The third edition is a comprehensive and updated overview of positive and negative effects of UV-exposure, with a focus on Vitamin D and skin cancer. Researchers, oncologists,and students will be provided with the most significant and timely information related to topics such as the epidemiology of skin cancer, the immune system and skin cancer, ultraviolet damage, DNA repair and Vitamin D in Nonmelanoma skin cancer and malignant melanoma. There have been a number of new, scientific findings in this fast moving field that necessitated a thoroughly updated and revised edition including new Vitamin D metabolites and skin cancer, new findings on the beneficial effects of UV and solar UV and skin cancer, adverse effects of sun protection and suncreens, sun exposure and mortality, and more. The book will summarize essential, up-to-date information for every clinician or scientist interested in how to balance the positive and negative effects of UV-exposure to minimize the risks of developing vitamin D deficiency and skin cancer.
Section I: Introduction .- Lessons learned from paleolithic models and
evolution for human health: a snap shot on beneficial effects and risks of
solar radiation.- Section II: UV-induced cutaneous synthesis of vitamin D and
the physiologic consequences (I).- Sunlight, UV-radiation, vitamin D and skin
cancer: how much sunlight do we need?.- Section III: Solar radiation, Vitamin
D and human health.- Vitamin D status and cancer incidence and
mortality.- Vitamin D receptors polymorphisms and cancer.- On the
relationship between sun exposure and all-cause mortality.- Lindqvist PG
(2020) Women with greater sun exposure habits seem to be healthier and to
live longer. Are these results in contrast to other research? No.- Section
IV: Epidemiology of skin cancer.- Epidemiology of skin cancer and UV
radiation update 2019.- Solar UV exposure and mortality from skin tumors:
an update.- Solarium Use and Risk for Malignant Melanoma: many open
questions,not the time to close the debate.- Section V: Photocarcinogenesis
of skin cancer.- Molecular biology of basal and squamous cell
carcinomas.- Human papillomaviruses and skin cancer.- The immune system and
pathogenesis of melanoma and nonnmelanoma skin cancer.- Section VI: The
relevance of the vitamin D endocrine system for skin cancer.- Protection from
ultraviolet damage and photocarcinogenesis by vitamin D compounds.- The role
of classical and novel forms of vitamin D in the pathogenesis and
progression of non-melanoma skin cancers.- The Vitamin D Receptor as tumor
suppressor in skin.- Cancer prevention in skin and other tissues via
cross-talk between vitamin D- and p53- signalling.- Section VII: Prevention
and Management of Skin Cancer.- Sunscreens in the United States: Current
Status and Future Outlook.- A handful of sunscreen for whole body
application.- Sunlight, vitamin D and Xeroderma pigmentosum.- Update: Solar
UV-radiation, vitamin D and skin cancer surveillance in organ transplant
recipients (OTRs).- Section VIII: UV-induced cutaneous synthesis of vitamin D
and the physiologic consequences II. promise and outlook .- Ultraviolet
exposure scenarios: balancing risks of erythema and cutaneous vitamin D
synthesis.- The Paleolithic nutrition model in relation to ultraviolet light
and vitamin D.- Index.
JÖRG REICHRATH is Professor for Dermatology and Deputy Director of the Clinic for Dermatology, Allergology and Venerology at the Saarland University Hospital in Homburg, Germany. Reichrath has received his academic degrees (Dr. med) from the Saarland University, Germany. His research interests include photobiology, dermato-endocrinology and dermato-oncology. He is a member of numerous national and international scientific organizations, including the German Dermatological Society (DDG), the Deutsche Krebsgesellschaft (DKG), the German Dermatologic Cooperative Oncology Group (DeCOG), and the European Society of Dermatological Research (ESDR). He has been awarded numerous prices including the Arnold-Rikli-price.
Daugiau apie elektronines knygas