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Superbugs: Deadly Microbes and the Extraordinary Race for a Cure: A Tale of Human Ingenuity [Minkštas viršelis]

3.96/5 (134 ratings by Goodreads)
  • Formatas: Paperback / softback, 304 pages, aukštis x plotis x storis: 228x151x20 mm, weight: 369 g, 304
  • Išleidimo metai: 09-Jun-2020
  • Leidėjas: Avery Publishing Group Inc.,U.S.
  • ISBN-10: 0735217513
  • ISBN-13: 9780735217515
Kitos knygos pagal šią temą:
  • Formatas: Paperback / softback, 304 pages, aukštis x plotis x storis: 228x151x20 mm, weight: 369 g, 304
  • Išleidimo metai: 09-Jun-2020
  • Leidėjas: Avery Publishing Group Inc.,U.S.
  • ISBN-10: 0735217513
  • ISBN-13: 9780735217515
Kitos knygos pagal šią temą:
International Bestseller

"An amazing, informative book that changes our perspective on medicine, microbes and our future."
--Siddhartha Mukherjee, MD, New York Times bestselling author of The Emperor of All Maladies

A New York Times bestselling author shares this exhilarating story of cutting-edge science and the race against the clock to find new treatments in the fight against the antibiotic-resistant bacteria known as superbugs.


Physician, researcher, and ethics professor Matt McCarthy is on the front lines of a groundbreaking clinical trial testing a new antibiotic to fight lethal superbugs, bacteria that have built up resistance to the life-saving drugs in our rapidly dwindling arsenal. This trial serves as the backdrop for the compulsively readable Superbugs, and the results will impact nothing less than the future of humanity.

Dr. McCarthy explores the history of bacteria and antibiotics, from Alexander Fleming's discovery of penicillin, to obscure sources of innovative new medicines (often found in soil samples), to the cutting-edge DNA manipulation known as CRISPR, bringing to light how we arrived at this juncture of both incredible breakthrough and extreme vulnerability. We also meet the patients whose lives are hanging in the balance, from Remy, a teenager with a dangerous and rare infection, to Donny, a retired New York City firefighter with a compromised immune system, and many more.

The proverbial ticking clock will keep readers on the edge of their seats. Can Dr. McCarthy save the lives of his patients infected with the deadly bacteria, who have otherwise lost all hope?
Author's Note xi
Prologue 1(8)
PART 1 A CHANCE OBSERVATION
Chapter 1 The Fog of War
9(8)
Chapter 2 A Golden Era
17(12)
PART 2 FIRST PRINCIPLES
Chapter 3 The Lucky Grenadier
29(10)
Chapter 4 Embedded
39(6)
Chapter 5 Safeguards
45(5)
Chapter 6 Variables
50(4)
Chapter 7 Deferment
54(6)
Chapter 8 Oversight
60(11)
Chapter 9 Backwater
71(14)
PART 3 THE VOLUNTEERS
Chapter 10 Ruth
85(8)
Chapter 11 George
93(5)
Chapter 12 Mississippi Mud
98(6)
Chapter 13 Soren
104(6)
Chapter 14 Duty
110(5)
Chapter 15 Remy
115(4)
Chapter 16 AQuietRevolution
119(7)
Chapter 17 Decision Points
126(6)
Chapter 18 Piper
132(4)
Chapter 19 Garden State
136(5)
Chapter 20 Trojan Horses
141(6)
PART 4 BENEATH THE SURFACE
Chapter 21 The Rockefellers
147(4)
Chapter 22 Lysin
151(5)
Chapter 23 Breakthrough
156(6)
Chapter 24 Anthrax
162(5)
Chapter 25 Delivery
167(6)
PART 5 TOWARD A CURE
Chapter 26 Meghan
173(7)
Chapter 27 Mantra
180(7)
Chapter 28 Obstacles
187(4)
Chapter 29 First
191(4)
Chapter 30 Alicia
195(4)
Chapter 31 Persuasion
199(5)
Chapter 32 The Rollout
204(6)
Chapter 33 Investments
210(5)
Chapter 34 Into the Haystack
215(3)
Chapter 35 AngryBirds
218(6)
Chapter 36 Macaulay
224(3)
Chapter 37 Searching
227(4)
Chapter 38 Anna
231(5)
Chapter 39 Reversals and Rewards
236(4)
Chapter 40 Help Wanted
240(11)
Epilogue 251(8)
Acknowledgments 259(1)
A Note on Sources 260(1)
Notes 261(18)
Index 279