant Biotechnology laboratory,
and General laboratory
Chapter 3: Recombinant DNA technology and its application in plant
biotechnology
Chapter 4: Protoplast isolation and fusion
Chapter 5: In vitro propagation of Medicinal and Aromatic plants: The
Current status on Concepts and Methods
Chapter 6: Sterilization methods and techniques involved in tissue culture
with protocols to sterilize different plant parts
Chapter 7: Gene transfer in plants and their application
Chapter 8: Immobilization Techniques of Plant Cells and its Application on
Secondary Metabolite Production
Chapter 9: Cloning of Plant cell: Different methods of cloning and its
applications. Advantages and Disadvantages of plant cell cloning
Chapter 10: Secondary metabolism in tissue cultures with emphasis on
production of medicinal agents. Precursors and elicitors on production of
secondary metabolites. Applications and associated problems.
Chapter 11: Biotransformation: Bioreactors for pilot and large-scale cultures
of plant cells and retention of biosynthetic potential in cell cultures
Chapter 12: Biotransformation: Bioreactor Strategies for Scaling Plant Cell
Cultures and Metabolic Stability
Chapter 13: Methods used in gene identification, localization, and sequencing
of the genes. Applications of PCR in plant genome analysis
Chapter 14: Fermentation Technology for Production of Ergot Alkaloids; Single
Cell Proteins and Enzymes of Pharmaceutical Interest
Chapter 15: Computational Techniques for Drug Discovery from Medicinal
Plants
Chapter 16: Biotechnological Approaches for the Microbial Production of
Plantbased Compounds
Chapter 17: DNA-based approaches for discrimination of medicinal plants from
their adulterants
Chapter 18: Medicinal plants and their chemical compounds in ruminant
nutrition and antimethanogenic effects: The biotechnological approach
Chapter 19: Isolation Techniques of Phytocompounds of the Medicinal Plants
Chapter
20. Potential Role Of Metabolomics In Medicinal Plant Biotechnology
Research
Prof. Deependra Singh (M.Pharm, Ph.D, Post-doc (USA)) is presently working at University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur (C.G.) India. He is chairman of the education regulation committee and central council member of the pharmacy council of India (PCI). He has around 20 years of teaching and research experience. He has 145 research and review papers published in national and international journals. He has written 30 book chapters and two books with Elsevier. He has successfully completed projects funded by ICMR, UGC, AICTE, DST, CGCOST, and several industrial projects. He has citations more than 7943 (h-index of 36 and i10 index of 123-Google scholar) and scopus h-index 30; 3514 citations. He has 2 international, 3 Indian patents and 2 filed. He has been among the top 2% of scientists across the world in the field of pharmacy and pharmacology in a survey by Stanford University, USA for four consecutive years (2021, 2022, 2023, 2024). He was a visiting scientist at the National Center for Natural Products Research, School of Pharmacy, University of Mississippi, USA. He was a recipient of the DHR-ICMR award for young biomedical scientist in 2019, UGC RAMAN international fellow in 2014, UGC research award in 2012, and a number of awards at national and state level for excellence in research. He is a life member of various professional bodies such as the Indian Pharmaceutical Association (IPA), Association of Pharmacy Teachers of India (APTI), Indian Society of Pharmacognosy (ISP), and serving as Vice-President, Central zone APTI 20222027 (Elected), Vice-President, Central zone IPGA 20222025 (Elected), Secretary, Chhattisgarh state branch IPA.
Durgesh Nandini Chauhan, M.Pharm., has several years of academic (teaching) experience at institutes in India in pharmaceutical sciences working in Columbia College of Pharmacy, Raipur CG India. She has taught subjects such as pharmaceutics, pharmacognosy, traditional concepts of medicinal plants, drug delivery, phytochemistry, cosmetic technology, pharmaceutical engineering, pharmaceutical packaging, quality assurance, dosage form designing, and anatomy and physiology. She is a member of the Association of Pharmaceutical Teachers of India, SILAE: Societą Italo-Latinoamericana di Etnomedicina (The Scientific Network on Ethnomedicine, Italy), and others. She has attended several workshops, conferences, and symposiums, including the AICTE-Sponsored Staff Development Program on Effects of Teaching and Learning Skills in Pharmacy: Tool for Improvement of Young Pharmacy Teachers. She has written more than 10 articles published in national and international journals, 15 book chapters, and edited 10 books. She is also active as a reviewer for several international scientific journals and is an active participant at national and international conferences, including Bhartiya Vigyan Sammelan and the International Convention of Society of Pharmacognosy. Presently she has joined Ishita Research Organization, Raipur, India as a freelance writer and guide for students in pharmacy, Ayurvedic, and science in their research projects. She is interested in data analysis, proposal writing, questionnaire design, designing and developing research questionnaires and policy. She is actively engaged with accurately monitoring, investigating, and analyzing all statistical information, professionally presenting information and reports, and investigating and documenting key data and information at the request of senior researchers.
Dr. Nagendra Singh Chauhan obtained his M.Pharm, Ph.D. from the Department of Pharmaceutical Sciences, Dr. H.S. Gour University, Sagar, MP, India. He has around 20 years of research experience. He is presently working as a Senior Scientific Officer Grade-I and Government Analyst at Drugs Testing Laboratory Avam Anusandhan Kendra, Raipur, Chhattisgarh, India. He has professional expertise in Natural Product Isolation and phytopharmacology. He has written more than 70 articles published in national and international journals, and 32 book chapters, and edited 7 books. He is the recipient of the Dr. P. D. Sethi Memorial National Award for the best HPTLC publication from India in the years 2021 and 2022. He is a member of various professional and academic bodies such as the Society of Pharmacognosy India, the International Natural Product Sciences Taskforce (INPST), SILAE: Societą Italo-Latinoamericana di Etnomedicina (The Scientific Network on Ethnomedicine, Italy), Institutional Human Ethical Committee, Association of Pharmaceutical Teachers of India (APTI), and Indian Pharmacy Graduates Association.
Prof. Manju Singh (M.Pharm, Ph.D) is presently working at University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur (C.G.) India. She has around 20 years of teaching and research experience. She is among the top 2% of scientists across the world in the field of Pharmacy and Pharmacology surveyed by Stanford University, USA. She is engaged in research projects focused on studying the role of plant bioactives in devising new treatments mainly for autoimmune disorders and inflammatory diseases in collaboration with various universities in India and abroad. She has around 140 research and review papers published in national and international journals. She has written 30 book chapters and two books with Elsevier. She has citations more than 6867 with h-index 37, i10 index of 94 (Google scholar) and scopus h-index 30; 3525 citations. She has 2 international, 3 Indian patents and 2 filed. She has successfully completed several projects funded by the Indian Council of Medical Research (ICMR), University Grants Commission (UGC), C.G. State Council of Science and Technology (CGCOST), and the Department of Science and Technology (DST). She was a visiting scientist at the Department of Pharmaceutics, University of Mississippi, USA in 2015. She is the recipient of the DHR-ICMR international young Indian biochemist award 201415 and the APTI Prof. C.J. Shishoo Award for Research in Pharm Sciences 2024. She is a life member of professional bodies such as the Indian Pharmaceutical Association (IPA), Association of Pharmacy Teachers of India (APTI), Indian Pharmacy Graduates Association (IPGA), and serving as President, IPGA state branch Chhattisgarh 20222025 (Elected).
