Preface |
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vii | |
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Chapter 1 Function and Structure of the Respiratory System |
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1 | (11) |
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Functions of the Respiratory System |
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1 | (3) |
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Structure of the Respiratory System |
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4 | (7) |
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11 | (1) |
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11 | (1) |
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Chapter 2 Mechanics of Breathing |
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12 | (47) |
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Generation of a Pressure Difference Between Atmosphere and Alveoli |
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13 | (8) |
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Pressure-Volume Relationships in the Respiratory System |
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21 | (10) |
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Interaction of Lung and Chest Wall: The Static Pressure-Volume Curve |
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31 | (4) |
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35 | (18) |
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53 | (2) |
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55 | (1) |
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55 | (3) |
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58 | (1) |
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Chapter 3 Alveolar Ventilation |
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59 | (35) |
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59 | (3) |
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Measurement of the Lung Volumes |
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62 | (8) |
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Anatomic Dead Space and Alveolar Ventilation |
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70 | (2) |
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Measurement of Alveolar Ventilation |
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72 | (5) |
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Alveolar Ventilation and Alveolar Oxygen and Carbon Dioxide Levels |
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77 | (4) |
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Regional Distribution of Alveolar Ventilation |
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81 | (4) |
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85 | (2) |
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87 | (2) |
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89 | (1) |
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89 | (3) |
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92 | (2) |
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Chapter 4 Blood Flow to the Lung |
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94 | (30) |
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The Bronchial Circulation |
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95 | (2) |
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The Functional Anatomy of the Pulmonary Circulation |
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97 | (3) |
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Pulmonary Vascular Resistance |
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100 | (7) |
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The Regional Distribution of Pulmonary Blood Flow: The Zones of the Lung |
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107 | (7) |
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Hypoxic Pulmonary Vasoconstriction |
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114 | (2) |
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Effects of Mechanical Ventilation on Pulmonary Blood Flow |
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116 | (1) |
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117 | (3) |
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120 | (1) |
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121 | (1) |
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122 | (2) |
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Chapter 5 Ventilation-Perfusion Relationships |
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124 | (18) |
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The Concept of Matching Ventilation and Perfusion |
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124 | (1) |
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Consequences of High and Low V/Q |
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125 | (2) |
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Testing for Nonuniform Distribution of Inspired Gas and Pulmonary Blood Flow |
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127 | (9) |
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Regional V/Q Differences and Their Consequences in the Lung |
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136 | (3) |
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139 | (1) |
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139 | (2) |
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141 | (1) |
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Chapter 6 Diffusion of Gases and Interpretation of Pulmonary Function Tests |
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142 | (15) |
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143 | (2) |
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Limitations of Gas Transfer |
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145 | (2) |
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147 | (2) |
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Diffusion of Carbon Dioxide |
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149 | (1) |
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Measurement of Diffusing Capacity |
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149 | (3) |
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Interpretation of Pulmonary Function Tests |
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152 | (2) |
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154 | (1) |
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154 | (2) |
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156 | (1) |
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Chapter 7 Transport of Oxygen and Carbon Dioxide in the Blood |
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157 | (22) |
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Transport of Oxygen by the Blood |
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157 | (3) |
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Hemoglobin and the Physiologic Implications of the Oxyhemoglobin Dissociation Curve |
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160 | (4) |
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Influences on the Oxyhemoglobin Dissociation Curve |
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164 | (7) |
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Transport of Carbon Dioxide by the Blood |
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171 | (2) |
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The Carbon Dioxide Dissociation Curve |
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173 | (1) |
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The Bohr and Haldane Effects Explained |
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174 | (2) |
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176 | (1) |
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176 | (2) |
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178 | (1) |
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Chapter 8 Acid-Base Balance |
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179 | (27) |
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The Chemistry of Acids, Bases, and Buffers |
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179 | (3) |
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Buffer Systems of the Human Body |
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182 | (6) |
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188 | (4) |
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Respiratory and Renal Compensatory Mechanisms |
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192 | (2) |
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Clinical Interpretation of Blood Gases and Acid-Base Status |
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194 | (3) |
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197 | (3) |
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200 | (1) |
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201 | (4) |
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205 | (1) |
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Chapter 9 Control of Breathing |
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206 | (29) |
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The Generation of Spontaneous Rhythmicity |
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207 | (2) |
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The Medullary Respiratory Center |
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209 | (2) |
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The Pontine Respiratory Groups |
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211 | (1) |
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211 | (1) |
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Reflex Mechanisms of Respiratory Control |
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212 | (5) |
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Influences of Higher Centers |
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217 | (1) |
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The Response to Carbon Dioxide |
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218 | (8) |
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The Response to Hydrogen Ions |
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226 | (1) |
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227 | (1) |
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227 | (4) |
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231 | (1) |
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231 | (2) |
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233 | (2) |
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Chapter 10 Nonrespiratory Functions of the Lung |
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235 | (15) |
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Pulmonary Defense Mechanisms |
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235 | (7) |
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Nonrespiratory Functions of the Pulmonary Circulation |
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242 | (2) |
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Metabolic Functions of the Lung |
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244 | (3) |
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247 | (2) |
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249 | (1) |
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Chapter 11 The Respiratory System Under Stress |
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250 | (44) |
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Exercise and the Respiratory System |
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250 | (7) |
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Altitude and Acclimatization |
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257 | (7) |
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Diving and the Respiratory System |
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264 | (7) |
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Sleep and the Respiratory System |
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271 | (2) |
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273 | (1) |
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273 | (5) |
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278 | (16) |
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281 | (13) |
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294 | (3) |
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I Symbols used in Respiratory Physiology |
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294 | (1) |
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II The Laws Governing the Behavior of Gases |
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294 | (1) |
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III Frequently used Equations |
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295 | (1) |
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IV Table of Normal Respiratory and Circulatory Values |
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296 | (1) |
Index |
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297 | |