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El. knyga: Veterans and Agent Orange: Update 2002

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  • Formatas: 638 pages
  • Išleidimo metai: 23-Jan-2003
  • Leidėjas: National Academies Press
  • Kalba: eng
  • ISBN-13: 9780309168564
Kitos knygos pagal šią temą:
Veterans and Agent Orange: Update 2002Didesnis paveikslėlis
  • Formatas: 638 pages
  • Išleidimo metai: 23-Jan-2003
  • Leidėjas: National Academies Press
  • Kalba: eng
  • ISBN-13: 9780309168564
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Put together by the National Academy of Science's Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides, this report assesses whether a statistical association exists between herbicide exposure and specific health outcomes, the increased risk of disease to Vietnam veterans, and the possible biological mechanisms or other causal relationships between herbicide exposure and disease. The committee concentrated on reviewing and interpreting epidemiological studies, although experimental studies related to causal relationships were explored as well. The committee considered the relationship of Agent Orange and other herbicides to the development of cancer, reproductive and developmental effects, neurobehavioral disorders, and other health effects. This volume presents the work of the committee updated as of 2002. Annotation ©2004 Book News, Inc., Portland, OR (booknews.com)
Executive Summary 1(2)
The Charge to the Committee
2(1)
The Committee's Approach to Its Charge
2(1)
The Committee's Evaluation
3(7)
Research Recommendations
10(2)
Introduction
12(8)
Charge to the Committee
13(1)
Conclusions of Previous Veterans and Agent Orange Reports
13(5)
Organization of this Report
18(1)
References
19(1)
Considerations in Evaluating the Evidence
20(10)
Choice of Health Outcomes
20(1)
Identification of Relevant Literature
20(2)
Committee's Approach to Its Charge
22(2)
Issues in Evaluating the Evidence
24(4)
References
28(2)
Toxicology
30(73)
Highlights of Previous Reports
31(1)
Toxicity Profile Update of 2,4-D
31(6)
Toxicity Profile Update of 2,4,5-T
37(1)
Toxicity Profile Update of Cacodylic Acid
38(2)
Toxicity Profile Update of Picloram
40(1)
Toxicity Profile Update of TCDD
40(36)
Summary of Toxicity Profiles
76(5)
Relevance to Human Health
81(1)
References
82(21)
Overview of Epidemiologic Studies
103(112)
Occupational Studies
104(11)
Environmental Studies
115(3)
Vietnam-Veteran Studies
118(76)
References
194(21)
Exposure Assessment
215(27)
Exposure Assessment for Epidemiology
215(2)
Occupational Exposure to Herbicides and TCDD
217(9)
Environmental Exposure to Herbicides and TCDD
226(3)
Military Use of Herbicides in Vietnam
229(3)
Exposure Assessment in Studies of Vietnam Veterans
232(3)
References
235(7)
Cancer
242(151)
Gastrointestinal Tract Tumors
243(16)
Hepatobiliary Cancers
259(5)
Nasopharyngeal Cancer
264(4)
Laryngeal Cancer
268(4)
Lung Cancer
272(6)
Bone and Joint Cancer
278(4)
Soft-Tissue Sarcomas
282(5)
Skin Cancer---Melanoma
287(8)
Skin Cancer---Basal-cell and Squamous-cell (Nonmelanoma)
295(5)
Breast Cancer
300(9)
Cancers of the Female Reproductive System
309(7)
Prostate Cancer
316(8)
Testicular Cancer
324(4)
Urinary Bladder Cancer
328(5)
Renal Cancer
333(5)
Brain Tumors
338(5)
Non-Hodgkin's Lymphoma
343(12)
Hodgkin's Disease
355(6)
Multiple Myeloma
361(5)
Leukemia
366(6)
Chronic Lymphocytic Leukemia
372(4)
Summary
376(5)
References
381(12)
Reproductive and Developmental Effects
393(54)
Birth Defects
393(12)
Fertility
405(4)
Spontaneous Abortion
409(12)
Stillbirth, Neonatal Death, and Infant Death
421(1)
Low Birthweight and Preterm Delivery
422(3)
Childhood Cancer
425(7)
Sex Ratio
432(6)
Summary
438(3)
References
441(6)
Neurobehavioral Disorders
447(30)
Cognitive and Neuropsychiatric Effects
448(4)
Motor or Coordination Dysfunction
452(13)
Chronic Persistent Peripheral Neuropathy
465(4)
Acute and Subacute Transient Peripheral Neuropathy
469(1)
Summary
470(2)
References
472(5)
Other Health Effects
477(46)
Chloracne
477(2)
Porphyria Cutanea Tarda
479(1)
Respiratory Disorders
480(3)
Immune System Disorders
483(2)
Diabetes
485(8)
Lipid and Lipoprotein Disorders
493(5)
Gastrointestinal and Digestive Disease, Including Liver Toxicity
498(4)
Circulatory Disorders
502(4)
AL Amyloidosis
506(2)
Endometriosis
508(2)
Thyroid Homeostasis
510(4)
Summary
514(5)
References
519(4)
Research Recommendations
523(16)
Vietnam-Veteran Studies
523(3)
Studies of the Vietnamese
526(1)
Other Research
526(1)
References
527(2)
APPENDIXES
A Agendas of Public Meetings
529(2)
B ICD-9 Codes for Health Outcomes of Interest
531(3)
C Committee and Staff Biographies
534(5)
Index 539


Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides (Fourth Biennial Update)
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