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Twin-to-Twin Transfusion Syndrome [Kietas viršelis]

  • Formatas: Hardback, 186 pages, aukštis x plotis: 279x216 mm, weight: 380 g, 62 Halftones, color; 33 Illustrations
  • Išleidimo metai: 31-Mar-2013
  • Leidėjas: Jaypee Brothers Medical Publishers
  • ISBN-10: 9350903512
  • ISBN-13: 9789350903513
Kitos knygos pagal šią temą:
  • Formatas: Hardback, 186 pages, aukštis x plotis: 279x216 mm, weight: 380 g, 62 Halftones, color; 33 Illustrations
  • Išleidimo metai: 31-Mar-2013
  • Leidėjas: Jaypee Brothers Medical Publishers
  • ISBN-10: 9350903512
  • ISBN-13: 9789350903513
Kitos knygos pagal šią temą:
Twin-to-Twin Transfusion Syndrome (TTTS) is a rare condition that only occurs in identical twins when they are in the womb. It occurs when blood moves from one twin to the other, resulting in one twin having too little blood and the other with too much blood.





This concise guide describes the etiology, diagnosis and treatment of TTTS. Divided into six sections, the book begins with the history of the condition, then the basics, clinical features and diagnosis, to the most recent advances in its management and related ethical issues.





Edited by Professor Daniel W Skupski of Weill Medical College of Cornell University and New York Hospital Queens, USA, this practical guide includes nearly 100 full colour images and illustrations.





 





Key points









Concise guide to Twin-to-Twin Transfusion Syndrome (TTTS) Provides most up to date knowledge on etiology, diagnosis and treatment Edited by Daniel W Skupski of Cornell University and New York Hospital, Queens Includes nearly 100 images and illustrations
Contributors vii
Preface ix
Introduction xix
Section 1 Where did We Come from?
1 History
3(16)
Daniel W Skupski
Distant History
3(2)
Fetal Diagnosis and Therapy
5(2)
Laser Therapy
7(4)
Collaboration
11(8)
Section 2 Why does TTTS Occur?
2 The Hidden Costs of Monochorionicity
19(5)
Issac Blickstein
The Magnitude of the Problem
19(1)
Apparent and Hidden Costs of Monochorionic Twins
20(4)
Mode of Conception
20(1)
Diagnosis
20(1)
Fetal Growth
21(1)
Twin-to-Twin Transfusion Syndrome
21(1)
Single Fetal Death
21(1)
Cerebral Palsy
22(1)
Natural History of Monochorionic Pregnancies
22(1)
Preterm Birth
22(2)
3 Placentation
24(6)
Daniel W Skupski
Placental Anatomy
24(1)
Early Placental Development
25(1)
Chorionic Plate Architecture
26(1)
A Hypothesis Regarding Zygosity, Chorionicity, The Intertwin Membrane and Vascular Connections
27(3)
4 Pathophysiology
30(14)
David Danon
Nicholas M Fisk
Placental Pathophysiology
30(5)
Arteriovenous Anastomoses
30(2)
Superficial Anastomoses
32(1)
Intertwin Transfusion
33(1)
Early Development
34(1)
Fetal Pathophysiology
35(9)
Renovascular System
35(1)
Cardiovascular System
36(2)
Peripheral Doppler Abnormalities
38(1)
Endocrine Markers
38(6)
5 Color Injection and Digital Angiography
44(15)
Birgit Arabin
Ahmet Baschat
Explaining Clinical Symptoms of Monochorionic Twins through Postnatal Correlation with the Placenta
44(3)
Correlating Prenatal Sonographic and Intrauterine Laser Findings of Monochorionic Twins with the Placental Vasculature by Color Injections
47(1)
Computer Angiography of Placental Vessels in Monochorionic Multiples
48(11)
Section 3 What is TTTS?
6 Natural History
59(5)
Daniel W Skupski
Missteps
59(2)
Determining the Natural History of Twin-to-Twin Transfusion Syndrome
61(3)
7 Clinical Effects
64(22)
Ahmet Baschat
Birgit Arabin
The Monochorionic Placenta
64(15)
Signs and Effects of Volume Imbalance
65(12)
Signs and Effects of Nutrient Imbalance---Fetal Growth Discordance
77(1)
Discordant Fetal Anomalies
78(1)
Clinical Evolution and Implications for Surveillance and Risk Assessment
79(7)
8 Diagnosis
86(8)
Marieke Sueters
Kenneth J Moise Jr.
Diagnosis of Chorionicity
86(2)
First Trimester Ultrasound Examination
86(1)
Second Trimester Ultrasound Examination
86(1)
Risk Stratification for Monochorionic Twins
87(1)
Ultrasound Surveillance of the Monochorionic Twin Gestation
88(1)
Diagnosis of Twin-to-Twin Transfusion Syndrome
89(5)
9 Maternal Nutrition
94(6)
Julian E De Lia
Cresta W Jones
Methods
94(1)
Results
95(1)
Consequences
96(4)
10 The Cervix
100(7)
Shirlee Jaffe-Lifshitz
Daniel W Skupski
Risk of Spontaneous Preterm Birth in Twins
100(1)
Cervical Length and the Risk of Preterm Birth
100(1)
Interventions to Prevent Preterm Birth in the Setting of a Short Cervix
101(1)
Interventions for Short Cervix in the Setting of TTTS
102(1)
Pessary
103(4)
Section 4 When does TTTS Occur?
11 Acute Twin-to-Twin Transfusion Syndrome
107(7)
Daniel W Skupski
Etiology
107(2)
Incidence
109(1)
Literature Review
109(3)
Hypotheses
112(1)
Management
112(2)
12 Triplets
114(7)
Inna Landres
Daniel W Skupski
Prevalence of Feto-Fetal Transfusion Syndrome (FFTS) in Triplets
114(1)
FFTS in Dichorionic vs Monochorionic Triplets
114(1)
Outcomes with No Treatment
114(1)
Treatment Options
115(2)
Amnioreduction
115(1)
Laser Therapy
115(2)
Neonatal Follow-up
117(1)
Counseling and Ethical Considerations
117(1)
Unanswered Questions
117(4)
Section 5 How do We Treat TTTS?
13 Therapy
121(9)
Gihad E Chalouhi
Maria Angela Marangoni
Yves Ville
Treatment Options
121(1)
Amnioreduction
121(1)
Septostomy
122(1)
Laser Treatment
122(1)
Anesthesia
122(1)
Abdominal Entry
122(1)
Technique
122(2)
Operative Time
124(1)
Learning Curve
125(1)
Perioperative Care and Follow-up
125(1)
Surgical Failure
125(1)
Complications
126(4)
14 Neonatal Outcomes
130(12)
Enrico Lopriore
Jeanine van Klink
Dick Oepkes
Neonatal Mortality
130(1)
Neonatal Morbidity
130(12)
Neurologic Morbidity
130(5)
Cardiovascular Morbidity and Right Ventricular Outflow Tract Obstruction
135(1)
Renal Morbidity
135(1)
Hematologic Morbidity
136(1)
Antenatal Hypoxic-Ischemic Lesions
137(1)
Amniotic Band Syndrome
137(5)
15 Monitoring of Disease
142(11)
Dick Oepkes
Femke Slaghekke
Enrico Lopriore
Monitoring Stage I TTTS
142(2)
Monitoring TTTS Pregnancies Following Laser Surgery
143(1)
Complications: What to Look for
144(9)
Preterm Prelabor Rupture of Membranes
144(1)
Chorioamnion Separation
144(1)
Ruptured Intertwin Membrane
145(1)
Single Fetal Death: What to Do?
145(1)
Fetal Brain Damage and the Role of MRI
146(1)
Limb Reduction and Amniotic Bands
146(1)
Vasa Previa
147(1)
Residual Anastomoses after Laser
147(6)
16 Ethical Dimensions
153(6)
Laurence B McCullough
Frank A Chervenak
The Ethics of Non-Directive and Directive Counseling in the Informed Consent Process
153(6)
Ethically Justified Decision-Making Pathway
153(6)
Section 6 What's Next?
17 The Future
159(4)
Daniel W Skupski
Index 163
Daniel W Skupski MD

Professor, Department of Obstetrics and Gynecology, Weill Medical College of Cornell University; Associate Chairman, Department of Obstetrics and Gynecology, New York Hospital Queens, New York, USA