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Preparation of Phytopharmaceuticals for the Management of Disorders: The Development of Nutraceuticals and Traditional Medicine [Minkštas viršelis]

Edited by (Africa Centre of Excellence in Public Health and Toxicological Research, University of Port Harcourt, Nigeria), Edited by , Edited by (Assistant Professor, Adarsh Vijendra Institute of Pharmaceutical Sciences, School of Pharmacy, Shobhit University, Gangoh-)
  • Formatas: Paperback / softback, 574 pages, aukštis x plotis: 235x191 mm, weight: 1180 g, 115 illustrations (15 in full color); Illustrations, unspecified
  • Išleidimo metai: 06-Nov-2020
  • Leidėjas: Academic Press Inc
  • ISBN-10: 012820284X
  • ISBN-13: 9780128202845
Kitos knygos pagal šią temą:
  • Formatas: Paperback / softback, 574 pages, aukštis x plotis: 235x191 mm, weight: 1180 g, 115 illustrations (15 in full color); Illustrations, unspecified
  • Išleidimo metai: 06-Nov-2020
  • Leidėjas: Academic Press Inc
  • ISBN-10: 012820284X
  • ISBN-13: 9780128202845
Kitos knygos pagal šią temą:

Preparation of Phytopharmaceuticals for the Management of Disorders: The Development of Nutraceuticals and Traditional Medicine presents comprehensive coverage and recent advances surrounding phytopharmaceuticals, nutraceuticals and traditional and alternative systems of medicines. Sections cover the concepts of phytopharmaceuticals, their history, and current highlights in phytomedicine. Also included are classifications of crude drugs, herbal remedies and toxicity, traditional and alternative systems of medicine, nanotechnology applications, and herbal cosmeticology. Final sections cover applications of microbiology and biotechnology in drug discovery.

This book provides key information for everyone interested in drug discovery, including medicinal chemists, nutritionists, biochemists, toxicologists, drug developers and health care professionals. Students, professors and researchers working in the area of pharmaceutical sciences and beyond will also find the book useful.

  • Includes the history and current highlights in phytomedicine, along with classifications of crude drugs, herbal drug technologies and herbal cosmeticology
  • Provides detailed information on herbal remedies and toxicity, traditional and alternative systems of medicine, and applications of microbiology and biotechnology in drug discovery
  • Discusses the nutritional and health benefits of nutraceuticals and how they help in the management and treatment of metabolic diseases

Recenzijos

"I have reviewed many books on the topic of phytomedicine and what sets this text apart from others is its completeness, from the basic science of phytomedicine development, its uses in therapy, and the cultural aspects of what is deemed by many as traditional medicine. This is the first edition and will need periodic updating." --Doody

Contributors xi
I Phytopharmaceuticals and technology
1 General principle of primary and secondary plant metabolites: Biogenesis, metabolism, and extraction
Charles Oluwaseun Aderunji
Santwana Palai
Chika Precious Ekwuabu
Chukwuebuka Egbuna
Juliana Bunmi Aderunji
Chioma Bertha Ehis-Eriakha
Shyam Sundar Kesh
Andrew G. Mtewa
1.1 Introduction
4(1)
1.2 Plant metabolites
4(3)
1.3 Biogenesis of primary and secondary plant metabolites
7(3)
1.4 Medicinal potentials of plant secondary metabolites
10(4)
1.5 Processing, extraction, and isolation of plant metabolites
14(3)
1.6 Quality and safety
17(1)
1.7 Conclusion
17(8)
References
17(8)
2 Phytopharmaceuticals: Efficacy, safety, and regulation
Andrew G. Mtewa
Chukwuebuka Egbuna
Tamirat Bekele Beressa
Kennedy J. Ngwira
Fanuel Lampiao
2.1 Introduction
25(1)
2.2 Efficacy and safety aspects of phytopharmaceuticals
26(2)
2.3 Phytopharmaceutical mechanisms of action at a molecular level
28(6)
2.4 Safety profile of phytopharmaceuticals
34(1)
2.5 Industrialization of phytopharmaceuticals
35(1)
2.6 Regulation of phytopharmaceuticals products
35(1)
2.7 Conclusion and future prospects
36(3)
References
36(3)
3 Phytomedicine: Scope and current highlights
Manisha Nigam
3.1 Introduction
39(1)
3.2 Historical perspective
40(2)
3.3 Science technologies and phytomedicine: Present scenario
42(1)
3.4 Confronts in phytomedicine
43(3)
3.5 Plants and phytomedicine: Coupling plant physiology and biochemistry to human healthiness
46(5)
3.6 Phytomedicine: From secondary metabolites to biological activities
51(1)
3.7 Conclusion
51(4)
Glossary
52(1)
References
52(3)
4 Ancient and modern practices in phytomedicine
Jaya Vikas Kurhekar
4.1 Introduction
55(1)
4.2 History
55(6)
4.3 Practice in various parts of the world
61(1)
4.4 Present scenario
62(2)
4.5 Application of phytomedicine in real life
64(5)
4.6 Novel bioactive compounds of medicinal importance
69(1)
4.7 Modern methods in phytomedicine
69(1)
4.8 Ethics in phytomedicine
70(1)
4.9 Conclusion and future scenario
71(7)
References
71(7)
5 Herbal drug technology
Mohammad Ali Shariati
Muhammad Usman Khan
Godswill Ntsomboh-Ntsefong
Muhammad Bilal Hussain
Muhammad Akram
Abhay Prakash Mishra
Chukwuebuka Egbuna
5.1 Introduction
78(1)
5.2 Concerns in the use of herbal medicines
79(1)
5.3 Shortcomings and safety issues
80(1)
5.4 Analytical profile of some herbal medicines
80(2)
5.5 Standardization of herbal drugs
82(1)
5.6 Chromatographic fingerprint analysis: Techniques and classification
83(1)
5.7 Conclusion
83(6)
References
84(5)
6 Herbal remedies, toxicity, and regulations
Temitope A. Oyedepo
Santwana Palai
6.1 Introduction
89(1)
6.2 Importance of herbal therapies
90(4)
6.3 Herbs versus conventional drugs
94(1)
6.4 Efficacy and safety of herbal medicine
95(5)
6.5 Validation of herbal therapies
100(2)
6.6 Toxicity and interactions of herbal preparations
102(8)
6.7 Adverse reactions of selected herbal remedies
110(3)
6.8 General concept of evaluation and quality control assessment by drug regulations
113(2)
6.9 Herbal drug regulation in India
115(1)
6.10 Summary and conclusion
116(13)
References
117(12)
7 Herbal cosmeticology
Shahira M. Ezzat
Mahitab H. El Bishbishy
Dina M. El Kersh
Ahmed Zayed
Mohamed A. Salem
Maha M. Salama
7.1 Introduction
129(2)
7.2 Herbal cosmetics
131(4)
7.3 Advantages of herbal over conventional cosmetics
135(1)
7.4 Applications of herbal products in cosmetics
136(3)
7.5 Ayurvedic concepts in herbal cosmeticology
139(1)
7.6 Skin aging
139(3)
7.7 Preparations of herbal cosmetics
142(3)
7.8 Plants/botanicals for skin care
145(4)
7.9 Plant metabolites and uses
149(7)
7.10 Hair care
156(3)
7.11 Conclusion
159(10)
References
159(10)
8 Herbal wound healing agents
Saurav Yadav
Abhay Prakash Mishra
Shambhu Kumar
Abha Negi
Asha
Vineet Kumar Maurya
8.1 Introduction
169(1)
8.2 Wound healing agents of nonplant origins
170(1)
8.3 Wound healing agents of plant (herbal) origins
171(8)
8.4 Summary
179(1)
8.5 Conclusion
179(6)
Glossary
180(1)
References
181(4)
9 Principles of applied microbiology and biotechnology: Technique for the screening of antimicrobial herbs
Alloysius Chibuike Ogodo
M.S. Sandeep Veda Narayana
P. Seshu Vardhan
Rakesh Kumar Gupta
Ajay Kumar Gautam
Chukwuebuka Egbuna
Prem Prakash Kushwaha
Atul Kumar Singh
Shashank Kumar
9.1 Introduction
185(1)
9.2 General techniques of microbiology: Preparation and sterilization of media, stains, and staining techniques
186(6)
9.3 Classification of microbes: Actinomycetes, bacteria, rickettsiae, spirochetes, and viruses
192(3)
9.4 Nutrition, cultivation, isolation, and identification of bacteria, actinomycetes, fungi, viruses
195(2)
9.5 Control of microbes by physical and chemical methods
197(11)
9.6 Sterilization: Different methods, evaluation of sterilization methods, sterility testing of pharmaceutical products
208(5)
9.7 Conclusion
213(2)
References
213(2)
10 Application of nanotechnology in the packaging of edible materials
Abdul Wahab
Alina Abdul Rahim
Sadia Hassan
Chukwuebuka Egbuna
Muhammad Faisal Manzoor
Kelechi Justin Okere
Angelo Mark P. Walag
10.1 Introduction
215(1)
10.2 Nanoparticles with antimicrobial properties
216(2)
10.3 Methods of preparing nanoparticles
218(1)
10.4 Nanotechnology role in packaging
219(2)
10.5 Practical application of nanotechnology in food packaging
221(1)
10.6 Brief summary of the benefits of nanotechnology application in food packaging
222(1)
10.7 Conclusions
222(7)
References
223(6)
II Health benefits of nutraceuticals
11 Nutraceuticals and their impact on human health
Anand Prakash Maurya
Jaspal Chauhan
Dinesh Kumar Yadav
Reena Gangwar
Vineet Kumar Maurya
11.1 Introduction
229(1)
11.2 Types of nutraceuticals
230(10)
11.3 Difference between nutraceuticals and pharmaceuticals
240(1)
11.4 Chemical analysis of neutraceuticlas
240(1)
11.5 Health benefits of nutraceuticals
240(5)
11.6 Safety issues: Status under FDA considerations
245(3)
11.7 Advantages and limitations
248(1)
11.8 Summary
248(1)
11.9 Conclusion
249(6)
References
250(5)
12 Heart health and nutraceuticals
Shabnam Ansari
12.1 Introduction
255(1)
12.2 Current scenario of cardiovascular diseases
256(1)
12.3 Risk factors of cardiovascular diseases
256(1)
12.4 Preventive approach to cardiovascular diseases
257(1)
12.5 Nutraceuticals and current scenario
258(1)
12.6 Categories of nutraceuticals beneficial to heart
259(5)
12.7 Mechanism of action of nutraceuticals in maintaining heart health
264(4)
12.8 Summary and conclusion
268(5)
References
269(4)
13 Roles of nutraceutical in the treatment of tuberculosis
Muhammad Akram
Umme Laila
Benson Chukwunweike Ephraim-Emmanuel
Chukwuebuka Egbuna
13.1 Introduction
273(1)
13.2 Pathophysiology
274(1)
13.3 Epidemiology of tuberculosis
275(1)
13.4 Sources of vital components for health improvement
275(3)
13.5 Conclusion
278(3)
References
278(3)
14 Important food sources of nutraceuticals for the management of HIV
A. Stephen
P. Shivakumar Singh
14.1 Introduction
281(1)
14.2 Opportunistic illnesses in HIV infection
282(1)
14.3 Management of HIV and its opportunistic infections
282(1)
14.4 Food sources as nutraceuticals
283(1)
14.5 Recommended food for people with HIV/AIDS
284(1)
14.6 Conclusion
285(2)
Acknowledgments
285(1)
References
285(2)
15 Nutraceuticals for male fertility in human
Singh P. Shivakumar
G.M. Vidyasagar
15.1 Introduction
287(1)
15.2 Causes of male infertility
288(1)
15.3 Antioxidants
289(1)
15.4 Some important nutraceuticals
289(3)
15.5 Summary
292(1)
15.6 Conclusions
293(4)
References
293(4)
16 Bacteriocin producing lactic acid bacteria: Their relevance to human nutrition and health
Anand Prakash Maurya
Vineet Kumar Maurya
Ram Lal Thakur
16.1 Introduction
297(2)
16.2 Bacteriocins of LAB
299(1)
16.3 Classification
299(1)
16.4 Relevance of bacteriocin
300(1)
16.5 Summary and conclusion
301(2)
References
301(2)
17 Health-promoting benefits of honey
Merve Keskin
Saban Keskin
Sevgi Kolayli
17.1 Introduction
303(1)
17.2 History of honey
303(1)
17.3 Types of honey
303(1)
17.4 Honey composition
304(1)
17.5 Biological active properties of honey
305(1)
17.6 New products with honey used in recent years
305(1)
17.7 Conclusion
306(2)
References
306(2)
18 Biochemical and pharmacotherapeutic potentials of lycopene in drug discovery
Charles Oluwaseun Aderunji
Muhammad Akram
Andrew G. Mtewa
Jaison Jeevanandam
Chukwuebuka Egbuna
Alloysius Chibuike Ogodo
Ajay Kumar Gautam
Ashutosh Gupta
Peculiar Feenna Onyekere
Genevieve D. Tupas
Shahira M. Ezzat
Sunil Pareek
Habibu Tijjani
Nadia Sharif
Devaraj Ezhilarasan
Sadia Hassan
Narashans Alok Sagar
Abeer M. El Sayed
Mohammad Mehdizadeh
Merve Keskin
Chioma Obianuju Peculiar-Onyekere
Angelo Mark P. Walag
Priyanka Dhar
Abolanle A.A. Kayode
Ghulam Mohiudin
Khali! Ahmad
Shashank Kumar
Rida Zainab
Muhammad Kamran Khan
Muhammad Adil Farooq
Lisbeth Vallecilla-Yepez
Yusuf Abubakar
Ahmed Olarunde
18.1 Introduction
308(1)
18.2 Biosynthesis of lycopene
309(1)
18.3 Sources of lycopene
310(2)
18.4 Metabolism of lycopene
312(3)
18.5 General benefits of lycopene
315(1)
18.6 Biological activities of lycopene and its metabolites
316(16)
18.7 Hair loss and male pattern balding
332(2)
18.8 Hepatoprotective role of lycopene against various cellular abnormalities
334(3)
18.9 Lycopene in human detoxification
337(1)
18.10 Antiinfertility properties
338(1)
18.11 Lycopene: Updates on clinical trials
339(1)
18.12 Techniques for structural elucidation of lycopene
339(5)
18.13 Conclusion
344(18)
References
344(18)
19 Health benefits of glucosinolate isolated from cruciferous and other vegetables
Muhammad Akram
Farhat Jabeen
Muhammad Riaz
Fahad Said Khan
Eleonora Okushanova
Muhammad Imran
Mohammad A.H. Shariati
Tahreem Riaz
Chukwuebuka Egbuna
Nebechi Jane Ezeofor
19.1 Introduction
362(1)
19.2 Impact of glucosinolates on health
362(1)
19.3 Pharmacological properties of glucosinolates
363(6)
19.4 Conclusion
369(4)
References
370(3)
20 Glucosamine and chondroitin in osteoarthritis treatment
Andrew G. Mtewa
Amanjot Annu
Anke Weisheit
Casim U. Tolo
Patrick E. Ogwang
20.1 Introduction
373(1)
20.2 Forms of arthritis
374(1)
20.3 Diagnosis of osteoarthritis
375(1)
20.4 Treatment options to osteoarthritis
376(1)
20.5 Glucosamine and chondroitin
376(2)
20.6 Additional advantages and some known adverse events from glucosamine and chondroitin
378(1)
20.7 Conclusion
379(2)
References
379(2)
21 Phytomenadione as a dietary supplement: Sources and health benefits
I.O. Lawal
T.O. Omogbene
A.A. Adam
21.1 Introduction
381(1)
21.2 Vitamins as dietary supplements
382(1)
21.3 Vitamin K
383(4)
21.4 Conclusion
387(4)
References
387(4)
22 Application of microalgae metabolites in food and pharmaceutical industry
Neha Mishra
Ena Gupta
Priyanka Singh
Ranu Prasad
22.1 Introduction
391(1)
22.2 Promising biologically active metabolites
392(2)
22.3 Application in pharmaceutical industry
394(6)
22.4 Pharmaceutical market
400(1)
22.5 Recent trend in food industry
400(4)
22.6 Conclusion
404(6)
References
404(6)
23 Conservation and sustainable use of medicinal plants
Poonam Gusain
D.P. Uniyal
Rajappa Joga
23.1 Introduction
410(1)
23.2 Tissue culture techniques
410(1)
23.3 Seed culture
410(1)
23.4 Embryo culture
411(1)
23.5 Callus culture
412(1)
23.6 Organ culture
412(1)
23.7 Micropropagation
413(1)
23.8 Protoplast culture
413(1)
23.9 Somatic cell
414(1)
23.10 Transgenic plants
414(1)
23.11 Conservation
415(1)
23.12 Secondary metabolites
416(8)
23.13 Conclusion
424(7)
Acknowledgment
424(1)
References
424(7)
III Traditional system of medicines
24 Overview of traditional systems of medicine in different continents
Shabnam Ansari
24.1 Introduction
431(2)
24.2 Traditional systems of medicine in Asia
433(32)
24.3 Traditional system of medicine in the Americas
465(2)
24.4 Traditional system of medicine in Africa: Traditional African medicine
467(3)
24.5 Traditional system of medicine in Europe: European traditional medicine
470(1)
24.6 Conclusion
470(5)
References
471(4)
25 Perspective on herbal medicine in the Philippines, economic demands, quality control, and regulation
Genevieve D. Tupas
Laurence John Francis J. Gido
25.1 Introduction
475(1)
25.2 Herbal drug development in the Philippines
476(2)
25.3 Economic demand on herbal drugs
478(2)
25.4 Quality control and regulation
480(1)
25.5 The future of herbal medicine in the Philippines
481(2)
References
481(2)
26 Traditional system of medicines in Africa
Godwin Anywar
Chinenyenwa Ohia
Patricia A. Nalumansi
26.1 Introduction
483(1)
26.2 Traditional medicines and systems of medicine in Africa
484(1)
26.3 Scientific evidence supporting some practices and remedies in African traditional medicine systems
485(1)
26.4 Regulation of traditional and alternative systems of medicine in Africa
486(1)
26.5 Promotion of traditional system of medicines in Africa
486(1)
26.6 Assessment of quality, safety, efficacy, and intellectual property rights of TM
487(1)
26.7 Conservation of traditional medicinal plants in Africa
487(1)
26.8 Conclusion
487(4)
References
488(3)
27 Alternative and new plants
Barbara Sawicka
Dominika Skiba
Krishnan Umachandran
Adom Dickson
27.1 Introduction
491(1)
27.2 Plants replacing traditional crops
492(1)
27.3 Plants cultivated until the end of the 19th century
492(1)
27.4 New plants
493(1)
27.5 Antistress plants
493(1)
27.6 Medicinal aromatherapeutic plants (MAPs)
494(3)
27.7 Pharmacopoeial plants
497(1)
27.8 Raw materials for the production of antibodies, vaccines, and medicines
497(2)
27.9 Raw materials for the production of functional foods
499(5)
27.10 Aphrodisiac plants
504(4)
27.11 Species increasing the biological diversity of food
508(3)
27.12 Plants useful in the greening of agriculture
511(1)
27.13 Hunger plants
512(2)
27.14 Renewable raw materials for industrial purposes
514(3)
27.15 Plants in environmental protection
517(1)
27.16 Plants useful in soil biological recultivation
518(1)
27.17 Raw materials for the production of furniture, paper, and packaging
518(1)
27.18 Plants that counteract the greenhouse effect
519(2)
27.19 Cosmetic raw materials
521(2)
27.20 Plants as plant protection products
523(5)
27.21 Transgenic plants (GMO)
528(1)
27.22 Conclusion
529(10)
References
530(9)
Subject Index 539
Chukwuebuka Egbuna (PhD) is a chartered chemist and academic researcher. He is a member of the Institute of Chartered Chemists of Nigeria (ICCON), the Nigerian Society of Biochemistry and Molecular Biology (NSBMB), and the Royal Society of Chemistry (RSC) (United Kingdom). Dr. Egbuna is the founder and editor of the Elsevier book series on Drug Discovery Update. The series includes books, monographs, and edited collections from all areas of drug discovery including emerging therapeutic claims for the treatment of diseases. He has published research articles in many international journals of repute and is ranked among the top 500 Nigerian scientists in SciVal/SCOPUS. He has edited more than 25 books with Elsevier, Springer, Wiley, and Taylor & Francis. His most recent book is the three volume Coronavirus Drug Discovery, published by Elsevier. Dr. Egbuna is the founder and the publishing director of IPS Intelligentsia Publishing Services.

Abhay P. Mishra, Ph.D., is an Academic Researcher at the Department of Pharmaceutical Chemistry, Hemvati Nandan Bahuguna Garhwal University, Srinagar Garhwal-246174, Uttarakhand, India, since Sept. 2010. Prior to joining Garhwal University, he held the position of Lecturer at the Department of Pharmaceutical Chemistry, Uttaranchal College of Science and Technology, Dehradun, Uttarakhand, India. He has vast experience in the field of teaching and research. He has published many peer-reviewed scientific articles, books and presented papers at many national and international conferences. He is acting as a reviewer for many journals and has extensive professional affiliations. He is a seasoned researcher, filed an Indian patent (Published) on Nutraceutical tablet formulation from the high altitude medicinal plant of the Indian Himalayan Region. A. P. Mishra having twin interests in Phytochemistry, Natural Product Research, Analytical Method Development, and Herbal Formulation Development. He has won several academic awards. Megh R. Goyal, PhD, PE, is a Retired Professor in Agricultural and Biomedical Engineering from the General Engineering Department in the College of Engineering at University of Puerto RicoMayaguez Campus; and Senior Acquisitions Editor and Senior Technical Editor-in-Chief in Agriculture and Biomedical Engineering for Apple Academic Press Inc. He has worked as a Soil Conservation Inspector and as a Research Assistant at Haryana Agricultural University and Ohio State University. During his professional career of 45 years, he has received many prestigious awards. A prolific author and editor, he has written more than 200 journal articles and textbooks and has edited over 25 books. He received his BSc degree in engineering from Punjab Agricultural University, Ludhiana, India; his MSc and PhD degrees from Ohio State University, Columbus; and his Master of Divinity degree from Puerto Rico Evangelical Seminary, Hato Rey, Puerto Rico, USA.