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Textbook of Hyperbaric Medicine 6th ed. 2017 [Kietas viršelis]

  • Formatas: Hardback, 640 pages, aukštis x plotis: 279x210 mm, 83 Illustrations, color; 88 Illustrations, black and white; XLVIII, 640 p. 171 illus., 83 illus. in color., 1 Hardback
  • Išleidimo metai: 16-Dec-2016
  • Leidėjas: Springer International Publishing AG
  • ISBN-10: 3319471384
  • ISBN-13: 9783319471389
Kitos knygos pagal šią temą:
  • Formatas: Hardback, 640 pages, aukštis x plotis: 279x210 mm, 83 Illustrations, color; 88 Illustrations, black and white; XLVIII, 640 p. 171 illus., 83 illus. in color., 1 Hardback
  • Išleidimo metai: 16-Dec-2016
  • Leidėjas: Springer International Publishing AG
  • ISBN-10: 3319471384
  • ISBN-13: 9783319471389
Kitos knygos pagal šią temą:
This comprehensive volume captures the latest scientific evidence, technological advances, treatments and impact of biotechnology in hyperbaric oxygen therapy. Divided into three distinct sections, the book begins with basic aspects that include history, equipment, safety and diagnostic approaches; this is followed by clinical applications for hyperbaric oxygen therapy in various modalities; the last section provides an overview of hyperbaric medicine as a specialty with best practices from around the world. Integration of multidisciplinary approaches to complex disorders are also covered.Updated and significantly expanded from previous editions, Textbook of Hyperbaric Medicine, 6th Edition will continue to be the definitive guide to this burgeoning field for students, trainees, physicians and specialists.

Part I. Basic Aspects.- Chapter 1. The History of Hyperbaric Medicine.- Chapter 2. Physical, Physiological, and Biochemical Aspects of Hyperbaric Oxygenation.- Chapter 3. Effects of Diving and High Pressure on the Human Body.- Chapter 4. Physical Exercise under Hyperbaric Conditions.- Chapter 5. Hypoxia.- Chapter 6. Oxygen Toxicity.- Chapter 7. Hyperbaric Chambers: Equipment, Technique, and Safety.- Chapter 8. Indications, Contraindications, and Complications of HBO Therapy.- Chapter 9. Drug Interactions with Hyperbaric Oxygenation.- Chapter 10. Neurophysiologic SPECT Brain Function Imaging and Hyperbaric Oxygen Therapy.- Part II. Clinical Applications.- Chapter 11. Decompression Sickness.- Chapter 12. Cerebral Air Embolism.- Chapter 13. Carbon Monoxide and Other Tissue Poisons.- Chapter 14. HBO Therapy in Infections.- Chapter 15. Hyperbaric Oxygen Therapy and Chronic Lyme Disease: The Controversy and the Evidence.- Chapter 16. HBO Therapy in Wound Healing, Plastic Surgery, and De

rmatology.- Chapter 17. HBO Therapy in the Management of Radionecrosis.- Chapter 18. The Use of HBO in Treating Neurological Disorders.- Chapter 19. Role of Hyperbaric Oxygenation in the Management of Stroke.- Chapter 20. HBO Therapy in Global Cerebral Ischemia/Anoxia and Coma.- Chapter 21. HBO Therapy in Neurosurgery.- Chapter 22. Oxygen Treatment for Multiple Sclerosis Patients.- Chapter 23. HBO in the Management of Cerebral Palsy.- Chapter 24. HBO Therapy in Miscellaneous Neurological Disorders.- Chapter 25. HBO Therapy in Cardiovascular Diseases.- Chapter 26. HBO Therapy in Hematology and Immunology.- Chapter 27. HBO Therapy in Gastroenterology.- Chapter 28. HBO and Endocrinology.- Chapter 29. HBO and Pulmonary Disorders.- Chapter 30. Hyperbaric Oxygenation in Traumatology and Orthopedics.- Chapter 31. HBO Therapy in Otolaryngology.- Chapter 32. HBO Therapy and Ophthalmology.- Chapter 33.Hyperbaric Oxygenation in Obstetrics and Gynecology.- Chapter 34. Use of Hyperbaric Oxygen

ation (HBO2) in Neonatal Patients.- Chapter 35. Hyperbaric Oxygenation in Geriatrics.- Chapter 36. HBO as an Adjuvant in Rehabilitation and Sports Medicine.- Chapter 37. Nursing and Hyperbaric Medicine.- Chapter 38. Role of HBO in Enhancing Cancer Radiosensitivity.- Chapter 39. HBO Therapy and Organ Transplants.- Chapter 40. Hyperbaric Oxygen Pretreatment and Preconditioning.- Chapter 41. Anesthesia in the Hyperbaric Environment.- Chapter 42. Hyperbaric Oxygen in Resuscitation.- Chapter 43. HBO in Military Medicine.- Part III. Hyperbaric Medicine as a Specialty.- Chapter 44. Training and Practice of Hyperbaric Medicine.- Chapter 45. Research in Hyperbaric Medicine.- Chapter 46. Personalized Hyperbaric Medicine.- Chapter 47. The Future of Hyperbaric Medicine.- Chapter 48. Ethical Issues, Standards, and Quality Control in the Practice of Hyperbaric Medicine.- Chapter 49. Hyperbaric Medicine in Europe.- Chapter 50. Hyperbaric Medicine in the United States.- Chapter 51. Hyperbaric Med

icine in Latin America.

Recenzijos

This is the sixth edition of a comprehensive overview of hyperbaric medicine . Providers at any level seeking to better understand the issues and impact of hyperbaric medicine are an appropriate audience for a work featuring a panel of international experts. This remains a major survey of the field. Clearly, this is a valuable overview of a technology seeking additional applications. (David J. Dries, Doody's Book Reviews, May, 2017)

Part I Basic Aspects
1 The History of Hyperbaric Medicine
3(8)
K. K. Jain
Hyperbaric Therapy and Diving Medicine
3(1)
The Development of Hyperbaric Air Therapy
4(3)
The Development of Hyperbaric Oxygen Therapy
7(2)
References
9(2)
2 Physical, Physiological, and Biochemical Aspects of Hyperbaric Oxygenation
11(12)
K. K. Jain
Introduction
11(1)
Physical Basics
11(1)
Physiology of Oxygenation
12(1)
The Oxygen Pathway
12(1)
Ventilation Phase
12(1)
Transport Phase
12(1)
Shift of the Oxygen-Hemoglobin Dissociation Curve
13(1)
Delivery of Oxygen to the Tissues
14(1)
Oxygen Transfer at the Capillary Level
14(1)
Relation Between the Oxygen Transport and Utilization
14(1)
Oxygen Utilization in the Cell
15(1)
Effect of Blood Flow
15(1)
Effect of Oxygen-Hemoglobin Reaction on Transport of CO2
15(1)
Autoregulation of the Intracellular pO2
16(1)
Hyperbaric Oxygenation
16(1)
Theoretical Considerations
16(3)
General Effects of HBO on the Healthy Human Body
19(1)
Biochemical Effects of HBO
20(1)
Effect of HBO on Enzymes
20(1)
Effect of HBO on the Nervous System
20(1)
Effect of HBO at Molecular Level
21(1)
Conclusion
21(1)
References
21(2)
3 Effects of Diving and High Pressure on the Human Body
23(10)
K. K. Jain
Physical Effects of Pressure
23(1)
Effects of Pressure on Various Systems of the Body
23(1)
Hematological and Biochemical Effects
23(1)
Effect on Ammonia Metabolism
24(1)
Effect on Blood Cells and Platelets
24(1)
Changes in the Respiratory System and Blood Gases
24(1)
Effects on the Cardiovascular System
25(1)
Changes in the Endocrine System
25(1)
Effect on the Skeletal System
25(1)
Effects of High-Pressure Environments on the Nervous System
25(4)
Damage to the Middle Ear and Inner Ear in Diving
29(1)
Vertigo and Diving
30(1)
Taste Sensation Under High Pressure
30(1)
Effect of High Pressure on Effect of Drugs
30(1)
Conclusion
31(1)
References
31(2)
4 Physical Exercise under Hyperbaric Conditions
33(6)
K. K. Jain
Introduction
33(1)
Exercise and Hypoxia
34(1)
Exercise in Hyperbaric Environments
34(1)
Exercise Under Hyperoxia
35(1)
Physical Exercise Under Hyperbaric Conditions
35(1)
General Effects
35(1)
Effect on Lactate Production and Clearance
36(1)
Effect of Exercise on Ammonia Metabolism
37(1)
Effect of HBO on Antioxidant Enzymes in Skeletal Muscle
37(1)
Effect of HBO on Blood Flow to the Muscles During Exercise
37(1)
Physical Exercise in Relation to Toxic Effects of HBO
38(1)
Conclusion
38(1)
References
38(1)
5 Hypoxia
39(10)
K. K. Jain
Introduction
39(1)
Pathophysiology of Hypoxia
39(1)
Hypoxia-Inducible Factor
40(1)
Hypoxia and Heat Shock Proteins
40(1)
Effect of Hypoxia on Cellular Metabolism
40(1)
Impact of Hypoxia on Various Body Systems
41(1)
Respiratory Function
41(1)
Cardiovascular System
41(1)
General Metabolic Effects
41(1)
Effects of Hypoxia on the Brain
42(4)
Role of HBO in the Treatment of Hypoxic States
46(1)
The Role of Nitric Oxide Synthase in the Effect of HBO in Hypoxia
47(1)
Possible Dangers of HBO in Hypoxic States
47(1)
References
48(1)
6 Oxygen Toxicity
49(12)
K. K. Jain
Introduction
49(1)
Pathophysiology of Oxygen Toxicity
50(1)
Free Radical Mechanisms
50(1)
Pathology of Oxygen Toxicity
50(2)
Pulmonary Oxygen Toxicity
52(1)
Normobaric vs. Hyperbaric Oxygen in Induction of Pulmonary Oxygen Toxicity
53(1)
Oxygen-Induced Retinopathy
53(1)
Factors That Enhance Oxygen Toxicity
53(1)
Central Nervous System Oxygen Toxicity
54(2)
Ammonia and Amino Acids
56(1)
Biomarkers of Oxygen Neurotoxicity
56(1)
Neuropathology of Oxygen Toxicity
56(1)
Manifestations of CNS Oxygen Toxicity
57(1)
Clinical Monitoring for Oxygen Toxicity
57(1)
Protection Against Oxygen Toxicity
57(2)
Extension of Oxygen Tolerance
59(1)
Conclusion and Directions for Future Research
59(1)
References
60(1)
7 Hyperbaric Chambers: Equipment, Technique, and Safety
61(18)
K. K. Jain
Introduction
61(1)
Monoplace Chambers
61(1)
Multiplace Chambers
62(2)
Multiplace Chambers for the Critical Care Department
64(1)
Surgery in the Multiplace Chamber
65(1)
Mobile Multiplace Hyperbaric Chambers
65(1)
Hyperbaric Chambers for Diving Medicine
66(1)
Hyperbaric Chambers for Animal Research
66(2)
Selection of a Hyperbaric Chamber
68(1)
Technique of Hyperbaric Oxygenation
68(2)
Ancillary Equipment
70(1)
Oxygen Masks and Hoods
70(1)
Respirators and Ventilators
70(1)
Diagnostic Equipment
71(1)
ECG and EEG
71(1)
Transcutaneous Oxygen Tension
71(1)
Glucose-Monitoring Devices
71(1)
Use of Miscellaneous Medical Devices in the Hyperbaric Chamber
72(1)
Cardiopulmonary Resuscitation
72(1)
Use of Defibrillators in Hyperbaric Chambers
72(1)
Pleural Suction Drainage
72(1)
Endotracheal Tubes
72(1)
Care of Tracheotomy
72(1)
Continuous Bladder Irrigation and HBO
72(1)
Transdermal Patches for Drug Delivery and Hyperbaric Chamber
73(1)
Implanted Devices in Patients
73(1)
Monitoring of Patients in the Hyperbaric Chamber
73(1)
Safety in the Hyperbaric Chamber
74(1)
Operational Safety
74(1)
Masks and Breathing Control System
74(1)
Fire Safety in the Chamber
74(2)
Use of Portable Hyperbaric Chambers in Patient's Rooms
76(1)
Regulatory Issues Relevant to Hyperbaric Medicine
76(1)
Staffing of Hyperbaric Facilities
77(1)
Conclusion
77(1)
References
77(2)
8 Indications, Contraindications, and Complications of HBO Therapy
79(6)
K. K. Jain
Indications
79(1)
Contraindications
79(2)
Complications of Hyperbaric Oxygenation
81(1)
Middle Ear Barotrauma
81(1)
Ophthalmological Complications of HBO
82(1)
Pulmonary Complications of HBO
82(1)
Oxygen Seizures
82(1)
Decompression Sickness
83(1)
Genetic Effects
83(1)
Claustrophobia
83(1)
Anxiety Reactions
83(1)
Coincidental Medical Events in the Hyperbaric Chamber
84(1)
Precautions in Selection of Patients for HBO Treatment
84(1)
Conclusion
84(1)
References
84(1)
9 Drug Interactions with Hyperbaric Oxygenation
85(6)
K. K. Jain
Oxygen as a Drug
85(1)
Drug--Drug Interactions
85(1)
Interactions of HBO with Other Drugs
85(1)
Interaction of HBO with Antimicrobials
86(1)
Carbapenem Antibiotics
86(1)
Aminoglycoside Antibiotics
86(1)
Sulfonamides
86(1)
Interaction of HBO with Anticancer Agents
86(1)
Interaction of HBO with Cardiovascular Drugs
86(1)
Adrenomimetic, Adrenolytic, and Ganglion-Blocking Agents
86(1)
Digitalis/Digoxin
87(1)
Antianginal Drugs
87(1)
Heparin
87(1)
Interaction of HBO with Drugs Acting on the CNS
87(1)
Anesthetics
87(1)
CNS Stimulants
87(1)
Ethanol
87(1)
Narcotic Analgesics
87(1)
Pentobarbital
87(1)
Scopolamine
87(1)
Interaction of HBO with Miscellaneous Drugs
88(1)
Practical Considerations of Drug Administration During HBO Therapy
88(1)
Drugs that Enhance Oxygen Toxicity
88(1)
Drugs that Protect Against Oxygen Toxicity
88(1)
Conclusion
89(1)
References
89(2)
10 Neurophysiologic SPECT Brain Function Imaging and Hyperbaric Oxygen Therapy
91(10)
J. Michael Uszler
Introduction
91(2)
Case Studies
93(1)
Conclusion
94(2)
Suggested Reading
96(5)
Part II Clinical Applications
11 Decompression Sickness
101(20)
Philip B. James
K. K. Jain
Introduction
101(1)
Pathophysiology
102(1)
Gas Formation
102(2)
Pulmonary Changes
104(1)
Bubble-Induced CNS Injury
104(1)
Changes in Blood
105(1)
Dysbaric Osteonecrosis
106(1)
Role of Free Radicals
106(1)
Clinical Features
106(1)
Decompression Sickness in Diving
106(1)
Altitude Decompression Sickness
107(1)
Ocular Complications of DCS
108(1)
Ultrasonic Detection of Bubbles
109(1)
Diagnosis
109(1)
Blood Examination
109(1)
Ultrasound Monitoring of Bubbles
110(1)
Bone Scanning
110(1)
X-Rays
110(1)
Retinal Angiography
110(1)
Imaging
110(1)
Electrophysiological Studies
110(1)
Neuropsychological Assessment
110(1)
Treatment
110(1)
Emergency Management and Evaluation
110(1)
Recompression and HBO Treatment
111(1)
Management of Altitude Decompression Sickness
111(3)
Management of Neurological Manifestations of Decompression Sickness
114(1)
Monoplace vs. Multiplace Chambers
115(1)
Use of Oxygen vs. Other Gas Mixtures
115(1)
Drugs
116(1)
Importance of Early Treatment
117(1)
Delayed Treatment
117(1)
Treatment of Residual Neurological Injury and SPECT Brain Imaging in Type II DCS
117(1)
Risk Factors for DCS
117(1)
Preventive Measures for DCS
118(1)
Prognosis of DCS
118(1)
Conclusion
118(1)
References
119(2)
12 Cerebral Air Embolism
121(10)
K. K. Jain
Introduction
121(1)
Causes
121(1)
Mechanisms
122(1)
Pathophysiology of Cerebral air Embolism
122(1)
Clinical Features
123(1)
Diagnosis
123(1)
Treatment
123(1)
Clinical Applications of HBO for Air Embolism
124(2)
Ancillary Treatments
126(1)
Antiplatelet Drugs
126(1)
Steroids
126(1)
Hemodilution
126(1)
Control of Seizures
126(1)
Measures to Improve Cerebral Metabolism
126(1)
Hyperbaric Treatment in Special Situations
126(1)
Cerebral Edema
126(1)
Cardiovascular Surgery
126(1)
Neurosurgery
127(1)
Pulmonary Barotrauma
127(1)
Air Embolism During Invasive Medical Procedures
127(1)
Cerebral Air Embolism During Obstetrical Procedures
127(1)
Cerebral Air Embolism in Endoscopic Retrograde Cholangiopancreatography
128(1)
Cerebral Embolism Due to Hydrogen Peroxide Poisoning
128(1)
Relapse Following Spontaneous Recovery
128(1)
Delayed Treatment
129(1)
Conclusion
129(1)
References
129(2)
13 Carbon Monoxide and Other Tissue Poisons
131(24)
K. K. Jain
Classification of Tissue Poisons
131(1)
Carbon Monoxide Poisoning
131(1)
Historical Aspects of CO Poisoning
131(1)
Biochemical and Physical Aspects of CO
131(1)
CO Body Stores
132(1)
Biochemical Effects of CO on Living Organisms
132(1)
Inhibition of the Utilization of Oxygen by CO
132(1)
Epidemiology of CO Poisoning
133(1)
Causes of CO Poisoning
134(1)
Sources of CO Poisoning
134(1)
Pathophysiology of CO Poisoning
134(1)
CO Binding to Myoglobin
134(1)
CO-Induced Hypoxia
135(1)
Effects of CO on Various Systems of the Body
135(1)
Cardiovascular System
135(1)
Hemorheological Effects of CO
136(1)
Effect of CO on Blood Lactate
136(1)
Effect of CO on the Lungs
136(1)
Exercise Capacity
136(1)
Sleep
136(1)
Effect on Pregnancy
136(1)
Musculoskeletal System
136(1)
Skin
136(1)
Gastrointestinal System
137(1)
Effects on the Peripheral Nervous System
137(1)
Effects on the Visual System
137(1)
Effect on the Auditory System
137(1)
Effect on the Central Nervous System
137(1)
Clinical Features of CO Poisoning
138(1)
Neuropsychological Sequelae of CO Poisoning
138(2)
Clinical Diagnosis of CO Poisoning
140(1)
Pitfalls in the Clinical Diagnosis of CO Poisoning
140(1)
Occult CO Poisoning
140(1)
Laboratory Diagnosis of CO Poisoning
140(1)
Brain Imaging Studies
141(1)
General Management of CO Poisoning
142(1)
Rationale for Oxygen Therapy (NBO or HBO) for CO Poisoning
143(1)
Experimental Evidence
144(1)
Clinical Use of HBO in CO Poisoning
144(1)
Clinical Trials of HBO in CO Poisoning
145(3)
HBO for CO Intoxication Secondary to Methylene Chloride Poisoning
148(1)
Treatment of CO Poisoning in Pregnancy
148(1)
Treatment of Smoke Inhalation
149(1)
Prevention and Treatment of Late Sequelae of CO Poisoning
149(1)
Controversies in the Use of HBO for CO Poisoning
149(1)
Cyanide Poisoning
150(1)
Pathophysiology
150(1)
Clinical Features of Cyanide Poisoning
150(1)
Laboratory Diagnosis
150(1)
Treatment
150(1)
Rationale for Use of HBO in Cyanide Poisoning
150(1)
Hydrogen Sulfide Poisoning
150(1)
Carbon Tetrachloride Poisoning
151(1)
Methemoglobinemias
151(1)
Treatment
151(1)
Miscellaneous Poisons
152(1)
Organophosphorus Compounds
152(1)
Conclusions: Poisoning Other Than with CO
152(1)
References
152(3)
14 HBO Therapy in Infections
155(16)
K. K. Jain
Introduction
155(1)
Host Defense Mechanisms Against Infection
155(1)
Impairment by Anoxia
155(1)
Oxygen as an Antibiotic
155(2)
HBO as an Adjuvant to Antibiotics
157(1)
HBO in the Treatment of Infections
157(1)
HBO in the Treatment of Soft Tissue Infections
158(1)
Crepitant Anaerobic Cellulitis
158(1)
Progressive Bacterial Gangrene
158(1)
Necrotizing Fasciitis
158(1)
Nonclostridial Myonecrosis
159(1)
Fournier's Gangrene
159(1)
Gas Gangrene
160(3)
Fungal Infection
163(1)
HBO in the Management of AIDS
164(1)
Miscellaneous Infections
164(1)
Osteomyelitis
165(1)
Management of Osteomyelitis
166(1)
HBO Treatment of Osteomyelitis
167(1)
Clinical Results of HBO Treatment in Osteomyelitis
168(1)
Osteomyelitis of the Jaw
168(1)
Osteomyelitis of the Sternum
168(1)
Malignant Otitis Externa
168(1)
References
169(2)
15 Hyperbaric Oxygen Therapy and Chronic Lyme Disease: The Controversy and the Evidence
171(12)
Caroline E. Fife
Kristen A. Eckert
Introduction to Lyme Disease vs. Chronic Lyme Disease: A Brief Overview
171(2)
Chronic Lyme Disease
173(1)
HBOT for Lyme Disease and CLD
174(1)
Rationale for Using HBOT
174(5)
The Need for a HBOT Medical Registry
179(1)
Conclusion
179(1)
References
180(3)
16 HBO Therapy in Wound Healing, Plastic Surgery, and Dermatology
183(24)
K. K. Jain
Introduction
183(1)
Wound Healing
184(1)
Role of Oxygen in Wound Healing
184(1)
Pathophysiology of Nonhealing Wounds
184(1)
Wound Healing Enhancement by Oxygen
185(2)
Clinical Applications
187(2)
Role of HBO in Nonhealing Wounds and Ulcers
189(1)
Ulcers Due to Arterial Insufficiency
189(1)
Diabetic Ulcers
190(1)
Clinical Use of HBO in Diabetic Foot
191(1)
Guideline for the Use of HBO in the Treatment of Diabetic Foot Ulcers
192(1)
Venous Ulcers
193(2)
Decubitus Ulcers
195(1)
Infected Wounds
195(1)
Frostbite
195(1)
Spider Bite
196(1)
HBO for Inflammatory Bowel Disease
197(1)
HBO as an Aid to the Survival of Skin Flaps and Free Skin Grafts
197(1)
Basic Considerations
197(1)
Animal Experimental Studies
198(1)
Comparison and Combination of HBO with Other Methods for Enhancing Flap Survival
199(1)
Clinical Applications
199(1)
Conclusion
200(1)
HBO as an Adjunct in the Treatment of Thermal Burns
200(1)
Basic Considerations
200(1)
Experimental Studies
201(1)
Clinical Applications
201(1)
Conclusion
202(1)
Applications of HBO in Dermatology
202(1)
Necrobiosis Lipoidica Diabeticorum
202(1)
Pyoderma Gangrenosum
202(1)
Purpura Fulminans
203(1)
Toxic Epidermal Necrolysis
203(1)
Psoriasis
203(1)
Scleroderma
203(1)
References
204(3)
17 HBO Therapy in the Management of Radionecrosis
207(14)
K. K. Jain
Intoduction
207(1)
Radiation Physics
207(1)
Unit of Radiation
207(1)
Radiation Biology
208(1)
Radiation Pathology
208(1)
Clinicopathological Correlations
208(1)
Effect of Radiation on Blood Vessels
208(1)
Effect on Soft Tissues
208(1)
Radiation Effects on the Nervous System
208(1)
Radiation Effects on the Bone
209(1)
HBO Therapy for Radionecrosis
209(1)
Effect of HBO on Radiation Damage to Skin and Mucous Membranes
209(1)
Rationale for Clinical Application
209(1)
Management of Osteoradionecrosis
210(1)
Basic Studies
210(1)
Osteoradionecrosis of the Mandible
211(1)
Osteonecrosis of the Temporal Bone
212(1)
Osteoradionecrosis of the Chest Wall
212(1)
Osteoradionecrosis of the Vertebrae
212(1)
Management of Radionecrosis of CNS
212(2)
Management of Radionecrosis of Soft Tissues
214(2)
Effect of HBO on Cancer Recurrence
216(1)
Conclusion
217(1)
References
217(4)
18 The Use of HBO in Treating Neurological Disorders
221(16)
K. K. Jain
Introduction
221(1)
Effect of HBO on Cerebral Metabolism
221(1)
Effect of HBO on Cerebral Blood Row
222(2)
Effect of HBO on the Blood--Brain Barrier
224(1)
Effect of HBO on Oxygen Tension in the Cerebrospinal fluid
224(1)
Rationale for the Use of HBO in Neurological Disorders
225(1)
Cerebral Hypoxia
225(1)
Cerebral Edema
225(1)
Role of HBO in Neuroprotection
226(2)
Indications for the Use of HBO in Neurological Disorders
228(1)
Clinical Neurological Assessment of Response to HBO
229(1)
Comatose Patients
229(1)
Paraplegics
229(1)
Hemiplegics (Stroke Patients)
230(1)
Diagnostic Procedures Used for Assessing the Effect of HBO
230(1)
Electrophysiological Studies
230(1)
Cerebral Blood Flow
231(1)
Computerized Tomography
232(1)
Magnetic Resonance Imaging
232(1)
Positron Emission Tomography
233(1)
Single Photon Emission Computed Tomography
233(1)
References
234(3)
19 Role of Hyperbaric Oxygenation in the Management of Stroke
237(32)
K. K. Jain
Introduction
237(1)
Epidemiology of Stroke
238(1)
Risk Factors for Stroke
238(1)
Pathophysiology of Stroke
239(1)
Causes of Stroke
239(1)
Changes in the Brain During Ischemic Stroke
240(1)
Clinicopathological Correlations
240(1)
Structure of a Cerebral Infarct
240(2)
Cerebral Metabolism in Ischemia
242(2)
Molecular Mechanism in the Pathogenesis of Stroke
244(1)
Gene Expression in Response to Cerebral Ischemia
244(1)
Induction of Heat Shock Proteins
244(1)
Role of Cytokines and Adhesion Molecules in Stroke
244(1)
DNA Damage and Repair in Cerebral Ischemia
244(1)
Role of Neurotrophic Factors
244(1)
Classification of Ischemic Cerebrovascular Disease
245(1)
Recovery from Stroke
245(1)
Complications of Stroke
246(1)
Sequelae of Stroke
246(1)
Vascular Dementia
247(1)
Diagnosis of Stroke
247(1)
Stroke Scales
248(1)
Barthel Index
248(1)
Rankin Scale
248(1)
National Institutes of Health Stroke Scale
248(1)
Unified Neurological Stroke Scale
248(1)
Canadian Neurological Scale
249(1)
Evaluation of Various Scales
249(1)
An Overview of the Conventional Management of Stroke
249(1)
Acute Ischemic Stroke
249(1)
Neuroprotectives
250(2)
Management of the Chronic Poststroke Stage
252(1)
Management of Spasticity
252(1)
Role of HBO in the Management of Acute Stroke
253(1)
HBO in Relation to Cerebral Ischemia and Free Radicals
254(1)
Animal Experiments
254(3)
Neuroprotective Effect of HBO Preconditioning
257(1)
Review of Clinical Studies
258(4)
HBO as a Supplement to Rehabilitation of Stroke Patients
262(3)
Conclusions of the Effects of HBO in Stroke Patients
265(1)
Future Prospects
266(1)
References
266(3)
20 HBO Therapy in Global Cerebral Ischemia/Anoxia and Coma
269(52)
Paul G. Harch
Introduction
269(1)
Pathophysiology
270(1)
Rational Basis of HBO Therapy
271(27)
Review of Animal Experimental Studies
298(2)
Review of Human Clinical Studies
300(4)
Case Studies
304(1)
Patient 1 HBO Treatment for Coma Due to Traumatic Brain Injury
304(3)
Patient 2 Near Drowning, Chronic Phase
307(1)
Patient 3 Near Drowning, Chronic Phase
308(1)
Patient 4 Battered Child Syndrome
309(2)
Conclusion
311(3)
References
314(7)
21 HBO Therapy in Neurosurgery
321(20)
K. K. Jain
Introduction
321(1)
Role of HBO in the Management of Traumatic Brain Injury: TBI
321(1)
Mechanism of Action of HBO in TBI
322(1)
Effect of HBO on ICP in Acute TBI
322(1)
Effect of HBO Therapy in Chronic Sequelae of TBI
323(1)
Experimental and Clinical Studies of HBO in TBI
323(2)
Controlled Clinical Trials of HBO for TBI
325(1)
Use of HBO for TBI in Clinical Practice
326(1)
Conclusions
326(1)
Role of HBO in the Management of Spinal Cord Injury
326(1)
Effects of Spinal Cord Injury
327(1)
Rationale of the Use of HBO in SCI
327(1)
Animal Experimental Studies of HBO in SCI
327(1)
Clinical Studies of HBO in SCI
328(1)
Role of HBO in Rehabilitation of SCI Patients
329(1)
Role of HBO in Compressive and Ischemic Lesions of the Spinal Cord
329(1)
Conclusions About Use of HBO in SCI
330(1)
HBO as an Adjunct to Radiotherapy of Brain Tumors
330(1)
Role of HBO in the Management of CNS Infections
331(1)
Role of HBO in Cerebrovascular Surgery
332(5)
Neuroprotection During Neurosurgery
337(1)
Conclusion
337(1)
References
338(3)
22 Oxygen Treatment for Multiple Sclerosis Patients
341(10)
Philip B. James
Introduction
341(1)
Pathophysiology
342(1)
Rationale for Hyperbaric Oxygen Treatment
342(3)
Clinical Trials of HBO in Multiple Sclerosis
345(4)
Conclusion
349(1)
References
349(2)
23 HBO in the Management of Cerebral Palsy
Paul G. Harch
351(1)
Introduction: Causes of Cerebral Palsy
351(1)
Oxygen Therapy in the Neonatal Period
351(2)
Treatment of Cerebral Palsy with HBO
353(1)
Published Clinical Trials
354(1)
The United States Army Study on Adjunctive HBO Treatment of Children with Cerebral Anoxic Injury
355(1)
The New Delhi Study of HBOT in CP
356(1)
Unpublished Studies
356(1)
The Cornell Study
356(1)
Comparative Effectiveness Studies
356(1)
Recent Studies (Since 2007)
357(1)
Side Effects
357(1)
Case Reports
358(1)
Patient 1 Cerebral Palsy
358(1)
Patient 2 Cerebral Palsy
359(2)
Conclusions
361(2)
References
363(2)
24 HBO Therapy in Miscellaneous Neurological Disorders
365(6)
K. K. Jain
Introduction
365(1)
HBO in the Treatment of Benign Intracranial Hypertension
365(1)
Peripheral Neuropathy
366(1)
HBO for the Treatment of Peripheral Neuropathic Pain
366(1)
HBO for Treatment of Drug-Induced Neuropathy
366(1)
HBO for the Treatment of Trigeminal Neuralgia
367(1)
HBO in Susac's Syndrome
367(1)
Cerebral Malaria
367(1)
Vascular Headaches
367(1)
Rationale for the Use of HBO in Vascular Headaches
367(1)
Current Status of Use of HBO in Vascular Headaches
368(1)
HBO for Autism Spectrum Disorder
368(1)
Neurological Disorders in Which HBO Has Not Been Found to Be Useful
368(1)
Dementia Due to Degenerative Disorders of the Brain
368(1)
HBO in the Management of Neuromuscular Disorders
369(1)
References
370(1)
25 HBO Therapy in Cardiovascular Diseases
371(22)
K. K. Jain
Introduction
371(1)
Pathophysiology
371(1)
Risk Factors
371(1)
Hypoxia, Hyperoxia, and Atherosclerosis
371(1)
Hyperbaric Oxygenation in Cardiology
372(1)
Effect of Hypoxia, Hyperoxia, and Hyperbaric Environments on Cardiovascular Function
372(1)
Metabolic Effects of HBO on the Heart
372(1)
Role of HBO in Experimental Myocardial Infarction
373(1)
Clinical Applications of HBO in Cardiology
373(1)
Acute Myocardial Infarction
373(3)
Combination of HBO and Thrombolysis
376(1)
Chronic Ischemic Heart Disease (Angina Pectoris)
376(1)
Cardiac Arrhythmias
377(1)
Heart Failure
377(1)
Cardiac Resuscitation
377(1)
HBO as an Adjunct to Cardiac Surgery
377(1)
Experimental Studies
377(1)
Human Cardiac Surgery
378(1)
Protective Effect of HBO Preconditioning in Cardiac Surgery
379(1)
CNS Complications of Cardiac Surgery
379(1)
HBO in Preventive Cardiology
380(1)
Prevention and Rehabilitation of Coronary Artery Disease
380(1)
Physical Training of Patients with Chronic Myocardial Insufficiency
380(1)
Conclusion and Comments
380(1)
HBO in Shock
380(1)
Pathophysiology of Shock
380(1)
Oxygen Delivery by Blood
380(1)
Traumatic and Hypovolemic Shock
381(1)
Cardiogenic Shock
381(1)
Peripheral Vascular Disease
381(1)
Causes
381(1)
Symptoms and Signs
382(1)
Pathophysiology of Limb Ischemia
382(1)
Biochemical Changes in Skeletal Muscle in Ischemia and Response to Exercise
382(1)
Clinical and Laboratory Assessment of Patients with Peripheral Vascular Disease
383(1)
General Management of PVD Patients
384(1)
Drug Therapy
384(1)
Exercise Therapy
384(1)
Surgery
384(1)
Role of HBO in the Management of Peripheral Vascular Disease
385(4)
Role of HBO in Miscellaneous Arteriopathies
389(1)
HBO as an Adjunct to Peripheral Vascular Surgery
389(1)
Conclusions Regarding the Role of HBO in Peripheral Vascular Disease
390(1)
References
390(3)
26 HBO Therapy in Hematology and Immunology
393(10)
K. K. Jain
Introduction
393(1)
Effect of HBO on Red Blood Cells
393(1)
Deformability
393(1)
Oxygen Exchange
394(1)
Structure and Biochemistry
395(1)
Effect of HBO on Stored Blood
395(1)
Hemoglobin
395(1)
Erythropoiesis
396(1)
Effect of HBO on Hemorheology in Human Patients
396(1)
Effect of HBO on Leukocytes
396(1)
Effect of HBO on Platelets and Coagulation
396(1)
Effect of HBO on Stem Cells
396(1)
Effect of HBO Treatment on the Immune System
397(1)
Effect of HBO Treatment on Plasma and Blood Volume
398(1)
The Use of HBO in Conjunction with Oxygen Carriers
399(1)
Clinical Applications of HBO in Disorders of the Blood
399(1)
Hypovolemia and Acute Anemia Due to Blood Loss
399(1)
Hemolytic Anemia
400(1)
Potential Benefits of HBO in Cerebrovascular Diseases Due to Blood Disorders
400(1)
Contraindication: Congenital Spherocytosis
400(1)
References
401(2)
27 HBO Therapy in Gastroenterology
403(14)
K. K. Jain
Introduction
403(1)
HBO in Peptic Ulceration
403(1)
Pathophysiology and Rationale of HBO Therapy
403(1)
Experimental Studies in Animals
404(1)
Clinical Assessment of HBO in Gastric and Duodenal Ulcer Patients
404(1)
HBO in the Treatment of Intestinal Obstruction
404(1)
Basic Considerations and Rationale of HBO Therapy
404(1)
Experimental Studies in Animals
405(1)
HBO Therapy in Adynamic Ileus
406(1)
HBO in Adhesive Intestinal Obstruction
406(1)
Methods
407(1)
HBO in Chronic Idiopathic Intestinal Pseudo-obstruction
407(1)
HBO in Inflammatory Bowel Disease
407(1)
Ulcerative Colitis and Crohn's Disease
407(1)
Mechanism of Effectiveness of HBO in Ulcerative Colitis
408(1)
HBO in Infections of the Gastrointestinal Tract
408(1)
Toxic Megacolon
408(1)
Pseudomembranous Colitis
409(1)
Necrotizing Enterocolitis
409(1)
Radiation Enterocolitis
409(1)
HBO in Pneumatosis Intestinalis
409(1)
Pathophysiology of Pneumatosis Cystoides Intestinalis
409(1)
Rationale for HBO Therapy
410(1)
Clinical Experience
410(1)
HBO in Ischemic Disorders of the Intestine
410(1)
Use of Hyperbaric Therapy in Removal of Entrapped Intestinal Balloons
411(1)
HBO in Acute Pancreatitis
411(1)
Animal Experimental Studies of HBO in Acute Pancreatitis
411(1)
Clinical Applications of HBO in Acute Pancreatitis
411(1)
HBO in Diseases of the Liver
412(1)
Effect of HBO on the Normal Liver
412(1)
Effect of HBO on Experimentally Induced Hepatic Disorders in Animals
412(1)
Clinical Applications
412(1)
Conclusions Regarding the Use of HBO in Gastroenterology
413(1)
References
414(3)
28 HBO and Endocrinology
417(6)
K. K. Jain
Introduction
417(1)
Thyroid Glands
417(1)
Glucocorticoid Receptors
417(1)
Adrenocortical Function
417(1)
Epinephrine/Norepinephrine
418(1)
Prostaglandins
418(1)
Testosterone
418(1)
Clinical Applications
419(1)
Thyroid Disease
419(1)
Diabetes Mellitus
419(1)
Conclusion
420(1)
References
420(3)
29 HBO and Pulmonary Disorders
423(6)
K. K. Jain
Introduction
423(1)
Effects of HBO on Lungs
423(1)
Arterial and Pulmonary Arterial Hemodynamics
423(1)
Lung Mechanics and Pulmonary Gas Exchange
424(1)
Pulmonary Oxygen Toxicity
424(1)
Clinical Applications
425(1)
Respiratory Insufficiency
425(1)
Bronchial Asthma
426(1)
Bronchitis
426(1)
Inflammatory Processes of the Lungs
426(1)
Pulmonary Embolism
426(1)
Pulmonary Edema
426(1)
Mechanism of Action of HBO in Type II Decompression Syndrome
427(1)
Contraindications for the Use of HBO
427(1)
Nitrogen Dioxide Poisoning
427(1)
Paraquat Poisoning
427(1)
Emphysema
427(1)
Shock Lung
427(1)
Pneumothorax
427(1)
Conclusion
428(1)
References
428(1)
30 Hyperbaric Oxygenation in Traumatology and Orthopedics
429(14)
K. K. Jain
Introduction
429(1)
Crush Injuries
429(1)
Pathophysiology
430(1)
Diagnosis
430(1)
Treatment
430(1)
Role of HBO in Treatment
430(1)
Traumatic Ischemia
431(2)
Compartment Syndromes
433(1)
HBO for High Pressure Water Gun Injection Injury
433(1)
Peripheral Nerve Injuries
433(1)
Rationale for the Use of HBO
434(1)
Experimental Studies
434(1)
Clinical Applications
435(1)
Concluding Remarks
435(1)
Fractures
435(1)
Basic and Experimental Considerations
435(1)
Clinical Experience
436(1)
Bone Fractures with Arterial Injuries
436(1)
Traumatic Amputations and Reimplantations of Body Parts
436(1)
Reimplantation of Limbs
436(1)
Reimplantation of Other Body Parts
437(1)
Role of HBO in Battle Casualties
437(1)
Effect of HBO on Osteogenesis
437(1)
HBO for Treatment of Osteonecrosis (Aseptic Necrosis)
437(1)
HBO Therapy of Osteonecrosis
438(2)
Rheumatoid Arthritis
440(1)
Basic Considerations
440(1)
Rationale of Use of HBO in Rheumatoid Arthritis
440(1)
Clinical Applications
441(1)
Conclusion
441(1)
References
441(2)
31 HBO Therapy in Otolaryngology
443(14)
K. K. Jain
Introduction
443(1)
Tinnitus
443(2)
Sudden Deafness
445(1)
Role of HBO in the Management of Sudden Deafness
445(1)
Rationale for HBO Therapy in Sudden Deafness
445(1)
Acute Acoustic Trauma
446(3)
Concluding Remarks About the Use of HBO in Hearing Loss
449(2)
Effect of HBO in Preventing Hearing Impairment from Chronic Noise Exposure
451(1)
Miscellaneous Disturbances of the Inner Ear
451(1)
Neuro-otological Vascular Disturbances
451(1)
Meniere's Disease
452(1)
Facial Palsy
453(1)
Otological Complications of HBO Therapy
453(1)
Miscellaneous Conditions in Head and Neck Area
453(1)
Malignant Otitis Externa
453(1)
Aphonia Due to Chronic Laryngitis
454(1)
Conclusion
454(1)
References
454(3)
32 HBO Therapy and Ophthalmology
457(28)
Heather Murphy-Lavoie
Tracy LeGros
Frank K. Butler Jr.
K. K. Jain
Introduction
457(1)
Review of Pertinent Anatomy and Physiology of the Eye
458(1)
The Process of Vision
458(1)
Factors Affecting Vision
458(1)
Retinal Blood Supply
458(1)
Ocular Oxygen Tension
458(1)
Physiology of the Eye in Hyperoxic Conditions
458(1)
Adverse Effects of Hyperoxia
459(1)
Retinal Oxygen Toxicity
459(1)
Lenticular Oxygen Toxicity
460(1)
Ocular Contraindications to Hyperbaric Oxygen Therapy
461(1)
Pre-HBOT Ocular Examination
461(1)
HBO in the Treatment of Diseases of the Eye
461(1)
Recommended Indications
461(7)
Potential Indications for HBOT in Ophthalmology
468(6)
Other Reported Uses
474(3)
Emergency HBO in Patients with Acute Vision Loss
477(1)
Conclusion
478(1)
References
478(7)
33 Hyperbaric Oxygenation in Obstetrics and Gynecology
485(6)
K. K. Jain
Introduction
485(1)
HBO and Risk of Congenital Malformations
485(1)
Role of HBO in Obstetrics
486(1)
Experimental Studies
486(1)
Clinical Applications
486(1)
Use of HBO for Medical Conditions in Pregnancy
487(1)
Acute Carbon Monoxide Poisoning During Pregnancy
487(1)
Diabetes
487(1)
Management of Pregnancy and Delivery in Women with Heart Disease
487(1)
Applications of HBO in Neonatology
487(1)
HBO in Gynecology
488(1)
Animal Experimental Studies
488(1)
Clinical Applications in Gynecology
488(1)
Conclusion
488(1)
References
489(2)
34 Use of Hyperbaric Oxygenation (HBO) in Neonatal Patients
491(8)
E. Cuauhtemoc Sanchez-Rodriguez
Introduction
491(1)
Hypoxic--Ischemic Encephalopathy of the Newborn
492(1)
Uses of Hyperbaric Oxygenation in Hypoxic--Ischemic Encephalopathy and Necrotizing Enterocolitis of the Neonate
492(1)
Use of Hyperbaric Oxygenation in Neonates
493(1)
Results
494(1)
Discussion
495(1)
References
495(4)
35 Hyperbaric Oxygenation in Geriatrics
499(6)
K. K. Jain
Introduction
499(1)
Physiology of Aging
499(1)
Theories of Aging
499(2)
Changes in the Brain with Aging
501(1)
Applications of HBO in Geriatrics
502(1)
Rationale
502(2)
Safety of HBO Treatments in the Elderly
504(1)
Conclusion
504(1)
References
504(1)
36 HBO as an Adjuvant in Rehabilitation and Sports Medicine
505(6)
K. K. Jain
Introduction
505(1)
Role of HBO in Rehabilitation
505(1)
Indications
505(1)
Advantages
506(1)
Applications of HBO in Rehabilitation of Neurological Disorders
506(1)
Rehabilitation of patients with CNS injuries
506(1)
Role of HBO in Rehabilitation after Myocardial Infarction
506(1)
HBO as an Adjunct to Rehabilitation in Peripheral Vascular Disease
506(1)
HBO as an Adjunct to Rehabilitation of Limb Amputees
507(1)
HBO for Treatment of Sports Injuries
507(1)
HBO as an Adjunct to Sports Training
508(1)
Future Prospects
509(1)
References
509(2)
37 Nursing and Hyperbaric Medicine
511(12)
Valerie A. Larson-Lohr
History
511(2)
The Nursing Process
513(1)
Hyperbaric Patient Education
513(8)
Hyperbaric Nursing Research
521(1)
References
521(2)
38 Role of HBO in Enhancing Cancer Radiosensitivity
523(10)
K. K. Jain
Introduction
523(1)
Role of Hypoxia in Tumors
523(1)
Rationale of Use of HBO as Adjunct to Radiotherapy
524(1)
Experimental Studies of the Radiosensitizing Effect of HBO
524(1)
Clinical Studies of HBO as Radiation Sensitizer
525(1)
Carcinoma of the Cervix
525(1)
Head and Neck Cancer
525(1)
Carcinoma of the Lung
526(1)
Carcinoma of the Bladder
526(1)
Malignant Melanoma
526(1)
Malignant Glioma
526(2)
Advantages of HBO as an Adjunct to Radiotherapy
528(1)
Limitations of HBO as Adjunct to Radiotherapy of Cancer
528(1)
Drawbacks of HBO as Adjunct to Radiotherapy of Cancer
528(1)
Alternative Methods for Enhancing Radiosensitivity of Cancer
528(1)
Combination of Other Methods with HBO and Irradiation for Cancer
529(1)
Hyperthermia
529(1)
Hypothermia
529(1)
Vasodilators
529(1)
Induced Anemia and Red Cell Infusion
529(1)
Radiation Sensitizing Agents
529(1)
Use of Perfluorochemicals as Oxygen Carriers
529(1)
HBO and Antineoplastic Agents
529(1)
HBO and Photodynamic Therapy
530(1)
Conclusion
530(1)
References
530(3)
39 HBO Therapy and Organ Transplants
533(8)
H. Alan Wyatt
Background
533(1)
Role of HBO
534(1)
Ischemia-Reperfusion Injury
534(1)
Inflammation
534(1)
Lung Transplants
535(1)
Pancreas Transplants
535(1)
Renal Transplants
536(1)
Liver Transplants
536(1)
Face Transplants
537(1)
Hand Transplants
537(1)
Miscellaneous Organs and Tissues
537(1)
Clinical Applications
538(1)
Conclusion
538(1)
References
538(3)
40 Hyperbaric Oxygen Pretreatment and Preconditioning
541(4)
Gerardo Bosco
Enrico M. Camporesi
Introduction
541(1)
Hyperbaric Medicine Perspective
541(1)
Diving Medicine
542(1)
References
543(2)
41 Anesthesia in the Hyperbaric Environment
545(6)
Enrico M. Camporesi
Historical Perspective
545(1)
Current Indications
546(1)
Physical Considerations Concerning Anesthetic
546(1)
Physiological Considerations
546(1)
Cardiovascular Effects
547(1)
Central Nervous System
547(1)
Nitrous Oxide Anesthesia
547(1)
Intravenous Anesthesia
548(1)
Pharmacokinetics in the Hyperbaric Environment
548(1)
Practical Aspects of Anesthesia in the Pressure Chamber
548(1)
Noise
548(1)
Airway Equipment
548(1)
Ventilators
548(1)
Monitoring
549(1)
Prophylactic Myringotomy to Prevent Middle Ear Barotrauma
549(1)
Conclusion
550(1)
References
550(1)
42 Hyperbaric Oxygen in Resuscitation
551(16)
Keith Van Meter
Introduction
551(2)
Indications
553(1)
Cardiopulmonary Resuscitation
553(1)
Case Studies
554(1)
Case 1
554(4)
Case 2
558(4)
Discussion
562(1)
Future Applications
563(1)
Conclusion
564(1)
References
565(2)
43 HBO in Military Medicine
567(12)
Fabio Faralli
Alberto Fiorito
Gerardo Bosco
Hyperbaric Oxygen Therapy and Combat Medicine
567(1)
Gas Gangrene: Crush Injuries and Traumatic Wounds
568(1)
Exceptional Loss of Blood
568(1)
Burns
568(1)
Postconcussion Syndrome, Traumatic Brain Injuries, Posttraumatic Stress Disorders
569(1)
Hearing Loss and Tinnitus
570(1)
Spinal Cord Injury
570(1)
Hyperbaric Oxygen Therapy and Military Response to Natural Catastrophes
570(1)
Hyperbaric Activities in Military Environment
571(1)
Offensive Activities or Activities Carried out During Wartime
571(1)
Defensive Activities or Activities Carried out During Peacetime
572(1)
Field of HBO Application in Military Diving Medicine
573(1)
Military Diving Operations
573(1)
Diving Methods
573(1)
Employee's Safety
573(1)
Personnel Training
573(1)
Personnel Recruitment
573(1)
Submarine Medicine
573(1)
Submarines' Rescue
573(1)
Technical Aspects of Rescue Operations
573(1)
Transfer Under Pressure
574(1)
References
574(5)
Part III Hyperbaric Medicine as a Specialty
44 Training and Practice of Hyperbaric Medicine
579(4)
K. K. Jain
Introduction
579(1)
Relation of Hyperbaric Medicine to Other Medical Specialties
580(1)
Hyperbaric Medicine and Diving Medicine
580(1)
Training in Hyperbaric Medicine
580(1)
Admission Requirements
580(1)
Training Program
580(1)
Examinations
580(1)
Proposal for a Curriculum for a Diploma Course in Hyperbaric and Diving Medicine
581(1)
Training of Nonphysician Healthcare Personnel for Hyperbaric Medicine
581(1)
Practice of Hyperbaric Medicine
581(1)
Economic Aspects
582(1)
Conclusion
582(1)
45 Research in Hyperbaric Medicine
583(6)
K. K. Jain
Introduction
583(1)
Basic Research in HBO
583(1)
Animal Experimental Studies
584(1)
Application of Biotechnologies in Hyperbaric Medicine
584(1)
Biomarkers of Effect of HBO
584(1)
Action of HBO on Gene Expression
585(1)
HBO as Adjunct to Cell therapy and Regenerative Medicine
586(1)
Nanobiotechnology and HBO
586(1)
Clinical Trials of HBO Therapy
587(1)
Problems with Clinical Trials of HBO
587(1)
Ethical Aspects of Clinical Trials with HBO
588(1)
Conclusion
588(1)
References
588(1)
46 Personalized Hyperbaric Medicine
589(4)
K. K. Jain
Introduction
589(1)
Molecular Diagnostics as Guide to HBO Therapy
590(1)
Role of Sequencing in Personalized Medicine
590(1)
Biomarkers for Personalized HBO Therapy
591(1)
Imaging for Personalized HBO Therapy
591(1)
Brain Imaging as Guide to Therapy of Multiple Sclerosis
591(1)
Imaging Tumor Hypoxia for Personalized Cancer Therapy
591(1)
Pharmacogenomics and Pharmacogenetics of HBO
592(1)
Oxygen Toxicity and Genes
592(1)
Susceptibility to HBO-Induced Cataract Formation
592(1)
Economical Aspects of Personalized HBO Therapy
592(1)
Conclusion
592(1)
References
592(1)
47 The Future of Hyperbaric Medicine
593(4)
K. K. Jain
Introduction to Future Medicine
593(1)
Important Medical Advances in the Next Decade
593(1)
Advances in Surgery
594(1)
Important Areas for Future Development
594(1)
Role of HBO in Future Medicine
595(1)
Role of Hyperbaric Oxygen in the Multidisciplinary Healthcare Systems of the Future
595(1)
Future Needs in Hyperbaric Medicine
595(1)
References
596(1)
48 Ethical Issues, Standards, and Quality Control in the Practice of Hyperbaric Medicine
597(12)
Caroline E. Fife
Kristen A. Eckert
Wilbur Thomas Workman
Alternative Medical Treatments and Off-Label Use of Hyperbaric Oxygen
598(1)
The Risks of the Public Information Gap
598(1)
Is There an Alternative to HBOT?
599(1)
Safety and Fire Hazard Issues from Misuse of Hyperbaric Chambers
599(3)
The Controversy of Low Pressure Oxygen
602(1)
The "Chamber" Effect
602(1)
Ethical Challenges with HBOT Clinical Trial Design
603(1)
Informed Consent
604(1)
Desperate Measures
604(1)
HBOT Fraud
605(1)
HBOT Market Regulations
605(1)
Food, Drug, and Cosmetic Act (FDC) 510(k) Clearance
605(1)
National Hyperbaric Oxygen Therapy Registry
606(1)
Conclusion
606(1)
References
607(2)
49 Worldwide Overview of Hyperbaric Medicine
609(6)
K. K. Jain
Introduction
609(1)
Hyperbaric Medicine in China
609(1)
Hyperbaric Medicine in Japan
610(1)
Hyperbaric Medicine in Russia
611(1)
Hyperbaric Medicine in Germany
612(1)
World Distribution of Hyperbaric Facilities
613(1)
Conclusion
614(1)
Reference
614(1)
50 Hyperbaric Medicine in the United States
615(8)
Thomas M. Bozzuto
Introduction
615(2)
American College of Hyperbaric Medicine
617(2)
National Board of Diving and Hyperbaric Medical Technology
619(1)
Baromedical Nurses Association
619(1)
Indications for Use of Hyperbaric Oxygen
620(1)
Resources
620(1)
Organizations for Subspecialty Certification
621(1)
Currently Offered Fellowship Training Locations in Undersea and Hyperbaric Medicine
621(2)
51 Hyperbaric Medicine in Latin America
623(4)
Cuauhtemoc Sanchez-Rodriguez
History
623(1)
Introduction
623(1)
Existing General Standards
624(1)
Responsible Existing Authorities
624(1)
Industry
624(1)
Labor
624(1)
Health
624(1)
Insurance
624(1)
Latin American Consensus
624(1)
Implementation of Minimum Standards and Regulations
625(2)
Index 627
Kewal K. Jain, MD

Basel

Switzerland