In a field this highly charged there are bound to be open questions and avenues of new research, and the contributors of these articles give readers not only the most up-to-date advances but ideas for further studies building upon their own. They concentrate on the interrelationship of RNA and DNA editing with other chemical and biological processes, working on the diversification of the proteome through RNA and DNA editing (including diversification of the exon code, antibody gene diversification, interactions in RNA editing processes, and the machinery of RNA editing in plant organelles), functional coordination of RNA editing with other cellular mechanisms (including transfer DNA editing enzymes, A-to-1 editing as a co-transcritional RNA processing event, ribonucleoprotein catalysts, spliceosomal RNA modifications, gene silencing, APOBEC-1 and APOBEC-1 complementation factor, and antiviral functions of APOBEC-3 cytidine deaminases) predictive structures (including editing of repeats) and structural approaches (including the features of the ADAR family of enzymes and their substrates). Annotation ©2008 Book News, Inc., Portland, OR (booknews.com)
RNA and DNA Editing assembles a team of leading experts who present the latest discoveries in the field alongside the latest models and methodology. In addition, the authors set forth the many open questions and suggest routes for further investigation. Overall, the book serves as a practical guide for professionals in the field who need to understand the interrelationship of RNA and DNA editing with other chemical and biological processes.