Summary of Major Changes in the 2018 Red Book |
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xxxv | |
Section 1 Active And Passive Immunization |
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1 | (2) |
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Sources of Information About Immunization |
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3 | (4) |
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Discussing Vaccines With Patients and Parents |
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7 | (6) |
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Addressing Parents' Questions About Vaccine Safety and Effectiveness |
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7 | (1) |
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Common Misconceptions About Immunizations and the Institute of Medicine Findings |
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7 | (1) |
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Resources for Optimizing Communications With Parent About Vaccines |
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8 | (3) |
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Parental Refusal of Immunizations |
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11 | (2) |
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13 | (42) |
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17 | (3) |
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Vaccine Handling and Storage |
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20 | (6) |
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26 | (4) |
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30 | (1) |
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Timing of Vaccine's and the Immunization Schedule |
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31 | (3) |
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Minimum Ages and Minimum Intervals Between Vaccine Doses |
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34 | (1) |
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Interchangeability of Vaccine Products |
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34 | (1) |
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Simultaneous Administration of Multiple Vaccines |
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35 | (1) |
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36 | (2) |
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38 | (1) |
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Unknown or Uncertain Immunization Status |
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38 | (1) |
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38 | (1) |
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Active Immunization of People Who Recently Received Immune Globulin and Other Blood Products |
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39 | (2) |
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41 | (14) |
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41 | (2) |
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Institute of Medicine Reviews of Adverse Events After Immunization |
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43 | (2) |
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Vaccine Adverse Event Reporting System |
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45 | (1) |
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Vaccine Safety Datalink Project |
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46 | (3) |
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Post-Licensure Rapid Immunization Safety Monitoring (PRISM) |
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49 | (1) |
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Clinical Immunization Safety Assessment (LISA) Project |
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50 | (1) |
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Vaccine Injury Compensation |
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51 | (1) |
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Hypersensitivity Reactions After Immunization |
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52 | (1) |
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Immediate-Type Allergic Reactions |
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53 | (1) |
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Delayed-Type Allergic Reactions |
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54 | (1) |
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54 | (1) |
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55 | (12) |
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Immune Globulin Intramuscular (IGIM) |
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56 | (2) |
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Immune Globulin Intravenous (IG1V) |
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58 | (4) |
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Immune Globulin Subcutaneous (IGSC) |
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62 | (2) |
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Treatment of Anaphylactic Reactions |
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64 | (3) |
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Immunization in Special Clinical Circumstances |
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67 | (46) |
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Immunization in Preterm and Low Birth Weight Infants |
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67 | (2) |
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Immunization in Pregnancy |
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69 | (3) |
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Immunization and Other Considerations in Immunocompromised Children |
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72 | (19) |
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Immunization in Children With a Personal or Family History of Seizures |
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91 | (1) |
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Immunization in Children With Chronic Diseases |
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92 | (1) |
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Immunization in American Indian/Alaska Native Children and Adolescents |
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93 | (2) |
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Immunization in Adolescent and College Populations |
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95 | (2) |
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Immunization in Health Care Personnel |
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97 | (3) |
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Children Who Received Immunizations Outside the United States or Whose Immunization Status is Unknown or Uncertain |
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100 | (3) |
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103 | (10) |
Section 2 Recommendations For Care Of Children In Special Circumstances |
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113 | (9) |
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Immunization of Mothers and Infants |
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114 | (1) |
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Transmission of Infectious Agents via Human Milk |
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115 | (6) |
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Antimicrobial Agents and Other Drugs in Human Milk |
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121 | (1) |
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Biologic Response Modifiers in Human Milk |
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121 | (1) |
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Children in Out-of-Home Child Care |
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122 | (14) |
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Modes of Spread of Infectious Diseases |
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122 | (3) |
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Management and Prevention of Infectious Diseases |
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125 | (11) |
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136 | (11) |
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Diseases Preventable by Routine Childhood Immunization |
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138 | (2) |
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Infections Spread by the Respiratory Route |
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140 | (1) |
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Infections Spread by Direct Contact |
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141 | (2) |
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Infections Spread by the Fecal-Oral Route |
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143 | (1) |
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Infections Spread by Blood and Body Fluids |
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144 | (3) |
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Infection Control and Prevention for Hospitalized Children |
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147 | (16) |
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148 | (10) |
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Strategies to Prevent Health Care-Associated Infections |
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158 | (1) |
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159 | (1) |
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160 | (1) |
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161 | (1) |
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161 | (2) |
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Infection Control and Prevention in Ambulatory Settings |
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163 | (2) |
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Sexually Transmitted Infections in Adolescents and Children |
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165 | (11) |
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165 | (3) |
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168 | (8) |
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Medical Evaluation for Infectious Diseases for Internationally Adopted, Refugee, and Immigrant Children |
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176 | (9) |
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Consideration for Testing for Infectious Agents |
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178 | (7) |
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178 | (1) |
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179 | (1) |
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179 | (1) |
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180 | (1) |
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Tissue Parasites/Eosinophilia |
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181 | (1) |
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181 | (1) |
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182 | (1) |
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183 | (1) |
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Chagas Disease (American Trypanosomiasis) |
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183 | (1) |
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Other Infectious Diseases |
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184 | (1) |
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Injuries From Discarded Needles in the Community |
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185 | (4) |
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Wound Care and Tetanus Prophylaxis |
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186 | (1) |
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186 | (3) |
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Preventing Needlestick Injuries |
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189 | (1) |
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189 | (6) |
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Prevention of Mosquitoborne and Tickborne Infections |
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195 | (6) |
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General Protective Measures |
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196 | (1) |
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Repellents for Use on Skin |
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197 | (3) |
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Tick Inspection and Removal |
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200 | (1) |
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Other Preventive Measures |
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200 | (1) |
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Prevention of Illnesses Associated with Recreational Water Use |
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201 | (4) |
Section 3 Summaries Of Infectious Diseases |
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205 | (1) |
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206 | (2) |
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208 | (3) |
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Amebic Meningoencephalitis and Keratitis |
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211 | (3) |
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214 | (6) |
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220 | (7) |
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Arcanobacterium haemolyticum Infections |
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227 | (1) |
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Ascaris lumbricoides Infections |
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228 | (2) |
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230 | (4) |
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234 | (1) |
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235 | (2) |
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Bacillus cereus Infections and Intoxications |
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237 | (2) |
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239 | (3) |
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Bacteroides, Prevotella, and Other Anaerobic Gram-Negative Bacilli Infections |
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242 | (1) |
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Balantidium coli Infections (Balantidiasis) |
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243 | (1) |
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Bartonella henselae (Cat-Scratch Disease) |
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244 | (3) |
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247 | (1) |
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Infections With Blastocystis hominis and Other Subtypes |
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248 | (1) |
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249 | (2) |
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251 | (1) |
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Borrelia Infections Other Than Lyme Disease (Relapsing Fever) |
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252 | (3) |
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255 | (3) |
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258 | (2) |
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260 | (3) |
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263 | (6) |
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Chancroid and Cutaneous Ulcers |
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269 | (2) |
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271 | (2) |
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273 | (10) |
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273 | (1) |
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Chlamydia psittaci (Psittacosis, Ornithosis, Parrot Fever) |
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274 | (2) |
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276 | (7) |
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283 | (11) |
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Botulism and Infant Botulism (Clostridium botulinum) |
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283 | (3) |
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Clostridial Myonecrosis (Gas Gangrene) |
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286 | (2) |
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288 | (4) |
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Clostridium peringens Food Poisoning |
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292 | (2) |
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294 | (3) |
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Coronaviruses, Including SARS and MERS |
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297 | (4) |
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Cryptococcus neoformans and Cryptococcus gattii Infections (Cryptococcosis) |
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301 | (3) |
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304 | (3) |
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307 | (1) |
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308 | (1) |
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Cystoisosporiasis (Formerly Isosporiasis) |
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309 | (1) |
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Cytomegalovirus Infection |
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310 | (7) |
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317 | (2) |
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319 | (4) |
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Ehrlichia, Anaplasma, and Related Infections (Human Ehrlichiosis, Anaplasmosis, and Related Infections Attributable to Bacteria in the Family Anaplasmataceae) |
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323 | (5) |
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Serious Bacterial Infections Caused by Enterobacteriaceae (With Emphasis on Septicemia and Meningitis in Neonates) |
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328 | (3) |
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Enterovirus (Nonpoliovirus) (Group A and B Coxsackieviruses, Echoviruses, Numbered Enteroviruses) |
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331 | (3) |
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Epstein-Barr Virus Infections (Infectious Mononucleosis) |
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334 | (4) |
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Escherichia coli Diarrhea (Including Hemolytic-Uremic Syndrome) |
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338 | (6) |
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344 | (6) |
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Fusobacterium Infections (Including Lemierre Disease) |
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350 | (2) |
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Giardia intestinalis (formerly Giardia lamblia and Giardia duodenalis) Infections (Giardiasis) |
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352 | (3) |
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355 | (10) |
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Granuloma Inguinale (Donovanosis) |
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365 | (2) |
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Haemophilus influenzae Infections |
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367 | (8) |
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Hantavirus Pulmonary Syndrome |
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375 | (3) |
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Helicobacter pylori Infections |
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378 | (3) |
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Hemorrhagic Fevers Caused by Arenaviruses |
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381 | (3) |
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Hemorrhagic Fevers Caused by Bunyaviruses |
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384 | (3) |
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Hemorrhagic Fevers Caused by Filoviruses: Ebola and Marburg |
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387 | (5) |
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392 | (9) |
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401 | (27) |
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428 | (6) |
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434 | (2) |
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436 | (1) |
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437 | (12) |
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449 | (4) |
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Hookworm Infections (Ancylostoma duodenale and Necator americanus) |
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453 | (1) |
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Human Herpesvirus 6 (Including Roseola) and 7 |
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454 | (3) |
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457 | (2) |
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Human Immunodeficiency Virus Infection |
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459 | (17) |
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476 | (14) |
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490 | (7) |
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Kingella kingae Infections |
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497 | (1) |
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Legionella pneumophila Infections |
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498 | (3) |
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501 | (3) |
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504 | (4) |
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508 | (3) |
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Listeria monocytogenes Infections (Listeriosis) |
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511 | (4) |
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Lyme Disease (Lyme Borreliosis, Borrelia burgdoeri sensu lato Infection) |
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515 | (8) |
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Lymphatic Filariasis (Bancroftian, Malayan, and Timorian) |
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523 | (2) |
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Lymphocytic Choriomeningitis |
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525 | (2) |
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527 | (10) |
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537 | (13) |
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550 | (11) |
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561 | (2) |
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Microsporidia Infections (Microsporidiosis) |
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563 | (2) |
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565 | (1) |
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Moraxella catarrhalis Infections |
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566 | (1) |
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567 | (6) |
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Mycoplasma pneumoniae and Other Mycoplasma Species Infections |
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573 | (2) |
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575 | (2) |
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Norovirus and Sapovirus Infections |
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577 | (3) |
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Onchocerciasis (River Blindness, Filariasis) |
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580 | (2) |
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582 | (8) |
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Paracoccidioidomycosis (Formerly Known as South American Blastomycosis) |
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590 | (1) |
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591 | (2) |
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Parainfluenza Viral Infections |
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593 | (2) |
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595 | (6) |
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Human Parechovirus Infections |
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601 | (1) |
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Parvovirus B19 (Erythema Infectiosum, Fifth Disease) |
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602 | (4) |
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606 | (1) |
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Pediculosis Capitis (Head Lice) |
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607 | (5) |
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Pediculosis Corporis (Body Lice) |
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612 | (1) |
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Pediculosis Pubis (Pubic Lice, Crab Lice) |
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613 | (1) |
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Pelvic Inflammatory Disease |
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614 | (6) |
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Pertussis (Whooping Cough) |
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620 | (14) |
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Pinworm Infection (Enterobius vermiculaiis) |
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634 | (1) |
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Pityriasis Versicolor (Formerly Tinea Versicolor) |
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635 | (2) |
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637 | (2) |
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639 | (12) |
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Pneumocystis jirovecii Infections |
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651 | (6) |
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657 | (7) |
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Polyomaviruses (BK, JC, and Other Polyomaviruses) |
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664 | (2) |
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Prion Diseases: Transmissible Spongiform Encephalopathies |
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666 | (5) |
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Q Fever (Coxiella burnetii Infection) |
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671 | (2) |
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673 | (7) |
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680 | (2) |
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Respiratory Syncytial Virus |
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682 | (10) |
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692 | (1) |
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693 | (3) |
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696 | (1) |
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Rocky Mountain Spotted Fever |
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697 | (3) |
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700 | (5) |
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705 | (6) |
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711 | (7) |
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718 | (3) |
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721 | (2) |
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723 | (4) |
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727 | (3) |
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730 | (2) |
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Staphylococcal Food Poisoning |
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732 | (1) |
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733 | (13) |
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Coagulase-Negative Staphylococcal Infections |
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746 | (2) |
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Group A Streptococcal Infections |
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748 | (14) |
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Group B Streptococcal Infections |
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762 | (6) |
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Non-Group A or B Streptococcal and Enterococcal Infections |
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768 | (4) |
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Strongyloidiasis (Strongyloides stercoralis) |
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772 | (1) |
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773 | (15) |
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Tapeworm Diseases (Taeniasis and Cysticercosis) |
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788 | (3) |
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Other Tapeworm Infections (Including Hydatid Disease) |
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791 | (2) |
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793 | (5) |
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Tinea Capitis (Ringworm of the Scalp) |
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798 | (3) |
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Tinea Corporis (Ringworm of the Body) |
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801 | (3) |
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804 | (2) |
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Tinea Pedis and Tinea Unguium (Onychomycosis) (Athlete's Foot, Ringworm of the Feet) |
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806 | (2) |
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Toxocariasis (Visceral Toxocariasis [ a Form of Visceral Larva Migrans], Ocular Toxocariasis [ a Form of Ocular Larva Migrans]) |
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808 | (1) |
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Toxoplasma gondii Infections (Toxoplasmosis) |
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809 | (10) |
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Trichinellosis (Trichinella spiralis and Other Species) |
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819 | (1) |
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Trichomonas vaginalis Infections (Trichomoniasis) |
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820 | (3) |
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Trichuriasis (Whipworm Infection) |
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823 | (1) |
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African Trypanosomiasis (African Sleeping Sickness) |
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824 | (2) |
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American Trypanosomiasis (Chagas Disease) |
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826 | (3) |
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829 | (24) |
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Nontuberculous Mycobacteria (Environmental Mycobacteria, Mycobacteria Other Than Mycobacterium tuberculosis) |
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853 | (8) |
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861 | (3) |
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Endemic Typhus (Murine Typhus) |
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864 | (1) |
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Epidemic Typhus (Louseborne or Sylvatic Typhus) |
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865 | (2) |
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Ureaplasma urealyticum and Ureaplasma parvum Infections |
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867 | (2) |
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Varicella-Zoster Virus Infections |
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869 | (14) |
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883 | (5) |
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Cholera (Vibrio cholerae) |
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883 | (4) |
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887 | (1) |
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888 | (3) |
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Yersinia enterocolitica and Yersinia pseudotuberculosis Infections (Enteritis and Other Illnesses) |
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891 | (3) |
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894 | (9) |
Section 4 Antimicrobial Agents And Related Therapy |
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903 | (3) |
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904 | (1) |
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905 | (1) |
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906 | (1) |
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Antimicrobial Resistane and Antimicrobial Stewardship: Appropriate and Judicious Use of Antimicrobial Agents |
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906 | (7) |
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906 | (1) |
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Factors Contributing to Resistance |
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907 | (1) |
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Antimicrobial Resistance Threats |
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907 | (1) |
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Actions to Prevent or Slow Antimicrobial Resistance |
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908 | (1) |
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Antimicrobial Stewardship |
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909 | (1) |
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Role of the Medical Provider |
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910 | (1) |
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Principles of Appropriate Use of Antimicrobial Therapy for Upper Respiratory Tract Infections |
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910 | (3) |
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913 | (1) |
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Tables of Antibacterial Drug Dosages |
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914 | (19) |
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Sexually Transmitted Infections |
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933 | (5) |
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Antifungal Drugs for Systemic Fungal Infections |
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938 | (7) |
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938 | (2) |
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940 | (1) |
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940 | (1) |
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941 | (4) |
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Recommended Doses of Parenteral and Oral Antifungal Drugs |
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945 | (11) |
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Topical Drugs for Superficial Fungal Infections |
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956 | (10) |
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966 | (19) |
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Drugs for Parasitic Infections |
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985 | (41) |
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MedWatch-The FDA Safety Information and Adverse Event-Reporting Program |
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1026 | (3) |
Section 5 Antimicrobial Prophylaxis |
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Antimicrobial Prophylaxis |
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1029 | (2) |
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Infection-Prone Body Sites |
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1029 | (2) |
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Exposure to Specific Pathogens |
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1031 | (1) |
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1031 | (1) |
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Antimicrobial Prophylaxis in Pediatric Surgical Patients |
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1031 | (13) |
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Guidelines for Appropriate Use |
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1032 | (1) |
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Indications for Prophylaxis |
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1032 | (2) |
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Surgical Site Infection Criteria |
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1034 | (1) |
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Timing of Administration of Prophylactic Antimicrobial Agents |
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1035 | (1) |
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Dosing and Duration of Administration of Antimicrobial Agents |
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1035 | (1) |
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Preoperative Screening and Decolonization |
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1035 | (1) |
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Recommended Antimicrobial Agents |
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1035 | (9) |
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Prevention of Bacterial Endocarditis |
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1044 | (2) |
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Prevention of Neonatal Ophthalmia |
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1046 | (5) |
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1046 | (1) |
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1047 | (1) |
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1047 | (1) |
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Other Nongonococcal, Nonchlamydial Ophthalmia |
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1048 | (1) |
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Administration of Neonatal Ophthalmic Prophylaxis |
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1049 | |
Appendices |
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1051 | (6) |
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II Codes for Commonly Administered Pediatric Vaccines/Toxoids and Immune Globulins |
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1057 | (1) |
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1058 | (11) |
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IV Nationally Notifiable Infectious Diseases in the United States |
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1069 | (2) |
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V Guide to Contraindications and Precautions to Immunizations |
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1071 | (11) |
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VI Prevention of Disease From Contaminated Food Products |
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1082 | (4) |
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VII Clinical Syndromes Associated With Foodborne Diseases |
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1086 | (7) |
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VIII Diseases Transmitted by Animals (Zoonoses) |
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1093 | |