Fetal development in the mouse is routinely and increasingly utilized for advancing translational research and medical innovation for human obstetrical care. This is the first and only manual to provide necessary content on how this should be handled for accurate and effective data collection. Detailed descriptions and examples demonstrate how researchers and clinicians can use murine fetal and obstetrical data to improve future human applications in diseases such as infertility, recurrent pregnancy loss, intrauterine fetal growth restriction, placental insufficiency, and intrauterine fetal demise, as well as organ-specific developmental disease.
| Acknowledgements |
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vi | |
| Foreword |
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vii | |
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| Preface |
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ix | |
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Chapter 1 Implantation and Embryonic Imaging: Mouse until D4.5-9.5; Human 5-9 Weeks |
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1 | (14) |
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Chapter 2 Early Organogenesis and First Trimester: Mouse D10.5-12.5; Human 9-12 Weeks |
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15 | (16) |
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Chapter 3 Mid-Gestation and Second Trimester: Mouse D13.5-15.5; Human 13-27 Weeks |
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31 | (14) |
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Chapter 4 Central Nervous System and Facial Development: Mouse D13.5-15.5; Human 13-27 Weeks |
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45 | (14) |
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Chapter 5 Late-Gestation and Third Trimester: Mouse D16.5-18.5; Human 28-40 Weeks |
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59 | (16) |
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Chapter 6 Placenta Throughout Gestation |
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75 | (12) |
| Index |
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87 | |
Mary C. Peavey, MD, MSCI is Assistant Professor, Department of Obstetrics and Gynecology and Director, UNC, Fertility Preservation Program, Reproductive Endocrinology and Infertility, University of North Carolina, Raleigh, North Carolina, USA
Sarah K. Dotters-Katz, MD is Assistant Professor, Department of Obstetrics and Gynecology, Duke University, School of Medicine, Durham, North Carolina, USA
