This bookprovides a thorough and comprehensive reference in the management of pruritus,designed to be a convenient resource for all physicians confronted withpatients suffering from itch. The Editors have recruited a board ofinternationally renowned experts to provide an in-depth analysis of the causesand management of pruritus, including the current concepts in pathophysiologyand novel therapeutics.Acute andchronic pruritus can represent significant management issues both as a commonphysiological sensation and as a manifestation of dermatologic andnon-dermatologic diseases. All patients suffering from itch know that it is avery awkward sensation. Unfortunately, this often significant symptom isfrequently considered less severe in comparison with pain. The consequences arethat research on this field has been poorer than research on pain and thatpruritus is therefore more difficult to treat.Pruritus, Second edition addresses the new concepts anddiscoveries that ha
ve modified our understanding of this condition. It explainsthe pathophysiology of itch, describes all causes, and provides guidelines formanagement and treatment.
1. NeuralProcessing of Itch.- 2.Pruriceptors.- 3. CentralRepresentation of Itch.- 4.Interactionof Pruritus and Pain.- 5. Modulation of Pruritus: Peripheral and Central Sensitization.- 6. In vitro models of itch.- 7. Measurement of Sensory Function in Chronic Pruritus.- 8. Pruritus,Pain and Other Abnormal Skin Sensations.- 9. Epidemiology.- 10. Classification.- 11. Examinationof Patients.- 12. Measurement of Itch: Patient-Reported Outcomes.- 13. Measurementof Itch: Actigraphy.- 14. Placeboand Nocebo Effects on Itch: Methodological and Clinical Implications.- 15. PatientNeeds and Treatment Goals in Clinical Care of Chronic Pruritus.- 16. Sex-and Gender-Specific Differences in Chronic Pruritus.- 17. ClinicalPresentation of Itch.- 18. SensitiveSkin.- 19. Atopic Dermatitis.- 20. Allergicand Irritant Contact Dermatitis.- 21. Urticaria.- 22.Mastocytosis.- 23. CutaneousDrug Reactions and Drug-Induced Pruritus.- 24. Psoriasis.- 25. AutoimmuneDiseases.- 26. Itch,Infections an
d Infestations.- 27. CutaneousLymphoma.- 28. NeuropathicPruritus.- 29. Notalg aParesthet ca.- 30. BrachioradialPruritus.- 31. OtherForms of Neuropathic Pruritus.- 32. Small-FibreNeuropathies.- 33. ChronicKidney Diseases.- 34.HepatobiliaryDiseases.- 35. EndocrineDiseases.- 36. Pruritusin Hematological Diseases (Including Aquagenic Pruritus).- 37. Cancers.- 38. TheBurden Of Itch.- 39. PsychologicalApproach.- 40. PsychosomaticAspects and Psychiatric Conditions.- 41. PsychogenicPruritus..- 42. Pruritusin Children.- 43. PruritusVulvae.- 44.GeneralPrinciples and Guidelines.- 45. Capsaicin.- 46. TopicalSteroids and Immunomodulators.- 47. Menthol, Camphor and Other Topical Treatments.- 48. Antihistamines.- 49. Anticonvulsants.- 50. OpioidReceptor Antagonists or Agonists.- 51. Antidepressants.- 52. Immunosuppressants.- 53. NK-1Antagonists.- 54. PsychologicalIntervention.- 55. UltravioletPhototherapy of Pruritus.- 56. Acupuncture.- 57.Future Perspectives: New and Moder
n Therapies.-