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El. knyga: Secret of Life: Rosalind Franklin, James Watson, Francis Crick, and the Discovery of DNA's Double Helix

4.15/5 (756 ratings by Goodreads)
(University of Michigan)
  • Formatas: 576 pages
  • Išleidimo metai: 21-Sep-2021
  • Leidėjas: WW Norton & Co
  • Kalba: eng
  • ISBN-13: 9781324002246
  • Formatas: 576 pages
  • Išleidimo metai: 21-Sep-2021
  • Leidėjas: WW Norton & Co
  • Kalba: eng
  • ISBN-13: 9781324002246

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James Watson and Francis Crick’s 1953 discovery of the double helix structure of DNA is the foundation of virtually every advance in our modern understanding of genetics and molecular biology. But how did Watson and Crick do it—and why were they the ones who succeeded In truth, the discovery of DNA’s structure is the story of five towering minds in pursuit of the advancement of science, and for almost all of them, the prospect of fame and immortality: Watson, Crick, Rosalind Franklin, Maurice Wilkins, and Linus Pauling. Each was fascinating and brilliant, with strong personalities that often clashed. Howard Markel skillfully re-creates the intense intellectual journey, and fraught personal relationships, that ultimately led to a spectacular breakthrough. But it is Rosalind Franklin—fiercely determined, relentless, and an outsider at Cambridge and the University of London in the 1950s, as the lone Jewish woman among young male scientists—who becomes a focal point for Markel.The Secret of LifeThe Secret of Life

Recenzijos

"A cinematic account of toxic masculinity among 1950s DNA researchers [ Rosalind Franklin] probably would have hated being the heroine of a movie, but were fortunate to have books such as this to put her back in the picture." -- Katy Guest - The Guardian "Howard Markels wonderfully-written book, The Secret of Life, explores the story of genetics up to the revolutionary mid-20th century decoding of the structure of DNA. And it does so in such brilliant detail that the result iseven for those who might think they know this storya tale that proves fresh, provocative, startlingly insightful, and addictively fun to read." -- Deborah Blum, Pulitzer Prizewinning author of The Poison Squad: One Chemists Single-Minded Crusade for Food Safety at the Turn of the Twentieth Century "The discovery of DNA is one of historys light switch moments, when the world of scienceindeed, humanitychanged forever. Though much has been written on the subject, nothing remotely compares to Howard Markels magisterial account. Elegantly written, packed with fresh insights gleaned from a wealth of original sources, The Secret of Life takes us into the minds and laboratories of the leading players, highlighting their brilliance, their ambitions, and their sometimes questionable ethical behavior. This book is the merging of a seminal subject and superb authorone of the leading medical historians of our era. The result is truly remarkable." -- David Oshinsky, Professor of History and Medicine, NYU, and Pulitzer Prizewinning author of Polio: An American Story "Howard Markels brilliant book examining the discovery of DNA is a must read for biologists and historians. But this is also a book for every reader; it brings to life the discovery of life itself. From Watson, Crick, and Franklin, to the dozens of char" -- Siddhartha Mukherjee, Pulitzer Prizewinning author of The Emperor of All Maladies and The Gene

PART I PROLOGUE
1 Opening Credits
3(11)
2 The Monk and the Biochemist
14(8)
3 Before the Double Helix
22(13)
PART II THE PLAYERS' CLUB
4 Take Me to the Cavendish Laboratory
35(14)
5 The Third Man
49(14)
6 Like Touching the Fronds of a Sea Anemone
63(27)
7 There Was No One Like Linus in All the World
90(15)
8 The Quiz Kid
105(22)
PART III TICKTOCK, 1951
9 Vide Napule e po' muore
127(16)
10 From Ann Arbor to Cambridge
143(12)
11 An American in Cambridge
155(11)
12 The King's War
166(18)
13 The Lecture
184(18)
14 The Dreaming Spires of Oxford
202(13)
15 Mr. Crick and Dr. Watson Build Their Dream Model
215(22)
PART IV MORATORIUM, 1952
16 Dr. Pauling's Predicament
237(9)
17 Chargaff's Rules
246(10)
18 Paris and Royaumont
256(9)
19 A Haphazard Summer
265(14)
PART V THE HOME STRETCH, NOVEMBER 1952-APRIL 1953
20 Linus Sings
279(8)
21 A Stomach Ache in Clare College
287(8)
22 Peter and the Wolf
295(7)
23 Photograph No. 51
302(15)
24 The Mornings After
317(13)
25 The MRC Report
330(10)
26 Base Pairs
340(13)
27 It's So Beautiful
353(11)
28 Defeat
364(13)
29 It Has Not Escaped Our Notice
377(28)
PART VI THE NOBEL PRIZE
30 Stockholm
405(12)
31 Closing Credits
417(12)
Acknowledgments 429(4)
Notes 433(104)
Illustration Credits 537(4)
Index 541
Howard Markel, MD, PhD, has practiced pediatrics and taught medical history at Johns Hopkins and University of Michigan. An award-winning author of The Secret of Life, National Academy of Medicine member, and Guggenheim fellow, he lives in New York.