This book provides an up-to-date overview on the epidemiology, clinical presentation, and imaging characteristics of sacral tumors, discusses the available treatment options, and reports the published outcomes. The diagnostic roles of conventional radiology, CT, and MRI are thoroughly described and imaging appearances are compared with the histologic features. The coverage of therapeutic approaches includes chemotherapy, radiotherapy, radiosurgery, and surgery (partial or total sacrectomy and spinopelvic reconstruction). Special attention is paid to the specific anatomic constraints that make tumors in this region of the spine more difficult to manage effectively than those in the extremities and the mobile portions of the spine.All components of the sacrum can give rise to benign or malignant tumors, which pose significant diagnostic and therapeutic challenges. Although these tumors are often diagnosed at an advanced stage, good clinical outcomes may be achieved if an aggressiv
e multidisciplinary approach is used. This book will be of value for a range of practitioners; it will assist in prompt diagnosis and help to overcome lack of familiarity with the required treatment strategies.
PART 1: GENERAL ASPECTS1) Surgical Anatomy of the Sacrum2) Clinic and Neurologic Manifestations of Sacral Lesions3) Epidemiology4) Diagnostic Imaging5) Staging and biopsy6) HistopathologyPART 2: BENIGN LESIONS7) Giant cell tumor8) Osteoblastoma9) Osteoid osteoma10) Aneurysmal bone cyst11) Scwannoma12) Exostosis13) Hemangioma14) Other benign rare entitiesPART 3: MALIGNANT LESIONS15) Metastasis16) Chordoma17) Osteosarcoma18) Ewing"s Sarcoma19) Myeloma20) Lymphoma21) Condrosarcoma22) Other malignant rare entitiesPART 4: TREATMENTS23) Surgical Approaches to the Sacrum24) Partial and total sacrectomy25) Sacral Biomechanics and Reconstruction26) Soft tissue reconstruction after sacral surgery27) Embolization of Sacral Lesions28) Radiation Therapy of Sacral Neoplasms
PART 1: GENERAL ASPECTS: Surgical Anatomy of the Sacrum.- Clinical and
Neurologic Manifestations of Sacral Lesions.- Epidemiology.- Diagnostic
Imaging.- Staging and Biopsy.- Histopathology.- PART 2: BENIGN LESIONS: Giant
Cell Tumor.- Osteoblastoma.- Osteoid osteoma.- Aneurysmal bone cyst.-
Scwannoma.- Exostosis.- Hemangioma.- Other benign rare entities.- PART 3:
MALIGNANT LESIONS: Metastasis.- Chordoma.- Osteosarcoma.- Ewings Sarcoma.-
Myeloma.- Lymphoma.- Condrosarcoma.- Other malignant rare entities.- PART 4:
TREATMENTS: Surgical Approaches to the Sacrum.- Partial and total
sacrectomy.- Sacral Biomechanics and Reconstruction.- Soft tissue
reconstruction after sacral surgery.- Embolization of Sacral Lesions.-
Radiation Therapy of Sacral Neoplasms.
1. Pietro Ruggieri, MD PhD Department of Orthopedics and Orthopedic Oncology University of Padova, Italy
2. Andrea Angelini, MD,PhD Department of Orthopedics and Orthopedic Oncology University of Padova, Italy
3. Daniel Vanel, MD Department of Pathology Istituto Ortopedico Rizzoli, Bologna, Italy
4. Piero Picci, MD Laboratory of Experimental Oncology Musculoskeletal Oncology, Istituto Ortopedico Rizzoli, Bologna, Italy
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