Preface |
|
vii | |
|
Chapter 1 Function and Structure of the Respiratory System |
|
|
1 | (11) |
|
Functions of the Respiratory System |
|
|
1 | (3) |
|
Structure of the Respiratory System |
|
|
4 | (7) |
|
|
11 | (1) |
|
|
11 | (1) |
|
Chapter 2 Mechanics of Breathing |
|
|
12 | (48) |
|
Generation of a Pressure Difference Between Atmosphere and Alveoli |
|
|
13 | (8) |
|
Pressure-Volume Relationships in the Respiratory System |
|
|
21 | (11) |
|
Interaction of Lung and Chest Wall: The Static Pressure-Volume Curve |
|
|
32 | (3) |
|
|
35 | (19) |
|
|
54 | (1) |
|
|
55 | (1) |
|
|
56 | (2) |
|
|
58 | (2) |
|
Chapter 3 Alveolar Ventilation |
|
|
60 | (35) |
|
|
60 | (3) |
|
Measurement of the Lung Volumes |
|
|
63 | (8) |
|
Anatomic Dead Space and Alveolar Ventilation |
|
|
71 | (2) |
|
Measurement of Alveolar Ventilation |
|
|
73 | (5) |
|
Alveolar Ventilation and Alveolar Oxygen and Carbon Dioxide Levels |
|
|
78 | (4) |
|
Regional Distribution of Alveolar Ventilation |
|
|
82 | (4) |
|
|
86 | (2) |
|
|
88 | (2) |
|
|
90 | (1) |
|
|
90 | (3) |
|
|
93 | (2) |
|
Chapter 4 Blood Flow to the Lung |
|
|
95 | (30) |
|
The Bronchial Circulation |
|
|
96 | (2) |
|
The Functional Anatomy of the Pulmonary Circulation |
|
|
98 | (3) |
|
Pulmonary Vascular Resistance |
|
|
101 | (7) |
|
The Regional Distribution of Pulmonary Blood Flow: The Zones of the Lung |
|
|
108 | (7) |
|
Hypoxic Pulmonary Vasoconstriction |
|
|
115 | (2) |
|
Effects of Mechanical Ventilation on Pulmonary Blood Flow |
|
|
117 | (1) |
|
|
118 | (3) |
|
|
121 | (1) |
|
|
122 | (1) |
|
|
123 | (2) |
|
Chapter 5 Ventilation-Perfusion Relationships |
|
|
125 | (20) |
|
The Concept of Matching Ventilation and Perfusion |
|
|
125 | (1) |
|
Consequences of High and Low V/Q |
|
|
126 | (2) |
|
Testing for Nonuniform Distribution of Inspired Gas and Pulmonary Blood Flow |
|
|
128 | (10) |
|
Regional V/Q Differences and Their Consequences in the Lung |
|
|
138 | (4) |
|
|
142 | (1) |
|
|
142 | (2) |
|
|
144 | (1) |
|
Chapter 6 Diffusion of Gases and Interpretation of Pulmonary Function Tests |
|
|
145 | (15) |
|
|
146 | (2) |
|
Limitations of Gas Transfer |
|
|
148 | (2) |
|
|
150 | (2) |
|
Diffusion of Carbon Dioxide |
|
|
152 | (1) |
|
Measurement of Diffusing Capacity |
|
|
152 | (3) |
|
Interpretation of Pulmonary Function Tests |
|
|
155 | (2) |
|
|
157 | (1) |
|
|
157 | (2) |
|
|
159 | (1) |
|
Chapter 7 Transport of Oxygen and Carbon Dioxide in the Blood |
|
|
160 | (22) |
|
Transport of Oxygen by the Blood |
|
|
160 | (3) |
|
Hemoglobin and the Physiologic Implications of the Oxyhemoglobin Dissociation Curve |
|
|
163 | (4) |
|
Influences on the Oxyhemoglobin Dissociation Curve |
|
|
167 | (7) |
|
Transport of Carbon Dioxide by the Blood |
|
|
174 | (2) |
|
The Carbon Dioxide Dissociation Curve |
|
|
176 | (1) |
|
The Bohr and Haldane Effects Explained |
|
|
177 | (2) |
|
|
179 | (1) |
|
|
179 | (2) |
|
|
181 | (1) |
|
Chapter 8 Acid-Base Balance |
|
|
182 | (27) |
|
The Chemistry of Acids, Bases, and Buffers |
|
|
182 | (3) |
|
Buffer Systems of the Human Body |
|
|
185 | (6) |
|
|
191 | (4) |
|
Respiratory and Renal Compensatory Mechanisms |
|
|
195 | (2) |
|
Clinical Interpretation of Blood Gases and Acid-Base Status |
|
|
197 | (3) |
|
|
200 | (3) |
|
|
203 | (1) |
|
|
204 | (4) |
|
|
208 | (1) |
|
Chapter 9 Control of Breathing |
|
|
209 | (29) |
|
The Generation of Spontaneous Rhythmicity |
|
|
210 | (2) |
|
The Medullary Respiratory Center |
|
|
212 | (2) |
|
The Pontine Respiratory Groups |
|
|
214 | (1) |
|
|
214 | (1) |
|
Reflex Mechanisms of Respiratory Control |
|
|
215 | (5) |
|
Influences of Higher Centers |
|
|
220 | (1) |
|
The Response to Carbon Dioxide |
|
|
221 | (8) |
|
The Response to Hydrogen Ions |
|
|
229 | (1) |
|
|
230 | (1) |
|
|
230 | (4) |
|
Altered Breathing Patterns |
|
|
234 | (1) |
|
|
234 | (1) |
|
|
235 | (1) |
|
|
236 | (2) |
|
Chapter 10 Nonrespiratory Functions of the Lung |
|
|
238 | (15) |
|
Pulmonary Defense Mechanisms |
|
|
238 | (7) |
|
Nonrespiratory Functions of the Pulmonary Circulation |
|
|
245 | (2) |
|
Metabolic Functions of the Lung |
|
|
247 | (3) |
|
|
250 | (2) |
|
|
252 | (1) |
|
Chapter 11 The Respiratory System Under Stress |
|
|
253 | (44) |
|
Exercise and the Respiratory System |
|
|
253 | (7) |
|
Altitude and Acclimatization |
|
|
260 | (7) |
|
Diving and the Respiratory System |
|
|
267 | (7) |
|
Sleep and the Respiratory System |
|
|
274 | (2) |
|
|
276 | (1) |
|
|
276 | (5) |
|
|
281 | (3) |
|
|
284 | (13) |
|
|
297 | (4) |
|
I Symbols Used in Respiratory Physiology |
|
|
297 | (1) |
|
II The Laws Governing the Behavior of Gases |
|
|
297 | (1) |
|
III Frequently Used Equations |
|
|
298 | (1) |
|
IV Table of Normal Respiratory and Circulatory Values |
|
|
299 | (2) |
Index |
|
301 | |