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El. knyga: Plasmonic Nanobubbles: From Physics to Clinics

  • Formatas: 1180 pages
  • Išleidimo metai: 21-Feb-2025
  • Leidėjas: Jenny Stanford Publishing
  • Kalba: eng
  • ISBN-13: 9781040296240
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Plasmonic Nanobubbles: From Physics to ClinicsDidesnis paveikslėlis
  • Formatas: 1180 pages
  • Išleidimo metai: 21-Feb-2025
  • Leidėjas: Jenny Stanford Publishing
  • Kalba: eng
  • ISBN-13: 9781040296240
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This book delves into the transformative potential of external energy in diagnosing and treating diseases, ranging from cancers to malaria, at their core. The strategy is to replace often harmful substances in patients with on-demand diagnostic and therapeutic events in cells. By merging physics, nanotechnology, and biology, laser pulses are converted into tiny explosions, named plasmonic nanobubbles, within cells. By harnessing disease to create energy-converting structures, plasmonic nanobubbles deliver precise diagnostic and therapeutic effects that improve traditional medicine. Their real-time nature supports robotics and artificial intelligence to create cell-level medicine of the future. For instance, plasmonic nanobubbles instantly detect and destroy aggressive cancer cells or malaria parasites that are otherwise undetectable. This book is the first comprehensive resource for understanding plasmonic nanobubble concepts, experiments, and clinical designs in non-invasive diagnostics, biopsy, endoscopy, microsurgery, drug and gene delivery, and therapy.



This book focuses on an interdisciplinary approach using physics, nanotechnology, lasers, and biology to develop cell-level on-demand non-invasive and minimally invasive diagnostics and treatment. The laser pulse–nanoparticle–tissue interaction results in transient vapor nanobubble, on-demand explosions at the nanoscale.

Recenzijos

We are still at an early stage in understanding the potential biomedical applications of the relatively new science of nanotechnology. For years, Dimitri Lapotko has been a pioneer in the exciting field of plasmonic nanobubbles and how this new technology might alter the ways we diagnose and treat human illnesses. In his new book, appropriately titled, Plasmonic Nanobubbles: From Physics to Clinics, he details how this approach has exciting applications for a diverse set of conditions ranging from malaria to cancer. He gives us a unique vision on how the study of physics could one day revolutionize modern medicine.

Dr Peter Hotez

Texas Childrens Hospital, USA; Baylor College of Medicine, USA; Rice University, USA

The goal of treating any disease, especially cancer, is to detect and destroy abnormal cells while leaving normal cells undisturbed. In this book, Dmitri Lapotko presents a multidisciplinary combination of physics and physiology expertise in using plasmonic nanoparticles that can adsorb picosecond laser pulses to deliver drugs, detect pathogens, or destroy specific cells by generating exploding nanobubbles with sub-micron precision. This is an essential text for any clinician or researcher interested in pushing the boundaries of localized and specific therapies.

Dr Joseph A. Zasadzinski

University of Minnesota, USA

In his book, Dmitri Lapotko shows a novel strategy to convert laser energy into diagnostic, surgical, and therapeutic events in patients with cell-level precision. The book describes the universal physical-biological mechanism of laser pulse-generated events, plasmonic nanobubbles. This book, rich with practical experimental and engineering solutions and examples, will help the next generations of researchers and engineers to further advance laser technologies into clinics.

Dr Hans A. Schuessler

Texas A&M University, USA

Introduction

1. Physical Principles and Properties of Plasmonic Nanobubbles

2. Biomedical Mechanisms of Plasmonic Nanobubbles

3. Photothermal Vapor Nano- and Microbubbles around Endogenous Chromophores and Optically Absorbing Dyes

4. Clinical Applications of Laser Pulse-Activated Vapor Nanobubbles: Methods and Technologies

Dmitri Lapotko obtained his PhD in laser physics from Belarus State University and Doctor of Science in bioengineering from A. V. Lykov Heat and Mass Transfer Institute, Belarus. His research in physics, biophotonics, and nanotechnology resulted in the invention of the non-stationary photothermal platform which converts the external energy into precise nano-events such as plasmonic nanobubbles, with multiple medical applications.
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