ROSSIS PRINCIPLES OF TRANSFUSION MEDICINE Transfusion Medicine impacts patients with hematologic, oncologic, and surgical conditions as well as all areas of critical care medicine and multiple areas of chronic care. This book aims to be the single best source for information related to any aspect or application of Transfusion Medicine.
Contributors for the sixth edition have once again been drawn from various scientific, medical, and surgical disciplines. Thus, this book ranges from encouraging and managing donors, to collecting and preserving the blood, to matching it to the appropriate recipient, all the way to its clinical uses. It also extends these concepts to implantable tissue and regenerative medicine. Other sample topics covered within the work include:
- Contemporary issues in donation and transfusion: patient blood management, clinical and technical aspects of blood administration, and donor and patient Hemovigilance
- Blood components and derivatives: red blood cell metabolism, preservation and oxygen delivery, blood groups, and composition of plasma
- Apheresis, transplantation, and new therapies: hematopoietic growth factors, therapeutic phlebotomy and cellular apheresis, HLA antigens, alleles, and antibodies
- How Transfusion Medicine has been affected by the coronavirus pandemic, the role of pathogen reduction and other modern trends
This book serves as a complete and comprehensive resource on Transfusion Medicine for clinicians who prescribe blood, students who expect to enter clinical practice, and for the scientists, physicians, nurses, technologists, and others who assure the quality and availability of blood services.
Contributors
Preface
List of abbreviations
Section I: Transfusion medicine from ancient times to the current pandemic
Chapter
1. Transfusion in the new millennium Ennio C. Rossi and Toby L.
Simon
Chapter
2. Disaster and the blood community (including COVID-19)-Ruth
Sylvester and Louis M. Katz
Chapter
3. Responding to the Regulatory Challenges during Emergencies and
Epidemics- Peter Mark
Section II: Blood donation
Chapter 4 Recruitment and screening of donors and the collection of
bloodSusan Rossmann, Mary Townsend and Toby L. Simon
Chapter 5 Blood donor testingJed B. Gorlin and Nancy Van Buren
Chapter 6 Acute adverse reactions after blood donation Anne F. Eder
Chapter 7 Chronic effects of blood and plasma donationBryan Spencer and T.
Simon
Chapter 8 Global perspective: ensuring blood and blood product safety and
availability through regulation and certification-Eva D. Quinley
Section III: Blood groups and pretransfusion testing
Chapter 9 Carbohydrate blood groups- Laura Cooling
Chapter 10 Rh and LW blood group antigens- Connie M. Westhoff, Don L.
Siegel, and Aline Floch
Chapter 11 Other protein blood groups- Jill Storry and Jennifer Ricci
Hagman
Chapter 12 Molecular and routine compatibility testingConnie Westhoff
Section IV: Blood components
Part A. Red cells
Chapter 13 Red blood cell production and kineticsMark J. Koury and Lionel
Blanc
Chapter 14 Red cell metabolism, preservation and oxygen deliveryJohn Hess
and Angelo DAlessandro
Part B: Platelets
Chapter 15 Platelet production and kinetics- Christopher A. Tormey, Henry M.
Rinder, and Thomas C. Binns
Chapter 16 Platelet immunology and alloimmunization- Cheryl L. Maier and
Seema R. Patel and H. Clifford Sullivan
Chapter 17 Preparation, preservation, and storage of platelet concentrates-
Moritz Stolla and Valery J. Li and Johnathan P. Mack
Part C: White cells
Chapter 18 Neutrophil production and kinetics: neutropenia and neutrophilia-
Lawrence Rice and Eric Salazar
Chapter 19 Granulocyte collection and transfusion- Jeffrey McCullough,
Corrinne Goldberg and Jenny Petkova
Part D: Plasma
Chapter 20 Composition of plasma Peter Hellstern
Chapter 21 Plasma and cryoprecipitate for transfusion including SD plasma-
Simon Stanworth and Toruma Apelseth
Chapter 22 The purification of plasma proteins for therapeutic use- Nathan
Brinkman, Karl McCann, and Barry Gooch
Chapter 23 Immunoglobulins Products- Melvin Berger
Section V: Apheresis
Chapter 24 Basic principles of apheresis and the collection of blood
components by apheresis- Jeffrey L. Winters and Edwin A. Burgstaler
Chapter 25 Therapeutic apheresis: Plasma processing Patricia A.R. Brunker
and Monica B. Pagano
Chapter 26 Therapeutic phlebotomy and specialized hemapheresis- Patricia
Brunker and Jeffey Bailey
Section VI: Blood transfusion
Chapter 27 Patient blood management- Darrell J. Triulzi and Jansen N.
Seheult and
Mark H. Yazer and Jonathan H. Waters
Chapter 28 Clinical and technical aspects of blood administration Edward
S. Lee, Debra L. Mraz, and Edward L. Snyder
Chapter 29 Anemia and RBC transfusion- Jeff Carson
Chapter 30 Sickle cell disease, thalassemia, and hereditary hemolytic
anemias-Ross M. Fasano, Emily Riehm Meier and Satheesh Chonat
Chapter 31 Autoimmune hemolytic anemias and paroxysmal nocturnal
hemoglobinuria-Christopher A. Tormey and Alexa J. Siddon
Chapter 32 Hemolytic disease of the fetus and newborn- Megan Delaney, Wen
Lun, Jennifer Webb
Chapter 33 Obstetric transfusion practice- Roback
Chapter 34 Transfusion in Infants and Children-Jeanne E. Hendrickson and
Cassandra D. Josephson
Chapter 35 Thrombocytopenia and platelet transfusion-Michael F. Murphy, Lise
J Estcourt and Simon J. Stanworth
Chapter 36 Immune mediated Thombocytopenia- Theodore Warkentin, Donald
Arnold, Ishac Nazi, and James W. Smith
Chapter 37 Coagulation Concentrates for Inherited Bleeding DisordersRobert
F. Sidonio and Gary M. Woods
Chapter 38 Coagulation factor concentrates and pharmacologic therapies for
acquired bleeding disorders- Ravi Sarode and Natalie Bavli
Chapter 39 Perioperative transfusion practice- James R. Stubbs, Allan
Klompas, and Leanne Thalji
Chapter 40 Transfusion therapy in the care of trauma and burn patients- John
R. Hess, Eileen M. Bulger, Benjamin Huebner, and Samuel Mandell
Chapter 41 Transfusion support for the oncology patient- Kristin M.
Stendahl, Wade L. Schulz, Edward L. Snyder
Chapter 42 Pathogen reduction of blood components- Snyder and
McCullough
Section VII: Adverse sequelae of transfusion
Chapter 43 Hemovigilance: weighing transfusion risks and benefits- Scott
Kopesell
Chapter 44 Transfusion transmitted virus infections-Erhard Seifried
Chapter 45 Transfusion transmission of parasites and prions - Bryan Spencer
and Paula Saa
Chapter 46 Bacterial Contamination of Blood Components- Evan M. Bloch,
Richard J. Benjamin and Sandra Ramirez
Chapter 47 Hemolytic transfusion reactions- Celina Montemayor Garcia and
Sandhya R. Panch
Chapter 48 Febrile, allergic, and nonimmune transfusion reactions- Emmanuel
A. Fadeyi and Gregory J. Pomper
Chapter 49 Transfusion-related lung injury- Ulrich Sachs and Johnathan P.
Wallis
Chapter 50 Transfusion-associated graft-versus-host disease- Eric A. Gehrie
and Courtney E. Lawrence
Chapter 51 Transfusion-associated iron overload- Sujit Sheth
Section VIII: Cellular and tissue transplant technologies
Chapter 52 Hematopoetic growth factors and Cytokines-David Kuter
Chapter 53 Hematopoetic stems cells and transplantation- Garrett S. Booth
Chapter 54 HLA antigens, alleles, and antibodiesHarold Clifford Sullivan,
Robert A. Bray, Howard M. Gebel and Scott M. Krummey
Chapter 55 Car-T cells and other cellular immunotherapies- Don Siegel and
Andrew Fesnak
Chapter 56 Gene therapy applications to transfusion medicine-Diane S.
Krause, Seena Tabibi, Emanuela M. Bruscia and Eric A. Gehrie
Chapter 57 Tissue engineering and regenerative medicine-Julie G. Allickson
Chapter 58 Human Tissue Allografts: Following the Path from Donor to
Recipient - Matthew J. Kuehnert and Cassandra D. Josephson
Index
Toby L. Simon, MD is Senior Medical Director for Plasma and Plasma Safety with CSL Plasma and in Research and Development for the parent company CSL Behring, He is past-president of AABB and Americas Blood Centers. He has been on the faculty of University of New Mexico School of Medicine (currently clinical faculty), Medical Director of TriCore Reference Laboratories and industry representative to the FDA Blood Products Advisory Committee.
Eric A. Gehrie, MD is a clinical pathologist who specializes in blood banking/transfusion medicine. He is currently the Executive Physician Director over Direct Patient Care and Emerging Cell and Gene Therapy Solutions at the American Red Cross. He has previously been on the faculty of both Yale and Johns Hopkins University Schools of Medicine. He is a member of the editorial board of Transfusion.
Jeffrey McCullough, MD is Professor Emeritus at the University of Minnesota Medical School with experience in both hospital transfusion services and blood centers. He was the editor of Transfusion for 15 years and the founding president of the US National Marrow Donor Program. He is currently an international advisor in transfusion medicine. He is past-president of the American Board of Pathology.
John D. Roback, MD, PhD is a Professor in the Department of Pathology and Laboratory Medicine at Emory University. His appointments include Medical Director of Emory Medical Laboratories, Emory/Childrens Laboratory for Innovative Assay Development, and the Center for Transfusion and Cellular Therapies. He is also Executive Vice-Chair of Clinical Operations. He is a former editor of the AABB Technical Manual.
Edward L. Snyder, MD, FACP is Professor of Laboratory Medicine and Attending Physician in the Transfusion and Tissue Services at Yale Medical School/Yale New Haven Hospital. He is also the blood bank director at Bridgeport Hospital. He is past chair of the BeTheMatch Board of Directors and is a past-president of AABB. He is an associate editor of Transfusion and past-recipient of Emily Cooley, Morton Grove-Rasmussen and presidential awards from AABB.
