Preface |
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vii | |
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Chapter 1 Function and Structure of the Respiratory System |
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1 | (11) |
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1 | (1) |
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Functions of the Respiratory System |
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1 | (2) |
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Structure of the Respiratory System |
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3 | (7) |
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10 | (1) |
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11 | (1) |
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Chapter 2 Mechanics of Breathing |
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12 | (46) |
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12 | (1) |
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Generation of a Pressure Difference Between Atmosphere and Alveoli |
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13 | (8) |
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Pressure-Volume Relationships in the Respiratory System |
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21 | (10) |
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Interaction of Lung and Chest Wall: The Static Pressure-Volume Curve |
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31 | (2) |
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33 | (19) |
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52 | (1) |
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53 | (1) |
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54 | (3) |
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57 | (1) |
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Chapter 3 Alveolar Ventilation |
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58 | (33) |
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58 | (1) |
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58 | (3) |
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Measurement of the Lung Volumes |
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61 | (8) |
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Anatomic Dead Space and Alveolar Ventilation |
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69 | (1) |
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Measurement of Alveolar Ventilation |
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70 | (5) |
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Alveolar Ventilation and Alveolar Oxygen and Carbon Dioxide Levels |
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75 | (4) |
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Regional Distribution of Alveolar Ventilation |
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79 | (4) |
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83 | (2) |
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85 | (1) |
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86 | (1) |
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87 | (3) |
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90 | (1) |
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Chapter 4 Blood Flow to the Lung |
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91 | (29) |
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91 | (1) |
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The Bronchial Circulation |
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92 | (1) |
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The Functional Anatomy of the Pulmonary Circulation |
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93 | (4) |
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Pulmonary Vascular Resistance |
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97 | (7) |
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The Regional Distribution of Pulmonary Blood Flow: The Zones of the Lung |
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104 | (7) |
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Hypoxic Pulmonary Vasoconstriction |
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111 | (2) |
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113 | (3) |
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116 | (1) |
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117 | (2) |
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119 | (1) |
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Chapter 5 Ventilation-Perfusion Relationships |
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120 | (18) |
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120 | (1) |
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The Concept of Matching Ventilation and Perfusion |
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120 | (1) |
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Consequences of High and Low V/Q |
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121 | (2) |
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Testing for Nonuniform Distribution of Inspired Gas and Pulmonary Blood Flow |
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123 | (9) |
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Regional V/Q Differences and Their Consequences in the Lung |
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132 | (3) |
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135 | (1) |
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135 | (2) |
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137 | (1) |
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Chapter 6 Diffusion of Gases and Interpretation of Pulmonary Function Tests |
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138 | (15) |
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138 | (1) |
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139 | (2) |
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Limitations of Gas Transfer |
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141 | (2) |
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143 | (2) |
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Diffusion of Carbon Dioxide |
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145 | (1) |
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Measurement of Diffusing Capacity |
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145 | (3) |
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Interpretation of Pulmonary Function Tests |
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148 | (2) |
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150 | (1) |
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150 | (2) |
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152 | (1) |
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Chapter 7 Transport of Oxygen and Carbon Dioxide in the Blood |
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153 | (22) |
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153 | (1) |
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Transport of Oxygen by the Blood |
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153 | (3) |
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Hemoglobin and the Physiologic Implications of the Oxyhemoglobin Dissociation Curve |
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156 | (4) |
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Influences on the Oxyhemoglobin Dissociation Curve |
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160 | (7) |
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Transport of Carbon Dioxide by the Blood |
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167 | (3) |
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The Carbon Dioxide Dissociation Curve |
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170 | (1) |
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The Bohr and Haldane Effects Explained |
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170 | (2) |
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172 | (1) |
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172 | (2) |
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174 | (1) |
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Chapter 8 Acid-Base Balance |
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175 | (27) |
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175 | (1) |
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The Chemistry of Acids, Bases, and Buffers |
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175 | (3) |
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Buffer Systems of the Human Body |
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178 | (5) |
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183 | (5) |
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Respiratory and Renal Compensatory Mechanisms |
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188 | (2) |
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Clinical Interpretation of Blood Gases and Acid-Base Status |
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190 | (3) |
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193 | (3) |
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196 | (1) |
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197 | (4) |
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201 | (1) |
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Chapter 9 Control of Breathing |
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202 | (28) |
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202 | (1) |
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The Generation of Spontaneous Rhythmicity |
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203 | (2) |
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The Medullary Respiratory Center |
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205 | (2) |
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The Pontine Respiratory Groups |
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207 | (1) |
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207 | (1) |
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Reflex Mechanisms of Respiratory Control |
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208 | (5) |
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Influences of Higher Centers |
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213 | (1) |
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The Response to Carbon Dioxide |
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214 | (7) |
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The Response to Hydrogen Ions |
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221 | (1) |
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222 | (1) |
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223 | (3) |
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226 | (1) |
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227 | (1) |
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228 | (2) |
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Chapter 10 Nonrespiratory Functions of the Lung |
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230 | (15) |
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230 | (1) |
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Pulmonary Defense Mechanisms |
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230 | (7) |
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Nonrespiratory Functions of the Pulmonary Circulation |
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237 | (2) |
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Metabolic Functions of the Lung |
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239 | (3) |
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242 | (2) |
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244 | (1) |
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Chapter 11 The Respiratory System Under Stress |
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245 | (43) |
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245 | (1) |
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Exercise and the Respiratory System |
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245 | (7) |
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Altitude and Acclimatization |
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252 | (7) |
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Diving and the Respiratory System |
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259 | (7) |
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Sleep and the Respiratory System |
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266 | (1) |
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267 | (1) |
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268 | (4) |
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272 | (16) |
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275 | (13) |
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288 | (5) |
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I Symbols Used in Respiratory Physiology |
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288 | (1) |
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II The Laws Governing the Behavior of Gases |
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288 | (1) |
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III Frequently Used Equations |
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289 | (1) |
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IV Table of Normal Respiratory and Circulatory Values |
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290 | (1) |
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V General Suggested Readings |
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291 | (2) |
Index |
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293 | |