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Targeted Radiopharmaceuticals and Imaging: Development Challenges and Opportunities [Kietas viršelis]

Edited by (Global Peptide Science Institute (GPSi), USA), Edited by (Tata Memorial Centre, India)
  • Formatas: Hardback, 502 pages, aukštis x plotis x storis: 234x156x29 mm, weight: 908 g
  • Serija: Drug Development and Pharmaceutical Science Volume 5
  • Išleidimo metai: 04-Jun-2025
  • Leidėjas: Royal Society of Chemistry
  • ISBN-10: 1837673276
  • ISBN-13: 9781837673278
Kitos knygos pagal šią temą:
  • Formatas: Hardback, 502 pages, aukštis x plotis x storis: 234x156x29 mm, weight: 908 g
  • Serija: Drug Development and Pharmaceutical Science Volume 5
  • Išleidimo metai: 04-Jun-2025
  • Leidėjas: Royal Society of Chemistry
  • ISBN-10: 1837673276
  • ISBN-13: 9781837673278
Kitos knygos pagal šią temą:

Bringing a cohesive picture on different radiopharmaceutical therapies for cancer treatment, this book will address the challenges in developing and commercialising radiopharmaceuticals.



Targeted radiopharmaceutical therapy (RPT) is emerging as an innovative approach for treating a wide range of cancers.

Almost all radionuclides used in RPT emit photons that can be imaged, enabling non-invasive visualization of the therapeutic agent's biodistribution. The remarkable potential of radiopharmaceutical therapy is now being recognized with recent FDA approval of several RPT drugs and a significant number of drug candidates in clinical development.

This book offers a comprehensive perspective on the different technologies and addresses the critical challenges in developing and commercializing radiopharmaceuticals. It covers various topics, from clinical applications to specific radiopharmaceutical biodistribution, dosimetry, and novel targets in oncology. The chapters provide a cohesive picture of the advances in SPECT/CT and PET/CT imaging, clinical trends in targeted therapies utilizing radioisotopes for cancer imaging, and clinical applications of radiotracers within oncology areas. It also delves into the manufacturing technologies and regulatory and supply logistics required to support the development of the next wave of targeted alpha therapies.

This resource is ideal for postgraduates and researchers in drug discovery and development in radionuclide therapy and imaging in cancer, as well as medical professionals engaged in nuclear medicine and radiology.

Targeted Radiopharmaceuticals: Clinical Development and Commercial
Landscape

Advances in Targeted Radiopharmaceuticals: Challenges and Opportunities

Alpha-particle Emitting Radiopharmaceuticals in Targeted Therapy and
Diagnostics: Challenges and Opportunities

Chelator Design and Radiolabeling Chemistry of Radiometals

Dosimetry Methods for Radiopharmaceuticals

Glypican-3 (GPC3) Targeted Radiopharmaceuticals for Treatment of Liver
Cancer

Identifying New Molecular Modalities for Radionuclide Therapy Using
Macrocyclic Peptide Mimetics

Peptides and Small Radiopharmaceuticals for Molecular Targeting

Antibody Based Radiopharmaceuticals in Clinical Development

Prostate-specific Membrane Antigen Targeted Prostate Imaging and Therapy

Radiotracers for Imaging of Breast Cancer and Targeted Radionuclide Therapy

Neuroendocrine Tumors: Radiopharmaceuticals for Imaging and Therapy

Radiopharmaceuticals for Imaging and Therapy in Neurology

Thyroid Imaging and Radionuclide Therapy

Radiopharmaceuticals for Skeletal Imaging and Therapy

Radiopharmaceuticals in Dermatologic Imaging and Therapy

Targeted Radiopharmaceuticals for Infection Imaging

Manufacturing Challenges and Radiopharmaceutical Application of 18F-labeled
Heterocycles for PET Imaging

Quality Considerations in Radiopharmaceuticals